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P. D. Sbarba · SciRah

Researcher profile · Semantic Scholar

P. D. Sbarba

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P. D. Sbarba — researcher profile on SciRah

h-index: 22
Works: 86
Citations: 1,947

Most-cited papers

The role of hypoxia in the maintenance of hematopoietic stem cells.
M. G. Cipolleschi, P. D. Sbarba, M. Olivotto
1993Blood413 citations
Semantic Scholar
Primitive human HPCs are better maintained and expanded in vitro at 1 percent oxygen than at 20 percent
Z. Ivanovic, P. D. Sbarba, F. Trimoreau, J. Faucher +1 more
2000Transfusion145 citations
Semantic Scholar
Nerve Growth Factor Inhibits Apoptosis in Memory B Lymphocytes via Inactivation of p38 MAPK, Prevention of Bcl-2 Phosphorylation, and Cytochrome c Release*
M. Torcia, G. De Chiara, L. Nencioni, S. Ammendola +11 more
2001Journal of Biological Chemistry133 citations Open access
Semantic Scholar
Transmodulation of Cell Surface Regulatory Molecules via Ectodomain Shedding
P. D. Sbarba, E. Rovida
2002Biological chemistry98 citations
Semantic Scholar
Hypoxia maintains and interleukin-3 reduces the pre-colony-forming cell potential of dividing CD34(+) murine bone marrow cells.
Z. Ivanovic, F. Belloc, J. Faucher, M. Cipolleschi +2 more
2002Experimental Hematology90 citations Open access
Semantic Scholar
Severe hypoxia enhances the formation of erythroid bursts from human cord blood cells and the maintenance of BFU-E in vitro.
M. G. Cipolleschi, G. D'Ippolito, P. Bernabei, R. Caporale +6 more
1997Experimental Hematology84 citations
Semantic Scholar
The expansion of murine bone marrow cells preincubated in hypoxia as an in vitro indicator of their marrow-repopulating ability
M. Cipolleschi, E. Rovida, Z. Ivanovic, V. Praloran +2 more
2000Leukemia73 citations Open access
Semantic Scholar
Hypoxia suppresses BCR/Abl and selects imatinib-insensitive progenitors within clonal CML populations
Serena Giuntoli, E. Rovida, V. Barbetti, M. Cipolleschi +2 more
2006Leukemia70 citations Open access
Semantic Scholar
Hypoxia Modifies Proliferation and Differentiation of CD34+ CML Cells
V. Desplat, J. Faucher, F. Mahon, P. D. Sbarba +2 more
2002Stem Cells62 citations
Semantic Scholar
The metabolically-modulated stem cell niche: a dynamic scenario regulating cancer cell phenotype and resistance to therapy
E. Rovida, S. Peppicelli, Silvia Bono, F. Bianchini +6 more
2014Cell Cycle49 citations Open access
Semantic Scholar
v-raf confers CSF-1 independent growth to a macrophage cell line and leads to immediate early gene expression without MAP-kinase activation.
D. Büscher, P. D. Sbarba, R. Hipskind, U. Rapp +2 more
1993Oncogene49 citations
Semantic Scholar
IFN-gamma/lipopolysaccharide activation of macrophages is associated with protein kinase C-dependent down-modulation of the colony-stimulating factor-1 receptor.
M. Baccarini, P. D. Sbarba, D. Buscher, A. Bartocci +1 more
1992Journal of Immunology49 citations Open access
Semantic Scholar
Low M r Phosphotyrosine Protein Phosphatase Associates and Dephosphorylates p125 Focal Adhesion Kinase, Interfering with Cell Motility and Spreading*
S. Rigacci, E. Rovida, P. D. Sbarba, A. Berti
2002Journal of Biological Chemistry48 citations Open access
Semantic Scholar
Selective anti-leukaemic activity of low-dose histone deacetylase inhibitor ITF2357 on AML1/ETO-positive cells
V. Barbetti, A. Gozzini, E. Rovida, Andrea Morandi +6 more
2008Oncogene47 citations
Semantic Scholar
Combined inhibition of indoleamine 2,3‐dioxygenase and nitric oxide synthase modulates neurotoxin release by interferon‐γ‐activated macrophages
A. Chiarugi, P. D. Sbarba, Alessandro Paccagnini, S. Donnini +2 more
2000Journal of Leukocyte Biology44 citations
Semantic Scholar
Environmental restrictions within tumor ecosystems select for a convergent, hypoxia-resistant phenotype of cancer stem cells
M. Olivotto, P. D. Sbarba
2008Cell Cycle40 citations Open access
Semantic Scholar
Hemopoietic progenitor cells are sensitive to the cytostatic effect of pyruvate.
P. D. Sbarba, M. G. Cipolleschi, M. Olivotto
