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D. Clemens · SciRah

Researcher profile · Semantic Scholar

D. Clemens

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D. Clemens — researcher profile on SciRah

h-index: 24
Works: 46
Citations: 2,326

Most-cited papers

Virulent and Avirulent Strains of Francisella tularensis Prevent Acidification and Maturation of Their Phagosomes and Escape into the Cytoplasm in Human Macrophages
D. Clemens, Bai-Yu Lee, M. Horwitz
2004Infection and Immunity387 citations Open access
Semantic Scholar
Francisella tularensis Enters Macrophages via a Novel Process Involving Pseudopod Loops
D. Clemens, Bai-Yu Lee, M. Horwitz
2005Infection and Immunity229 citations Open access
Semantic Scholar
Targeted Intracellular Delivery of Antituberculosis Drugs to Mycobacterium tuberculosis-Infected Macrophages via Functionalized Mesoporous Silica Nanoparticles
D. Clemens, Bai-Yu Lee, Min Xue, Courtney R. Thomas +5 more
2012Antimicrobial Agents and Chemotherapy213 citations Open access
Semantic Scholar
Massively Parallel Delivery of Large-Sized Cargo into Mammalian Cells with Light Pulses
Yi-Chien Wu, Ting-Hsiang Wu, D. Clemens, Bai-Yu Lee +4 more
2015Nature Methods164 citations Open access
Semantic Scholar
Mesoporous Silica Nanoparticles with pH-Sensitive Nanovalves for Delivery of Moxifloxacin Provide Improved Treatment of Lethal Pneumonic Tularemia.
Zilu Li, D. Clemens, Bai-Yu Lee, B. Dillon +2 more
2015ACS Nano117 citations Open access
Semantic Scholar
Output-driven feedback system control platform optimizes combinatorial therapy of tuberculosis using a macrophage cell culture model
Aleidy Silva, Bai-Yu Lee, D. Clemens, Theodore Kee +3 more
2016Proceedings of the National Academy of Sciences of the United States of America88 citations Open access
Semantic Scholar
Francisella tularensis Phagosomal Escape Does Not Require Acidification of the Phagosome
D. Clemens, Bai-Yu Lee, M. Horwitz
2009Infection and Immunity88 citations Open access
Semantic Scholar
Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses
E. J. Gillespie, Chi-Lee C Ho, K. Balaji, D. Clemens +16 more
2013Proceedings of the National Academy of Sciences of the United States of America87 citations Open access
Semantic Scholar
Redox-Triggered Release of Moxifloxacin from Mesoporous Silica Nanoparticles Functionalized with Disulfide Snap-Tops Enhances Efficacy Against Pneumonic Tularemia in Mice.
Bai-Yu Lee, Zilu Li, D. Clemens, B. Dillon +3 more
2016Small75 citations Open access
Semantic Scholar
pH-Responsive Isoniazid-Loaded Nanoparticles Markedly Improve Tuberculosis Treatment in Mice
A. A. Hwang, Bai-Yu Lee, D. Clemens, B. Dillon +2 more
2015Small75 citations Open access
Semantic Scholar
The Mycobacterium bovis Bacille Calmette-Guérin Phagosome Proteome*
Bai-Yu Lee, D. Jethwaney, B. Schilling, D. Clemens +2 more
2009Molecular & Cellular Proteomics75 citations Open access
Semantic Scholar
The Francisella Type VI Secretion System
D. Clemens, Bai-Yu Lee, M. Horwitz
2018Frontiers in Cellular and Infection Microbiology74 citations Open access
Semantic Scholar
Identification, Recombinant Expression, Immunolocalization in Macrophages, and T-Cell Responsiveness of the Major Extracellular Proteins of Francisella tularensis
Bai-Yu Lee, M. Horwitz, D. Clemens
2006Infection and Immunity65 citations
Semantic Scholar
A Pathogen-Specific Cargo Delivery Platform Based on Mesoporous Silica Nanoparticles.
