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C. Coutzac · SciRah

Researcher profile · Semantic Scholar

C. Coutzac

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C. Coutzac — researcher profile on SciRah

h-index: 19
Works: 68
Citations: 3,331

Most-cited papers

Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab
N. Chaput, P. Lepage, C. Coutzac, E. Soularue +14 more
2017Annals of Oncology1,159 citations Open access
Semantic Scholar
Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer
C. Coutzac, J. Jouniaux, A. Paci, J. Schmidt +21 more
2020Nature Communications463 citations Open access
Semantic Scholar
Cancer Immunotherapy with Anti-CTLA-4 Monoclonal Antibodies Induces an Inflammatory Bowel Disease.
L. Marthey, C. Mateus, C. Mussini, M. Nachury +15 more
2016Journal of Crohn's & Colitis311 citations Open access
Semantic Scholar
Enterocolitis due to immune checkpoint inhibitors: a systematic review
E. Soularue, P. Lepage, J. Colombel, C. Coutzac +6 more
2018Gut238 citations
Semantic Scholar
Inflammatory gastrointestinal diseases associated with PD-1 blockade antibodies
M. Collins, J. Michot, F. Danlos, C. Mussini +15 more
2017Annals of Oncology149 citations Open access
Semantic Scholar
Colon Immune-Related Adverse Events: Anti-CTLA-4 and Anti-PD-1 Blockade Induce Distinct Immunopathological Entities
C. Coutzac, J. Adam, E. Soularue, M. Collins +16 more
2017Journal of Crohn's & Colitis147 citations Open access
Semantic Scholar
Immunotherapy in advanced gastric cancer, is it the future?
C. Coutzac, S. Pernot, N. Chaput, A. Zaanan
2019Critical reviews in oncology/hematology125 citations
Semantic Scholar
Trastuzumab Deruxtecan or Ramucirumab plus Paclitaxel in Gastric Cancer.
K. Shitara, E. Van Cutsem, M. Gümüş, S. Lonardi +21 more
2025New England Journal of Medicine104 citations
Semantic Scholar
Efficacy of immune checkpoint inhibitors in microsatellite unstable/mismatch repair-deficient advanced pancreatic adenocarcinoma: an AGEO European Cohort.
Julien Taïeb, L. Sayah, K. Heinrich, V. Kunzmann +16 more
2023European Journal of Cancer94 citations Open access
Semantic Scholar
Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab.
N. Chaput, P. Lepage, C. Coutzac, E. Soularue +14 more
2019Annals of Oncology62 citations Open access
Semantic Scholar
IL-15 Trans-Signaling with the Superagonist RLI Promotes Effector/Memory CD8+ T Cell Responses and Enhances Antitumor Activity of PD-1 Antagonists
M. Desbois, P. LeVu, C. Coutzac, E. Marcheteau +11 more
2016Journal of Immunology61 citations
Semantic Scholar
Evolution and recurrence of gastrointestinal immune-related adverse events induced by immune checkpoint inhibitors.
A. de Malet, Guillemette Antoni, M. Collins, E. Soularue +7 more
2019European Journal of Cancer58 citations
Semantic Scholar
Why is immunotherapy effective (or not) in patients with MSI/MMRD tumors?
L. Nebot-Bral, C. Coutzac, P. Kannouche, N. Chaput
2019Bulletin du Cancer41 citations
Semantic Scholar
Immunotherapy in MSI/dMMR tumors in the perioperative setting: The IMHOTEP trial.
C. Coutzac, F. Bibeau, M. Ben Abdelghani, T. Aparicio +17 more
2022Digestive and Liver Disease31 citations Open access
Semantic Scholar
Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab.
N. Chaput, P. Lepage, C. Coutzac, E. Soularue +14 more
201927 citations Open access
Semantic Scholar
Gemcitabine and Paclitaxel Versus Gemcitabine Alone After 5-Fluorouracil, Oxaliplatin, and Irinotecan in Metastatic Pancreatic Adenocarcinoma: A Randomized Phase III PRODIGE 65-UCGI 36-GEMPAX UNICANCER Study
C. de la Fouchardiére, D. Malka, C. Cropet, S. Chabaud +22 more
2024Journal of Clinical Oncology25 citations
Semantic Scholar
Cancer and immunotherapy: a role for microbiota composition.
F. Pham, F. Moinard-Butot, C. Coutzac, N. Chaput
2021European Journal of Cancer25 citations Open access
Semantic Scholar
Inflammatory bowel disease and cancer response due to anti-CTLA-4: is it in the flora?
F. Carbonnel, E. Soularue, C. Coutzac, N. Chaput +3 more
2017Seminars in Immunopathology23 citations
Semantic Scholar
BRAF + EGFR +/- MEK inhibitors after immune checkpoint inhibitors in BRAF V600E mutated and deficient mismatch repair or microsatellite instability high metastatic colorectal cancer.
M. Ambrosini, D. Tougeron, D. Modest, R. Guimbaud +16 more
2024European Journal of Cancer20 citations Open access
