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Alena Heimsoeth · SciRah

Researcher profile · Semantic Scholar

Alena Heimsoeth

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Alena Heimsoeth — researcher profile on SciRah

h-index: 10
Works: 16
Citations: 533

Most-cited papers

Overcoming EGFRG724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors
J. Fassunke, Fabienne Müller, M. Keul, S. Michels +35 more
2018Nature Communications133 citations Open access
Semantic Scholar
The next tier of EGFR resistance mutations in lung cancer
H. Tumbrink, Alena Heimsoeth, M. Sos
2020Oncogene91 citations
Semantic Scholar
Functional synapses between neurons and small cell lung cancer
V. Sakthivelu, A. Schmitt, Franka Odenthal, Kristiano Ndoci +71 more
2025Nature70 citations Open access
Semantic Scholar
MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I
J. Brägelmann, C. Lorenz, S. Borchmann, K. Nishii +35 more
2021Nature Communications68 citations Open access
Semantic Scholar
SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate
D. Nettersheim, Alena Heimsoeth, S. Jostes, S. Schneider +3 more
2016OncoTarget56 citations Open access
Semantic Scholar
Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S
J. Lategahn, M. Keul, Philip Klövekorn, H. Tumbrink +25 more
2019Chemical Science30 citations Open access
Semantic Scholar
Resistance to MET inhibition in MET-dependent NSCLC and therapeutic activity after switching from type I to type II MET inhibitors.
R. Riedel, J. Fassunke, H. Tumbrink, A. Scheel +25 more
2022European Journal of Cancer29 citations
Semantic Scholar
TCam-2 Cells Deficient for SOX2 and FOXA2 Are Blocked in Differentiation and Maintain a Seminoma-Like Cell Fate In Vivo
D. Nettersheim, S. Vadder, S. Jostes, Alena Heimsoeth +1 more
2019Cancers23 citations Open access
Semantic Scholar
Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors.
J. Lategahn, H. Tumbrink, Carsten Schultz-Fademrecht, Alena Heimsoeth +23 more
2022Journal of Medicinal Chemistry17 citations
Semantic Scholar
Characterizing evolutionary dynamics reveals strategies to exhaust the spectrum of subclonal resistance in EGFR-mutant lung cancer.
Nina Müller, C. Lorenz, Jenny Ostendorp, Felix S Heisel +14 more
2023Cancer Research11 citations Open access
Semantic Scholar
Functional synapses between small cell lung cancer and glutamatergic neurons
A. Schmitt, V. Sakthivelu, Kristiano Ndoci, G. Wani +36 more
2023bioRxiv10 citations Open access
Semantic Scholar
Overcoming EGFRG724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors
J. Fassunke, Fabienne Müller, M. Keul, S. Michels +35 more
2018Nature Communications2 citations Open access
Semantic Scholar
MYC-MIZ1 Complexes at Enhancers Tune Neuroendocrine Identity of Small Cell Lung Cancer
L. Fröhlich, H. Tumbrink, Bikash Adhikari, Margarita Rempe +24 more
2026bioRxiv0 citations
Semantic Scholar
Publisher Correction: Functional synapses between neurons and small cell lung cancer
V. Sakthivelu, A. Schmitt, Franka Odenthal, Kristiano Ndoci +71 more
2025Nature0 citations Open access
Semantic Scholar
Abstract LBA010: Therapeutic stimulation of nucleic acid receptor RIG-I enhances efficacy of kinase inhibitor treatment in oncogene-driven tumors
J. Brägelmann, C. Lorenz, S. Borchmann, K. Nishii +10 more
2021Poster Presentations - Late-Breaking Proffered Abstracts0 citations
Semantic Scholar
Targeting EGFR Ex20 mutant lung cancer with the wild type sparing kinase inhibitor PRB001.
M. Sos, H. Tumbrink, Carsten Schultz-Fademrecht, J. Lategahn +11 more
2019Journal of Clinical Oncology0 citations
Semantic Scholar

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