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Samar S. Fatahala · SciRah

Researcher profile · Semantic Scholar

Samar S. Fatahala

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Samar S. Fatahala — researcher profile on SciRah

h-index: 13
Works: 37
Citations: 558

Most-cited papers

Synthesis and biological evaluation of some thio containing pyrrolo [2,3-d]pyrimidine derivatives for their anti-inflammatory and anti-microbial activities.
M. Mohamed, Rehab Kamel, Samar S. Fatahala
2010European journal of medicinal chemistry98 citations
Semantic Scholar
Synthesis and Kinetic Testing of Tetrahydropyrimidine‐2‐thione and Pyrrole Derivatives as Inhibitors of the Metallo‐β‐lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa
W. Hussein, Samar S. Fatahala, Z. M. Mohamed, R. McGeary +3 more
2012Chemical Biology and Drug Design55 citations Open access
Semantic Scholar
Synthesis of novel pyrroles and fused pyrroles as antifungal and antibacterial agents
Rania H. Abd El-Hameed, Amira I. Sayed, Shima Mahmoud Ali, Mohamed A. Mosa +2 more
2021Journal of Enzyme Inhibition and Medicinal Chemistry43 citations Open access
Semantic Scholar
New condensed pyrroles of potential biological interest syntheses and structure-activity relationship studies.
M. Mohamed, Rehab Kamel, Samar S. Fatahala
2011European journal of medicinal chemistry39 citations
Semantic Scholar
Synthesis and antimicrobial screening of some fused heterocyclic pyrroles.
M. Mohamed, A. Rashad, M. Zaki, Samar S. Fatahala
2005Acta Pharmaceutica39 citations
Semantic Scholar
Synthesis and Biological Evaluation of Some Pyrrolo[2,3‐d]pyrimidines
A. Rashad, M. Mohamed, M. Zaki, Samar S. Fatahala
2006Archiv der Pharmazie28 citations
Semantic Scholar
A promising anti-cancer and anti-oxidant agents based on the pyrrole and fused pyrrole: synthesis, docking studies and biological evaluation.
Samar S. Fatahala, E. Shalaby, S. E. Kassab, M. S. Mohamed
2015Anti-Cancer Agents in Medicinal Chemistry25 citations
Semantic Scholar
Design, synthesis, molecular modeling and biological evaluation of novel Benzoxazole-Benzamide conjugates via a 2-Thioacetamido linker as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers
I. Eissa, Radwan Elhaggar, Mohammed A. Dahab, Marwa F. Ahmed +5 more
2022Journal of Enzyme Inhibition and Medicinal Chemistry22 citations Open access
Semantic Scholar
Novel pyrrolopyrimidine derivatives: design, synthesis, molecular docking, molecular simulations and biological evaluations as antioxidant and anti-inflammatory agents
Amira I. Sayed, Y. Mansour, Mohamed A. Ali, O. Aly +4 more
2022Journal of Enzyme Inhibition and Medicinal Chemistry21 citations Open access
Semantic Scholar
Synthesis and evaluation of novel spiro derivatives for pyrrolopyrimidines as anti-hyperglycemia promising compounds
Samar S. Fatahala, Shahenda Mahgub, Heba Taha, R. H. Abd-El Hameed
2018Journal of Enzyme Inhibition and Medicinal Chemistry19 citations Open access
Semantic Scholar
Pyrrolopyrazoles; Synthesis, Evaluation and Pharmacological Screening as Antidepressant Agents.
Samar S. Fatahala, Shahira Nofal, Eman Mahmoud, R. El-Hameed
2019Medicinal chemistry17 citations
Semantic Scholar
Synthesis of novel calcium channel blockers with ACE2 inhibition and dual antihypertensive/anti-inflammatory effects: A possible therapeutic tool for COVID-19
Shahenda Mahgoub, Mohamed-I Kotb El-Sayed, M. El-Shehry, Samir Mohamed Awad +2 more
2021Bioorganic chemistry (Print)16 citations Open access
Semantic Scholar
Synthesis and Evaluation of Cytotoxic Activity of Some Pyrroles and Fused Pyrroles.
Samar S. Fatahala, M. Mohamed, M. Youns, R. H. Abd-El Hameed