1987Experimental Hematology38 citations
Semantic Scholar
Chromatin-associated CSF-1R binds to the promoter of proliferation-related genes in breast cancer cells
V. Barbetti, A. Morandi, I. Tusa, G. Digiacomo +8 more
2013Oncogene34 citations Open access
Semantic Scholar
CXCR3 and αEβ7 integrin identify a subset of CD8+ mature thymocytes that share phenotypic and functional properties with CD8+ gut intraepithelial lymphocytes
F. Annunziato, L. Cosmi, F. Liotta, E. Lazzeri +11 more
2005Gut30 citations Open access
Semantic Scholar
AML1/ETO sensitizes via TRAIL acute myeloid leukemia cells to the pro-apoptotic effects of hypoxia
V. Barbetti, I. Tusa, Mg Cipolleschi, E. Rovida +1 more
2013Cell Death and Disease27 citations Open access
Semantic Scholar
Interleukin‐4 rapidly down‐modulates the macrophage colony‐stimulating factor receptor in murine macrophages
P. D. Sbarba, E. Rovida, B. Caciagli, L. Nencioni +4 more
1996Journal of Leukocyte Biology24 citations
Semantic Scholar
Functional specificity of cytoplasmic and transmembrane tyrosine kinases: identification of 130- and 75-kilodalton substrates of c-fps/fes tyrosine kinase in macrophages
L. Areces, P. D. Sbarba, M. Jücker, E. Stanley +1 more
1994Molecular and Cellular Biology24 citations Open access
Semantic Scholar
Interleukin 2 down-modulates the macrophage colony-stimulating factor receptor in murine macrophages.
P. D. Sbarba, L. Nencioni, D. Labardi, E. Rovida +2 more
1996Cytokine22 citations
Semantic Scholar
Increased phosphorylation of the colony stimulating factor-1 receptor following transmembrane signaling.
M. Baccarini, W. Li, P. D. Sbarba, E. Stanley
1991Receptor22 citations
Semantic Scholar
Chronic myeloid leukemia progenitor cells require autophagy when leaving hypoxia-induced quiescence
A. Ianniciello, P. Dumas, C. Drullion, Amélie V. Guitart +11 more
2017OncoTarget21 citations Open access
Semantic Scholar
Methylation pattern analysis in prostate cancer tissue: identification of biomarkers using an MS-MLPA approach
G. Gurioli, S. Salvi, Filippo Martignano, F. Foca +7 more
2016Journal of Translational Medicine20 citations Open access
Semantic Scholar
The low-molecular-weight phosphotyrosine protein phosphatase, when overexpressed, reduces the mitogenic response to macrophage colony-stimulating factor and tyrosine phosphorylation of its receptor.
E. Rovida, S. Rigacci, Alessandro Paccagnini, P. D. Sbarba +1 more
1998Biochemical and Biophysical Research Communications - BBRC20 citations
Semantic Scholar
The Culture-Repopulating Ability Assays and Incubation in Low Oxygen: A Simple Way to Test Drugs on Leukaemia Stem or Progenitor Cells
M. Cipolleschi, E. Rovida, P. D. Sbarba
2013Current pharmaceutical design18 citations Open access
Semantic Scholar
Putative liver progenitor cells: conditions for long-term survival in culture
M. Agelli, E. Halay, L. Reid, P. D. Sbarba +2 more
1997The Histochemical Journal17 citations
Semantic Scholar
Opposite effects of different doses of MCSF on ERK phosphorylation and cell proliferation in macrophages
E. Rovida, M. Baccarini, M. Olivotto, P. D. Sbarba
2002Oncogene16 citations
Semantic Scholar
Colony-Stimulating Factor-1 Receptor in the Polarization of Macrophages:A Target for Turning Bad to Good Ones?
E. Rovida, P. D. Sbarba
201515 citations Open access
Semantic Scholar
A Simple, One‐Step Clonal Assay Allows the Sequential Detection of Committed (CFU‐GM‐like) Progenitors and Several Subsets of Primitive (HPP‐CFC) Murine Progenitors
Z. Ivanovic, B. Bartolozzi, P. Bernabei, M. Cipolleschi +3 more
1999Stem Cells15 citations
Semantic Scholar
Salarin C inhibits the maintenance of chronic myeloid leukemia progenitor cells
E. Del Poggetto, M. Tanturli, N. Ben-Califa, A. Gozzini +8 more
2015Cell Cycle11 citations Open access
Semantic Scholar
Independently arising macrophage mutants dissociate growth factor-regulated survival and proliferation.
J. Pollard, C. J. Morgan, P. D. Sbarba, C. Cheers +1 more
1991Proceedings of the National Academy of Sciences of the United States of America11 citations Open access
Semantic Scholar
Metabolic Aspects of Cell Cycle Regulation in Normal and Cancer Cells
