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R. Quinlan · SciRah

Researcher profile · Semantic Scholar

R. Quinlan

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R. Quinlan — researcher profile on SciRah

h-index: 51
Works: 202
Citations: 7,107

Most-cited papers

Functions of the intermediate filament cytoskeleton in the eye lens.
Shuhua Song, A. Landsbury, R. Dahm, Yi-Zhi Liu +2 more
2009Journal of Clinical Investigation171 citations Open access
Semantic Scholar
The growing world of small heat shock proteins: from structure to functions
S. Carra, S. Alberti, Patrick A. Arrigo, J. Benesch +26 more
2017Cell stress & chaperones (Print)169 citations Open access
Semantic Scholar
Ionizing radiation induced cataracts: Recent biological and mechanistic developments and perspectives for future research.
E. Ainsbury, S. Barnard, S. Bright, C. Dalke +8 more
2016Mutation research141 citations
Semantic Scholar
Oligomers of Mutant Glial Fibrillary Acidic Protein (GFAP) Inhibit the Proteasome System in Alexander Disease Astrocytes, and the Small Heat Shock Protein αB-Crystallin Reverses the Inhibition*
Guomei Tang, M. Perng, S. Wilk, R. Quinlan +1 more
2010Journal of Biological Chemistry101 citations Open access
Semantic Scholar
Glial fibrillary acidic protein filaments can tolerate the incorporation of assembly-compromised GFAP-delta, but with consequences for filament organization and alphaB-crystallin association.
M. Perng, Shu-Fang Wen, Terry Gibbon, J. Middeldorp +3 more
2008Molecular Biology of the Cell99 citations Open access
Semantic Scholar
Inherited cataracts: molecular genetics, clinical features, disease mechanisms and novel therapeutic approaches
V. Berry, M. Georgiou, K. Fujinami, R. Quinlan +2 more
2020British Journal of Ophthalmology72 citations Open access
Semantic Scholar
Cataractogenic load - A concept to study the contribution of ionizing radiation to accelerated aging in the eye lens.
A. Uwineza, A. Kalligeraki, N. Hamada, M. Jarrín +1 more
2019Mutation research67 citations Open access
Semantic Scholar
Alexander Disease: A Genetic Disorder of Astrocytes
M. Brenner, J. Goldman, R. Quinlan, A. Messing
200962 citations
Semantic Scholar
Caspase cleavage of GFAP produces an assembly-compromised proteolytic fragment that promotes filament aggregation
Mei-Hsuan Chen, Tracy L. Hagemann, R. Quinlan, A. Messing +1 more
2013ASN Neuro60 citations Open access
Semantic Scholar
Site-specific phosphorylation and caspase cleavage of GFAP are new markers of Alexander disease severity
Rachel A. Battaglia, Adriana S. Beltrán, Samed Delic, R. Dumitru +12 more
2019eLife55 citations Open access
Semantic Scholar
The specificity of the interaction between αB-crystallin and desmin filaments and its impact on filament aggregation and cell viability
Jayne L. Elliott, Ming Der Perng, A. Prescott, K. Jansen +2 more
2013Philosophical Transactions of the Royal Society B: Biological Sciences55 citations Open access
Semantic Scholar
The functional roles of the unstructured N- and C-terminal regions in αB-crystallin and other mammalian small heat-shock proteins
J. Carver, Aidan B. Grosas, H. Ecroyd, R. Quinlan
2017Cell stress & chaperones (Print)54 citations Open access
Semantic Scholar
Nonlinear ionizing radiation-induced changes in eye lens cell proliferation, cyclin D1 expression and lens shape
E. Markiewicz, S. Barnard, J. Haines, Margaret R. Coster +7 more
2015Open Biology54 citations Open access
Semantic Scholar
Radiation protection of the eye lens in medical workers—basis and impact of the ICRP recommendations
S. Barnard, E. Ainsbury, R. Quinlan, S. Bouffler
2016British Journal of Radiology53 citations Open access
Semantic Scholar
Homeostasis in the vertebrate lens: mechanisms of solute exchange
R. Dahm, J. van Marle, R. Quinlan, A. Prescott +1 more
2011Philosophical Transactions of the Royal Society B: Biological Sciences51 citations Open access
Semantic Scholar
Intermediate filament transcription in astrocytes is repressed by proteasome inhibition
