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R. Esfandiary · SciRah

Researcher profile · Semantic Scholar

R. Esfandiary

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R. Esfandiary — researcher profile on SciRah

h-index: 21
Works: 44
Citations: 1,769

Most-cited papers

Protein-excipient interactions: mechanisms and biophysical characterization applied to protein formulation development.
Tim J. Kamerzell, R. Esfandiary, S. Joshi, C. Middaugh +1 more
2011Advanced Drug Delivery Reviews482 citations
Semantic Scholar
Structural Characterization of IgG1 mAb Aggregates and Particles Generated under Various Stress Conditions
Srivalli N. Telikepalli, Ozan S. Kumru, Cavan Kalonia, R. Esfandiary +3 more
2014Journal of Pharmacy and Science129 citations Open access
Semantic Scholar
Mechanism of reversible self-association of a monoclonal antibody: role of electrostatic and hydrophobic interactions.
R. Esfandiary, A. Parupudi, J. Casas-Finet, Dhanesh Gadre +1 more
2015Journal of Pharmacy and Science109 citations Open access
Semantic Scholar
Comparison of polysorbate 80 hydrolysis and oxidation on the aggregation of a monoclonal antibody.
Nicholas R. Larson, Yang-Jie Wei, Indira Prajapati, A. Chakraborty +8 more
2019Journal of Pharmacy and Science97 citations Open access
Semantic Scholar
Charge-mediated Fab-Fc interactions in an IgG1 antibody induce reversible self-association, cluster formation, and elevated viscosity
Jayant Arora, Yue Hu, R. Esfandiary, Hasige A. Sathish +5 more
2016mAbs93 citations Open access
Semantic Scholar
Hydrogen exchange mass spectrometry reveals protein interfaces and distant dynamic coupling effects during the reversible self-association of an IgG1 monoclonal antibody
Jayant Arora, John M. Hickey, Ranajoy Majumdar, R. Esfandiary +5 more
2015mAbs78 citations Open access
Semantic Scholar
Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life
Ranajoy Majumdar, R. Esfandiary, Steven M. Bishop, Hardeep S. Samra +3 more
2015mAbs71 citations Open access
Semantic Scholar
Mitigation of reversible self-association and viscosity in a human IgG1 monoclonal antibody by rational, structure-guided Fv engineering
James C. Geoghegan, Ryan L. Fleming, M. Damschroder, Steven M. Bishop +2 more
2016mAbs58 citations Open access
Semantic Scholar
Developability Assessment of Engineered Monoclonal Antibody Variants with a Complex Self-Association Behavior Using Complementary Analytical and in Silico Tools.
Shan Lu, N. Mody, Pietro Sormani, K. Rosenthal +2 more
2018Molecular Pharmaceutics55 citations Open access
Semantic Scholar
Effect of Freezing on Lyophilization Process Performance and Drug Product Cake Appearance.
R. Esfandiary, Shravan K. Gattu, J. M. Stewart, S. Patel
2016Journal of Pharmacy and Science53 citations
Semantic Scholar
Utility of High Throughput Screening Techniques to Predict Stability of Monoclonal Antibody Formulations During Early Stage Development.
D. S. Goldberg, R. Lewus, R. Esfandiary, David Farkas +6 more
2017Journal of Pharmacy and Science43 citations
Semantic Scholar
A systematic multitechnique approach for detection and characterization of reversible self-association during formulation development of therapeutic antibodies.
R. Esfandiary, D. Hayes, A. Parupudi, J. Casas-Finet +4 more
2013Journal of Pharmacy and Science40 citations
Semantic Scholar
Temperature dependent 2nd derivative absorbance spectroscopy of aromatic amino acids as a probe of protein dynamics
R. Esfandiary, J. Hunjan, G. Lushington, S. Joshi +1 more
2009Protein Science40 citations Open access
Semantic Scholar
Structural stability of vault particles.
