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T. Monie · SciRah

Researcher profile · Semantic Scholar

T. Monie

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T. Monie — researcher profile on SciRah

h-index: 31
Works: 82
Citations: 3,581

Most-cited papers

Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex
Si-Ming Man, Lee J. Hopkins, E. Nugent, S. Cox +6 more
2014Proceedings of the National Academy of Sciences of the United States of America332 citations Open access
Semantic Scholar
Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate interleukin-1β production
Si-Ming Man, Panagiotis Tourlomousis, Lee J. Hopkins, T. Monie +2 more
2013Journal of Immunology235 citations Open access
Semantic Scholar
THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Catalytic receptors
Stephen P. H. Alexander, D. Fabbro, E. Kelly, A. Mathie +16 more
2019British Journal of Pharmacology209 citations Open access
Semantic Scholar
A Dimer of the Toll-Like Receptor 4 Cytoplasmic Domain Provides a Specific Scaffold for the Recruitment of Signalling Adaptor Proteins
Ricardo Núñez Miguel, J. Wong, Julian F. Westoll, Heather J. Brooks +4 more
2007PLoS ONE203 citations Open access
Semantic Scholar
The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors
Stephen P. H. Alexander, Doriano Fabbro, E. Kelly, A. Mathie +24 more
2023British Journal of Pharmacology171 citations Open access
Semantic Scholar
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors
Stephen P. H. Alexander, D. Fabbro, E. Kelly, A. Mathie +25 more
2021British Journal of Pharmacology164 citations Open access
Semantic Scholar
Viral Inhibitory Peptide of TLR4, a Peptide Derived from Vaccinia Protein A46, Specifically Inhibits TLR4 by Directly Targeting MyD88 Adaptor-Like and TRIF-Related Adaptor Molecule
Tatyana Lysakova-Devine, B. Keogh, B. Harrington, Kamalpreet Nagpal +4 more
2010Journal of Immunology147 citations Open access
Semantic Scholar
Pathogen Sensing by Nucleotide-binding Oligomerization Domain-containing Protein 2 (NOD2) Is Mediated by Direct Binding to Muramyl Dipeptide and ATP
J. Mo, Joseph P. Boyle, Christopher B. Howard, T. Monie +2 more
2012Journal of Biological Chemistry145 citations Open access
Semantic Scholar
Elucidation of the MD-2/TLR4 interface required for signalling by Lipid IVa
Catherine Walsh, M. Gangloff, T. Monie, T. Smyth +5 more
2008Journal of Immunology124 citations Open access
Semantic Scholar
Structure and RNA interactions of the N-terminal RRM domains of PTB.
P. Simpson, T. Monie, A. Szendrői, N. Davydova +8 more
2004Structure108 citations Open access
Semantic Scholar
Structural insights into the transcriptional and translational roles of Ebp1
T. Monie, A. Perrin, J. Birtley, T. Sweeney +6 more
2007EMBO Journal107 citations Open access
Semantic Scholar
A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain
Alexis P. Rideau, C. Gooding, P. Simpson, T. Monie +6 more
2006Nature Structural &Molecular Biology104 citations
Semantic Scholar
Insights into the molecular basis of the NOD2 signalling pathway
Joseph P. Boyle, R. Parkhouse, T. Monie
2014Open Biology102 citations Open access
Semantic Scholar
Allergens as Immuno-Modulatory Proteins: the cat dander protein Fel d 1 enhances Toll-like receptor activation by lipid ligands
J. Herre, H. Grönlund, Heather J. Brooks, Lee J. Hopkins +9 more
2013Journal of Immunology101 citations Open access
Semantic Scholar
Mice, men and the relatives: cross-species studies underpin innate immunity
C. Bryant, T. Monie
2012Open Biology90 citations Open access
Semantic Scholar
Innate immune system
T. Monie