2017Anti-Cancer Agents in Medicinal Chemistry15 citations
Semantic Scholar
Synthesis of Some Novel Benzimidazole Derivatives as Anticancer Agent, and Evaluation for CDK2 Inhibition Activity.
R. El-Hameed, Samar S. Fatahala, Amira I. Sayed
2021Medicinal chemistry13 citations
Semantic Scholar
Synthesis of Novel 2-Thiouracil-5-Sulfonamide Derivatives as Potent Inducers of Cell Cycle Arrest and CDK2A Inhibition Supported by Molecular Docking
Samar S. Fatahala, Amira I. Sayed, Shahenda Mahgoub, Heba Taha +4 more
2021International Journal of Molecular Sciences13 citations Open access
Semantic Scholar
Synthesis and Structure Activity Relationship of Some Indole Derivatives as Potential Anti-inflammatory Agents.
Samar S. Fatahala, M. Khedr, M. S. Mohamed
2017Acta Chimica Slovenica12 citations Open access
Semantic Scholar
Novel N-Arylmethyl-aniline/chalcone hybrids as potential VEGFR inhibitors: synthesis, biological evaluations, and molecular dynamic simulations
Hesham Haffez, Nosaiba A. Elsayed, Marwa F. Ahmed, Samar S. Fatahala +8 more
2023Journal of Enzyme Inhibition and Medicinal Chemistry11 citations Open access
Semantic Scholar
Synthesis Strategies and Medicinal Value of Pyrrole and its Fused Heterocyclic Compounds.
Samar S. Fatahala, M. Mohamed, Jaqueline Youssef Sabry, Yara E. Mansour
2022Medicinal chemistry10 citations
Semantic Scholar
Novel hit of DPP-4Is as promising antihyperglycemic agents with dual antioxidant/anti-inflammatory effects for type 2 diabetes with/without COVID-19
Shahenda Mahgoub, Samar S. Fatahala, Amira I. Sayed, Hanaa B. Atya +5 more
2022Bioorganic chemistry (Print)10 citations Open access
Semantic Scholar
Synthesis and Evaluation of Some Uracil Nucleosides as Promising Anti-Herpes Simplex Virus 1 Agents
S. Awad, Shimaa M. Ali, Y. Mansour, Samar S. Fatahala
2021Molecules10 citations Open access
Semantic Scholar
Amino acid-modified chalcone derivatives with in vitro and in vivo efficacy against colon cancer.
Radwan Elhaggar, Reem I. Alsantali, Ahmed M. Aboshanab, M. A. Alkabbani +3 more
2025European journal of medicinal chemistry9 citations
Semantic Scholar
Pyrimidines as Anticancer and Antiviral: Synthesis & Reactions (A Review)
Samar S. Fatahala, M. Mohamed, M. Khodair, Rania H. Abd El-Hameed
2022Journal of Advanced Pharmacy Research7 citations Open access
Semantic Scholar
Design, synthesis, molecular modeling, in vitro and in vivo biological evaluation of potent anthranilamide derivatives as dual P-glycoprotein and CYP3A4 inhibitors.
A. Said, Y. Mansour, Radwa R. Soliman, Ridwan Islam +1 more
2024European journal of medicinal chemistry6 citations Open access
Semantic Scholar
Pyrrolopyrimidine derivatives as dual COX-2/ACE2 inhibitors: design, synthesis, and anti-inflammatory evaluation
Hala Afifi, Samar S. Fatahala, Rania H. Abd El-Hameed, Shahenda Mahgoub +5 more
2026Frontiers in Molecular Biosciences4 citations
Semantic Scholar
Synthesis, Anti-Cancer Activity, Cell Cycle Arrest, Apoptosis Induction, and Docking Study of Fused Benzo[h]chromeno[2,3-d]pyrimidine on Human Breast Cancer Cell Line MCF-7
Zainab M. Khoder, M. Mohamed, S. Awad, Amal F. Gharib +4 more
2024Molecules3 citations Open access
Semantic Scholar
Novel Cyanopyrimidine Derivatives as Potential Anticancer Agents
Rania H. Abd El-Hameed, O. Aly, Mariem E. Mohamed, Amal F. Gharib +5 more
2025Molecules2 citations Open access
Semantic Scholar
Synthesis, anti-cancer evaluation and in vitro study of some novel pyrrolo-pyrimidine scaffolds
Mariem El Saeed Mohamed, Samar S. Fatahala, Rania H. Abd El-Hameed, Hanaa B. Atya +3 more
2025Egyptian Journal of Chemistry2 citations
Semantic Scholar
Pyrimidine as a naturally occurring bioactive ring and its importance in different arenas