Bastian Ruehle, D. Clemens, Bai-Yu Lee, M. Horwitz +1 more
2017Journal of the American Chemical Society64 citations Open access
Semantic Scholar
Facile Strategy Enabling Both High Loading and High Release Amounts of the Water-Insoluble Drug Clofazimine Using Mesoporous Silica Nanoparticles.
Wei Chen, Chi-An Cheng, Bai-Yu Lee, D. Clemens +3 more
2018ACS Applied Materials and Interfaces60 citations Open access
Semantic Scholar
Recombinant Attenuated Listeria monocytogenes Vaccine Expressing Francisella tularensis IglC Induces Protection in Mice Against Aerosolized Type A F. tularensis
Qing-Mei Jia, Bai-Yu Lee, D. Clemens, R. Bowen +1 more
2009Vaccine60 citations Open access
Semantic Scholar
Drug regimens identified and optimized by output-driven platform markedly reduce tuberculosis treatment time
Bai-Yu Lee, D. Clemens, Aleidy Silva, B. Dillon +5 more
2017Nature Communications57 citations Open access
Semantic Scholar
The Mycobacterium tuberculosis Phagosome in Human Macrophages Is Isolated from the Host Cell Cytoplasm
D. Clemens, Bai-Yu Lee, M. Horwitz
2002Infection and Immunity53 citations Open access
Semantic Scholar
Renin in rat and mouse brain: immunohistochemical identification and localization.
T. Inagami, M. Celio, D. Clemens, D. Lau +3 more
1980Clinical science50 citations
Semantic Scholar
Intracellular Photothermal Delivery for Suspension Cells Using Sharp Nanoscale Tips in Microwells.
Tianxing Man, Xiong-Feng Zhu, Y. Chow, Emma R. Dawson +12 more
2019ACS Nano44 citations Open access
Semantic Scholar
Artificial intelligence enabled parabolic response surface platform identifies ultra-rapid near-universal TB drug treatment regimens comprising approved drugs
D. Clemens, Bai-Yu Lee, Aleidy Silva, B. Dillon +5 more
2019PLoS ONE34 citations Open access
Semantic Scholar
Renin in anterior pituitary, pineal, and neuronal cells of mouse brain. immunohistochemical localization
M. Celio, D. Clemens, T. Inagami
198029 citations Open access
Semantic Scholar
O-Antigen-Deficient Francisella tularensis Live Vaccine Strain Mutants Are Ingested via an Aberrant Form of Looping Phagocytosis and Show Altered Kinetics of Intracellular Trafficking in Human Macrophages
D. Clemens, Bai-Yu Lee, M. Horwitz
2011Infection and Immunity28 citations Open access
Semantic Scholar
Conservation of CD1 Intracellular Trafficking Patterns Between Mammalian Species1
C. Dascher, K. Hiromatsu, X. Xiong, M. Sugita +10 more
2002Journal of Immunology27 citations Open access
Semantic Scholar
Ultra-rapid near universal TB drug regimen identified via parabolic response surface platform cures mice of both conventional and high susceptibility
Bai-Yu Lee, D. Clemens, Aleidy Silva, B. Dillon +4 more
2018PLoS ONE18 citations Open access
Semantic Scholar
Generation of angiotensins in cultured pheochromocytoma cells.
T. Okamura, D. Clemens, T. Inagami
1984Neuroscience Letters15 citations
Semantic Scholar
Identification, Characterization and Evidence for Intraneuronal Function of Renin in the Brain and Neuroblastoma Cells
T. Inagami, T. Okamura, S. Hirose, D. Clemens +4 more
198212 citations
Semantic Scholar
Nanoparticle formulation of moxifloxacin and intramuscular route of delivery improve antibiotic pharmacokinetics and treatment of pneumonic tularemia in a mouse model
D. Clemens, Bai-Yu Lee, Sheba Plamthottam, Michael V. Tullius +6 more
2018ACS Infectious Diseases11 citations Open access
