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Simon Steiger · SciRah

Researcher profile · Semantic Scholar

Simon Steiger

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Simon Steiger — researcher profile on SciRah

h-index: 10
Works: 35
Citations: 571

Most-cited papers

The pre-existing T cell landscape determines the response to bispecific T cell engagers in multiple myeloma patients.
M. Friedrich, P. Neri, N. Kehl, J. Michel +16 more
2023Cancer Cell229 citations Open access
Semantic Scholar
Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single‐cell transcriptomics
Stephan M. Tirier, Jan-Philipp Mallm, Simon Steiger, A. Poos +16 more
2021Nature Communications127 citations Open access
Semantic Scholar
Resolving therapy resistance mechanisms in multiple myeloma by multiomics subclone analysis
A. Poos, Nina Prokoph, M. Przybilla, Jan-Philipp Mallm +19 more
2023Blood54 citations Open access
Semantic Scholar
Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level
L. John, A. Poos, A. Brobeil, C. Schinke +34 more
2023Nature Communications41 citations Open access
Semantic Scholar
Bone marrow breakout lesions act as key sites for tumor-immune cell diversification in multiple myeloma
R. Lutz, A. Poos, L. Solé-Boldo, L. John +31 more
2025Science immunology22 citations Open access
Semantic Scholar
Local emergence and decline of a SARS-CoV-2 variant with mutations L452R and N501Y in the spike protein
Jan-Philipp Mallm, C. Bundschuh, Heeyoung Kim, N. Weidner +17 more
2021medRxiv18 citations Open access
Semantic Scholar
Pheno-seq – linking visual features and gene expression in 3D cell culture systems
Stephan M. Tirier, Jeongbin Park, Friedrich Preusser, Lisa Amrhein +16 more
2019Scientific Reports18 citations Open access
Semantic Scholar
Multiple myeloma long-term survivors exhibit sustained immune alterations decades after first-line therapy
R. Lutz, Florian Grünschläger, Malte Simon, Mohamed H. S. Awwad +27 more
2024Nature Communications17 citations Open access
Semantic Scholar
Dissection of gastric homeostasis in vivo facilitates permanent capture of isthmus stem cells in vitro
A. Huebner, Rebecca A. Gorelov, Ruslan M. Deviatiiarov, Samuel Demharter +7 more
2023Nature Cell Biology15 citations Open access
Semantic Scholar
IgE type multiple myeloma exhibits hypermutated phenotype and tumor reactive T cells
N. Kehl, M. Kilian, J. Michel, T. Wagner +16 more
2022Journal for ImmunoTherapy of Cancer10 citations Open access
Semantic Scholar
The Spatial Heterogeneity in Newly Diagnosed Multiple Myeloma Patients - from Sub-Clonal Architecture to the Immune Microenvironment
L. John, A. Poos, Stephan M. Tirier, Jan-Philipp Mallm +15 more
2021Blood6 citations Open access
Semantic Scholar
Bone Marrow Immune Signatures in Multiple Myeloma Are Linked to Tumor Heterogeneity and Treatment Outcome
Simon Steiger, R. Lutz, Nina Prokoph, S. Palit +31 more
2022Blood5 citations Open access
Semantic Scholar
OA-23 Resolving therapy resistance mechanisms in multiple myeloma by multi-omics subclone analysis
A. Poos, Nina Prokoph, M. Przybilla, Jan-Philipp Mallm +19 more
2023Clinical Lymphoma, Myeloma & Leukemia3 citations
Semantic Scholar
Latent effector T cells mediate immunotherapy responses in the bone marrow microenvironment.
N. Kehl, T. Wagner, Simon Steiger, T. Boschert +49 more
2026Cancer Cell2 citations Open access
Semantic Scholar
Conserved programs and specificities of T cells targeting hematological malignancies
T. Wagner, N. Kehl, Simon Steiger, T. Boschert +40 more
2025bioRxiv2 citations
Semantic Scholar
Evolution of SARS-CoV-2 in the RhineNeckar/Heidelberg Region 01/2021 07/2023
Christian Bundschuh, N. Weidner, Julian A. F. Klein, Tobias Rausch +18 more
2023medRxiv2 citations Open access
Semantic Scholar
T cell fitness and tumor specificity predict immunotherapy response in multiple myeloma
N. Kehl, Simon Steiger, T. Wagner, T. Boschert +9 more
2025Blood1 citations
Semantic Scholar
Tumor Reactive T Cells Drive Clinical Responses to Multiple Myeloma
