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J. Schreiber · SciRah

Researcher profile · Semantic Scholar

J. Schreiber

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J. Schreiber — researcher profile on SciRah

h-index: 12
Works: 44
Citations: 404

Most-cited papers

Beyond Hot and Spicy: TRPV Channels and their Pharmacological Modulation.
G. Seebohm, J. Schreiber
2021Cellular Physiology and Biochemistry50 citations Open access
Semantic Scholar
A common mechanism allows selective targeting of GluN2B subunit-containing N-methyl-D-aspartate receptors
J. Schreiber, D. Schepmann, Bastian Frehland, S. Thum +6 more
2019Communications Biology31 citations Open access
Semantic Scholar
The ubiquitination landscape of the influenza A virus polymerase
Franziska Günl, T. Krischuns, J. Schreiber, Lea Henschel +9 more
2022Nature Communications28 citations Open access
Semantic Scholar
Ifenprodil Stereoisomers: Synthesis, Absolute Configuration, and Correlation with Biological Activity.
E. Bechthold, J. Schreiber, K. Lehmkuhl, Bastian Frehland +8 more
2021Journal of Medicinal Chemistry27 citations Open access
Semantic Scholar
K2P18.1 translates T cell receptor signals into thymic regulatory T cell development
T. Ruck, S. Bock, S. Pfeuffer, C. Schroeter +34 more
2021Cell Research26 citations Open access
Semantic Scholar
Design, Synthesis, Pharmacological Evaluation and Docking Studies of GluN2B‐Selective NMDA Receptor Antagonists with a Benzo[7]annulen‐7‐amine Scaffold
Sandeep Gawaskar, Louisa Temme, J. Schreiber, D. Schepmann +6 more
2017ChemMedChem25 citations
Semantic Scholar
Synthesis and Pharmacological Evaluation of Enantiomerically Pure GluN2B Selective NMDA Receptor Antagonists
Frederik Börgel, Marina Szermerski, J. Schreiber, Louisa Temme +7 more
2018ChemMedChem23 citations
Semantic Scholar
Comparative Pharmacological Study of Common NMDA Receptor Open Channel Blockers Regarding Their Affinity and Functional Activity toward GluN2A and GluN2B NMDA Receptors
Louisa Temme, D. Schepmann, J. Schreiber, Bastian Frehland +1 more
2018ChemMedChem23 citations
Semantic Scholar
Deconstruction - reconstruction approach to analyze the essential structural elements of tetrahydro-3-benzazepine-based antagonists of GluN2B subunit containing NMDA receptors.
Sougata Dey, Louisa Temme, J. Schreiber, D. Schepmann +5 more
2017European journal of medicinal chemistry17 citations Open access
Semantic Scholar
The Special One: Architecture, Physiology and Pharmacology of the TRESK Channel.
J. Schreiber, M. Düfer, G. Seebohm
2022Cellular Physiology and Biochemistry14 citations Open access
Semantic Scholar
Effects of Axonal Demyelination, Inflammatory Cytokines and Divalent Cation Chelators on Thalamic HCN Channels and Oscillatory Bursting
T. Oniani, Laura Vinnenberg, Rahul Chaudhary, J. Schreiber +10 more
2022International Journal of Molecular Sciences13 citations Open access
Semantic Scholar
Systematic variation of the benzenesulfonamide part of the GluN2A selective NMDA receptor antagonist TCN-201.
Sebastian L. Müller, J. Schreiber, D. Schepmann, N. Strutz‐Seebohm +2 more
2017European journal of medicinal chemistry13 citations Open access
Semantic Scholar
A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncoupling
J. Schreiber, Melina Möller, M. Zaydman, Lu Zhao +15 more
2022Communications Biology12 citations Open access
Semantic Scholar
Systematic variation of the benzoylhydrazine moiety of the GluN2A selective NMDA receptor antagonist TCN-201.
J. Schreiber, Sebastian L. Müller, Stefanie E. Westphälinger, D. Schepmann +3 more
2018European journal of medicinal chemistry10 citations
Semantic Scholar