J. Middeldorp, W. Kamphuis, J. Sluijs, Dalila Achoui +8 more
2009The FASEB Journal51 citations Open access
Semantic Scholar
A rim-and-spoke hypothesis to explain the biomechanical roles for cytoplasmic intermediate filament networks
R. Quinlan, Nicole Schwarz, R. Windoffer, Christine A. Richardson +4 more
2017Journal of Cell Science50 citations Open access
Semantic Scholar
Inverse dose-rate effect of ionising radiation on residual 53BP1 foci in the eye lens
S. Barnard, R. McCarron, J. Moquet, R. Quinlan +1 more
2019Scientific Reports45 citations Open access
Semantic Scholar
Alexander disease causing mutations in the C-terminal domain of GFAP are deleterious both to assembly and network formation with the potential to both activate caspase 3 and decrease cell viability
Yi-Song Chen, Suh-Ciuan Lim, Mei-Hsuan Chen, R. Quinlan +1 more
2011Experimental Cell Research45 citations Open access
Semantic Scholar
The genetic landscape of crystallins in congenital cataract
V. Berry, A. Ionides, Nikolas Pontikos, M. Georgiou +5 more
2020Orphanet Journal of Rare Diseases41 citations Open access
Semantic Scholar
A cell polarity protein aPKCλ is required for eye lens formation and growth
Y. Sugiyama, K. Akimoto, M. Robinson, S. Ohno +1 more
2009Developmental Biology40 citations Open access
Semantic Scholar
Regulation of contractility by Hsp27 and Hic-5 in rat mesenteric small arteries.
Radhika Srinivasan, S. Forman, R. Quinlan, Jacqueline Ohanian +1 more
2008American Journal of Physiology. Heart and Circulatory Physiology38 citations Open access
Semantic Scholar
Insights into the biochemical and biophysical mechanisms mediating the longevity of the transparent optics of the eye lens
R. Quinlan, John I. Clark
2022Journal of Biological Chemistry37 citations Open access
Semantic Scholar
A gradient of matrix-bound FGF-2 and perlecan is available to lens epithelial cells
Weiju Wu, F. Tholozan, M. Goldberg, L. Bowen +2 more
2014Experimental Eye Research32 citations Open access
Semantic Scholar
Chaperones: needed for both the good times and the bad times
R. Quinlan, R. Ellis
2013Philosophical Transactions of the Royal Society B: Biological Sciences32 citations Open access
Semantic Scholar
Multiple Sites in αB-Crystallin Modulate Its Interactions with Desmin Filaments Assembled In Vitro
Scott A. Houck, A. Landsbury, John I. Clark, R. Quinlan
2011PLoS ONE32 citations Open access
Semantic Scholar
αB-crystallin is a sensor for assembly intermediates and for the subunit topology of desmin intermediate filaments
Sarika Sharma, Gloria M. Conover, Jayne L. Elliott, Ming Der Perng +2 more
2017Cell stress & chaperones (Print)25 citations Open access
Semantic Scholar
A dimensionless ordered pull-through model of the mammalian lens epithelium evidences scaling across species and explains the age-dependent changes in cell density in the human lens
Jun-Jie Wu, Weiju Wu, F. Tholozan, C. Saunter +2 more
2015Journal of the Royal Society Interface25 citations Open access
Semantic Scholar
MAPKAPK-2 modulates p38-MAPK localization and small heat shock protein phosphorylation but does not mediate the injury associated with p38-MAPK activation during myocardial ischemia
Diana A Gorog, R. Jabr, M. Tanno, N. Sarafraz +11 more
2009Cell stress & chaperones (Print)25 citations Open access
Semantic Scholar
Small molecules, both dietary and endogenous, influence the onset of lens cataracts
S. Barnes, R. Quinlan
2016Experimental Eye Research22 citations Open access
Semantic Scholar
BFSP1 C-terminal domains released by post-translational processing events can alter significantly the calcium regulation of AQP0 water permeability
Antal Tapodi, Daniel M. Clemens, A. Uwineza, M. Jarrín +8 more
2019Experimental Eye Research20 citations Open access
Semantic Scholar
Stochastically determined directed movement explains the dominant small‐scale mitochondrial movements within non‐neuronal tissue culture cells
Christopher D. Saunter, Ming Der Perng, G. Love, R. Quinlan
