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D. M. Walker · SciRah

Researcher profile · Semantic Scholar

D. M. Walker

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D. M. Walker — researcher profile on SciRah

h-index: 18
Works: 45
Citations: 965

Most-cited papers

Perinatal genotoxicity and carcinogenicity of anti-retroviral nucleoside analog drugs.
M. Poirier, O. Olivero, D. M. Walker, V. Walker
2004Toxicology and Applied Pharmacology121 citations
Semantic Scholar
Zidovudine-didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells.
Q. Meng, D. M. Walker, O. Olivero, Xiao-Chu Shi +3 more
2000Proceedings of the National Academy of Sciences of the United States of America73 citations Open access
Semantic Scholar
Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother–child pairs to AZT or AZT‐3TC
P. Escobar, O. Olivero, N. Wade, E. Abrams +10 more
2007Environmental and Molecular Mutagenesis54 citations
Semantic Scholar
Mechanistic Basis for Nonlinear Dose-Response Relationships for Low-Dose Radiation-Induced Stochastic Effects
B. Scott, D. M. Walker, Y. Tesfaigzi, H. Schöllnberger +1 more
2003Nonlinearity in Biology, toxicology, medicine53 citations Open access
Semantic Scholar
Culture and propagation of Hprt mutant T‐lymphocytes isolated from mouse spleen
Q. Meng, Thomas R. Skopek, D. M. Walker, Shellene Hurley‐Leslie +3 more
1998Environmental and Molecular Mutagenesis47 citations
Semantic Scholar
Intraperitoneal administration of coumarin causes tissue-selective depletion of cytochromes P450 and cytotoxicity in the olfactory mucosa.
Jun Gu, V. E. Walker, T. Lipinskas, D. M. Walker +1 more
1997Toxicology and Applied Pharmacology47 citations
Semantic Scholar
Mutagenicity of zidovudine, lamivudine, and abacavir following in vitro exposure of human lymphoblastoid cells or in utero exposure of CD‐1 mice to single agents or drug combinations
S. Torres, D. M. Walker, Meghan M. Carter, Dennis L. Cook +5 more
2007Environmental and Molecular Mutagenesis46 citations
Semantic Scholar
Relationships between exposure, cell loss and proliferation, and manifestation of Hprt mutant T cells following treatment of preweanling, weanling, and adult male mice with N-ethyl-N-nitrosourea.
V. E. Walker, Irene M. Jones, Tawni L. Crippen, Q. Meng +7 more
1999Mutation research39 citations
Semantic Scholar
Transplacental carcinogenicity of 3′‐azido‐3′‐deoxythymidine in B6C3F1 mice and F344 rats
D. M. Walker, D. Malarkey, S. Seilkop, Frederick A. Ruecker +7 more
2007Environmental and Molecular Mutagenesis36 citations
Semantic Scholar
Persistence of mitochondrial toxicity in hearts of female B6C3F1 mice exposed in utero to 3′-azido-3′-deoxythymidine
D. M. Walker, M. Poirier, M. Campen, Dennis L. Cook +6 more
2007Cardiovascular Toxicology36 citations
Semantic Scholar
Detection of cyclophosphamide‐induced mutations at the Hprt but not the lacI locus in splenic lymphocytes of exposed mice
V. E. Walker, Julie L. Andrews, P. B. Upton, Thomas R. Skopek +5 more
1999Environmental and Molecular Mutagenesis36 citations
Semantic Scholar
Mutagenicity of 1,3-butadiene at the Hprt locus of T-lymphocytes following inhalation exposures of female mice and rats.
Q. Meng, R. F. Henderson, Tao Chen, R. Heflich +4 more
1999Mutation research35 citations
Semantic Scholar
Mutagenicity of the racemic mixtures of butadiene monoepoxide and butadiene diepoxide at the Hprt locus of T-lymphocytes following inhalation exposures of female mice and rats.
Q. Meng, R. Henderson, D. M. Walker, M. Bauer +2 more
1999Mutation research29 citations
Semantic Scholar
Relative mutagenic potencies of several nucleoside analogs, alone or in drug pairs, at the HPRT and TK loci of human TK6 lymphoblastoid cells
Meghan M. Carter, S. Torres, Dennis L. Cook, Consuelo L. McCash +3 more
2007Environmental and Molecular Mutagenesis28 citations