Indazole as a Phenol Bioisostere: Structure-Affinity Relationships of GluN2B-Selective NMDA Receptor Antagonists.
Judith Lüken, Gunnar Goerges, Nadine Ritter, Paul Disse +6 more
2023Journal of Medicinal Chemistry9 citations Open access
Semantic Scholar
Synthesis of tropane-based σ1 receptor antagonists with antiallodynic activity.
E. Bechthold, J. Schreiber, Nadine Ritter, Lucie Grey +6 more
2022European journal of medicinal chemistry8 citations Open access
Semantic Scholar
Cardiac K+ Channels and Channelopathies.
J. Schreiber, G. Seebohm
2021Handbook of Experimental Pharmacology8 citations
Semantic Scholar
Negative allosteric modulators of the GluN2B NMDA receptor with phenylethylamine structure embedded in ring-expanded and ring-contracted scaffolds.
Louisa Temme, E. Bechthold, J. Schreiber, Sandeep Gawaskar +5 more
2020European journal of medicinal chemistry8 citations Open access
Semantic Scholar
Rottlerin: Structure Modifications and KCNQ1/KCNE1 Ion Channel Activity
Marco Lübke, J. Schreiber, Thắng Lê Quốc, F. Körber +7 more
2020ChemMedChem6 citations Open access
Semantic Scholar
An Assay to Determine Mechanisms of Rapid Autoantibody-Induced Neurotransmitter Receptor Endocytosis and Vesicular Trafficking in Autoimmune Encephalitis
E. Amedonu, C. Brenker, S. Barman, J. Schreiber +14 more
2019Frontiers in Neurology6 citations Open access
Semantic Scholar
Cloxyquin activates hTRESK by allosteric modulation of the selectivity filter
J. Schreiber, A. Derksen, Gunnar Goerges, Sven Schütte +7 more
2023Communications Biology5 citations Open access
Semantic Scholar
Synthesis of GluN2A-selective NMDA receptor antagonists with an electron-rich aromatic B-ring.
Remya Rajan, D. Schepmann, J. Schreiber, G. Seebohm +1 more
2020European journal of medicinal chemistry5 citations
Semantic Scholar
4,4'-Diisothiocyanato-2,2'-Stilbenedisulfonic Acid (DIDS) Modulates the Activity of KCNQ1/KCNE1 Channels by an Interaction with the Central Pore Region.
E. Bollmann, J. Schreiber, Nadine Ritter, S. Peischard +7 more
2020Cellular Physiology and Biochemistry4 citations Open access
Semantic Scholar
Deconstruction - Reconstruction: Analysis of the Crucial Structural Elements of GluN2B-Selective, Negative Allosteric NMDA Receptor Modulators with 3-Benzazepine Scaffold.
Nadine Ritter, Marvin Korff, Alexander Markus, D. Schepmann +3 more
2020Cellular Physiology and Biochemistry4 citations Open access
Semantic Scholar
Phenol—Benzoxazolone bioisosteres: Synthesis and biological evaluation of tricyclic GluN2B‐selective N‐methyl‐ d‐aspartate receptor antagonists
Alexander Markus, J. Schreiber, Gunnar Goerges, Bastian Frehland +3 more
2022Archiv der Pharmazie3 citations Open access
Semantic Scholar
Phenol‐benzoxazolone bioisosteres of GluN2B‐NMDA receptor antagonists: Unexpected rearrangement during reductive alkylation with phenylcyclohexanone
Alexander Markus, J. Schreiber, Gunnar Goerges, Bastian Frehland +5 more
2022Archiv der Pharmazie3 citations Open access
Semantic Scholar
Chemical, pharmacodynamic and pharmacokinetic characterization of the GluN2B receptor antagonist 3-(4-phenylbutyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-1,7-diol – starting point for PET tracer development
Marvin Korff, Ruben Steigerwald, E. Bechthold, D. Schepmann +4 more
2022Biological chemistry3 citations
Semantic Scholar
[2.2]Paracyclophane‐Based TCN‐201 Analogs as GluN2A‐Selective NMDA Receptor Antagonists
Remya Rajan, D. Schepmann, Ruben Steigerwald, J. Schreiber +4 more
2021ChemMedChem3 citations Open access
Semantic Scholar
Structure-Function Relationships of K2P Channels.
J. Schreiber, G. Seebohm
2026Advances in Experimental Medicine and Biology2 citations
Semantic Scholar