Semantic Scholar
Efficacy of pembrolizumab and vorinostat combination in patients with recurrent and/or metastatic squamous cell carcinomas: a phase 2 basket trial
E. Borcoman, B. Cabarrou, M. Francisco, Frédéric Bigot +32 more
2025Nature Cancer18 citations Open access
Semantic Scholar
Final analysis of the randomized phase 2 part of the ASPEN-06 study: A phase 2/3 study of evorpacept (ALX148), a CD47 myeloid checkpoint inhibitor, in patients with HER2-overexpressing gastric/gastroesophageal cancer (GC).
K. Shitara, Z. Wainberg, J. Tabernero, E. Van Cutsem +13 more
2025Journal of Clinical Oncology17 citations
Semantic Scholar
SARS-CoV-2 vaccines for cancer patients treated with immunotherapies: Recommendations from the French society for ImmunoTherapy of Cancer (FITC)
Marie-Léa Gauci, C. Coutzac, R. Houot, A. Marabelle +1 more
2021European Journal of Cancer15 citations Open access
Semantic Scholar
Prognostic Models From Transcriptomic Signatures of the Tumor Microenvironment and Cell Cycle in Stage III Colon Cancer From PETACC-8 and IDEA-France Trials
C. Gallois, M. Sroussi, T. André, S. Mouillet-Richard +17 more
2025Journal of Clinical Oncology11 citations Open access
Semantic Scholar
Neoadjuvant immunotherapy for nonmetastatic dMMR/MSI colon cancer: a real-world retrospective AGEO study
C. Lemaire, A. Boilève, G. Manceau, C. Coutzac +10 more
2025ESMO Open10 citations Open access
Semantic Scholar
Advanced oesophago-gastric adenocarcinoma in older patients in the era of immunotherapy. A review of the literature.
C. de la Fouchardiére, L. Decoster, E. Samalin, C. Terret +4 more
2021Cancer Treatment Reviews9 citations Open access
Semantic Scholar
Ezabenlimab and induction chemotherapy followed by adaptive chemoradiotherapy in patients with stage 3 squamous cell anal carcinoma (INTERACT-ION): an open-label, single-arm, phase 2 trial.
Stefano Kim, J. Boustani, S. Iseas, D. Vernerey +15 more
2025The Lancet Oncology8 citations Open access
Semantic Scholar
First-line chemotherapy with raltitrexed in metastatic colorectal cancer: an Association des Gastro-entérologues Oncologues (AGEO) multicentre study.
C. Gallois, E. Hafliger, É. Auclin, A. Perret +14 more
2021Digestive and Liver Disease8 citations Open access
Semantic Scholar
Immunotherapy for localized dMMR/MSI tumors: First interim analysis of the IMHOTEP trial.
C. de la Fouchardiére, A. Zaanan, R. Cohen, S. Le Sourd +15 more
2023Journal of Clinical Oncology7 citations
Semantic Scholar
Chemotherapy in advanced pancreatic adenosquamous carcinoma: A retrospective multicenter AGEO study
M. Auvray-Kuentz, V. Hautefeuille, L. de Mestier, C. Coutzac +15 more
2022International Journal of Cancer7 citations Open access
Semantic Scholar
Sequential Treatment With Trifluridine/Tipiracil and Regorafenib in Refractory Metastatic Colorectal Cancer Patients: An AGEO Prospective "Real-World Study".
C. Coutzac, I. Trouilloud, P. Artru, J. Henriques +11 more
2022Clinical colorectal cancer7 citations Open access
Semantic Scholar
Precision medicine for patients with gastro-oesophageal cancer: A subset analysis of the ProfiLER program
P. Cassier, C. Peyramaure, V. Attignon, L. Eberst +17 more
2021Translational Oncology7 citations Open access
Semantic Scholar
Targeting HER2 in metastatic gastroesophageal adenocarcinomas: What is new?
C. Coutzac, Paméla Funk-Debleds, A. Cattey-Javouhey, F. Desseigne +4 more
2022Bulletin du Cancer6 citations Open access
Semantic Scholar
A Promising Biomarker and Therapeutic Target in Patients with Advanced PDAC: The Stromal Protein βig-h3
C. de la Fouchardiére, Pia Gamradt, S. Chabaud, Maxime Raddaz +16 more
2022Journal of Personalized Medicine6 citations Open access
Semantic Scholar
Laparoscopic Extended Segmentectomy VIII Guided by Three-Dimensional Reconstruction and Hepatic Veins with a Cranio-Caudal Approach
A. Dupré, Charles Buiron, L. De Crignis, G. Bouroche +2 more
2024Annals of Surgical Oncology5 citations Open access
Semantic Scholar
Hyperprogressive Disease After Combined Anti-PD-L1 and Anti-CTLA-4 Immunotherapy for MSI-H/dMMR Gastric Cancer: A Case Report
R. Varnier, Thibaut Garrivier, E. Hafliger, Aymeric Favre +15 more
2021Frontiers in Oncology5 citations Open access
Semantic Scholar
Estimating causal effects of time-dependent exposures on a binary endpoint in a high-dimensional setting