R. Esfandiary, V. Kickhoefer, L. H. Rome, S. Joshi +1 more
2009Journal of Pharmacy and Science40 citations
Semantic Scholar
Towards more tolerable subcutaneous administration: Review of contributing factors for improving combination product design.
N. Mathias, S. Huille, Marie Picci, R. Mahoney +14 more
2024Advanced Drug Delivery Reviews38 citations Open access
Semantic Scholar
Preformulation characterization of an aluminum salt-adjuvanted trivalent recombinant protein-based vaccine candidate against Streptococcus pneumoniae.
Vidyashankara G. Iyer, Lei Hu, Mangala Roshan Liyanage, R. Esfandiary +6 more
2012Journal of Pharmacy and Science32 citations Open access
Semantic Scholar
The effect of PEGylation on the stability of small therapeutic proteins
T. Palm, R. Esfandiary, R. Gandhi
2011Pharmaceutical development and technology (Print)30 citations
Semantic Scholar
A systematic multitechnique approach for detection and characterization of reversible self-association during formulation development of therapeutic antibodies.
R. Esfandiary, D. Hayes, A. Parupudi, J. Casas-Finet +4 more
2013Journal of Pharmacy and Science29 citations Open access
Semantic Scholar
Characterization of Excipient Effects on Reversible Self-association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 1.
Yue Hu, Jayant Arora, S. Joshi, R. Esfandiary +3 more
2019Journal of Pharmacy and Science26 citations
Semantic Scholar
Arginine to lysine mutations increase the aggregation stability of a single chain variable fragment through unfolded state interactions.
James I. Austerberry, A. Thistlethwaite, K. Fisher, A. Golovanov +6 more
2019Biochemistry26 citations Open access
Semantic Scholar
Evaluation of Hydrogen Exchange Mass Spectrometry as a Stability-Indicating Method for Formulation Excipient Screening for an IgG4 Monoclonal Antibody.
Ronald T. Toth, Samantha E. Pace, Brittney J. Mills, S. Joshi +4 more
2017Journal of Pharmacy and Science23 citations
Semantic Scholar
Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies
A. Dippel, Austin Gallegos, V. Aleti, Arnita S. Barnes +28 more
2022mAbs21 citations Open access
Semantic Scholar
Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions
S. Chaturvedi, A. Parupudi, Kristian Juul-Madsen, Ai Nguyen +5 more
2020mAbs19 citations Open access
Semantic Scholar
Empirical Correction for Differences in Chemical Exchange Rates in Hydrogen Exchange-Mass Spectrometry Measurements.
Ronald T. Toth, Brittney J. Mills, S. Joshi, R. Esfandiary +4 more
2017Analytical Chemistry19 citations
Semantic Scholar
Cis/trans isomerization of unsaturated fatty acids in polysorbate 80 during light exposure of a monoclonal antibody-containing formulation.
Indira Prajapati, Björn-Hendrik Peters, Nicholas R. Larson, Yang-Jie Wei +6 more
2019Journal of Pharmacy and Science18 citations Open access
Semantic Scholar
Formulation and immunogenicity of a potential multivalent type III secretion system-based protein vaccine.
Aaron P. Markham, Brooke S. Barrett, R. Esfandiary, W. Picking +3 more
2010Journal of Pharmacy and Science17 citations
Semantic Scholar
Electrostatically Driven Protein-Protein Interactions: Quantitative Prediction of Second Osmotic Virial Coefficients to Aid Antibody Design.
Hassan Shahfar, Qun-le Du, A. Parupudi, Shan Lu +2 more
2022Journal of Physical Chemistry Letters14 citations
Semantic Scholar
Characterization of Excipient Effects on Reversible Self-association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 2.
Yue Hu, Ronald T. Toth, S. Joshi, R. Esfandiary +3 more
2019Journal of Pharmacy and Science10 citations
Semantic Scholar
Formulation and Immunogenicity studies of Type III Secretion System needle antigens as Vaccine Candidates