T. Wagner, N. Kehl, Simon Steiger, T. Boschert +12 more
2024Blood1 citations
Semantic Scholar
OAB-007: Single-cell multiomic analysis identifies regulatory programs in relapsed/refractory multiple myeloma
A. Poos, M. Przybilla, Nina Prokoph, Jan-Philipp Malllm +15 more
2021Clinical Lymphoma, Myeloma & Leukemia1 citations
Semantic Scholar
PA-276 Latent Effector T Cells Mediate Immunotherapy Responses in the Bone Marrow Microenvironment
N. Kehl, T. Wagner, Simon Steiger, T. Boschert +20 more
2026Clinical Lymphoma, Myeloma & Leukemia0 citations
Semantic Scholar
Disagreement between demultiplexing methods reveals structured cell quality gradients in multiplexed single-cell data
Ezgi Sen, Simon Steiger, Mislav Basic, Nina Prokoph +14 more
2026bioRxiv0 citations
Semantic Scholar
Fiber intake associates with increased treatment response in patients with multiple myeloma along with changes in gut microbiome
L. Sester, I. Galeeva, J. de Castilhos, V. Borisov +23 more
2026Blood Advances0 citations Open access
Semantic Scholar
P-151 Dietary Oleic Acid Influences the Myeloma Immune Microenvironment and Improves Clinical Outcomes
L. Sester, J. de Castilhos, V. Borisov, A. Gambihler +18 more
2024Clinical Lymphoma, Myeloma & Leukemia0 citations
Semantic Scholar
Abstract 14: Identification of tumor-reactive T cell receptors through functional single cell interaction analyses for personalized T cell therapy
T. Wagner, N. Kehl, Simon Steiger, M. Kilian +10 more
2024Cancer Research0 citations
Semantic Scholar
Tumor Reactive T Cells Reside in the Bone Marrow and Are Associated with Clinical Response to Hematological Malignancies
T. Wagner, N. Kehl, Simon Steiger, M. Kilian +26 more
2023Blood0 citations Open access
Semantic Scholar
Progenitor-like cell type of an MLL-EDC4 fusion in acute myeloid leukemia
L. Schuster, Afzal P. Syed, Stephan M. Tirier, Simon Steiger +8 more
2023Blood Advances0 citations Open access
Semantic Scholar
P-220 Discovery of tumor-reactive T cell receptors by functional single cell interaction analyses in patients with newly diagnosed multiple myeloma
T. Wagner, N. Kehl, Simon Steiger, M. Kilian +10 more
2023Clinical Lymphoma, Myeloma & Leukemia0 citations
Semantic Scholar
Single-Cell Multi-Omics Reveal Longitudinal Dynamics of Clonal Architecture and Microenvironment Interactions in Relapsed-Refractory Myeloma
A. Poos, Nina Prokoph, M. Przybilla, Jan-Philipp Mallm +17 more
2022Blood0 citations Open access
Semantic Scholar
OAB-002: The preexisting T cell landscape determines response to T cell-engagers therapy in multiple myeloma
M. Friedrich, N. Kehl, P. Neri, J. Michel +16 more
2022Clinical Lymphoma, Myeloma & Leukemia0 citations
Semantic Scholar
OAB-027: Discovery of tumor-reactive T cell receptors in multiple myeloma
N. Kehl, Simon Steiger, Tim Wagner, Katharina Lindner +16 more
2022Clinical Lymphoma, Myeloma & Leukemia0 citations
Semantic Scholar
Discovery of Tumor Reactive T Cell Receptors in Newly Diagnosed Multiple Myeloma
M. Friedrich, N. Kehl, Simon Steiger, T. Wagner +21 more
2022Blood0 citations Open access
Semantic Scholar
P-060: Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single cell transcriptomics
K. Rippe, Stephan M. Tirier, Jan-Philipp Mallm, Simon Steiger +16 more
2021Clinical Lymphoma, Myeloma & Leukemia0 citations
Semantic Scholar
P-049: The spatial sub-clonal architecture in newly diagnosed myeloma patients revealed by whole genome and single-cell sequencing
L. John, A. Poos, Stephan M. Tirier, Jan-Philipp Mallm +14 more
2021Clinical Lymphoma, Myeloma & Leukemia0 citations
Semantic Scholar
pheno-seq – linking morphological features to gene expression in 3D cell culture systems
Stephan M. Tirier, Jeongbin Park, Friedrich Preusser, Lisa Amrhein +15 more
2018bioRxiv0 citations Open access
Semantic Scholar
Pheno-seq: linking visual features and gene expression in 3D cell culture systems
Stephan M. Tirier, Jeongbin Park, Friedrich Preusser, Lisa Amrhein +16 more
0 citations
Semantic Scholar

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