Mariem El Saeed Mohamed, Samar S. Fatahala, Rania H. Abd El-Hameed, M. Mohamed
2024Egyptian Journal of Chemistry2 citations
Semantic Scholar
Design and Synthesis of Some N-4-Substituted Pyrrolopyrimidines with Promising Anticancer Effects
Jaqueline Y. Riad, M. Mohamed, Samar S. Fatahala, Yara E. Mansour
2023Egyptian Journal of Chemistry2 citations Open access
Semantic Scholar
Retrosynthesis analysis; a way to design a retrosynthesis map for Pyridine and pyrimidine ring
Samar S. Fatahala
20172 citations Open access
Semantic Scholar
WITHDRAWN: Synthesis and biological evaluation of some novel Pyrrolo[2, 3-d]pyrimidine derivatives.
M. Mohamed, Rehab Kamel, Samar S. Fatahala
2010Bioorganic & Medicinal Chemistry Letters2 citations
Semantic Scholar
Pyrroles and fused pyrroles: synthesis strategies and medicinal values
Yara E. Mansour, M. Mohamed, Samar S. Fatahala, Jaqueline Y. Riad
2026Chemické zvesti1 citations
Semantic Scholar
New Condensed Pyrroles of Potential Biological Interest Syntheses and Structure—Activity Relationship Studies.
M. Mohamed, Rehab Kamel, Samar S. Fatahala
20111 citations
Semantic Scholar
Design, Synthesis, and Mechanistic Biological Evaluation of a Multifunctional 2-Furanone Scaffold Targeting Hyperglycemia, Inflammation, and Regulated Cell Death in Experimental Type 2 Diabetes
H. El-Shanbaky, Basma Elsayed Shetta, Shady Estfanos, M. Mohamed +3 more
2026Journal of Molecular Structure0 citations
Semantic Scholar
Recent Advances in 2(3H)-Furanone Chemistry and Its Hydrazide Derivative: Synthesis and Reactions
H. El-Shanbaky, Rania Abdelhameed, M. Mohamed, Samar S. Fatahala
2025Egyptian Journal of Chemistry0 citations
Semantic Scholar
Novel hit of DPP-4Is as promising antihyperglycemic agents with dual antioxidant/anti-inflammatory effects for type 2 diabetes with/without COVID-19 Bioorganic Chemistry
Shahenda Mahgoub, Samar S. Fatahala, Amira I. Sayed, Hanaa B. Atya +5 more
20220 citations
Semantic Scholar
Novel hit of DPP-4Is as promising antihyperglycemic agents with dual antioxidant/anti-inflammatory effects for type 2 diabetes with/without COVID-19 Bioorganic Chemistry
Shahenda Mahgoub, Samar S. Fatahala, Amira I. Sayed, Hanaa B. Atya +5 more
20220 citations
Semantic Scholar

Frequent co-authors

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Rania H. Abd El-Hameed×13
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Rania H. Abd El-Hameed — researcher profile on SciRah
M. Mohamed×10
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M. Mohamed — researcher profile on SciRah
Amira I. Sayed×9
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Amira I. Sayed — researcher profile on SciRah
Heba Taha×7
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Heba Taha — researcher profile on SciRah

Shahenda Mahgoub

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Shahenda Mahgoub — researcher profile on SciRah

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M. Mohamed — researcher profile on SciRah

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S. Awad — researcher profile on SciRah

M. El-Shehry×5

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M. El-Shehry — researcher profile on SciRah

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Rehab Kamel — researcher profile on SciRah

Zainab M. Khoder×4

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Zainab M. Khoder — researcher profile on SciRah

Radwan Elhaggar×4

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Radwan Elhaggar — researcher profile on SciRah

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Y. Mansour — researcher profile on SciRah