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F. Kottakis · SciRah

Researcher profile · Semantic Scholar

F. Kottakis

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F. Kottakis — researcher profile on SciRah

h-index: 17
Works: 36
Citations: 1,910

Most-cited papers

LKB1 loss links serine metabolism to DNA methylation and tumourigenesis
F. Kottakis, Brandon Nicolay, Ahlima Roumane, R. Karnik +15 more
2016Nature314 citations Open access
Semantic Scholar
YAP inhibition restores hepatocyte differentiation in advanced HCC leading to tumor regression
Julien Fitamant, F. Kottakis, S. Benhamouche, Helen S Tian +18 more
2015Cell Reports238 citations Open access
Semantic Scholar
FGF-2 regulates cell proliferation, migration and angiogenesis through an NDY1/KDM2B-miR-101-EZH2 pathway
F. Kottakis, C. Polytarchou, Parthena F Foltopoulou, Ioannis Sanidas +2 more
2011Molecules and Cells226 citations Open access
Semantic Scholar
MicroRNAs differentially regulated by Akt isoforms, control EMT and stem cell renewal in cancer cells
D. Iliopoulos, C. Polytarchou, Maria Hatziapostolou, F. Kottakis +3 more
2009Science Signaling213 citations Open access
Semantic Scholar
ERKs in cancer: friends or foes?
X. Deschênes-Simard, F. Kottakis, Sylvain Meloche, G. Ferbeyre
2014Cancer Research202 citations
Semantic Scholar
Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation
C. Polytarchou, D. Iliopoulos, Maria Hatziapostolou, F. Kottakis +3 more
2011Cancer Research137 citations Open access
Semantic Scholar
Phosphoproteomics screen reveals Akt isoform-specific signals linking RNA processing to lung cancer
Ioannis Sanidas, C. Polytarchou, Maria Hatziapostolou, Scott A. Ezell +7 more
2014Molecules and Cells118 citations Open access
Semantic Scholar
Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation
Brandon Nicolay, P. Danielian, F. Kottakis, John D. Lapek +12 more
2015Genes & Development87 citations Open access
Semantic Scholar
NDY1/KDM2B functions as a master regulator of Polycomb complexes and controls self-renewal of breast cancer stem cells
F. Kottakis, Parthena F Foltopoulou, Ioannis Sanidas, Patricia J. Keller +9 more
2014Cancer Research81 citations Open access
Semantic Scholar
LKB1-AMPK axis revisited
F. Kottakis, N. Bardeesy
2012Cell Research41 citations Open access
Semantic Scholar
Effects of mastic gum Pistacia lentiscus var. Chia on innate cellular immune effectors
F. Kottakis, K. Kouzi-Koliakou, S. Pendás, J. Kountouras +1 more
2009European Journal of Gastroenterology and Hepathology35 citations
Semantic Scholar
Helicobacter pylori neutrophil‐activating protein activates neutrophils by its C‐terminal region even without dodecamer formation, which is a prerequisite for DNA protection – novel approaches against Helicobacter pylori inflammation
F. Kottakis, G. Papadopoulos, E. Pappa, P. Cordopatis +2 more
2008The FEBS Journal34 citations Open access
Semantic Scholar
Circumventing senescence is associated with stem cell properties and metformin sensitivity
X. Deschênes-Simard, Maxime Parisotto, Marie-Camille Rowell, B. Le Calvé +8 more
2019Aging Cell33 citations Open access
Semantic Scholar
Tumor progression locus 2 regulates signal-induced calcium release from the endoplamic reticulum and cell migration
Maria Hatziapostolou, G. Koukos, C. Polytarchou, F. Kottakis +3 more
2011Science Signaling29 citations Open access
Semantic Scholar
Helicobacter pylori neutrophil activating protein as target for new drugs against H. pylori inflammation.
T. Choli-Papadopoulou, F. Kottakis, G. Papadopoulos, S. Pendás
2011World Journal of Gastroenterology26 citations Open access
Semantic Scholar
RETRACTED: The Downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 Axis and by Human Cytomegalovirus (HCMV) Associated Factors Allows the Activation of the HCMV Major IE Promoter and the Transition to Productive Infection
G. Sourvinos, A. Morou, Ioannis Sanidas, Ignea Codruta +5 more
2014PLoS Pathogens25 citations Open access
Semantic Scholar
Akt3 induces oxidative stress and DNA damage by activating the NADPH oxidase via phosphorylation of p47phox
C. Polytarchou, Maria Hatziapostolou, Tung-On Yau, Niki Christodoulou +4 more