2010The Biomedical & Life Sciences Collection88 citations
Semantic Scholar
The Concise Guide to PHARMACOLOGY 2025/26: Catalytic receptors
Stephen P. H. Alexander, Doriano Fabbro, Chloe J. Peach, Alasdair J. Gibb +28 more
2025British Journal of Pharmacology86 citations Open access
Semantic Scholar
Activating immunity: lessons from the TLRs and NLRs.
T. Monie, C. Bryant, N. Gay
2009TIBS -Trends in Biochemical Sciences. Regular ed81 citations
Semantic Scholar
Caspase‐8 functions as a key mediator of inflammation and pro‐IL‐1β processing via both canonical and non‐canonical pathways
T. Monie, C. Bryant
2015Immunological Reviews74 citations Open access
Semantic Scholar
International Union of Basic and Clinical Pharmacology. XCVI. Pattern Recognition Receptors in Health and Disease
C. Bryant, Selinda J. Orr, B. Ferguson, M. Symmons +2 more
2015Pharmacological Reviews68 citations Open access
Semantic Scholar
Conformation of polypyrimidine tract binding protein in solution.
M. Petoukhov, T. Monie, F. Allain, S. Matthews +2 more
2006Structure67 citations Open access
Semantic Scholar
The polypyrimidine tract binding protein is a monomer.
T. Monie, Helena Hernández, C. Robinson, P. Simpson +2 more
2005RNA: A publication of the RNA Society59 citations Open access
Semantic Scholar
Identification of LukPQ, a novel, equid-adapted leukocidin of Staphylococcus aureus
G. Koop, M. Vrieling, Daniel M. L. Storisteanu, Laurence S. C. Lok +30 more
2017Scientific Reports58 citations Open access
Semantic Scholar
TRIL, a Functional Component of the TLR4 Signaling Complex, Highly Expressed in Brain1
S. Carpenter, Thaddeus J. Carlson, J. Dellacasagrande, Amaya Garcia +11 more
2009Journal of Immunology57 citations Open access
Semantic Scholar
Comparative Genomic and Sequence Analysis Provides Insight into the Molecular Functionality of NOD1 and NOD2
Joseph P. Boyle, Sophie Mayle, R. Parkhouse, T. Monie
2013Frontiers in Immunology52 citations Open access
Semantic Scholar
Blau syndrome polymorphisms in NOD2 identify nucleotide hydrolysis and helical domain 1 as signalling regulators
R. Parkhouse, Joseph P. Boyle, T. Monie
2014FEBS Letters40 citations Open access
Semantic Scholar
NLR activation takes a direct route.
T. Monie
2013TIBS -Trends in Biochemical Sciences. Regular ed40 citations
Semantic Scholar
Structure and regulation of cytoplasmic adapter proteins involved in innate immune signaling
T. Monie, Martin C. Moncrieffe, Nicholas J. Gay
2009Immunological Reviews36 citations
Semantic Scholar
The immunoglobulin domain of the sodium channel β3 subunit contains a surface-localized disulfide bond that is required for homophilic binding
Nikitha R Yereddi, F. Cusdin, Sivakumar Namadurai, L. Packman +5 more
2013The FASEB Journal34 citations Open access
Semantic Scholar
CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages
Milton C. A. Pereira, Panagiotis Tourlomousis, John A. Wright, T. Monie +1 more
2016Nature Communications33 citations Open access
Semantic Scholar
Intestinal APCs of the endogenous nanomineral pathway fail to express PD-L1 in Crohn’s disease
Jack Robertson, Carolin T. Haas, L. Pele, T. Monie +4 more
2016Scientific Reports33 citations Open access
Semantic Scholar
Evolutionary loss of inflammasomes in the Carnivora and implications for the carriage of zoonotic infections
Zsofia Digby, Panagiotis Tourlomousis, J. Rooney, Joseph P. Boyle +10 more
2021Cell Reports28 citations Open access
Semantic Scholar
Engagement of Nucleotide-binding Oligomerization Domain-containing Protein 1 (NOD1) by Receptor-interacting Protein 2 (RIP2) Is Insufficient for Signal Transduction
