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N. Heller · SciRah

Researcher profile · Semantic Scholar

N. Heller

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N. Heller — researcher profile on SciRah

h-index: 26
Works: 94
Citations: 3,177

Most-cited papers

Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system.
S. L. LaPorte, Z. Sean Juo, J. Václavíková, Leremy A. Colf +4 more
2008Cell520 citations Open access
Semantic Scholar
Regulation of inflammation by interleukin‐4: a review of “alternatives”
I. Luzina, A. Keegan, N. Heller, G. Rook +2 more
2012Journal of Leukocyte Biology353 citations Open access
Semantic Scholar
COMMENTARY: IL-4 AND IL-13 RECEPTORS AND SIGNALING
S. McCormick, N. Heller
2015Cytokine305 citations Open access
Semantic Scholar
Estrogen Signaling Modulates Allergic Inflammation and Contributes to Sex Differences in Asthma
Aleksander Keselman, N. Heller
2015Frontiers in Immunology172 citations Open access
Semantic Scholar
Type I IL-4 Receptors Selectively Activate IRS-2 to Induce Target Gene Expression in Macrophages
N. Heller, Xiulan Qi, I. Junttila, K. Shirey +3 more
2008Science Signaling161 citations Open access
Semantic Scholar
Estrogen signaling contributes to sex differences in macrophage polarization during asthma
Aleksander Keselman, Xi Fang, Preston B. White, N. Heller
2017Journal of Immunology156 citations Open access
Semantic Scholar
Androgen and androgen receptor as enhancers of M2 macrophage polarization in allergic lung inflammation
Mireya Becerra-Díaz, Ashley B. Strickland, Aleksander Keselman, N. Heller
2018Journal of Immunology131 citations Open access
Semantic Scholar
Alternative Activation-Skewed Microglia/Macrophages Promote Hematoma Resolution in Experimental Intracerebral Hemorrhage
Che-Feng Chang, Jie-Ru Wan, Qiang Li, Stephen C. Renfroe +2 more
2017Neurobiology of Disease120 citations Open access
Semantic Scholar
Engineering the IL‐4/IL‐13 axis for targeted immune modulation
Zachary J. Bernstein, Anjali Shenoy, Amy Chen, N. Heller +1 more
2023Immunological Reviews116 citations Open access
Semantic Scholar
Translational Research in Acute Lung Injury and Pulmonary Fibrosis Enhanced resolution of experimental ARDS through IL-4-mediated lung macrophage reprogramming
F. D'Alessio, J. Craig, X. B. D. Singer, X. D. C. Files +12 more
201698 citations
Semantic Scholar
Female Sex and Gender in Lung/Sleep Health and Disease. Increased Understanding of Basic Biological, Pathophysiological, and Behavioral Mechanisms Leading to Better Health for Female Patients with Lung Disease
Mei-Lan K. Han, E. Arteaga-Solis, J. Blenis, G. Bourjeily +23 more
2018American Journal of Respiratory and Critical Care Medicine80 citations Open access
Semantic Scholar
Androgen and Androgen Receptors as Regulators of Monocyte and Macrophage Biology in the Healthy and Diseased Lung
Mireya Becerra-Díaz, Mason Song, N. Heller
2020Frontiers in Immunology73 citations Open access
Semantic Scholar
Interferon-γ Inhibits STAT6 Signal Transduction and Gene Expression in Human Airway Epithelial Cells
N. Heller, S. Matsukura, S. Georas, M. Boothby +3 more
200460 citations Open access
Semantic Scholar
Proteolytic enzymes and catabolism: enhanced release of granulocyte proteinases in uremic intoxication and during hemodialysis.
A. Heidland, W. Hörl, N. Heller, H. Heine +2 more
1983Kidney international. Supplement59 citations
Semantic Scholar
Suppressor of Cytokine Signaling (SOCS)1 Regulates Interleukin-4 (IL-4)-activated Insulin Receptor Substrate (IRS)-2 Tyrosine Phosphorylation in Monocytes and Macrophages via the Proteasome*
S. McCormick, N. Gowda, J. Fang, N. Heller
2016Journal of Biological Chemistry54 citations Open access
Semantic Scholar
Regulation of Macrophage, Dendritic Cell, and Microglial Phenotype and Function by the SOCS Proteins
S. McCormick, N. Heller
