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Tuomas O. Kilpeläinen · SciRah

Researcher profile · Semantic Scholar

Tuomas O. Kilpeläinen

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Tuomas O. Kilpeläinen — researcher profile on SciRah

h-index: 47
Works: 159
Citations: 13K

Most-cited papers

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
M. Feitosa, A. Kraja, D. Chasman, Yun J. Sung +269 more
2018PLoS ONE764 citations Open access
Semantic Scholar
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
Zhe Wang, Andrew Emmerich, Nicolas J. Pillon, Timothy Moore +223 more
2022Nature Genetics195 citations Open access
Semantic Scholar
Obesity, unfavourable lifestyle and genetic risk of type 2 diabetes: a case-cohort study
T. Schnurr, Hermina Jakupović, G. Carrasquilla, L. Ängquist +7 more
2020Diabetologia181 citations Open access
Semantic Scholar
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
M. Zillikens, S. Demissie, Y. Hsu, L. Yerges-Armstrong +189 more
2017Nature Communications168 citations Open access
Semantic Scholar
Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels
Y. Mahendran, A. Jonsson, C. Have, K. Allin +6 more
2017Diabetologia142 citations Open access
Semantic Scholar
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
Yun J. Sung, T. Winkler, L. de las Fuentes, Amy R. Bentley +293 more
2018American Journal of Human Genetics134 citations Open access
Semantic Scholar
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Amy R. Bentley, Yun J. Sung, Michael R. Brown, T. Winkler +298 more
2019Nature Genetics122 citations Open access
Semantic Scholar
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions
P. D. de Vries, Michael R. Brown, Amy R. Bentley, Yun J. Sung +262 more
2019112 citations
Semantic Scholar
Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.
A. Kraja, Chun-Yu Liu, J. Fetterman, M. Graff +148 more
2019American Journal of Human Genetics110 citations Open access
Semantic Scholar
Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities
L. O. Huang, A. Rauch, Eugenia Mazzaferro, Michael H. Preuss +12 more
2021Nature Metabolism105 citations
Semantic Scholar
Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity
Olof S. Dallner, Jill M. Marinis, Yi-Hsueh Lu, Kıvanç Birsoy +15 more
2019Nature Medicine102 citations
Semantic Scholar
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
Tuomas O. Kilpeläinen, Amy R. Bentley, R. Noordam, Yun J. Sung +233 more
2019Nature Communications87 citations Open access
Semantic Scholar
Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration
R. Noordam, M. Bos, He-Ming Wang, T. Winkler +144 more
2019Nature Communications76 citations Open access
Semantic Scholar
Genes that make you fat, but keep you healthy
R. Loos, Tuomas O. Kilpeläinen
2018Journal of Internal Medicine59 citations Open access
Semantic Scholar
Polygenic prediction of body mass index and obesity through the life course and across ancestries
R. Smit, K. Wade, Qin Hui, J. Arias +496 more
2025Nature Medicine51 citations Open access
Semantic Scholar
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.
Man Li, Yong Li, Olivia Weeks, Vladan Mijatovic +152 more
2017Journal of the American Society of Nephrology49 citations Open access
Semantic Scholar
Cell-free DNA and RNA - measurement and applications in clinical diagnostics with focus on metabolic disorders.
M. Drag, Tuomas O. Kilpeläinen
2020Physiological Genomics47 citations
Semantic Scholar
The Genetic Basis of Hypertriglyceridemia
G. Carrasquilla, M. Christiansen, Tuomas O. Kilpeläinen
2021Current Atherosclerosis Reports43 citations Open access
Semantic Scholar
A 2 year physical activity and dietary intervention attenuates the increase in insulin resistance in a general population of children: the PANIC study
T. Lakka, N. Lintu, J. Väistö, A. Viitasalo +17 more
2020Diabetologia43 citations Open access
Semantic Scholar
Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis
Jordi Merino, M. Guasch-Ferré, Christina Ellervik, Hassan S. Dashti +64 more
2019British medical journal43 citations Open access
Semantic Scholar
Do gene–environment interactions have implications for the precision prevention of type 2 diabetes?
T. Sørensen, S. Metz, Tuomas O. Kilpeläinen
2022Diabetologia42 citations Open access
Semantic Scholar
Disentangling the genetics of lean mass.
D. Karasik, M. Zillikens, Y. Hsu, A. Aghdassi +153 more
2019American Journal of Clinical Nutrition42 citations Open access
Semantic Scholar
Dairy Consumption and Body Mass Index Among Adults: Mendelian Randomization Analysis of 184802 Individuals from 25 Studies
Tao Huang, M. Ding, H. K. Bergholdt, Tian-Ge Wang +73 more
2017Clinical Chemistry42 citations Open access
Semantic Scholar
Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity
H. Yaghootkar, Yi-Ying Zhang, C. Spracklen, T. Karaderi +112 more
2020Diabetes41 citations Open access
Semantic Scholar
Association of Birth Weight With Type 2 Diabetes and Glycemic Traits
Tao Huang, Tian-Ge Wang, Yan Zheng, C. Ellervik +130 more
2019JAMA Network Open41 citations Open access
Semantic Scholar
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
Yun J. Sung, L. de las Fuentes, T. Winkler, D. Chasman +277 more
2019Human Molecular Genetics39 citations Open access
Semantic Scholar