Stereoselective Synthesis of Conformationally Restricted γ- and β-Amino Alcohols as GluN2B Subtype-Selective NMDA Receptor Antagonists.
Marvin Korff, Gunnar Goerges, Judith Schmidt, D. Schepmann +3 more
2025Journal of Medicinal Chemistry2 citations
Semantic Scholar
Evaluation of SK-N-SH Cells as a Model for NMDA Receptor Induced Toxicity.
Gunnar Goerges, Paul Disse, S. Peischard, Nadine Ritter +4 more
2024Cellular Physiology and Biochemistry2 citations Open access
Semantic Scholar
Enantiomerically Pure Indazole Bioisosteres of Ifenprodil and Ro 25-6981 as Negative Allosteric Modulators of NMDA Receptors with the GluN2B Subunit.
Judith Lüken, Gunnar Goerges, J. Schreiber, Judith Schmidt +4 more
2024Journal of Medicinal Chemistry2 citations Open access
Semantic Scholar
Downstream Allosteric Modulation of NMDA Receptors by 3-Benzazepine Derivatives
Nadine Ritter, Paul Disse, Isabel Aymanns, Lena Mücher +9 more
2023Molecular Neurobiology2 citations Open access
Semantic Scholar
The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state transition
Maurice Dellin, Ina Rohrbeck, Purva Asrani, J. Schreiber +16 more
2023Biological chemistry2 citations
Semantic Scholar
TMPRSS6 cleaves KCNE1 and causes arrhythmias in iron overload disease
S. Peischard, Philipp Kastl, Gunnar Goerges, J. Schreiber +16 more
2024bioRxiv1 citations Open access
Semantic Scholar
A novel fluorescent labeling compound for GluN2A containing N-methyl-d-aspartate receptors identified by autodisplay-based screening
Alexander Dombovski, Ruben Steigerwald, Nadine Ritter, Paul Disse +9 more
2024Journal of Pharmaceutical Analysis1 citations Open access
Semantic Scholar
Negative allosteric modulators of NMDA receptors with GluN2B subunit: synthesis of β-aminoalcohols by epoxide opening and subsequent rearrangement.
Marvin Korff, Judith Lüken, Judith Schmidt, D. Schepmann +6 more
2023Organic and biomolecular chemistry1 citations
Semantic Scholar
Synthesis and biological evaluation of conformationally restricted GluN2B ligands derived from eliprodil.
E. Bechthold, J. Schreiber, Nadine Ritter, D. Schepmann +3 more
2022European journal of medicinal chemistry1 citations Open access
Semantic Scholar
Can Unlikely Neanderthal Chloride Channel CLC-2 Gene Variants Provide Insights in Modern Human Infertility?
Elena Jeworutzki, F. Tüttelmann, Ina Rothenberg, M. Pusch +5 more
2021Cellular Physiology and Biochemistry1 citations Open access
Semantic Scholar
Evaluation of Novel Cloxyquin Analogs for K2P18.1 Channel Modulation
Jasmin Sörgel, Marcela Kloth, Henning Klaasen, S. Meuth +3 more
2026Archiv der Pharmazie0 citations Open access
Semantic Scholar
A sequence variation between two orthologues alters functional expression of the potassium channel Kesv of Ectocarpus siliculosus virus
Purva Asrani, Aladdin Elgendy, André P. Zeipelt, Gunnar Goerges +7 more
2026bioRxiv0 citations Open access
Semantic Scholar
Negative allosteric modulation of NMDA receptors with GluN2B subunit: synthesis of γ-amino alcohols embedded in a 1-benzoxepine scaffold
Felicitas Wendling, Yuan Chang-Halabi, Judith Schmidt, D. Schepmann +4 more
2026RSC Medicinal Chemistry0 citations Open access
Semantic Scholar
An Activator Locks Kv7.1 Channels Open by Electro-Mechanical Uncoupling and Allosterically Modulates its Pore
Melina Möller, J. Schreiber, M. Zaydman, Zachary W. Beller +10 more
2021bioRxiv0 citations Open access
Semantic Scholar
K2P18.1 translates T cell receptor signals into thymic regulatory T cell development
T. Ruck, S. Bock, S. Pfeuffer, C. Schroeter +34 more
2021Cell Research0 citations Open access
Semantic Scholar

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B. Wünsch×32
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