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H. Lijnen · SciRah

Researcher profile · Semantic Scholar

H. Lijnen

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H. Lijnen — researcher profile on SciRah

h-index: 43
Works: 138
Citations: 6,722

Most-cited papers

Plasmin and Matrix Metalloproteinases in Vascular Remodeling
H. Lijnen
2001Thrombosis and Haemostasis494 citations
Semantic Scholar
Pleiotropic functions of plasminogen activator inhibitor‐1
H. Lijnen
2005Journal of Thrombosis and Haemostasis322 citations Open access
Semantic Scholar
Modulation of adipose tissue expression of murine matrix metalloproteinases and their tissue inhibitors with obesity.
E. Maquoi, C. Munaut, A. Colige, D. Collen +1 more
2002Diabetes285 citations Open access
Semantic Scholar
Elements of the Fibrinolytic System
H. Lijnen
2001Annals of the New York Academy of Sciences260 citations
Semantic Scholar
Function of the plasminogen/plasmin and matrix metalloproteinase systems after vascular injury in mice with targeted inactivation of fibrinolytic system genes.
H. Lijnen, B. van Hoef, F. Lupu, L. Moons +2 more
1998Arteriosclerosis, Thrombosis and Vascular Biology246 citations Open access
Semantic Scholar
Modulation of angiogenesis during adipose tissue development in murine models of obesity.
G. Voros, E. Maquoi, D. Demeulemeester, Natalie Clerx +2 more
2005Endocrinology229 citations Open access
Semantic Scholar
Angiogenesis and obesity.
H. Lijnen
2008Cardiovascular Research207 citations Open access
Semantic Scholar
Elastin fragmentation in atherosclerotic mice leads to intraplaque neovascularization, plaque rupture, myocardial infarction, stroke, and sudden death
C. Van der Donckt, J. V. Van Herck, D. Schrijvers, G. Vanhoutte +16 more
2014European Heart Journal175 citations Open access
Semantic Scholar
Evaluation of Matrix Metalloproteinases in Atherosclerosis Using a Novel Noninvasive Imaging Approach
E. Lancelot, Vardan Amirbekian, I. Brigger, J. Raynaud +16 more
2008Arteriosclerosis, Thrombosis and Vascular Biology151 citations Open access
Semantic Scholar
Matrix Metalloproteinase Inhibition Impairs Adipose Tissue Development in Mice
H. Lijnen, E. Maquoi, L. B. Hansen, B. van Hoef +2 more
2002Arteriosclerosis, Thrombosis and Vascular Biology135 citations Open access
Semantic Scholar
Matrix Metalloproteinase System Deficiencies and Matrix Degradation
H. Lijnen, D. Collen
1999Thrombosis and Haemostasis134 citations
Semantic Scholar
Glucocorticoids and insulin promote plasminogen activator inhibitor 1 production by human adipose tissue.
P. Morange, J. Aubert, F. Peiretti, H. Lijnen +5 more
1999Diabetes120 citations
Semantic Scholar
Vitronectin concentrates proteolytic activity on the cell surface and extracellular matrix by trapping soluble urokinase receptor-urokinase complexes.
T. Chavakis, S. M. Kanse, Barbara Yutzy, H. Lijnen +1 more
1998Blood105 citations Open access
Semantic Scholar
Metalloproteinases in Development and Progression of Vascular Disease
H. Lijnen
2003Pathophysiology of Haemostasis and Thrombosis101 citations
Semantic Scholar
Fibrinolytic cross-talk: a new mechanism for plasmin formation.
T. Dejouvencel, Loïc Doeuvre, R. Lacroix, L. Plawinski +3 more
2010Blood98 citations Open access
Semantic Scholar
Tumor Necrosis Factor-α and Angiostatin Are Mediators of Endothelial Cytotoxicity in Bronchoalveolar Lavages of Patients with Acute Respiratory Distress Syndrome
J. Hamacher, R. Lucas, H. Lijnen, Susanne Buschke +5 more
200295 citations
Semantic Scholar
Tissue inhibitor of matrix metalloproteinases-1 impairs arterial neointima formation after vascular injury in mice.
H. Lijnen, P. D. Soloway, D. Collen
