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Samantha Bucktrout · SciRah

Researcher profile · Semantic Scholar

Samantha Bucktrout

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Samantha Bucktrout — researcher profile on SciRah

h-index: 12
Works: 30
Citations: 2,330

Most-cited papers

Clonal replacement of tumor-specific T cells following PD-1 blockade
Kathryn E. Yost, Ansuman T. Satpathy, Daniel K. Wells, Yan-Yan Qi +12 more
2019Nature Medicine1,393 citations Open access
Semantic Scholar
Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial
Lacey J. Padrón, Deena M. Maurer, M. O'Hara, E. O'Reilly +33 more
2022Nature Medicine325 citations Open access
Semantic Scholar
CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study.
M. O'Hara, E. O'Reilly, G. Varadhachary, R. Wolff +28 more
2021The Lancet Oncology240 citations
Semantic Scholar
GITR ligation enhances functionality of tumor‐infiltrating T cells in hepatocellular carcinoma
A. V. van Beek, Guoying Zhou, M. Doukas, P. Boor +13 more
2019International Journal of Cancer56 citations Open access
Semantic Scholar
Characterization and comparison of GITR expression in solid tumors
L. Vence, Samantha Bucktrout, Irina Fernandez Curbelo, J. Blando +16 more
2019Clinical Cancer Research47 citations Open access
Semantic Scholar
Ipilimumab alone or in combination with nivolumab in patients with advanced melanoma who have progressed or relapsed on PD-1 blockade: clinical outcomes and translational biomarker analyses
C. Friedman, C. Spencer, Christopher R. Cabanski, K. Panageas +16 more
2022Journal for ImmunoTherapy of Cancer45 citations Open access
Semantic Scholar
Recent advances in immunotherapies: from infection and autoimmunity, to cancer, and back again
Samantha Bucktrout, J. Bluestone, F. Ramsdell
2018Genome Medicine37 citations Open access
Semantic Scholar
Immunomodulatory activity of humanized anti-IL-7R monoclonal antibody RN168 in subjects with type 1 diabetes.
K. Herold, Samantha Bucktrout, Xiao Wang, B. Bode +14 more
2019JCI Insight36 citations Open access
Semantic Scholar
Multi-omic landscape of human gliomas from diagnosis to treatment and recurrence
Hadeesha Piyadasa, Benjamin Oberlton, Mikaela K. Ribi, K. Leow +36 more
2025Cancer Cell27 citations Open access
Semantic Scholar
Development of preclinical and clinical models for immune-related adverse events following checkpoint immunotherapy: a perspective from SITC and AACR
N. Bayless, J. Bluestone, Samantha Bucktrout, L. Butterfield +7 more
2021Journal for ImmunoTherapy of Cancer27 citations Open access
Semantic Scholar
Associations between immune checkpoint inhibitor response, immune-related adverse events, and steroid use in RADIOHEAD: a prospective pan-tumor cohort study
Z. Quandt, Anastasia Lucas, Samantha I. Liang, En-Jun Yang +15 more
2025Journal for ImmunoTherapy of Cancer24 citations Open access
Semantic Scholar
Gemcitabine (Gem) and nab-paclitaxel (NP) ± nivolumab (nivo) ± CD40 agonistic monoclonal antibody APX005M (sotigalimab), in patients (Pts) with untreated metastatic pancreatic adenocarcinoma (mPDAC): Phase (Ph) 2 final results.
M. O'Hara, E. O'Reilly, R. Wolff, Z. Wainberg +16 more
202122 citations
Semantic Scholar
The future of cancer immunotherapy for brain tumors: a collaborative workshop
Christine E. Brown, Samantha Bucktrout, L. Butterfield, O. Futer +7 more
2022Journal of Translational Medicine12 citations Open access
Semantic Scholar
Model-Based Characterization of the Pharmacokinetics, Target Engagement Biomarkers, and Immunomodulatory Activity of PF-06342674, a Humanized mAb Against IL-7 Receptor-α, in Adults with Type 1 Diabetes
Jason H. Williams, C. Udata, B. Ganguly, Samantha Bucktrout +6 more
2020AAPS Journal12 citations Open access
Semantic Scholar
Immunologic signatures of response and resistance to nivolumab with ipilimumab in advanced metastatic cancer
A. Tsimberidou, Farah A. Alayli, Kwame Okrah, A. Drakaki +36 more
2024Journal of Experimental Medicine11 citations Open access
Semantic Scholar
