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Hwei-Ling Cheng · SciRah

Researcher profile · Semantic Scholar

Hwei-Ling Cheng

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Hwei-Ling Cheng — researcher profile on SciRah

h-index: 34
Works: 51
Citations: 14K

Most-cited papers

Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
A. Brunet, Lora B. Sweeney, J. Sturgill, Katrin F. Chua +13 more
2004Science3,376 citations
Semantic Scholar
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6.
R. Mostoslavsky, Katrin F. Chua, David B. Lombard, W. Pang +27 more
2006Cell1,539 citations Open access
Semantic Scholar
Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation
David B. Lombard, F. Alt, Hwei-Ling Cheng, J. Bunkenborg +16 more
2007Molecular and Cellular Biology1,223 citations Open access
Semantic Scholar
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
Hwei-Ling Cheng, R. Mostoslavsky, Shinichi Saito, J. Manis +6 more
2003Proceedings of the National Academy of Sciences of the United States of America1,132 citations Open access
Semantic Scholar
SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis.
A. Vaquero, Michael B Scher, Dong-Hoon Lee, A. Sutton +5 more
2006Genes & Development678 citations Open access
Semantic Scholar
Late embryonic lethality and impaired V (D)J recombination in mice lacking DNA ligase IV
K. Frank, J. Sekiguchi, K. Seidl, W. Swat +5 more
1998Nature605 citations
Semantic Scholar
Tissue-specific regulation of SIRT1 by calorie restriction.
Danica Chen, Joanne Bruno, Erin J. Easlon, Su-Ju Lin +3 more
2008Genes & Development576 citations Open access
Semantic Scholar
Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally
Yu Zhang, Sohee Kwon, Teppei Yamaguchi, F. Cubizolles +12 more
2008Molecular and Cellular Biology575 citations Open access
Semantic Scholar
Growth retardation and leaky SCID phenotype of Ku70-deficient mice.
Yan-Song Gu, K. Seidl, G. Rathbun, Cheng-Ming Zhu +10 more
1997Immunity483 citations Open access
Semantic Scholar
The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination.
Zhi-Ying Li, T. Otevrel, Yijie Gao, Hwei-Ling Cheng +4 more
1995Cell474 citations Open access
Semantic Scholar
CTCF Binding Elements Mediate Control of V(D)J Recombination
Chun-Guang Guo, Hyesuk Yoon, A. Franklin, Suvi Jain +16 more
2011Nature289 citations Open access
Semantic Scholar
Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice.
Sean Rooney, JoAnn Sekiguchi, Cheng-Ming Zhu, Hwei-Ling Cheng +7 more
2002Molecules and Cells289 citations Open access
Semantic Scholar
SIRT7 Represses Myc Activity to Suppress ER Stress and Prevent Fatty Liver Disease
Jiyung Shin, M. He, Yu-Fei Liu, Silvana Paredes +18 more
2013Cell Reports268 citations Open access
Semantic Scholar
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress.
Katrin F. Chua, R. Mostoslavsky, David B. Lombard, W. Pang +9 more
2005Cell Metabolism262 citations Open access
Semantic Scholar
RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein.
Ryushin Mizuta, Janine M. Lasalle, Hwei-Ling Cheng, Akira Shinohara +5 more
1997Proceedings of the National Academy of Sciences of the United States of America245 citations Open access
Semantic Scholar
ATM Damage Response and XLF Repair Factor are Functionally Redundant In Joining DNA Breaks
S. Zha, Chun-Guang Guo, C. Boboila, Valentyn Oksenych +8 more
2010Nature215 citations Open access
Semantic Scholar
Lymphocyte-Specific Compensation For XLF/Cernunnos End-Joining Functions In V(D)J Recombination
Gang Li, F. Alt, Hwei-Ling Cheng, James W. Brush +5 more
2008Molecules and Cells198 citations Open access