2015Frontiers in Immunology54 citations Open access
Semantic Scholar
Suppression of Human Natural Killer Cells by Different Classes of Opioids
D. Maher, D. Walia, N. Heller
2019Anesthesia and Analgesia51 citations Open access
Semantic Scholar
Hypoxia-inducible factor 1α is a critical downstream mediator for hypoxia-induced mitogenic factor (FIZZ1/RELMα)-induced pulmonary hypertension
R. Johns, E. Takimoto, Lucas W. Meuchel, Esra Elsaigh +4 more
2015Arteriosclerosis, Thrombosis and Vascular Biology51 citations Open access
Semantic Scholar
Expression of the costimulatory molecule B7-H2 (inducible costimulator ligand) by human airway epithelial cells.
S. Kurosawa, A. Myers, Lie-Ping Chen, Sheng-Dian Wang +5 more
2003American Journal of Respiratory Cell and Molecular Biology43 citations
Semantic Scholar
IL-4 and IL-13 Receptor Signaling From 4PS to Insulin Receptor Substrate 2: There and Back Again, a Historical View
A. Keegan, J. Zamorano, Aleksander Keselman, N. Heller
2018Frontiers in Immunology42 citations Open access
Semantic Scholar
Morphine decreases the function of primary human natural killer cells by both TLR4 and opioid receptor signaling.
D. Maher, D. Walia, N. Heller
2020Brain, behavior, and immunity38 citations
Semantic Scholar
IL-4 Engagement of the Type I IL-4 Receptor Complex Enhances Mouse Eosinophil Migration to Eotaxin-1 In Vitro
N. Heller, William M. Gwinn, R. Donnelly, S. Constant +1 more
2012PLoS ONE38 citations Open access
Semantic Scholar
The TORC1-activated Proteins, p70S6K and GRB10, Regulate IL-4 Signaling and M2 Macrophage Polarization by Modulating Phosphorylation of Insulin Receptor Substrate-2*
N. Heller, Xi Fang, S. McCormick, N. Gowda +3 more
2015Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Sex differences in M2 polarization, chemokine and IL-4 receptors in monocytes and macrophages from asthmatics
Mireya Becerra-Díaz, Andrew D. Lerner, Diana H. Yu, J. Thiboutot +4 more
2020Cellular Immunology33 citations Open access
Semantic Scholar
An atopy-associated polymorphism in the ectodomain of the IL-4Rα chain (V50) regulates the persistence of STAT6 phosphorylation
Andrew Q. Ford, N. Heller, Linda M. Stephenson, M. Boothby +1 more
2009Journal of Immunology29 citations Open access
Semantic Scholar
Androgen-induced insulin resistance is ameliorated by deletion of hepatic androgen receptor in females
S. Andrisse, Mingxiao Feng, Zhiqiang Wang, O. Awe +14 more
2021The FASEB Journal28 citations Open access
Semantic Scholar
Interferon-gamma inhibits STAT6 signal transduction and gene expression in human airway epithelial cells.
N. Heller, S. Matsukura, S. Georas, M. Boothby +3 more
2004American Journal of Respiratory Cell and Molecular Biology25 citations
Semantic Scholar
COVID-19 and myeloid cells: complex interplay correlates with lung severity.
D, F. Alessio, N. Heller
2020Journal of Clinical Investigation23 citations Open access
Semantic Scholar
New perspectives on the regulation of type II inflammation in asthma
Mireya Becerra-Díaz, M. Wills-Karp, N. Heller
2017F1000Research23 citations Open access
Semantic Scholar
Faculty of 1000 evaluation for Emerging concepts of T cell metabolism as a target of immunotherapy.
N. Heller
201723 citations Open access
Semantic Scholar
The Extracellular and Transmembrane Domains of the γC and Interleukin (IL)-13 Receptor α1 Chains, Not Their Cytoplasmic Domains, Dictate the Nature of Signaling Responses to IL-4 and IL-13
N. Heller, Xiulan Qi, F. Gesbert, A. Keegan
2012Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Design of cell-type-specific hyperstable IL-4 mimetics via modular de novo scaffolds
Huilin Yang, Umut Y. Ulge, Alfredo Quijano-Rubio, Zachary J. Bernstein +21 more
2023Nature Chemical Biology19 citations Open access
Semantic Scholar
Steady-state estradiol triggers a unique innate immune response to allergen resulting in increased airway resistance
