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Walker S. Lahr · SciRah

Researcher profile · Semantic Scholar

Walker S. Lahr

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Walker S. Lahr — researcher profile on SciRah

h-index: 16
Works: 41
Citations: 1,577

Most-cited papers

EditR: A Method to Quantify Base Editing from Sanger Sequencing
Mitchell G. Kluesner, Derek A. Nedveck, Walker S. Lahr, J. Garbe +3 more
2018The CRISPR Journal445 citations Open access
Semantic Scholar
Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors
Beau R. Webber, Cara-Lin Lonetree, Mitchell G. Kluesner, Matthew J. Johnson +11 more
2018Nature Communications216 citations Open access
Semantic Scholar
A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy
Emily J. Pomeroy, John T. Hunzeker, Mitchell T. Kluesner, Walker S. Lahr +12 more
2018bioRxiv166 citations Open access
Semantic Scholar
Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments
Erdem D. Tabdanov, Nelson J. Rodríguez-Merced, Alexander X. Cartagena-Rivera, V. Puram +9 more
2020Nature Communications125 citations Open access
Semantic Scholar
CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells
Mitchell G. Kluesner, Walker S. Lahr, Cara-Lin Lonetree, B. Smeester +11 more
2021Nature Communications100 citations Open access
Semantic Scholar
A BAFF ligand-based CAR-T cell targeting three receptors and multiple B cell cancers
Derek P. Wong, N. Roy, Keman Zhang, A. Anukanth +9 more
2022Nature Communications80 citations Open access
Semantic Scholar
Engineering of Primary Human B cells with CRISPR/Cas9 Targeted Nuclease
Matthew J. Johnson, Kanut Laoharawee, Walker S. Lahr, Beau R. Webber +1 more
2018Scientific Reports70 citations Open access
Semantic Scholar
Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays
M. Kurata, Natalie K. Wolf, Walker S. Lahr, Madison T. Weg +6 more
2018bioRxiv65 citations Open access
Semantic Scholar
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
D. Palmer, Beau R. Webber, Y. Patel, Matthew J. Johnson +34 more
2020bioRxiv57 citations Open access
Semantic Scholar
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
D. Palmer, Beau R. Webber, Yogin Patel, Matthew J. Johnson +34 more
2022i Medicina40 citations Open access
Semantic Scholar
Evolution of the clinical-stage hyperactive TcBuster transposase as a platform for robust non-viral production of adoptive cellular therapies
Joseph G. Skeate, Emily J. Pomeroy, Nicholas J. Slipek, B. Jones +20 more
2024Molecular Therapy29 citations Open access
Semantic Scholar
Engineering CD70-Directed CAR-NK Cells for the Treatment of Hematological and Solid Malignancies
Eugene Choi, J. Chang, Joshua B. Krueger, Walker S. Lahr +11 more
2021Blood25 citations Open access
Semantic Scholar
Precision enhancement of CAR-NK cells through non-viral engineering and highly multiplexed base editing
Min-Jing Wang, Joshua B. Krueger, Alexandria K. Gilkey, Erin M. Stelljes +14 more
2025Journal for ImmunoTherapy of Cancer24 citations Open access
Semantic Scholar
CRISPR-Cas9 base editors and their future role in human therapeutics
Walker S. Lahr, Christopher J. Sipe, Joseph G. Skeate, Beau R. Webber +1 more
2023Cytotherapy21 citations Open access
Semantic Scholar
Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair
Beau R. Webber, Matthew J. Johnson, Joseph G. Skeate, Nicholas J. Slipek +12 more
2023Nature Biomedical Engineering21 citations Open access
Semantic Scholar
Precision Enhancement of CAR-NK Cells through Non-Viral Engineering and Highly Multiplexed Base Editing
Min-Jing Wang, Joshua B. Krueger, Alexandria K. Gilkey, Erin M. Stelljes +11 more
2024bioRxiv18 citations Open access
Semantic Scholar
333 Targeting the apical intracellular checkpoint CISH unleashes T cell neoantigen reactivity and effector program
D. Palmer, Beau R. Webber, Y. Patel, Matthew D. Johnson +34 more
2020Journal for ImmunoTherapy of Cancer13 citations Open access
Semantic Scholar
Correction of Fanconi Anemia Mutations Using Digital Genome Engineering
Christopher J. Sipe, Mitchell G. Kluesner, S. Bingea, Walker S. Lahr +13 more
2022International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Non-Viral Engineering of CAR-NK and CAR-T cells using the Tc Buster Transposon System™
Emily J. Pomeroy, Walker S. Lahr, J. Chang, Joshua B. Krueger +5 more
2021bioRxiv11 citations Open access
Semantic Scholar
Germline T cell receptor exchange results in physiological T cell development and function
M. Rollins, Jackson F. Raynor, Ebony A. Miller, Jonah Z Butler +7 more
2023Nature Communications9 citations Open access
Semantic Scholar
Genome Engineering Primary Human B Cells Using CRISPR/Cas9.
Kanut Laoharawee, Matthew J. Johnson, Walker S. Lahr, Joseph J. Peterson +2 more
2020Journal of Visualized Experiments8 citations Open access
Semantic Scholar
Author Correction: Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors
Beau R. Webber, Cara-Lin Lonetree, Mitchell G. Kluesner, Matthew J. Johnson +11 more
2019Nature Communications6 citations Open access
Semantic Scholar
EditR: A novel base editing quantification software using Sanger sequencing
Mitchell G. Kluesner, Derek A. Nedveck, Walker S. Lahr, J. Garbe +3 more
2017bioRxiv6 citations Open access
Semantic Scholar
A Pan-RNase Inhibitor Enabling CRISPR-mRNA Platforms for Engineering of Primary Human Monocytes
