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Zhiyuan Wu · SciRah

Researcher profile · Semantic Scholar

Zhiyuan Wu

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Zhiyuan Wu — researcher profile on SciRah

h-index: 27
Works: 50
Citations: 2,501

Most-cited papers

Role of Endothelial Dysfunction in Cardiovascular Diseases: The Link Between Inflammation and Hydrogen Sulfide
Hai-Jian Sun, Zhiyuan Wu, Xiaowei Nie, J. Bian
2020Frontiers in Pharmacology494 citations Open access
Semantic Scholar
Hydrogen Sulfide Inhibits Rotenone-Induced Apoptosis via Preservation of Mitochondrial Function
Li-Fang Hu, Ming Lu, Zhiyuan Wu, P. T. Wong +1 more
2009Molecular Pharmacology249 citations
Semantic Scholar
Polysulfide-mediated sulfhydration of SIRT1 prevents diabetic nephropathy by suppressing phosphorylation and acetylation of p65 NF-κB and STAT3
Hai-Jian Sun, Siping Xiong, Xu Cao, Lei Cao +3 more
2020Redox Biology222 citations Open access
Semantic Scholar
Hydrogen sulfide protects MC3T3-E1 osteoblastic cells against H2O2-induced oxidative damage-implications for the treatment of osteoporosis.
Zhong-Shi Xu, Xin-Yu Wang, De-Ming Xiao, Li-Fang Hu +3 more
2011Free Radical Biology & Medicine179 citations
Semantic Scholar
Sulfhydration of p66Shc at Cysteine59 Mediates the Antioxidant Effect of Hydrogen Sulfide
Zhi-Zhong Xie, Meimei Shi, Li Xie, Zhiyuan Wu +3 more
2014Antioxidants and Redox Signaling131 citations Open access
Semantic Scholar
Implications of hydrogen sulfide in liver pathophysiology: Mechanistic insights and therapeutic potential
Hai-Jian Sun, Zhiyuan Wu, Xiaowei Nie, Xin-Yu Wang +1 more
2020Journal of Advanced Research83 citations Open access
Semantic Scholar
Hydrogen Sulfide: Recent Progression and Perspectives for the Treatment of Diabetic Nephropathy
Hai-Jian Sun, Zhiyuan Wu, Lei Cao, Mengyuan Zhu +5 more
2019Molecules79 citations Open access
Semantic Scholar
Renal protective effect of polysulfide in cisplatin-induced nephrotoxicity
Xu Cao, Xiao-Wei Nie, Siping Xiong, Lei Cao +3 more
2018Redox Biology67 citations Open access
Semantic Scholar
Hydrogen Sulfide Prevents Elastin Loss and Attenuates Calcification Induced by High Glucose in Smooth Muscle Cells through Suppression of Stat3/Cathepsin S Signaling Pathway
Ye-Bo Zhou, Hong Zhou, Li Li, Ying Kang +5 more
2019International Journal of Molecular Sciences57 citations Open access
Semantic Scholar
Hydrogen sulfide inhibits ATP-induced neuroinflammation and Aβ1-42 synthesis by suppressing the activation of STAT3 and cathepsin S.
Lei Cao, Xu Cao, Yebo Zhou, B. V. Nagpure +6 more
2018Brain, behavior, and immunity57 citations
Semantic Scholar
Role of Hydrogen Sulfide and Polysulfides in Neurological Diseases: Focus on Protein S-Persulfidation
Hai-Jian Sun, Zhiyuan Wu, Xiaowei Nie, J. Bian
2020Current Neuropharmacology50 citations Open access
Semantic Scholar
Progesterone Impairs Human Ether-a-go-go-related Gene (HERG) Trafficking by Disruption of Intracellular Cholesterol Homeostasis*
Zhiyuan Wu, De-Jie Yu, T. Soong, G. Dawe +1 more
2011Journal of Biological Chemistry43 citations Open access
Semantic Scholar
Hydrogen Sulfide Attenuates Opioid Dependence by Suppression of Adenylate Cyclase/cAMP Pathway
