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Anthony P. DeFeo · SciRah

Researcher profile · Semantic Scholar

Anthony P. DeFeo

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Anthony P. DeFeo — researcher profile on SciRah

h-index: 12
Works: 21
Citations: 980

Most-cited papers

TALEN-based gene correction for epidermolysis bullosa.
Mark J. Osborn, Colby G. Starker, A. McElroy, Beau R. Webber +13 more
2013Molecular Therapy283 citations Open access
Semantic Scholar
Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases.
Mark J. Osborn, Beau R. Webber, Friederike Knipping, Cara-Lin Lonetree +18 more
2016Molecular Therapy190 citations Open access
Semantic Scholar
Fanconi Anemia Gene Editing by the CRISPR/Cas9 System
Mark J. Osborn, R. Gabriel, Beau R. Webber, Anthony P. DeFeo +10 more
2015Human Gene Therapy118 citations Open access
Semantic Scholar
CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa
Beau R. Webber, Mark J. Osborn, A. McElroy, K. Twaroski +11 more
2016npj Regenerative Medicine89 citations Open access
Semantic Scholar
Minicircle DNA-based Gene Therapy Coupled With Immune Modulation Permits Long-term Expression of α-l-Iduronidase in Mice With Mucopolysaccharidosis Type I
Mark J. Osborn, Ron T. McElmurry, Christopher J. Lees, Anthony P. DeFeo +6 more
200582 citations
Semantic Scholar
Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial.
E. Lou, M. Choudhry, T. Starr, Timothy D. Folsom +29 more
2025The Lancet Oncology53 citations
Semantic Scholar
Minicircle DNA-based gene therapy coupled with immune modulation permits long-term expression of α-L-iduronidase in mice with mucopolysaccharidosis type I.
Mark J. Osborn, Ron T. McElmurry, Christopher J. Lees, Anthony P. DeFeo +6 more
2011Molecular Therapy36 citations Open access
Semantic Scholar
CRISPR/Cas9 Targeted Gene Editing and Cellular Engineering in Fanconi Anemia
Mark J. Osborn, Cara-Lin Lonetree, Beau R. Webber, Dharmeshkumar Patel +7 more
2016Stem Cells and Development29 citations Open access
Semantic Scholar
CRISPR/Cas9-Mediated Correction of the FANCD1 Gene in Primary Patient Cells
Karolina Skvarova Kramarzova, Mark J. Osborn, Beau R. Webber, Anthony P. DeFeo +3 more
2017International Journal of Molecular Sciences24 citations Open access
Semantic Scholar
Synthetic Zinc Finger Nuclease Design and Rapid Assembly
Mark J. Osborn, Anthony P. DeFeo, B. Blazar, J. Tolar
2011Human Gene Therapy23 citations Open access
Semantic Scholar
Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair
Beau R. Webber, Matthew J. Johnson, Joseph G. Skeate, Nicholas J. Slipek +12 more
2023Nature Biomedical Engineering21 citations Open access
Semantic Scholar
Angiotensin receptor blockade mediated amelioration of mucopolysaccharidosis type I cardiac and craniofacial pathology
Mark J. Osborn, Beau R. Webber, Ron T. McElmurry, K. Rudser +7 more
2016Journal of Inherited Metabolic Disease14 citations Open access
Semantic Scholar
Correction of Fanconi Anemia Mutations Using Digital Genome Engineering
Christopher J. Sipe, Mitchell G. Kluesner, S. Bingea, Walker S. Lahr +13 more
2022International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Clinical manufacture of CRISPR/Cas9-based cytokine-induced SH2 protein knock-out tumor-infiltrating lymphocytes for gastrointestinal cancers.
Matthew J. Johnson, D. Sumstad, Timothy D. Folsom, Nicholas J. Slipek +10 more
2025Cytotherapy6 citations
Semantic Scholar
400 Modeling osteosarcoma progression and therapeutic response using engineered induced pluripotent stem cell-derived 3D organoids
Sophia Wenthe, Rebecca A. Johnson, Kelsie L. Becklin, Nicholas J. Slipek +7 more
2026Journal of Clinical and Translational Science1 citations Open access
Semantic Scholar
Abstract CT269: First-in-human trial in patients with metastatic colorectal cancer using CRISPR-engineered tumor infiltrating lymphocytes in which the intracellular immune checkpoint CISH is inhibited
E. Lou, Modassir Choudhry, Timothy K. Starr, Timothy D. Folsom +29 more
2025Cancer Research1 citations
Semantic Scholar
Homology mediated end joining enables efficient non-viral targeted integration of large DNA templates in primary human T cells
Beau R. Webber, Matthew J. Johnson, Nicholas J. Slipek, Walker S. Lahr +10 more
2021bioRxiv1 citations Open access
Semantic Scholar
Elucidating mechanisms of deletional and non-deletional CD8+ T cell tolerance 3250
Katharine E. Block, E. Truckenbrod, Hristo Georgiev, Anthony P. DeFeo +3 more
2025Journal of Immunology0 citations
Semantic Scholar
Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates.
Matthew J. Johnson, Anthony P. DeFeo, Nicholas J. Slipek, Timothy D. Folsom +4 more
2025Journal of Visualized Experiments0 citations
Semantic Scholar
371 CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa (RDEB)
Mark J. Osborn, Beau R. Webber, A. McElroy, Anthony P. DeFeo +6 more
20160 citations Open access
Semantic Scholar
Megatal, Crispr/Cas9, and Talen T-Cell Receptor Gene Editing
Mark J. Osborn, Beau R. Webber, Friederike Knipping, Cara-Lin Lonetree +15 more
20150 citations
Semantic Scholar

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Beau R. Webber×15
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