Semantic Scholar
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation
K. Saunders, K. Wiehe, Ming Tian, P. Acharya +31 more
2019Science159 citations Open access
Semantic Scholar
The NAD-dependent deacetylase SIRT2 is required for programmed necrosis
N. Narayan, I. H. Lee, Ronen Borenstein, Jun-Hui Sun +14 more
2012Nature147 citations
Semantic Scholar
Activated Ras signals differentiation and expansion of CD4+8+ thymocytes.
Wojciech Swat, Yoichi Shinkai, Hwei-Ling Cheng, L. Davidson +1 more
1996Proceedings of the National Academy of Sciences of the United States of America144 citations Open access
Semantic Scholar
Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells
S. Zha, F. Alt, Hwei-Ling Cheng, James W. Brush +1 more
2007Proceedings of the National Academy of Sciences of the United States of America122 citations Open access
Semantic Scholar
Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice
Hwei-Ling Cheng, B. Vuong, Uttiya Basu, A. Franklin +7 more
2009Proceedings of the National Academy of Sciences of the United States of America115 citations Open access
Semantic Scholar
A transforming growth factor beta 2 (TGF-beta 2)-like immunosuppressive factor in amniotic fluid and localization of TGF-beta 2 mRNA in the pregnant uterus
D. Altman, S. Schneider, D. Thompson, Hwei-Ling Cheng +1 more
1990Journal of Experimental Medicine114 citations Open access
Semantic Scholar
Structure of genes for membrane and secreted murine IgD heavy chains
Hwei-Ling Cheng, F. Blattner, L. Fitzmaurice, J. Frederic Mushinski +1 more
1982Nature112 citations
Semantic Scholar
A DNA repair defect in Chinese hamster ovary cells affects V(D)J recombination similarly to the murine scid mutation.
G. Taccioli, Hwei-Ling Cheng, A. J. Varghese, G. Whitmore +1 more
1994Journal of Biological Chemistry95 citations Open access
Semantic Scholar
The ARID Family Transcription Factor Bright Is Required for both Hematopoietic Stem Cell and B Lineage Development
C. Webb, J. Bryant, Melissa Popowski, Laura Allred +8 more
2011Molecular and Cellular Biology89 citations Open access
Semantic Scholar
Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells.
David H. Jung, C. Bassing, S. Fugmann, Hwei-Ling Cheng +2 more
2003Immunity78 citations Open access
Semantic Scholar
Tissue-specific regulation of SIRT 1 by calorie restriction
Danica Chen, Joanne Bruno, Erin Easlon, Su-Ju Lin +3 more
200857 citations
Semantic Scholar
Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndrome
F. Rucci, L. Notarangelo, A. Fazeli, L. Patrizi +18 more
2010Proceedings of the National Academy of Sciences of the United States of America52 citations Open access
Semantic Scholar
Leaky severe combined immunodeficiency and aberrant DNA rearrangements due to a hypomorphic RAG1 mutation.
William Giblin, M. Chatterji, Gerwin H. Westfield, T. Masud +7 more
2009Blood51 citations Open access
Semantic Scholar
Vaccination induces broadly neutralizing antibody precursors to HIV gp41
T. Schiffner, Ivy Phung, Rashmi Ray, A. Irimia +71 more
2024Nature Immunology49 citations Open access
Semantic Scholar
Molecular genetic characterization of XRCC4 function.
Ryushin Mizuta, Hwei-Ling Cheng, Yijie Gao, F. Alt
1997International Immunology46 citations
Semantic Scholar
Nonhomologous end-joining proteins are required for V(D)J recombination, normal growth, and neurogenesis.
J. Sekiguchi, Yi-Jie Gao, Yansong Gu, K. Frank +9 more
1999Cold Spring Harbor Symposia on Quantitative Biology43 citations
Semantic Scholar
Elements between the IgH variable (V) and diversity (D) clusters influence antisense transcription and lineage-specific V(D)J recombination