M. Olivotto, A. Arcangeli, R. Caldini, M. Chevanne +2 more
1984Toxicologic pathology (Print)11 citations Open access
Semantic Scholar
Constitutive activation of the MAPK pathway mediates v-fes-induced mitogenesis in murine macrophages.
E. Rovida, F. Marra, M. Baccarini, P. D. Sbarba
2000Blood9 citations
Semantic Scholar
Severe hypoxia selects hematopoietic progenitors with stem cell potential from primary Myelodysplastic syndrome bone marrow cell cultures
E. Masala, Ana Valencia-Martinez, S. Pillozzi, Tommaso Rondelli +6 more
2018OncoTarget8 citations Open access
Semantic Scholar
Alterations in CSF-1 receptor expression and protein tyrosine phosphorylation in autonomous mutants of a CSF-1 dependent macrophage cell line.
P. D. Sbarba, J. W. Pollard, E. Stanley
1991Growth Factors7 citations
Semantic Scholar
Apoptosis : molecular regulation of cell death and hematologic malignancies.
V. Chiarugi, M. Cinelli, L. Magnelli, P. D. Sbarba
2001Methods in Molecular Medicine5 citations
Semantic Scholar
Cancer stemness and progression: mitochondria on the stage
P. Chiarugi, P. D. Sbarba
2015OncoTarget4 citations Open access
Semantic Scholar
p38 and cancer: Yang gets yin
E. Rovida, P. D. Sbarba
2008Cancer Biology & Therapy4 citations Open access
Semantic Scholar
Molecular biology (pre-clinical)
L. Malorni, M. Giuliano, I. Migliaccio, C. Creighton +115 more
20123 citations Open access
Semantic Scholar
Apoptosis: Molecular regulation of cell death and hematologic malignancies
V. Chiarugi, M. Cinelli, L. Magnelli, P. D. Sbarba
2002Molecular Biotechnology3 citations
Semantic Scholar
A comparative kinetic analysis of proliferation in vitro of Con‐A‐treated splenocytes and syngeneic leukaemia cells
M. Olivotto, Vieri Boddi, P. D. Sbarba, A. Arcangeli
1982Cell and tissue kinetics3 citations Open access
Semantic Scholar
Methylation pattern analysis in prostate cancer tissue: identification of biomarkers using an MS-MLPA approach
G. Gurioli, S. Salvi, Filippo Martignano, F. Foca +7 more
2016Journal of Translational Medicine2 citations Open access
Semantic Scholar
Cytokine Receptor Signal Transduction Mechanisms in Immuno-Hematopoietic Cells
V. Chiarugi, P. D. Sbarba, L. Magnelli, P. Chiarugi +2 more
1993Tumori2 citations
Semantic Scholar
Abstract 3904: Inhibition of the ERK5 pathway as a novel approach to target human chronic myeloid leukemia stem cells
I. Tusa, G. Cheloni, N. Gray, A. Gozzini +2 more
20171 citations
Semantic Scholar
An innovative epigenetic strategy for retinoblastoma treatment
N. Ilaria, Cinti Caterina, P. D. Sbarba
20171 citations
Semantic Scholar
Different BCR/Abl protein suppression patterns as a converging trait of chronic myeloid leukemia cell adaptation to energy restriction
Silvia Bono, Matteo Lulli, V. D'Agostino, F. Di Gesualdo +5 more
2016OncoTarget1 citations Open access
Semantic Scholar
Targeting Chronic Myeloid Leukemia Stem Cells through Pharmacological Inhibition of HIF-1α
G. Cheloni, Michele Tanturli, DeSouza Ho Ngoc, Shan Yi +4 more
20161 citations
Semantic Scholar

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E. Rovida×21
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E. Rovida — researcher profile on SciRah
M. Olivotto×9
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M. Olivotto — researcher profile on SciRah
M. Cipolleschi×9
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M. Cipolleschi — researcher profile on SciRah
Z. Ivanovic×6
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I. Tusa — researcher profile on SciRah

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M. G. Cipolleschi×5

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V. Praloran — researcher profile on SciRah

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V. Barbetti — researcher profile on SciRah

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G. Cheloni — researcher profile on SciRah

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J. Faucher — researcher profile on SciRah

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L. Nencioni — researcher profile on SciRah