K. Warren, C. Deering-Rice, T. Huecksteadt, S. Trivedi +9 more
2023Biology of Sex Differences18 citations Open access
Semantic Scholar
Assessment of signal transducer and activator of transcription 6 as a target of glucocorticoid action in human airway epithelial cells
N. Heller, S. Matsukura, S. Georas, M. Boothby +2 more
2004Clinical and Experimental Allergy17 citations
Semantic Scholar
OXALOACETATE DECARBOXYLATION AND OXALOACETATE-CARBON DIOXIDE EXCHANGE IN ACETOBACTER XYLINUM
M. Benziman, N. Heller
1964Journal of Bacteriology17 citations Open access
Semantic Scholar
β-Catenin is required for the differentiation of iNKT2 and iNKT17 cells that augment IL-25-dependent lung inflammation
Rosa Berga-Bolaños, Archna Sharma, Farrah C. Steinke, K. Pyaram +7 more
2015BMC Immunology15 citations Open access
Semantic Scholar
Detection and quantitation of fatty acid acyl conjugates of triamcinolone acetonide via gas chromatography-electron-capture negative-ion mass spectrometry.
W. Hubbard, A. Blum, C. Bickel, N. Heller +1 more
2003Analytical Biochemistry14 citations
Semantic Scholar
Faculty Opinions recommendation of Differential regulation of IL-4Ralpha expression by antigen versus cytokine stimulation characterizes Th2 progression in vivo.
A. Keegan, N. Heller
201013 citations
Semantic Scholar
The Type I and Type II Receptor Complexes for IL-4 and IL-13 Differentially Regulate Allergic Lung Inflammation
N. Heller, Preeta Dasgupta, Nicolas Dorsey, S. Chapoval +1 more
20129 citations Open access
Semantic Scholar
Natural Killer T (NKT) Cells in Mice and Men
N. Heller, Rosa Berga-Bolaños, Lynette B. Naler, J. Sen
20178 citations
Semantic Scholar
Faculty Opinions recommendation of Nod2-dependent Th2 polarization of antigen-specific immunity.
A. Keegan, N. Heller
20086 citations
Semantic Scholar
Airway epithelial cell activation and toll-like receptors (TLR)
Quan Sha, J. Plitt, N. Heller, L. Beck +2 more
20035 citations Open access
Semantic Scholar
Reduced allergic lung inflammation and airway responsiveness in mice lacking the cytoskeletal protein gelsolin.
M. Mikami, G. Yocum, N. Heller, C. Emala
2020American Journal of Physiology - Lung cellular and Molecular Physiology4 citations Open access
Semantic Scholar
Role of the RNA-binding Protein Tristetraprolin (TTP) in Glucocorticoid (GC)-mediated Gene Regulation
F. Ishmael, Xi Fang, N. Heller, Jin-Shui Fan +4 more
20074 citations
Semantic Scholar
Post-transcriptional regulation of eotaxin by glucocorticoids (GC) and by interleukin (IL)-4
N. Heller, S. Curry, R. Nickel, B. Plunkett +4 more
20024 citations Open access
Semantic Scholar
Faculty Opinions recommendation of Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung.
N. Heller
20172 citations
Semantic Scholar
IL-4/IL-13 signaling responses are dictated by the extracellular/transmembrane domain of the receptor complex, not the cytoplasmic domain (174.3)
N. Heller, Xiulan Qi, F. Gesbert, A. Keegan
2012Journal of Immunology2 citations
Semantic Scholar
The role of macrophages in the mitigation by decitabine of acute allograft rejection
W. Daccarett-Bojanini, Manuel Sollmann, Kristine Yarnoff, N. Heller +1 more
2025Frontiers in Transplantation1 citations Open access
Semantic Scholar
Hepatocyte androgen receptor in females mediates androgen-induced hepatocellular glucose mishandling and systemic insulin resistance
S. Andrisse, Mingxiao Feng, Zhiqiang Wang, O. Awe +14 more
2021bioRxiv1 citations Open access
Semantic Scholar
Unexpected role for androgen and androgen receptor as enhancers of M2 macrophage polarization
Mireya Becerra-Díaz, Ashley B. Strickland, Aleksander Keselman, N. Heller
2018Journal of Immunology1 citations
Semantic Scholar

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S. Matsukura×3

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Ashley B. Strickland — researcher profile on SciRah