Multi-omic landscape of human gliomas from diagnosis to treatment and recurrence
Hadeesha Piyadasa, Benjamin Oberlton, Mikaela K. Ribi, Jolene S. Ranek +35 more
2025bioRxiv7 citations Open access
Semantic Scholar
Phase 1 clinical trial results for NG-350A, a novel transgene-armed and tumor-selective vector: Differential effects of intravenous (IV) versus intratumoral (IT) dosing on immune pharmacodynamics (PD).
Minesh Patel, Chris Cox, D. Krige, Lyle Walker +8 more
2023Journal of Clinical Oncology4 citations
Semantic Scholar
Advancing T cell–based cancer therapy with single-cell technologies
Samantha Bucktrout, N. Banovich, L. Butterfield, Cansu Cimen-Bozkus +11 more
2022Nature Medicine4 citations
Semantic Scholar
1003 Tumor-specific replication and immunoactivity of aCD40-producing T-SIGn vectors
Maria Stella Sasso, Meg Snowden, R. Lear, Linnea Drexhage +7 more
2024Regular and Young Investigator Award Abstracts1 citations Open access
Semantic Scholar
Abstract 2740: Safe and effective delivery of antibody fragments to the solid tumor microenvironment
R. Bergin, Amandine Pelletier, M. Zonca, A. Muntzer +9 more
2023Cancer Research1 citations
Semantic Scholar
765 NG-350A, a tumor-selective anti-CD40 agonist expressing therapeutic, gemcitabine/nab-paclitaxel and ipilimumab for untreated metastatic pancreatic adenocarcinoma: cohort C of the REVOLUTION trial
E. O'Reilly, M. O'Hara, George A. Fisher, Robert A. Wolff +15 more
2023Regular and Young Investigator Award Abstracts1 citations Open access
Semantic Scholar
656 Exploratory platform trial to evaluate immunotherapy combinations with chemotherapy for the treatment of patients with previously untreated metastatic pancreatic adenocarcinoma (REVOLUTION)
Jaclyn P Lyman, E. O'Reilly, Z. Wainberg, G. Fisher +28 more
2022Regular and Young Investigator Award Abstracts1 citations Open access
Semantic Scholar
The future of cancer immunotherapy for brain tumors: a collaborative workshop
C. Brown, Samantha Bucktrout, L. Butterfield, O. Futer +7 more
2022Journal of Translational Medicine1 citations Open access
Semantic Scholar
587 AMADEUS trial: tumor agnostic pre- and on-treatment biomarkers of response to nivolumab plus ipilimumab correlate with on-treatment tumoral T cell infiltration
Farah Alayli, Kwame Okrah, A. Tsimberidou, A. Drakaki +30 more
2022Regular and Young Investigator Award Abstracts1 citations Open access
Semantic Scholar
Publisher Correction: Advancing T cell–based cancer therapy with single-cell technologies
Samantha Bucktrout, N. Banovich, Lisa H. Butterfield, Cansu Cimen-Bozkus +11 more
2024Nature Medicine0 citations Open access
Semantic Scholar
Abstract 5746: Flexible tumor-specific cytokine and antigen delivery through the T-SIGn vector platform enables effective CAR-T cell therapy against solid tumors
M. Sasso, R. Bergin, R. Lear, D. Plumb +9 more
2023Cancer Research0 citations
Semantic Scholar
555 Clinical and pharmacodynamic biomarker results from PORTER, a multi-cohort phase 1 platform trial of combination immunotherapy for metastatic castration-resistant prostate cancer patients
M. Galsky, K. Autio, K. Wentzel, J. Graff +34 more
2022Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
559 Biomarker correlates of clinical response with FLT3L/nivo backbone treatment in the multi-cohort phase 1 PORTER platform trial in metastatic castration-resistant prostate cancer patients
Kristin M. Shotts, Timothy R. Howes, Jia Yu, Julie Densmore +28 more
2022Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
1223 NG-796A: A T-SIGn vector designed to reprogram the tumor microenvironment and drive anti-tumor immunity
M. Zonca, K. West, Carla Cerqueira, A. Muntzer +8 more
2022Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
811 Allelic variation in Human Leukocyte Antigen class II genes is associated with pneumonitis risk in cancer patients treated with immune checkpoint inhibitors
A. Saha, C. Spencer, Zia Khan, J. Carroll +11 more
2021Journal for ImmunoTherapy of Cancer0 citations Open access
Semantic Scholar

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