2009FEBS Letters20 citations Open access
Semantic Scholar
A new dawn for cataracts
R. Quinlan
2015Science19 citations
Semantic Scholar
Heat shock proteins are differentially expressed in brain and spinal cord: implications for multiple sclerosis
R. Gorter, E. Nutma, M.-C. Jahrei, J. D. de Jonge +5 more
2018Clinical and Experimental Immunology16 citations Open access
Semantic Scholar
Sub-nanometre mapping of the aquaporin-water interface using multifrequency atomic force microscopy.
M. Ricci, R. Quinlan, Kislon Voïtchovsky
2017Soft Matter16 citations Open access
Semantic Scholar
On the Nature of Murine Radiation-Induced Subcapsular Cataracts: Optical Coherence Tomography-Based Fine Classification, In Vivo Dynamics and Impact on Visual Acuity
D. Pawliczek, H. Fuchs, V. Gailus-Durner, M. D. de Angelis +3 more
2021Radiation Research15 citations Open access
Semantic Scholar
Dotting the eyes: mouse strain dependency of the lens epithelium to low dose radiation-induced DNA damage
S. Barnard, J. Moquet, S. Lloyd, Michele Ellender +2 more
2018International Journal of Radiation Biology15 citations
Semantic Scholar
γ-Crystallin redox–detox in the lens
R. Quinlan, P. Hogg
2018Journal of Biological Chemistry14 citations Open access
Semantic Scholar
Glial Fibrillary Acidic Protein Filaments Can Tolerate the Incorporation of Assembly-compromised GFAP- , but with Consequences for Filament Organization and B-Crystallin Association
M. Perng, Shu-Fang Wen, Terry Gibbon, J. Middeldorp +3 more
200814 citations
Semantic Scholar
Lens Epithelial Cell Proliferation in Response to Ionizing Radiation
S. Barnard, A. Uwineza, A. Kalligeraki, R. McCarron +3 more
2021Radiation Research13 citations
Semantic Scholar
Three-dimensional data capture and analysis of intact eye lenses evidences emmetropia-associated changes in epithelial cell organization
A. Kalligeraki, Archie Isted, M. Jarrín, A. Uwineza +5 more
2020Scientific Reports13 citations Open access
Semantic Scholar
The lipidation profile of aquaporin-0 correlates with the acyl composition of phosphoethanolamine lipids in lens membranes.
Vian S. Ismail, J. Mosely, Antal Tapodi, R. Quinlan +1 more
2016Biochimica et Biophysica Acta13 citations Open access
Semantic Scholar
Purification of Protein Chaperones and Their Functional Assays with Intermediate Filaments.
M. Perng, Yu-Shan Huang, R. Quinlan
2016Methods in Enzymology12 citations
Semantic Scholar
Biophysical dissection of schistosome septins: Insights into oligomerization and membrane binding.
A. E. Zeraik, M. Staykova, M. Fontes, Indrė Nemuraitė +3 more
2016Biochimie11 citations Open access
Semantic Scholar
The lens of the eye: exposures in the UK medical sector and mechanistic studies of radiation effects
S. Bouffler, S. Peters, P. Gilvin, K. Slack +7 more
2015Annals of the ICRP10 citations Open access
Semantic Scholar
Evaluation of cataract formation in fish exposed to environmental radiation at Chernobyl and Fukushima.
A. Lerebours, J. Regini, R. Quinlan, T. Wada +15 more
2023Science of the Total Environment9 citations Open access
Semantic Scholar
Non-invasive in vivo quantification of the developing optical properties and graded index of the embryonic eye lens using SPIM.
L. Young, M. Jarrín, C. Saunter, R. Quinlan +1 more
2018Biomedical Optics Express9 citations Open access
Semantic Scholar
In vivo, Ex Vivo, and In Vitro Approaches to Study Intermediate Filaments in the Eye Lens.
M. Jarrín, L. Young, Weiju Wu, J. Girkin +1 more
2016Methods in Enzymology9 citations
Semantic Scholar
Pathogenic variants in the CYP21A2 gene cause isolated autosomal dominant congenital posterior polar cataracts
V. Berry, Nikolas Pontikos, A. Ionides, A. Kalitzeos +2 more
2021Ophthalmic Genetics8 citations Open access
Semantic Scholar
Variants in PAX6, PITX3 and HSF4 causing autosomal dominant congenital cataracts
V. Berry, A. Ionides, Nikolas Pontikos, A. Moore +2 more
2021Eye8 citations Open access
Semantic Scholar

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