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S. Constant · SciRah

Researcher profile · Semantic Scholar

S. Constant

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S. Constant — researcher profile on SciRah

h-index: 35
Works: 70
Citations: 7,695

Most-cited papers

Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches.
S. Constant, K. Bottomly
1997Annual Review of Immunology1,691 citations
Semantic Scholar
Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells
S. Constant, Christiane Pfeiffer, Ann Woodard, T. Pasqualini +1 more
1995Journal of Experimental Medicine787 citations Open access
Semantic Scholar
Mechanism of Transforming Growth Factor β–induced Inhibition of T Helper Type 1 Differentiation
L. Gorelik, S. Constant, R. Flavell
2002Journal of Experimental Medicine553 citations Open access
Semantic Scholar
B lymphocytes can be competent antigen-presenting cells for priming CD4+ T cells to protein antigens in vivo.
S. Constant, N. Schweitzer, J. West, Patricia Ranney +1 more
1995Journal of Immunology347 citations
Semantic Scholar
Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiation.
X. Tao, S. Constant, P. Jorritsma, K. Bottomly
1997Journal of Immunology312 citations
Semantic Scholar
Del-1 is an endogenous inhibitor of leukocyte-endothelial adhesion limiting inflammatory cell recruitment
E. Choi, E. Chavakis, M. Czabanka, H. Langer +17 more
2008Science284 citations Open access
Semantic Scholar
Cyclophilin–CD147 interactions: a new target for anti-inflammatory therapeutics
V. Yurchenko, S. Constant, E. Eisenmesser, M. Bukrinsky
2010Clinical and Experimental Immunology265 citations Open access
Semantic Scholar
MyD88-dependent induction of allergic Th2 responses to intranasal antigen.
D. Piggott, S. Eisenbarth, Lan Xu, S. Constant +3 more
2005Journal of Clinical Investigation253 citations Open access
Semantic Scholar
B lymphocytes as antigen-presenting cells for CD4+ T cell priming in vivo.
S. Constant
1999Journal of Immunology244 citations Open access
Semantic Scholar
Extracellular Cyclophilins Contribute to the Regulation of Inflammatory Responses1
Kamalpreet Arora, William M. Gwinn, M. A. Bower, Alan R. Watson +4 more
2005Journal of Immunology234 citations Open access
Semantic Scholar
Resident lung antigen-presenting cells have the capacity to promote Th2 T cell differentiation in situ.
S. Constant, J. Brogdon, D. Piggott, C. Herrick +3 more
2002Journal of Clinical Investigation221 citations Open access
Semantic Scholar
Pivotal Advance: Eosinophil infiltration of solid tumors is an early and persistent inflammatory host response
S. Cormier, A. Taranova, C. Bedient, Thanh Nguyen +11 more
2006Journal of Leukocyte Biology191 citations Open access
Semantic Scholar
Internalization of Leishmania mexicana Complex Amastigotes via the Fc Receptor Is Required to Sustain Infection in Murine Cutaneous Leishmaniasis
Peter E. Kima, S. Constant, Lynn G. Hannum, M. Colmenares +4 more
2000Journal of Experimental Medicine189 citations Open access
Semantic Scholar
Induction of IL-4-producing CD4+ T cells by antigenic peptides altered for TCR binding.
X. Tao, C. Grant, S. Constant, K. Bottomly
1997Journal of Immunology189 citations Open access
Semantic Scholar
Dealing with the family: CD147 interactions with cyclophilins
V. Yurchenko, S. Constant, M. Bukrinsky
2005Immunology182 citations Open access
Semantic Scholar
Mechanism of Transforming Growth Factor (cid:2) –induced Inhibition of T Helper Type 1 Differentiation
L. Gorelik, S. Constant, R. Flavell
2002124 citations
Semantic Scholar
Preferential chemotaxis of activated human CD4+ T cells by extracellular cyclophilin A
Jesse M. Damsker, M. Bukrinsky, S. Constant
2007Journal of Leukocyte Biology117 citations Open access
Semantic Scholar
CD4 regulation of TCR signaling and T cell differentiation following stimulation with peptides of different affinities for the TCR.
D. Leitenberg, Yvan Boutin, S. Constant, K. Bottomly