Semantic Scholar
Mutagenicity of stereochemical configurations of 1,2-epoxybutene and 1,2:3,4-diepoxybutane in human lymphblastoid cells.
Q. Meng, Diana L. Redetzke, Linda C. Hackfeld, R. P. Hodge +2 more
2007Chemico-Biological Interactions27 citations
Semantic Scholar
Age-, gender-, and species-dependent mutagenicity in T cells of mice and rats exposed by inhalation to 1,3-butadiene.
Q. Meng, D. M. Walker, J. McDonald, R. Henderson +11 more
2007Chemico-Biological Interactions27 citations
Semantic Scholar
Characterization of Hprt mutations in cDNA and genomic DNA of T‐cell mutants from control and 1,3‐butadiene‐exposed male B6C3F1 mice and F344 rats
Q. Meng, D. M. Walker, B. Scott, S. Seilkop +2 more
2004Environmental and Molecular Mutagenesis24 citations
Semantic Scholar
Plasma and cellular markers of 3′‐azido‐3′‐dideoxythymidine (AZT) metabolism as indicators of DNA damage in cord blood mononuclear cells from infants receiving prepartum NRTIs
Q. Meng, O. Olivero, M. Fasco, R. Bellisario +11 more
2007Environmental and Molecular Mutagenesis22 citations
Semantic Scholar
Mutagenicity at the Hprt locus in T cells of female mice following inhalation exposures to low levels of 1,3-butadiene.
Q. Meng, R. F. Henderson, Li Long, Lee F. Blair +4 more
2001Chemico-Biological Interactions19 citations
Semantic Scholar
Genotoxicity of 1,3-butadiene and its epoxy intermediates.
V. Walker, D. M. Walker, Q. Meng, J. McDonald +7 more
2009Research report17 citations
Semantic Scholar
Low-Dose Radiation and Genotoxic Chemicals Can Protect against Stochastic Biological Effects
B. Scott, D. M. Walker, V. Walker
2004Nonlinearity in Biology, toxicology, medicine16 citations Open access
Semantic Scholar
In Utero Exposure of Female CD-1 Mice to AZT and/or 3TC: II. Persistence of Functional Alterations in Cardiac Tissue
S. Torres, R. Divi, D. M. Walker, Consuelo L. McCash +8 more
2010Cardiovascular Toxicology15 citations Open access
Semantic Scholar
In Utero Exposure of Female CD-1 Mice to AZT and/or 3TC: I. Persistence of Microscopic Lesions in Cardiac Tissue
S. Torres, T. March, Meghan M. Carter, Consuelo L. McCash +4 more
2010Cardiovascular Toxicology14 citations Open access
Semantic Scholar
WR1065 Mitigates AZT-ddI-Induced Mutagenesis and Inhibits Viral Replication
D. M. Walker, A. Kajon, S. Torres, Meghan M. Carter +8 more
2009Environmental and Molecular Mutagenesis14 citations Open access
Semantic Scholar
Analysis of Biomarkers of DNA Damage and Mutagenicity in Mice Exposed to Acrylonitrile
V. Walker, D. M. Walker, B. Ghanayem, G. Douglas
2020Chemical Research in Toxicology13 citations Open access
Semantic Scholar
Mutational Analysis of the Mitochondrial tRNA Genes and Flanking Regions in Umbilical Cord Tissue from Uninfected Infants Receiving AZT-Based Therapies for Prophylaxis of HIV-1
S. Torres, D. M. Walker, Consuelo L. McCash, Meghan M. Carter +7 more
2009Environmental and Molecular Mutagenesis13 citations Open access
Semantic Scholar
Frequencies of micronucleated reticulocytes, a dosimeter of DNA double-strand breaks, in infants receiving computed tomography or cardiac catheterization.
Mona Khattab, D. M. Walker, R. Albertini, J. Nicklas +3 more
2017Mutation research12 citations
Semantic Scholar
1,3-Butadiene metabolite 1,2,3,4 diepoxybutane induces DNA adducts and micronuclei but not t(9;22) translocations in human cells.
V. Walker, Amanda Degner, Elizabeth W. Carter, J. Nicklas +3 more
2019Chemico-Biological Interactions10 citations Open access
Semantic Scholar
Frequent Mitochondrial DNA Mutations and Polymorphisms in Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia.
S. Lipshultz, V. Walker, S. Torres, D. M. Walker +4 more
200710 citations
Semantic Scholar
Analysis of DNA Adducts and Mutagenic Potency and Specificity in Rats Exposed to Acrylonitrile.
V. Walker, T. Fennell, D. M. Walker, M. Bauer +3 more