Brooke S. Barrett, Aaron P. Markham, R. Esfandiary, W. Picking +3 more
2010Journal of Pharmacy and Science10 citations Open access
Semantic Scholar
Conformational Changes and Drivers of Monoclonal Antibody Liquid-Liquid Phase Separation
Nicholas R. Larson, Yang-Jie Wei, T. A. Cruz, R. Esfandiary +3 more
2022Journal of Pharmacy and Science7 citations Open access
Semantic Scholar
Global multi-method analysis of interaction parameters for reversibly self-associating macromolecules at high concentrations
A. Parupudi, S. Chaturvedi, Regina C. Adão, Robert W. Harkness +5 more
2021Scientific Reports7 citations Open access
Semantic Scholar
Biophysical characterization of rotavirus serotypes G1, G3, and G4
R. Esfandiary, Luisa Yee, S. Ohtake, Russell A. Martin +5 more
2010Human Vaccines7 citations Open access
Semantic Scholar
The Use of a GroEL-BLI Biosensor to Rapidly Assess Preaggregate Populations for Antibody Solutions Exhibiting Different Stability Profiles.
Samantha E. Pace, S. Joshi, R. Esfandiary, Robert Stadelman +4 more
2018Journal of Pharmacy and Science6 citations
Semantic Scholar
Enhanced rational protein engineering to reduce viscosity in high-concentration IgG1 antibody solutions
T. Lefevre, Jenna G. Caldwell, Austin Gallegos, Qun Du +3 more
2025mAbs5 citations Open access
Semantic Scholar
Visible Light Degradation of a Monoclonal Antibody in a High-Concentration Formulation: Characterization of a Tryptophan-Derived Chromophoric Photo-product by Comparison to Photo-degradation of N-Acetyl-l-tryptophan Amide.
Indira Prajapati, Nicholas R. Larson, Suresh Choudhary, Cavan Kalonia +4 more
2021Molecular Pharmaceutics5 citations
Semantic Scholar
Refolding and purification of cGMP-grade recombinant human neurturin from Escherichia coli inclusion bodies.
Guo-Ling Xi, R. Esfandiary, C. B. Sacramento, H. Jouihan +3 more
2019Protein Expression and Purification5 citations
Semantic Scholar
Activated mesenchymal stem cells increase drug susceptibility of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa
R. Esfandiary, Pardis Saeedi, Parvaneh Saffarian, R. Halabian +1 more
2023Folia Microbiologica (Prague)4 citations
Semantic Scholar
Improved Comparative Signature Diagrams to Evaluate Similarity of Storage Stability Profiles of Different IgG1 mAbs.
Jae Hyun Kim, S. Joshi, R. Esfandiary, Vidyashankara G. Iyer +3 more
2016Journal of Pharmacy and Science4 citations Open access
Semantic Scholar
Correction to Empirical Correction for Differences in Chemical Exchange Rates in Hydrogen Exchange-Mass Spectrometry Measurements.
Ronald T. Toth, Brittney J. Mills, S. Joshi, R. Esfandiary +4 more
2017Analytical Chemistry3 citations
Semantic Scholar
Role of Acoustic Value Histogram of Urinary Stone on Ultrasonography as Predictor of amenability to Extracorporeal Shock Wave Lithotripsy
H. Talari, Y. Hamidian, R. Esfandiary
20140 citations Open access
Semantic Scholar
A RARE CASE OF AN ISOLATED PELVIC HYDATID CYST IN A 16-YEAR-OLD PATIENT (CASE REPORT)
H. Talari, N. Mousavi, R. Esfandiary, T. Khamechian
20130 citations
Semantic Scholar
A rare case of an isolated pelvic hydatid cyst in a 16-year-old patient
H. Talari, N. Mousavi, R. Esfandiary, T. Khamechian
20130 citations
Semantic Scholar
Understanding Structural Stability of Pharmaceutically Relevant Macromolecular Complexes: A Biophysical and Biochemical Approach
R. Esfandiary
20090 citations
Semantic Scholar
BIOTECHNOLOGY Structural Stability of Vault Particles
R. Esfandiary, V. Kickhoefer, L. H. Rome, S. Joshi +1 more
20090 citations
Semantic Scholar

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