1998Journal of Immunology101 citations
Semantic Scholar
Immunobiology of hookworm infection.
A. Loukas, S. Constant, J. Bethony
2005FEMS Immunology & Medical Microbiology99 citations Open access
Semantic Scholar
Lung Inflammation, Injury, and Proliferative Response after Repetitive Particulate Hexavalent Chromium Exposure
L. Beaver, Erik J. Stemmy, A. Schwartz, Jesse M. Damsker +3 more
2009Environmental Health Perspectives96 citations Open access
Semantic Scholar
Targeting the chemotactic function of CD147 reduces collagen‐induced arthritis
Jesse M. Damsker, Ifeanyi Okwumabua, T. Pushkarsky, Kamalpreet Arora +2 more
2009Immunology91 citations Open access
Semantic Scholar
JNK1 Is Required for T Cell-Mediated Immunity Against Leishmania major Infection1
S. Constant, C. Dong, Derek D. Yang, M. Wysk +2 more
2000Journal of Immunology84 citations Open access
Semantic Scholar
LUNG INJURY, INFLAMMATION AND AKT SIGNALING FOLLOWING INHALATION OF PARTICULATE HEXAVALENT CHROMIUM
L. Beaver, Erik J. Stemmy, S. Constant, A. Schwartz +6 more
2008Toxicology and Applied Pharmacology78 citations Open access
Semantic Scholar
Novel Approach to Inhibit Asthma-Mediated Lung Inflammation Using Anti-CD147 Intervention1
William M. Gwinn, Jesse M. Damsker, R. Falahati, Ifeanyi Okwumabua +8 more
2006Journal of Immunology76 citations Open access
Semantic Scholar
Necator americanus: the Na-ASP-2 protein secreted by the infective larvae induces neutrophil recruitment in vivo and in vitro.
M. A. Bower, S. Constant, S. Mendez
2008Experimental parasitology74 citations Open access
Semantic Scholar
A Secreted Protein from the Human Hookworm Necator americanus Binds Selectively to NK Cells and Induces IFN-γ Production
G. C. Hsieh, A. Loukas, A. Wahl, M. Bhatia +8 more
2004Journal of Immunology73 citations
Semantic Scholar
Cutting Edge: Genetic Variation Influences FcεRI-Induced Mast Cell Activation and Allergic Responses1
Y. Yamashita, N. Charles, Y. Furumoto, S. Odom +6 more
2007Journal of Immunology70 citations Open access
Semantic Scholar
Isoform-specific Inhibition of Cyclophilins
Sebastian Daum, M. Schumann, S. Mathea, T. Aumüller +6 more
2009Biochemistry69 citations Open access
Semantic Scholar
A Cell-Impermeable Cyclosporine A Derivative Reduces Pathology in a Mouse Model of Allergic Lung Inflammation
M. Balsley, M. Malešević, Erik J. Stemmy, Jason P. Gigley +5 more
2010Journal of Immunology52 citations Open access
Semantic Scholar
Liver proteomics for therapeutic drug discovery: Inhibition of the cyclophilin receptor CD147 attenuates sepsis-induced acute renal failure*
J. Dear, Asada Leelahavanichkul, A. Aponte, Xu-Zhen Hu +4 more
2007Critical Care Medicine44 citations Open access
Semantic Scholar
A Cyclosporin Derivative Discriminates between Extracellular and Intracellular Cyclophilins
M. Malešević, Jan Kühling, F. Erdmann, M. Balsley +3 more
2010Angewandte Chemie43 citations Open access
Semantic Scholar
Leishmania pifanoi Pathogenesis: Selective Lack of a Local Cutaneous Response in the Absence of Circulating Antibody
M. Colmenares, S. Constant, Peter E. Kima, D. McMahon-Pratt
2002Infection and Immunity42 citations Open access
Semantic Scholar
Exposure to Particulate Hexavalent Chromium Exacerbates Allergic Asthma Pathology
Brent Schneider, S. Constant, S. Patierno, R. Jurjus +1 more
2011Toxicology and Applied Pharmacology41 citations Open access
Semantic Scholar
Cutting edge: genetic variation influences Fc epsilonRI-induced mast cell activation and allergic responses.
Y. Yamashita, N. Charles, Y. Furumoto, S. Odom +6 more
2007Journal of Immunology39 citations
Semantic Scholar
IL-4 Engagement of the Type I IL-4 Receptor Complex Enhances Mouse Eosinophil Migration to Eotaxin-1 In Vitro
N. Heller, William M. Gwinn, R. Donnelly, S. Constant +1 more
2012PLoS ONE38 citations Open access
Semantic Scholar
Deficient inflammatory response to UV radiation in neonatal mice
A. Wolnicka-Głubisz, Jesse M. Damsker, S. Constant, Stephanie Corn +2 more