Sophie Mayle, Joseph P. Boyle, Eiki Sekine, B. Zurek +2 more
2014Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Connecting the Innate and Adaptive Immune Responses
T. Monie
201725 citations
Semantic Scholar
Ultrasmall silica nanoparticles directly ligate the T cell receptor complex
B. Vis, Rachel E Hewitt, T. Monie, Camilla J. Fairbairn +3 more
2019Proceedings of the National Academy of Sciences of the United States of America24 citations Open access
Semantic Scholar
Dynamic phosphorylation of RelA on Ser42 and Ser45 in response to TNFα stimulation regulates DNA binding and transcription
Francesco Lanucara, Connie W. Lam, J. Mann, T. Monie +7 more
2016Open Biology23 citations Open access
Semantic Scholar
Interaction between NOD2 and CARD9 involves the NOD2 NACHT and the linker region between the NOD2 CARDs and NACHT domain
R. Parkhouse, Joseph P. Boyle, Sophie Mayle, K. Sawmynaden +2 more
2014FEBS Letters22 citations Open access
Semantic Scholar
The N-Terminal Region of the Human Autophagy Protein ATG16L1 Contains a Domain That Folds into a Helical Structure Consistent with Formation of a Coiled-Coil
R. Parkhouse, Ima-obong Ebong, C. Robinson, T. Monie
2013PLoS ONE19 citations Open access
Semantic Scholar
Innate Immune Sensors and Gastrointestinal Bacterial Infections
G. Hold, I. Mukhopadhya, T. Monie
2011Clinical and Developmental Immunology18 citations Open access
Semantic Scholar
The Canonical Inflammasome: A Macromolecular Complex Driving Inflammation.
T. Monie
2017Sub-cellular biochemistry17 citations
Semantic Scholar
A Novel Mutation in Helical Domain 2 of NOD2 in Sporadic Blau Syndrome
L. Jain, N. Gupta, M. Reddy, R. Mittal +4 more
2016Ocular immunology and inflammation13 citations Open access
Semantic Scholar
Dysfunctional Crohn’s Disease-Associated NOD2 Polymorphisms Cannot be Reliably Predicted on the Basis of RIPK2 Binding or Membrane Association
R. Parkhouse, T. Monie
2015Frontiers in Immunology13 citations Open access
Semantic Scholar
Insights into the molecular basis of the NOD 2 signalling pathway
Joseph P. Boyle, R. Parkhouse, T. Monie
201413 citations
Semantic Scholar
Oligonucleotide mapping of the core genomic RNA dimer linkage in human T-cell leukaemia virus type-1.
T. Monie, J. Greatorex, A. M. Lever
2001Virus Research13 citations
Semantic Scholar
Polymorphisms at Amino Acid Residues 141 and 154 Influence Conformational Variation in Ovine PrP
Sujeong Yang, A. M. Thackray, Lee J. Hopkins, T. Monie +2 more
2014BioMed Research International11 citations Open access
Semantic Scholar
Cell Swelling and the NLRP3 Inflammasome
Joseph P. Boyle, C. Bryant, T. Monie
2013Immunity11 citations Open access
Semantic Scholar
Computational analysis predicts the Kaposi's sarcoma-associated herpesvirus tegument protein ORF63 to be alpha helical
Joseph P. Boyle, T. Monie
2012Proteins: Structure, Function, and Bioinformatics8 citations Open access
Semantic Scholar
Identification and visualization of the Dimerization initiation site of the prototype lentivirus, Maedi Visna Virus: A potential GACG tetraloop displays structural homology with the α- and γ-retroviruses
T. Monie, J. Greatorex, Laura Maynard-Smith, Ben D. C. Hook +3 more
20058 citations
Semantic Scholar
A Snapshot of the Innate Immune System
T. Monie
20177 citations
Semantic Scholar
The human T-cell lymphotropic virus type-I dimerization initiation site forms a hairpin loop, unlike previously characterized retroviral dimerization motifs.
T. Monie, J. Greatorex, M. Zacharias, A. Lever
2004Biochemistry6 citations
Semantic Scholar

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