Kanut Laoharawee, Matthew J. Johnson, Walker S. Lahr, Christopher J. Sipe +8 more
2022International Journal of Molecular Sciences5 citations Open access
Semantic Scholar
CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary cells
Mitchell G. Kluesner, Walker S. Lahr, Cara-Lin Lonetree, B. Smeester +8 more
2020bioRxiv5 citations Open access
Semantic Scholar
A Singular Base Editing Platform for Polyfunctional Multiplex Engineering of Immune Cells
Joseph G. Skeate, Nicholas J. Slipek, Walker S. Lahr, Shambojit Roy +15 more
2025bioRxiv2 citations
Semantic Scholar
Multiplex Human T Cell Engineering without Double-Strand Break Induction Using the Cas9 Base Editor System
Beau R. Webber, Cara-Lin Lonetree, Miechaleen D. Diers, Walker S. Lahr +3 more
2018Blood2 citations Open access
Semantic Scholar
Abstract A021: Chimeric antigen receptor armored natural killer cell immunotherapy for osteosarcoma
Gabrielle M. Robbins, Kenta Yamomoto, Walker S. Lahr, Joseph G. Skeate
2022Clinical Cancer Research1 citations
Semantic Scholar
Homology mediated end joining enables efficient non-viral targeted integration of large DNA templates in primary human T cells
Beau R. Webber, Matthew J. Johnson, Nicholas J. Slipek, Walker S. Lahr +10 more
2021bioRxiv1 citations Open access
Semantic Scholar
Efficient, fratricide free non-viral engineering of CD70-targeted CAR NK cells for hematologic and solid tumor immunotherapy
J. Chang, Joshua B. Krueger, Timothy D. Folsom, Joseph G. Skeate +6 more
2026Molecular therapy. Advances0 citations Open access
Semantic Scholar
A Singular Base Editing Platform for Polyfunctional Multiplex Engineering of Immune Cells.
Joseph G. Skeate, Nicholas J. Slipek, Walker S. Lahr, Shambojit Roy +16 more
2026Molecular Therapy0 citations Open access
Semantic Scholar
347 Highly multiplexed engineering of immune effector cells for advanced cancer therapies
Joseph G. Skeate, Min-Jing Wang, Joshua B. Krueger, Alexandria K. Gilkey +10 more
2024Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Development and testing of a versatile genome editing application reporter (V-GEAR) system
Evan W. Kleinboehl, Kanut Laoharawee, Walker S. Lahr, Jacob D. Jensen +4 more
2024Molecular Therapy: Methods & Clinical Development0 citations Open access
Semantic Scholar
3145 – TRANSIENT EXPRESSION OF HEMATOPOIETIC TRANSCRIPTION FACTORS ENHANCES T CELL POTENTIAL OF HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED HEMATOPOIETIC PROGENITORS
B. Napiwocki, Walker S. Lahr, B. Moriarity, Lage von Dissen +1 more
2022Experimental Hematology0 citations Open access
Semantic Scholar
A BAFF ligand-based CAR-T cell targeting three receptors and multiple B cell cancers
Derek P. Wong, N. Roy, Keman Zhang, A. Anukanth +9 more
2022Nature Communications0 citations Open access
Semantic Scholar
Abstract 2836: Genome engineered natural killer cell immunotherapy against osteosarcoma
Gabrielle M. Robbins, Kenta Yamamoto, Joshua B. Krueger, Walker S. Lahr +2 more
2022Cancer Research0 citations
Semantic Scholar
Abstract PO010: Engineering T cells to enhance 3D migration through mechanically and structurally complex tumor microenvironments
Erdem D. Tabdanov, Nelson J. Rodríguez-Merced, Alexander X. Cartagena-Rivera, V. Puram +9 more
2021Immune Tumor Microenvironment: Blood-Derived versus Tissue-Resident0 citations
Semantic Scholar
659 T cell receptor exchange by zygote engineering results in physiological T cell responses for therapeutic use in pancreatic ductal adenocarcinoma
M. Rollins, Jackson F. Raynor, Ebony A. Miller, Ellen J. Spartz +6 more
2021Journal for ImmunoTherapy of Cancer0 citations Open access
Semantic Scholar
Genome Engineering Primary Human B Cells Using CRISPR/ Cas9.
Kanut Loaharawee, Matthew J. Johnson, Walker S. Lahr, S. Joseph +3 more
20210 citations
Semantic Scholar
35 Targeted non-viral integration of large cargo in primary human T cells by CRISPR/Cas9 guided homology mediated end joining
Beau R. Webber, Matthew D. Johnson, Nicholas J. Slipek, Walker S. Lahr +6 more
2020Journal for ImmunoTherapy of Cancer0 citations Open access
Semantic Scholar
Abstract A036: Multiplex human T-cell engineering by Cas9 base editor technology
Cara-Lin Lonetree, Beau R. Webber, Miechaleen D. Diers, Walker S. Lahr +4 more
2019Genetically Engineered T-cells0 citations
Semantic Scholar

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Beau R. Webber×39
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B. Moriarity×38
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Nicholas J. Slipek×18
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Mitchell G. Kluesner×14
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Mitchell G. Kluesner — researcher profile on SciRah

Emily J. Pomeroy×13

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Emily J. Pomeroy — researcher profile on SciRah

Joseph G. Skeate×13

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Miechaleen D. Diers×12

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Joshua B. Krueger×10

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Cara-Lin Lonetree×9

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Matthew J. Johnson×9

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Kanut Laoharawee×7

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