2007Journal of Leukocyte Biology32 citations Open access
Semantic Scholar
Are primed CD4+ T lymphocytes different from unprimed cells?
S. Constant, M. Zain, J. West, T. Pasqualini +2 more
1994European Journal of Immunology31 citations
Semantic Scholar
In vivo lymphocyte responses in the draining lymph nodes of mice exposed to Schistosoma mansoni: preferential proliferation of T cells is central to the induction of protective immunity.
S. Constant, R. Wilson
1992Cellular Immunology30 citations
Semantic Scholar
Cyclophilin A cooperates with MIP-2 to augment neutrophil migration
S. Heine, Denise S. Olive, Ji-Liang Gao, P. Murphy +2 more
2011Journal of Inflammation Research28 citations Open access
Semantic Scholar
VBP15, a Glucocorticoid Analogue, Is Effective at Reducing Allergic Lung Inflammation in Mice
Jesse M. Damsker, Blythe C. Dillingham, M. Rose, M. Balsley +16 more
2013PLoS ONE27 citations Open access
Semantic Scholar
Extracellular Cyclophilin Levels Associate with Parameters of Asthma in Phenotypic Clusters
Erik J. Stemmy, A. Benton, J. Lerner, S. Alcala +2 more
2011Journal of Asthma27 citations Open access
Semantic Scholar
Phenotypic analysis of the cellular responses in regional lymphoid organs of mice vaccinated against Schistosoma mansoni
S. Constant, A. Mountford, R. Wilson
1990Parasitology25 citations
Semantic Scholar
Blocking cyclophilins in the chronic phase of asthma reduces the persistence of leukocytes and disease reactivation.
Erik J. Stemmy, M. Balsley, R. Jurjus, Jesse M. Damsker +2 more
2011American Journal of Respiratory Cell and Molecular Biology23 citations Open access
Semantic Scholar
The level of CD147 expression correlates with cyclophilin-induced signalling and chemotaxis
A. Trachtenberg, T. Pushkarsky, S. Heine, S. Constant +2 more
2011BMC Research Notes21 citations Open access
Semantic Scholar
Binding of Excreted and/or Secreted Products of Adult Hookworms to Human NK Cells in Necator americanus-Infected Individuals from Brazil
A. Teixeira-Carvalho, R. Fujiwara, Erik J. Stemmy, Denise S. Olive +5 more
2008Infection and Immunity21 citations Open access
Semantic Scholar
CD4 and CD45 regulate qualitatively distinct patterns of calcium mobilization in individual CD4+ T cells
D. Leitenberg, S. Constant, D. Lu, Brian R. Smith +1 more
1995European Journal of Immunology21 citations
Semantic Scholar
A Nonproliferating Parvovirus Vaccine Vector Elicits Sustained, Protective Humoral Immunity following a Single Intravenous or Intranasal Inoculation
G. Palmer, J. Brogdon, S. Constant, P. Tattersall
2004Journal of Virology11 citations Open access
Semantic Scholar
Abstract 5456: Potential role of nitric oxide in chromium-induced lung carcinogenesis
T. Forbes, Lauren Hopkins, Brent Schneider, L. Lazarus +5 more
20124 citations
Semantic Scholar
CYCLOPHILIN A IS A MEDIATOR OF PARACETAMOL-INDUCED LIVER INJURY
M. Nicolai, J. H. Catterson, T. Huizinga, K. Dhaliwal +6 more
20092 citations
Semantic Scholar
Abstract 5734: Role of the inflammasome complex in Cr(VI)-induced lung injury and inflammation
Lauren Hopkins, T. Forbes, Brent Schneider, S. Constant +4 more
20121 citations
Semantic Scholar

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M. Bukrinsky×9
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Erik J. Stemmy×7
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Jesse M. Damsker×7
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D. Leitenberg — researcher profile on SciRah

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M. Balsley — researcher profile on SciRah

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M. A. Bower — researcher profile on SciRah

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A. Schwartz — researcher profile on SciRah

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R. Flavell — researcher profile on SciRah

William M. Gwinn×3

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William M. Gwinn — researcher profile on SciRah