Cosmas C. Giallourakis, A. Franklin, Chun-Guang Guo, Hwei-Ling Cheng +8 more
2010Proceedings of the National Academy of Sciences of the United States of America39 citations Open access
Semantic Scholar
Activities involved in V(D)J recombination.
Guillermo E. Taccioli, G. Rathbun, Yoichi Shinkai, E. Oltz +5 more
1992Current Topics in Microbiology and Immunology28 citations
Semantic Scholar
Regulation of Activation-Induced Cytidine Deaminase DNA Deamination Activity in B Cells by Serine-38 Phosphorylation
Uttiya Basu, A. Franklin, B. Schwer, Hwei-Ling Cheng +2 more
2009Biochemical Society Transactions21 citations Open access
Semantic Scholar
RAB 22 and RAB 163 y mouse BRCA 2 : Proteins that specifically interact with the RAD 51 protein
Ryushin Mizuta, J. LaSalle, Hwei-Ling Cheng, A. Shinohara +5 more
199719 citations
Semantic Scholar
Mouse spleen and IgD-secreting plasmacytomas contain multiple IgD δ chain RNAs
L. Fitzmaurice, J. Owens, F. Blattner, Hwei-Ling Cheng +2 more
1982Nature16 citations
Semantic Scholar
GENETIC ASPECTS OF IgD EXPRESSION: I. ANALYSIS OF THE CµCδ COMPLEX IN COMMITTED AND UNCOMMITTED DNA
F. Blattner, J. Richards, A. Shen, M. Knapp +6 more
198213 citations
Semantic Scholar
GENETIC ASPECTS OF IgD EXPRESSION: III. FUNCTIONAL IMPLICATIONS OF THE SEQUENCE AND ORGANIZATION OF THE Cδ GENE
Philip W. Tucker, Hwei-Ling Cheng, J. Richards, L. Fitzmaurice +2 more
1982Annals of the New York Academy of Sciences10 citations
Semantic Scholar
Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models
Ming Tian, K. McGovern, Hwei-Ling Cheng, Peyton Waddicor +11 more
2020Proceedings of the National Academy of Sciences of the United States of America8 citations Open access
Semantic Scholar
Distinct IL-4 response mechanisms of the MHC gene Aα in different mouse B cell lines
M. Whitley, Hwei-Ling Cheng, T. Tomasi, M. Boothby
19937 citations
Semantic Scholar
An efficient and general method for sequencing immunoglobulin mRNAs.
A. Sood, Hwei-Ling Cheng, H. Kohler
1986JIM - Journal of Immunological Methods7 citations
Semantic Scholar
Retraction: The NAD-dependent deacetylase SIRT2 is required for programmed necrosis
N. Narayan, I. H. Lee, Ronen Borenstein, Jun-Hui Sun +14 more
2014Nature6 citations Open access
Semantic Scholar
An in vivo method for diversifying the functions of therapeutic antibodies
Ming Tian, Hwei-Ling Cheng, Michael T. Kimble, K. McGovern +7 more
2020Proceedings of the National Academy of Sciences of the United States of America5 citations Open access
Semantic Scholar
ON THE MECHANISM OF INTERNAL IMAGE VACCINES
H. Kohler, Hwei-Ling Cheng, A. Sood, M. Mcnamara-Ward +3 more
19862 citations
Semantic Scholar
Leaky SCID and aberrant DNA rearrangements due to a hypomorphic RAG1 mutation
William Giblin, M. Chatterji, Gerwin H. Westfield, T. Masud +8 more
20081 citations
Semantic Scholar
Author Correction: Vaccination induces broadly neutralizing antibody precursors to HIV gp41
T. Schiffner, Ivy Phung, Rashmi Ray, A. Irimia +71 more
2024Nature Immunology0 citations Open access
Semantic Scholar
OR.1. Hypomorphic Rag1 and Lig4 Mutants are a Model for Human Leaky SCID
F. Rucci, P. Poliani, Catherine T. Yan, JoAnn Sekiguchi +8 more
20080 citations
Semantic Scholar
murine ES cells Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient
S. Zha, Hwei-Ling Cheng, James W. Brush, Gang Li
20070 citations
Semantic Scholar

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F. Alt — researcher profile on SciRah
Katrin F. Chua×6
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