1999Circulation Research87 citations Open access
Semantic Scholar
Issue Editorial Focus : Issue Editorial Focus
D. Collen, H. Lijnen
200586 citations
Semantic Scholar
Enhanced nutritionally induced adipose tissue development in mice with stromelysin-1 gene inactivation
E. Maquoi, D. Demeulemeester, Gábor Vörös, D. Collen +1 more
2003Thrombosis and Haemostasis79 citations Open access
Semantic Scholar
Mice Deficient in the Respiratory Chain Gene Cox6a2 Are Protected against High-Fat Diet-Induced Obesity and Insulin Resistance
R. Quintens, Sarvjeet Singh, K. Lemaire, K. de Bock +18 more
2013PLoS ONE73 citations Open access
Semantic Scholar
Extracellular proteolysis in the development and progression of atherosclerosis.
H. Lijnen
2001Biochemical Society Transactions73 citations
Semantic Scholar
Adipose Tissue Expression of Gelatinases in Mouse Models of Obesity
H. Lijnen, E. Maquoi, P. Holvoet, A. Mertens +4 more
2001Thrombosis and Haemostasis70 citations Open access
Semantic Scholar
Temporal and Topographic Matrix Metalloproteinase Expression after Vascular Injury in Mice
H. Lijnen, F. Lupu, L. Moons, P. Carmeliet +2 more
1999Thrombosis and Haemostasis67 citations
Semantic Scholar
Impaired adipose tissue development in mice with inactivation of placental growth factor function.
H. Lijnen, V. Christiaens, Ilse Scroyen, G. Voros +3 more
2006Diabetes66 citations Open access
Semantic Scholar
Vascular release of plasminogen activator inhibitor-1 impairs fibrinolysis during acute arterial thrombosis in mice.
Tomihisa Kawasaki, M. Dewerchin, H. Lijnen, Jos Vermylen +1 more
2000Blood65 citations
Semantic Scholar
What has been learned about the cardiovascular effects of matrix metalloproteinases from mouse models?
S. Janssens, H. Lijnen
2006Cardiovascular Research62 citations
Semantic Scholar
Adipocyte Hypertrophy in Stromelysin-3 Deficient Mice with Nutritionally Induced Obesity
H. Lijnen, B. van Hoef, L. Frederix, M. Rio +1 more
2002Thrombosis and Haemostasis60 citations
Semantic Scholar
Accelerated neointima formation after vascular injury in mice with stromelysin-3 (MMP-11) gene inactivation.
H. Lijnen, B. van Hoef, Ingrid Vanlinthout, M. Verstreken +2 more
1999Arteriosclerosis, Thrombosis and Vascular Biology60 citations Open access
Semantic Scholar
Modulation of Fibrinolytic and Gelatinolytic Activity during Adipose Tissue Development in a Mouse Model of Nutritionally Induced Obesity
H. Lijnen, E. Maquoi, D. Demeulemeester, B. van Hoef +1 more
2002Thrombosis and Haemostasis57 citations Open access
Semantic Scholar
Role of fibrinolysis in obesity and thrombosis.
H. Lijnen
2009Thrombosis Research56 citations
Semantic Scholar
Stromelysin-1 (MMP-3)-independent gelatinase expression and activation in mice.
H. Lijnen, J. Silence, B. van Hoef, D. Collen
1998Blood53 citations
Semantic Scholar
Role of proteolysis in development of murine adipose tissue
V. Christiaens, Ilse Scroyen, H. Lijnen
2008Thrombosis and Haemostasis49 citations
Semantic Scholar
Plasminogen activation: a mediator of vascular smooth muscle cell apoptosis in atherosclerotic plaques
P. Rossignol, A. Luttun, J. Martín-Ventura, F. Lupu +4 more
2006Journal of Thrombosis and Haemostasis46 citations Open access
Semantic Scholar
Tumor necrosis factor-alpha and angiostatin are mediators of endothelial cytotoxicity in bronchoalveolar lavages of patients with acute respiratory distress syndrome.
J. Hamacher, R. Lucas, H. Lijnen, Susanne Buschke +5 more
2002American Journal of Respiratory and Critical Care Medicine44 citations
Semantic Scholar
Fumagillin Reduces Adipose Tissue Formation in Murine Models of Nutritionally Induced Obesity
H. Lijnen, L. Frederix, B. van Hoef
2010Obesity43 citations