2020Proceedings of the National Academy of Sciences of the United States of America24 citations Open access
Semantic Scholar
Arabino-Galactan Proteins from Pistacia lentiscus var. chia: isolation, characterization and biological function
F. Kottakis, F. Lamari, Christina N. Matragkou, G. Zachariadis +2 more
2008Amino Acids16 citations
Semantic Scholar
NRF2: Translating the Redox Code
K. S. Tummala, F. Kottakis, N. Bardeesy
2016Trends in Molecular Medicine10 citations Open access
Semantic Scholar
The C‐terminal Region of HPNAP Activates Neutrophils and Promotes Their Adhesion to Endothelial Cells
F. Kottakis, C. Befani, A. Asiminas, M. Kontou +2 more
2009Helicobacter9 citations
Semantic Scholar
Gene signatures from pancreatic cancer tumor and stromal cells predict disease outcome
F. Kottakis, N. Bardeesy
2015Nature Genetics5 citations
Semantic Scholar
Author Correction: LKB1 loss links serine metabolism to DNA methylation and tumorigenesis
F. Kottakis, Brandon Nicolay, Ahlima Roumane, R. Karnik +15 more
2019Nature2 citations Open access
Semantic Scholar
Targeting colon cancer metabolism through a long noncoding RNA.
Maria Hatziapostolou, Marina Koutsioumpa, F. Kottakis, D. Iliopoulos +1 more
20152 citations
Semantic Scholar
Abstract 3895: Tumor suppressor activity of the ERK/MAPK signaling: inhibition of cell reprogramming by degradation of specific proteins
X. Deschênes-Simard, F. Kottakis, Frédéric Lessard, Emmanuelle Saint-Germain +3 more
20142 citations
Semantic Scholar
Abstract 462: Hyperactivation of ERK/MAPK pathway reduces pancreatic cancer cells' proliferation and tumor progression through phosphoproteome reprogramming
Marie-Camille Rowell, X. Deschênes-Simard, B. Le Calvé, S. Lopes-Paciencia +4 more
2018Molecular and Cellular Biology / Genetics1 citations
Semantic Scholar
Abstract 2154: ERK/MAPK pathway inhibits tumorigenesis and cellular reprogramming of pancreatic cancer cells
B. Le Calvé, Xavier Deschenes-Ximard, F. Kottakis, V. Bourdeau +7 more
20151 citations
Semantic Scholar
Tu1996 Regulation of Colon Cancer Metabolism by a Long Non-Coding RNA
Maria Hatziapostolou, Marina Koutsioumpa, F. Kottakis, D. Hommes +3 more
20151 citations Open access
Semantic Scholar
Abstract 108: FGF-2 regulates cell proliferation, migration and angiogenesis through a novel NDY1/KDM2B-miR101-EZH2 pathway
F. Kottakis, C. Polytarchou, S. Kampranis, P. Tsichlis
20111 citations
Semantic Scholar
Abstract IA15: The consequences of pRb inactivation: insights from a proteomic analysis of Rb loss
Brandon Nicolay, P. Danielian, F. Kottakis, John D. Lapek +12 more
20160 citations
Semantic Scholar
Abstract B42: Metabolic changes, associated with loss of the tumor suppressor LKB1, promote tumorigenesis
F. Kottakis, Brandon Nicolay, Nagle M. Julia, M. Liesa +3 more
20150 citations
Semantic Scholar
Abstract 4777: A phosphoproteomics analysis reveals Akt isoform-specific signals that link RNA splicing to non-small cell lung cancer
Ioannis Sanidas, C. Polytarchou, Maria Hatziapostolou, Scott A. Ezell +7 more
20140 citations
Semantic Scholar
NDY1/KDM2B, EZH2 and JARID2 are selectively required for the infection of human foreskin fibroblasts with HCMV whereas the H3K27me3 demethylase JMJD3 inhibits viral infection.
G. Sourvinos, A. Morou, Ioannis Sanidas, Ignea Codruta +5 more
20140 citations Open access
Semantic Scholar
Abstract A09: Downregulation of PI3K signaling by high ERK activity prevents transformation by oncogenic RAS
X. Deschênes-Simard, F. Kottakis, Frédéric Lessard, N. Bardeesy +1 more
20130 citations
Semantic Scholar
LKB1 suppresses melanoma metastasis: the answer is YES
F. Kottakis, S. Gurumurthy, N. Bardeesy
20120 citations Open access
Semantic Scholar
Natural agents against neutrophil involvement in H.Pylori induced chronic gastritis
S. Pendás, F. Kottakis, A. Asiminas, M. Kontou +3 more
20100 citations
Semantic Scholar
Genetic Engineering of Bacterial and Eukaryotic Ribosomal Proteins for Investigation on Elongation Arrest of Nascent Polypeptides and Cell Differentiation
F. Leontiadou, Christina N. Matragkou, F. Kottakis, D. Kalpaxis +4 more
20040 citations
Semantic Scholar

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