Semantic Scholar
Atomic Structure of Francisella T6SS Central Spike Reveals Unique α-Helical Lid and a Putative Cargo
Xue Yang, D. Clemens, Bai-Yu Lee, Yan-Xiang Cui +2 more
2019Structure8 citations Open access
Semantic Scholar
Tuberculosis: pH-Responsive Isoniazid-Loaded Nanoparticles Markedly Improve Tuberculosis Treatment in Mice (Small 38/2015).
A. A. Hwang, Bai-Yu Lee, D. Clemens, B. Dillon +2 more
2015Small7 citations Open access
Semantic Scholar
Human alveolar lining fluid from the elderly promotes Mycobacterium tuberculosis growth in alveolar epithelial cells and bacterial translocation into the cytosol
Angélica M. Olmo-Fontánez, Julia M. Scordo, Andreu Garcia-Vilanova, D. Maselli +6 more
2021bioRxiv5 citations Open access
Semantic Scholar
AI-Enabled Parabolic Response Surface Approach Identifies Ultra Short-Course Near-Universal TB Drug Regimens
M. Horwitz, D. Clemens, Bai-Yu Lee
2019Advances in Therapy5 citations Open access
Semantic Scholar
Photothermal nanoblades for delivery of large-sized cargo into mammalian cells at high throughput
Yi-Chien Wu, T. Santra, Ting-Hsiang Wu, D. Clemens +5 more
20162016 IEEE 16th International Conference on Nanotechnology (IEEE-NANO)1 citations Open access
Semantic Scholar
Tunable dielectrophoresis for sheathless 3D focusing
Yu-Chun Kung, D. Clemens, Bai-Yu Lee, P. Chiou
2015IEEE/LEOS International Conference on Optical MEMS1 citations
Semantic Scholar
Structure of PdpA-VgrG Complex, Lidless
X. Yang, D. Clemens, Bai-Yu Lee, Yan-Xiang Cui +2 more
20190 citations
Semantic Scholar
Structure of Francisella PdpA-VgrG Complex, half-lidded
X. Yang, D. Clemens, B.-Y. Lee, Y. Cui +2 more
20190 citations
Semantic Scholar
Structure of Francisella PdpA-VgrG Complex, Lidded
X. Yang, D. Clemens, Bai-Yu Lee, Yan-Xiang Cui +2 more
20190 citations
Semantic Scholar
The interaction of BFSP1 and its proteolytically derived fragments with cell membranes
R. Quinlan, Antal Tapodi, D. Clemens, K. Németh-Cahalan +5 more
20160 citations
Semantic Scholar
Intracellular Delivery: Redox-Triggered Release of Moxifloxacin from Mesoporous Silica Nanoparticles Functionalized with Disulfide Snap-Tops Enhances Efficacy Against Pneumonic Tularemia in Mice (Small 27/2016).
Bai-Yu Lee, Zilu Li, D. Clemens, B. Dillon +3 more
2016Small0 citations Open access
Semantic Scholar
CryoEM structure of a type VI secretion system
D. Clemens, P. Ge, Bai-Yu Lee, M. Horwitz +1 more
20150 citations
Semantic Scholar
Wärmekollektor mit montageplatte
D. Clemens, David W. Gailus
20020 citations
Semantic Scholar
Collecteur de chaleur avec plaque de montage
D. Clemens, David W. Gailus
20020 citations
Semantic Scholar
Legionella pneumophila and Mycobacterium tuberculosis: Two pathways through the mononuclear phagocyte
M. Horwitz, D. Clemens
19990 citations
Semantic Scholar
Characterization of the Mycobacterium tubercolosis phagosome
D. Clemens
19960 citations
Semantic Scholar
Intracellular Actions of Renin
T. Inagami, J. Mckenzie, K. Pandey, M. Nakamaru +4 more
19840 citations
Semantic Scholar
Molecular characterization of inactive renin: complete purification of prorenin in hog kidney and isolation of inactive renin from neuroblastoma cells: evidence for 2 different types of inactive renin.
T. Inagami, Y. Takii, T. Inagaki, D. Clemens +3 more
1982Clinical and Experimental Hypertension Part A Theory and Practice0 citations
Semantic Scholar

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