Semantic Scholar
Progression of the Prothrombotic State in Aging Bmal1-Deficient Mice
Bianca Hemmeryckx, C. V. Van Hove, P. Fransen, J. Emmerechts +4 more
2011Arteriosclerosis, Thrombosis and Vascular Biology37 citations Open access
Semantic Scholar
Impact of Clock Gene Bmal1 Deficiency on Nutritionally Induced Obesity in Mice
Bianca Hemmeryckx, U. Himmelreich, M. Hoylaerts, H. Lijnen
2011Obesity37 citations
Semantic Scholar
Generation of a Stable Activated Thrombin Activable Fibrinolysis Inhibitor Variant*
Erik Ceresa, Kirsten Van de Borne, M. Peeters, H. Lijnen +2 more
2006Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Deleterious effects of lack of cardiac PAI-1 after coronary occlusion in mice and their pathophysiologic determinants
A. T. Tarikuz Zaman, S. Fujii, D. Schneider, D. Taatjes +2 more
2007Histochemistry and Cell Biology33 citations
Semantic Scholar
Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin‐induced cell detachment and apoptosis
B. Ho-Tin-Noé, Gertrudis Rojas, R. Vranckx, H. Lijnen +1 more
2005The FEBS Journal33 citations
Semantic Scholar
Gelatinase B (MMP-9) deficiency does not affect murine adipose tissue development
M. Van Hul, Heléne Piccard, H. Lijnen
2010Thrombosis and Haemostasis30 citations
Semantic Scholar
Effect of tissue inhibitor of matrix metalloproteinases-1 on in vitro and in vivo adipocyte differentiation.
Ilse Scroyen, Leentje Cosemans, H. Lijnen
2009Thrombosis Research28 citations
Semantic Scholar
Overexpression of tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in mice does not affect adipogenesis or adipose tissue development
D. Demeulemeester, Ilse Scroyen, G. Voros, J. Snoeys +3 more
2006Thrombosis and Haemostasis27 citations
Semantic Scholar
Tiplaxtinin impairs nutritionally induced obesity in mice
H. Lijnen, M. Alessi, L. Frederix, D. Collen +1 more
2006Thrombosis and Haemostasis26 citations
Semantic Scholar
Plasminogen activator inhibitor-1 impairs plasminogen activationmediated vascular smooth muscle cell apoptosis
P. Rossignol, E. Anglés-Cano, H. Lijnen
2006Thrombosis and Haemostasis25 citations Open access
Semantic Scholar
From mice to men – mouse models in obesity research: What can we learn?
Ilse Scroyen, Bianca Hemmeryckx, H. Lijnen
2013Thrombosis and Haemostasis23 citations
Semantic Scholar
ADAMTS5 deficiency protects against non‐alcoholic steatohepatitis in obesity
D. Bauters, Pieter Spincemaille, L. Geys, D. Cassiman +4 more
2016Liver international (Print)21 citations
Semantic Scholar
Stromelysin-2 (MMP-10) deficiency does not affect adipose tissue formation in a mouse model of nutritionally induced obesity.
H. Lijnen, B. van Hoef, J. Rodríguez, J. Páramo
2009Biochemical and Biophysical Research Communications - BBRC20 citations
Semantic Scholar
Does rosiglitazone affect adiposity and cardiac function in genetic diabetic mice?
Bianca Hemmeryckx, M. Hoylaerts, D. Gallacher, Hua-Rong Lu +4 more
2013European Journal of Pharmacology19 citations
Semantic Scholar
Murine models of obesity and hormonal therapy.
H. Lijnen
2011Thrombosis Research18 citations
Semantic Scholar

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D. Collen×13
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D. Collen — researcher profile on SciRah
E. Maquoi×6
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Ilse Scroyen×6
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B. van Hoef×5
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F. Lupu — researcher profile on SciRah

P. Carmeliet×4

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D. Demeulemeester×4

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D. Collen — researcher profile on SciRah