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Winnie Luu · SciRah

Researcher profile · Semantic Scholar

Winnie Luu

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Winnie Luu — researcher profile on SciRah

h-index: 15
Works: 27
Citations: 1,354

Most-cited papers

The Akt-SREBP nexus: cell signaling meets lipid metabolism.
J. Krycer, Laura J. Sharpe, Winnie Luu, Andrew J. Brown
2010Trends in endocrinology and metabolism344 citations
Semantic Scholar
DHCR7: A vital enzyme switch between cholesterol and vitamin D production.
A. V. Prabhu, Winnie Luu, Dianfan Li, Laura J. Sharpe +1 more
2016Progress in lipid research162 citations
Semantic Scholar
Oxysterols: Old Tale, New Twists.
Winnie Luu, Laura J. Sharpe, Isabelle M. Capell-Hattam, I. Gelissen +1 more
2016Annual Review of Pharmacology and Toxicology144 citations Open access
Semantic Scholar
Cholesterol-mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis*
Laura J. Sharpe, A. V. Prabhu, Winnie Luu, Andrew J. Brown
2016Journal of Biological Chemistry135 citations Open access
Semantic Scholar
The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally[S]
Winnie Luu, Gene Hart-Smith, Laura J. Sharpe, Andrew J. Brown
2015Journal of Lipid Research86 citations Open access
Semantic Scholar
Akt acutely activates the cholesterogenic transcription factor SREBP-2.
Winnie Luu, Laura J. Sharpe, J. Stevenson, Andrew J. Brown
2012Biochimica et Biophysica Acta75 citations Open access
Semantic Scholar
Signaling regulates activity of DHCR24, the final enzyme in cholesterol synthesis[S]
Winnie Luu, Eser J. Zerenturk, Ika Kristiana, M. Bucknall +2 more
2014Journal of Lipid Research70 citations Open access
Semantic Scholar
Akt Phosphorylates Sec24: New Clues into the Regulation of ER‐to‐Golgi Trafficking
Laura J. Sharpe, Winnie Luu, Andrew J. Brown
2011Traffic : the International Journal of Intracellular Transport59 citations Open access
Semantic Scholar
Cholesterol increases protein levels of the E3 ligase MARCH6 and thereby stimulates protein degradation
Laura J. Sharpe, Vicky Howe, Nicola A. Scott, Winnie Luu +4 more
2018Journal of Biological Chemistry46 citations Open access
Semantic Scholar
The role of signalling in cellular cholesterol homeostasis
Winnie Luu, Laura J. Sharpe, Ingrid C. Gelissen, Andrew J. Brown
2013IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology46 citations Open access
Semantic Scholar
Squalene mono-oxygenase, a key enzyme in cholesterol synthesis, is stabilized by unsaturated fatty acids.
J. Stevenson, Winnie Luu, Ika Kristiana, Andrew J. Brown
2014Biochemical Journal43 citations
Semantic Scholar
Phosphorylation regulates activity of 7-dehydrocholesterol reductase (DHCR7), a terminal enzyme of cholesterol synthesis.
A. V. Prabhu, Winnie Luu, Laura J. Sharpe, Andrew J. Brown
2017Journal of Steroid Biochemistry and Molecular Biology32 citations
Semantic Scholar
The cholesterol synthesis enzyme lanosterol 14α-demethylase is post-translationally regulated by the E3 ubiquitin ligase MARCH6
Nicola A. Scott, Laura J. Sharpe, Isabelle M. Capell-Hattam, Samuel J. Gullo +2 more
2020Biochemical Journal29 citations Open access
Semantic Scholar
Cholesterol synthesis enzyme SC4MOL is fine-tuned by sterols and targeted for degradation by the E3 ligase MARCHF6
Lydia Qian, Nicola A. Scott, Isabelle M. Capell-Hattam, Eliza Draper +4 more
2023Journal of Lipid Research22 citations Open access
Semantic Scholar
Cholesterol through the Looking Glass
Ika Kristiana, Winnie Luu, J. Stevenson, S. Cartland +4 more
2012Journal of Biological Chemistry19 citations Open access
Semantic Scholar
A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity
Alex J. McCann, Jieqiong Lou, Mehdi Moustaqil, Matthew S. Graus +12 more
2020bioRxiv15 citations Open access
Semantic Scholar
The blood vasculature instructs lymphatic patterning in a SOX7‐dependent manner
I. K. Chiang, Matthew S. Graus, Nils Kirschnick, Tara Davidson +17 more
2023EMBO Journal10 citations Open access
Semantic Scholar
Manipulating Cholesterol Status Within Cells.
Winnie Luu, I. Gelissen, Andrew J. Brown
2017Methods in molecular biology10 citations
Semantic Scholar
Navigating the Shallows and Rapids of Cholesterol Synthesis Downstream of HMGCR.
Laura J. Sharpe, Vicky Howe, A. V. Prabhu, Winnie Luu +1 more
2015Journal of Nutritional Science and Vitaminology5 citations Open access
Semantic Scholar
Protein tyrosine phosphatase inhibition down-regulates ligand-induced ABCA1 expression.
Winnie Luu, Laura J. Sharpe, Andrew J. Brown
2013Atherosclerosis3 citations
Semantic Scholar
Measuring Activity of Cholesterol Synthesis Enzymes Using Gas Chromatography/Mass Spectrometry.
A. V. Prabhu, Winnie Luu, Andrew J. Brown
2017Methods in molecular biology1 citations
Semantic Scholar
Biophysical dissection of SOX18/NR2F2 transcriptional antagonism reveals mechanisms of venous differentiation and drug action in vascular malformation
Matthew S. Graus, Sawan Kumar Jha, Jieqiong Lou, Annegret Holm +14 more
2025bioRxiv0 citations
Semantic Scholar
The blood vasculature instructs lymphatics patterning in a SOX7 dependent manner
I. K. Chiang, Winnie Luu, K. Jiang, Nils Kirschnick +13 more
2021bioRxiv0 citations Open access
Semantic Scholar
リン酸化は7-デヒドロコレステロールレダクターゼ(DHCR7),コレステロール合成の最終酵素の活性を調節する【Powered by NICT】
V. P. Anika, Winnie Luu, J. Laura, J. B. Andrew
20170 citations
Semantic Scholar
DHCR7:コレステロールとビタミンD生産の間の重要な酵素スイッチ【Powered by NICT】
V. P. Anika, Winnie Luu, Dian-Fan Li, J. Laura +1 more
20160 citations
Semantic Scholar
The Interplay between Cholesterol and Vitamin D Biosynthesis
A. V. Prabhu, Winnie Luu, Laura J. Sharpe, Andrew J. Brown
20150 citations
Semantic Scholar
Signalling and cholesterol metabolism
Winnie Luu, Laura J. Sharpe, J. Stevenson, Andrew J. Brown
20130 citations
Semantic Scholar

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Andrew J. Brown×18
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Laura J. Sharpe×17
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A. V. Prabhu×6
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