V. Asvatourian, C. Coutzac, N. Chaput, C. Robert +2 more
2018BMC Medical Research Methodology5 citations Open access
Semantic Scholar
Efficacy of immunotherapy in gastrointestinal (GI) tumors with mismatch repair deficient (MMRd) unusual phenotype: an AGEO real-world study
E. Alouani, J. Taieb, D. Tougeron, G. Roces +20 more
2025Journal for ImmunoTherapy of Cancer4 citations Open access
Semantic Scholar
Triplet chemotherapy with or without bevacizumab as first line treatment for metastatic colorectal cancer: An AGEO multicenter real-world study.
R. Varnier, C. Toullec, S. Philonenko, A. Dupré +13 more
2024Digestive and Liver Disease3 citations Open access
Semantic Scholar
Trifluridine/tipiracil or regorafenib in refractory metastatic colorectal cancer patients: An AGEO prospective “real life” study.
C. Coutzac, I. Trouilloud, P. Artru, J. Henriques +10 more
2020Journal of Clinical Oncology3 citations
Semantic Scholar
105PBaseline gut microbiota in metastatic melanoma patients treated with ipilimumab: Relation with clinical response and colitis
N. Chaput, P. Lepage, C. Coutzac, E. Soularue +5 more
20173 citations Open access
Semantic Scholar
Predictive and prognostic factors of efficacy of third-line chemotherapy in patients with unresectable pancreatic cancer: a cohort-based study
C. Evrard, Antoine Pelras, Simon Rivet, J. Bachet +34 more
2025The Oncologist2 citations Open access
Semantic Scholar
Trifluridine/tipiracil + oxaliplatin ± nivolumab vs FOLFOX ± nivolumab in HER2 negative advanced oesogastric adenocarcinoma: The PRODIGE73-UCGI40-LOGICAN trial.
D. Botsen, S. Chabaud, Hervé Perrier, H. Ammarguellat +22 more
2024Digestive and Liver Disease2 citations Open access
Semantic Scholar
Ezabenlimab (BI 754091) plus modified docetaxel, cisplatin, and 5-fluorouracil (mDCF) followed by chemoradiotherapy (CRT) in patients (pts) with stage III squamous cell anal carcinoma (SCCA): Early efficacy endpoint results from the phase II INTERACT-ION study.
Stefano Kim, J. Boustani, D. Vernerey, L. Evesque +15 more
2024Journal of Clinical Oncology2 citations
Semantic Scholar
[New AMM: Nivolumab as an adjuvant for oesophageal and gastroesophageal junction cancer].
J. Chartier, C. Coutzac
2022Bulletin du Cancer2 citations
Semantic Scholar
493O STAR-221: A phase III study of first-line (1L) domvanalimab (D), zimberelimab (Z), and chemotherapy (chemo) vs nivolumab (N) + chemo in advanced HER2-negative gastric, gastroesophageal junction, or esophageal adenocarcinoma (GC/GEJC/EAC)
Y. Janjigian, S. Rha, Z. Wainberg, S. Klempner +16 more
2026Annals of Oncology1 citations Open access
Semantic Scholar
Assessment of pathologic response in the colorectal cancer cohort of the IMHOTEP phase II trial of neoadjuvant pembrolizumab in dMMR/MSI tumors.
F. Bibeau, Racha Mansar, Franck Monnien, A. de Montfort +3 more
2025Journal of Clinical Oncology1 citations Open access
Semantic Scholar
Maintenance with OSE2101 plus FOLFIRI vs FOLFIRI alone after FOLFIRINOX (FFX) induction in patients (Pts) with advanced pancreatic ductal adenocarcinoma (aPDAC): Primary endpoint results of a randomized TEDOPAM GERCOR D17-01 PRODIGE 63 trial.
A. Turpin, E. Mitry, O. Bouché, Yves Rinaldi +16 more
2025Journal of Clinical Oncology1 citations Open access
Semantic Scholar
496 CD47 expression as a predictive biomarker for evorpacept in HER2-positive gastric/gastroesophageal cancer from the Phase 2 randomized ASPEN-06 trial
Z. Wainberg, Keun-Wook Lee, J. Tabernero, E. Van Cutsem +12 more
2025Regular and Young Investigator Award Abstracts1 citations Open access
Semantic Scholar
[New AMM: Nivolumab for advanced oesophageal squamous cell carcinomia after first line of chemotherapy].
Mathilde Reich, C. Coutzac
2021Bulletin du Cancer1 citations
Semantic Scholar
Immune checkpoint inhibitor sensitivity of DNA repair deficient tumors.
P. Rochefort, F. Desseigne, V. Bonadona, S. Dussart +3 more
2021Immunotherapy1 citations
Semantic Scholar

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C. de la Fouchardiére×16
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C. de la Fouchardiére — researcher profile on SciRah
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C. Mateus — researcher profile on SciRah

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M. Collins — researcher profile on SciRah

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