2020Chemical Research in Toxicology9 citations
Semantic Scholar
Hprt mutant frequencies in splenic T‐cells of male F344 rats exposed by inhalation to propylene
D. M. Walker, S. Seilkop, B. Scott, V. Walker
2004Environmental and Molecular Mutagenesis8 citations Open access
Semantic Scholar
The stress response resolution assay. II. Quantitative assessment of environmental agent/condition effects on cellular stress resolution outcomes in epithelium
D. M. Walker, J. Nicklas, V. E. Walker
2013Environmental and Molecular Mutagenesis6 citations
Semantic Scholar
The stress response resolution assay. I. Quantitative assessment of environmental agent/condition effects on cellular stress resolution outcomes in epithelium
D. M. Walker, J. O'Neill, F. Tyson, V. E. Walker
2013Environmental and Molecular Mutagenesis6 citations
Semantic Scholar
Measurement of plasma or urinary metabolites and Hprt mutant frequencies following inhalation exposure of mice and rats to 3-butene-1,2-diol.
D. M. Walker, J. McDonald, Q. Meng, D. Kracko +5 more
2007Chemico-Biological Interactions3 citations
Semantic Scholar
Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo
M. Poirier, O. Olivero, Andrew W. Hardy, G. Franchini +4 more
2009AIDS Research and Therapy2 citations Open access
Semantic Scholar
Mutational analysis of the mitochondrial tRNA genes and flanking regions in lymphocytes from long-term pediatric cancer survivors given doxorubicin chemotherapy for acute lymphoblastic leukemia
V. E. Walker, Neha Bansal, S. Torres, Kristen E. Stevenson +4 more
2025Cardio-Oncology1 citations Open access
Semantic Scholar
WR1065 conjugated to thiol-PEG polymers as novel anticancer prodrugs: broad spectrum efficacy, synergism, and drug resistance reversal
D. M. Walker, T. Lazarova, S. Riesinger, M. Poirier +3 more
2023Frontiers in Oncology1 citations Open access
Semantic Scholar
Clonality, trafficking, and molecular alterations among Hprt mutant T lymphocytes isolated from control mice versus mice treated with N-ethyl-N-nitrosourea
Stephen A. Judice, H. Sussman, D. M. Walker, J. O'Neill +2 more
2023Environmental and Molecular Mutagenesis1 citations Open access
Semantic Scholar
Transplacental Exposure to Antiretroviral Drugs and Cardiotoxicity in Offspring
S. Torres, D. M. Walker, R. Divi, M. Poirier +1 more
20101 citations
Semantic Scholar
Trp53 Deficiency Increases the Frequency of Hprt Mutant T Lymphocytes Following High‐LET Iron Particle Irradiation of Mice
V. Walker, D. M. Walker, V. N. Dobrovolsky, L. Lutze-Mann
2026Environmental and Molecular Mutagenesis0 citations Open access
Semantic Scholar
Sequence variants in mitochondrial tRNA genes and flanking regions compared to cardiovascular status in CHAART-2 children
V. E. Walker, S. Torres, D. M. Walker, P. Vacek +1 more
2026Progress in pediatric cardiology0 citations
Semantic Scholar
DGGE analysis of mitochondrial tRNA gene and p53 gene mutations in newborns receiving prepartum AZT-based HIV-1 prophylaxis
S. Torres, Dennis L. Cook, Consuelo L. McCash, D. M. Walker +1 more
20070 citations
Semantic Scholar
Antiretrovirale mittel aus organischem disulfiden
D. M. Walker, V. E. Walker, M. Poirier, G. Shearer
20070 citations
Semantic Scholar
Antiretroviral activity of aminothiols, WR2721 and WR1065
M. Poirier, G. Shearer, Andrew W. Hardy, O. Olivero +2 more
2006Retrovirology0 citations Open access
Semantic Scholar
FINAL REPORT U. S. Department of Energy ADVANCED COMPUTATIONAL APPROACHES TO CHARACTERIZING STOCHASTIC CELLULAR RESPONSES TO LOW-DOSE, LOW-DOSE-RATE EXPOSURES
P. Gerde, Y. Tesfagzi, D. M. Walker, T. Hanson +4 more
20030 citations
Semantic Scholar

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V. Walker — researcher profile on SciRah
V. E. Walker×15
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Q. Meng×13
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