Estimating causality between smoking and abdominal obesity by Mendelian randomization
G. Carrasquilla, M. Garcia-Ureña, María José Romero Lado, Tuomas O. Kilpeläinen
2023bioRxiv38 citations Open access
Semantic Scholar
NK2R control of energy expenditure and feeding to treat metabolic diseases
F. Sass, Tao Ma, Jeppe H. Ekberg, Melissa A. Kirigiti +43 more
2024Nature36 citations Open access
Semantic Scholar
Evidence of genetic predisposition for metabolically healthy obesity and metabolically obese normal weight.
L. O. Huang, R. Loos, Tuomas O. Kilpeläinen
2018Physiological Genomics36 citations Open access
Semantic Scholar
Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis.
A. Viitasalo, T. Schnurr, N. Pitkänen, Mette Hollensted +19 more
2019American Journal of Clinical Nutrition33 citations Open access
Semantic Scholar
A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria
T. Ahluwalia, Christina-Alexandra Schulz, Johannes Waage, T. Skaaby +25 more
2018Diabetologia31 citations Open access
Semantic Scholar
Longitudinal and cross-sectional associations of adherence to 24-hour movement guidelines with cardiometabolic risk
Marja H. Leppänen, E. Haapala, J. Väistö, U. Ekelund +3 more
2021Scandinavian Journal of Medicine & Science in Sports30 citations Open access
Semantic Scholar
Mendelian randomization suggests a bidirectional, causal relationship between physical inactivity and obesity
G. Carrasquilla, M. Garcia-Ureña, T. Fall, T. Sørensen +1 more
2021bioRxiv29 citations Open access
Semantic Scholar
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.
C. Spracklen, T. Karaderi, H. Yaghootkar, C. Schurmann +100 more
2019American Journal of Human Genetics27 citations Open access
Semantic Scholar
Child-to-adult body size change and risk of type 2 diabetes and cardiovascular disease
G. Carrasquilla, L. Ängquist, T. I. Sørensen, Tuomas O. Kilpeläinen +1 more
2023Diabetologia26 citations Open access
Semantic Scholar
Composite trait Mendelian randomization reveals distinct metabolic and lifestyle consequences of differences in body shape
Jonathan Sulc, A. Sonrel, N. Mounier, C. Auwerx +7 more
2020Communications Biology26 citations Open access
Semantic Scholar
Association of alcohol consumption with allergic disease and asthma: a multicenter Mendelian Randomization analysis
T. Skaaby, Tuomas O. Kilpeläinen, A. E. Taylor, Y. Mahendran +43 more
2018Addiction26 citations Open access
Semantic Scholar
Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions
D. Shungin, W. Deng, T. Varga, J. Luan +26 more
2017PLoS Genetics26 citations Open access
Semantic Scholar
Editorial: Novel Biomarkers for Type 2 Diabetes
T. Ahluwalia, Tuomas O. Kilpeläinen, Sandeep Singh, P. Rossing
2019Frontiers in Endocrinology25 citations Open access
Semantic Scholar
Evidence for shared genetics between physical activity, sedentary behaviour and adiposity‐related traits
T. Schnurr, B. Stallknecht, T. Sørensen, Tuomas O. Kilpeläinen +1 more
2020Obesity Reviews24 citations
Semantic Scholar
Epigenetic rewiring of skeletal muscle enhancers after exercise training supports a role in whole-body function and human health
Kristine Williams, G. Carrasquilla, L. Ingerslev, Mette Yde Hochreuter +7 more
2021Molecular Metabolism23 citations Open access
Semantic Scholar
Dairy Intake and Body Composition and Cardiometabolic Traits among Adults: Mendelian Randomization Analysis of 182041 Individuals from 18 Studies
Tao Huang, Dianjianyi Sun, Yoriko Heianza, H. K. M. Bergholdt +52 more
2019Clinical Chemistry23 citations Open access
Semantic Scholar
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci
L. de las Fuentes, Yun J. Sung, R. Noordam, T. Winkler +218 more
2020Molecular Psychiatry22 citations Open access
Semantic Scholar
Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure
He-Ming Wang, R. Noordam, B. Cade, K. Schwander +121 more
2020bioRxiv22 citations Open access
Semantic Scholar
A genetic association study of circulating coagulation Factor VIII and von Willebrand Factor levels.
P. D. de Vries, Paula Reventun, Michael R. Brown, Adam S. Heath +91 more
2024Blood20 citations Open access
Semantic Scholar
Mendelian randomization suggests a bidirectional, causal relationship between physical inactivity and adiposity
G. Carrasquilla, M. Garcia-Ureña, Tove Fall, T. I. Sørensen +1 more
2022eLife18 citations Open access
Semantic Scholar
The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study
Aino-Maija Eloranta, T. Sallinen, A. Viitasalo, N. Lintu +18 more
2020European Journal of Nutrition18 citations Open access
Semantic Scholar
Raman imaging of amorphous-amorphous phase separation in small molecule co-amorphous systems.
Tuomas O. Kilpeläinen, K. Pajula, T. Ervasti, E. Uurasjärvi +2 more
2020European journal of pharmaceutics and biopharmaceutics17 citations Open access
Semantic Scholar
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Nicole Fadahunsi, Jonas Petersen, Sophia Metz, Alexander Jakobsen +18 more
2024Science Advances16 citations Open access
Semantic Scholar
Abdominal obesity genetic variants predict waist circumference regain after weight loss.
M. Christiansen, Tuomas O. Kilpeläinen, J. McCaffery
2023Diabetes15 citations Open access
Semantic Scholar

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