Hai-Yu Yang, Zhiyuan Wu, M. Wood, M. Whiteman +1 more
2014Antioxidants and Redox Signaling42 citations Open access
Semantic Scholar
Anti–Na+/K+-ATPase immunotherapy ameliorates α-synuclein pathology through activation of Na+/K+-ATPase α1–dependent autophagy
Lei Cao, Siping Xiong, Zhiyuan Wu, Lei Ding +6 more
2021Science Advances41 citations Open access
Semantic Scholar
Induction of caveolin-3/eNOS complex by nitroxyl (HNO) ameliorates diabetic cardiomyopathy
Hai-Jian Sun, Siping Xiong, Zhiyuan Wu, Lei Cao +3 more
2020Redox Biology40 citations Open access
Semantic Scholar
The New Synthetic H2S-Releasing SDSS Protects MC3T3-E1 Osteoblasts against H2O2-Induced Apoptosis by Suppressing Oxidative Stress, Inhibiting MAPKs, and Activating the PI3K/Akt Pathway
Xiao-Fei Yan, Haixia Wu, Zhiyuan Wu, Fei Hua +5 more
2017Frontiers in Pharmacology39 citations Open access
Semantic Scholar
Renal Protective Effect of Hydrogen Sulfide in Cisplatin-Induced Nephrotoxicity
Xu Cao, Siping Xiong, Yebo Zhou, Zhiyuan Wu +6 more
2018Antioxidants and Redox Signaling36 citations
Semantic Scholar
Hydrogen sulfide reduces RAGE toxicity through inhibition of its dimer formation
Hong Zhou, Lei Ding, Zhiyuan Wu, Xu Cao +3 more
2017Free Radical Biology & Medicine36 citations
Semantic Scholar
The role of hydrogen sulfide in cyclic nucleotide signaling
Xu Cao, Zhiyuan Wu, Siping Xiong, Lei Cao +2 more
2017Biochemical Pharmacology36 citations
Semantic Scholar
Red blood cell extracellular vesicles deliver therapeutic siRNAs to skeletal muscles for treatment of cancer cachexia
Boya Peng, Yu-Qi Yang, Zhiyuan Wu, Renke Tan +8 more
2023Molecular Therapy35 citations Open access
Semantic Scholar
Polysulfide and Hydrogen Sulfide Ameliorate Cisplatin-Induced Nephrotoxicity and Renal Inflammation through Persulfidating STAT3 and IKKβ
Hai-Jian Sun, Bin Leng, Zhiyuan Wu, J. Bian
2020International Journal of Molecular Sciences35 citations Open access
Semantic Scholar
HNO suppresses LPS-induced inflammation in BV-2 microglial cells via inhibition of NF-κB and p38 MAPK pathways.
Yebo Zhou, Zhiyuan Wu, Xu Cao, Lei Ding +2 more
2016Pharmacological Research34 citations
Semantic Scholar
CD33‐targeting extracellular vesicles deliver antisense oligonucleotides against FLT3‐ITD and miR‐125b for specific treatment of acute myeloid leukaemia
Huan Chen, M. Jayasinghe, E. Y. Yeo, Zhiyuan Wu +10 more
2022Cell Proliferation31 citations Open access
Semantic Scholar
Role of Na+/K+-ATPase in ischemic stroke: in-depth perspectives from physiology to pharmacology
Mengyuan Zhu, Haijian Sun, Lei Cao, Zhiyuan Wu +2 more
2021Journal of molecular medicine31 citations
Semantic Scholar
Na+/K+-ATPase-dependent autophagy protects brain against ischemic injury
Mengyuan Zhu, Lei Cao, Siping Xiong, Haijian Sun +2 more
2020Signal Transduction and Targeted Therapy29 citations Open access
Semantic Scholar
A near infrared singlet oxygen probe and its applications in in vivo imaging and measurement of singlet oxygen quenching activity of flavonoids
Dong Liang, Yuannian Zhang, Zhiyuan Wu, Yong-Jun Chen +5 more
2018Sensors and actuators. B, Chemical29 citations
Semantic Scholar
DR-region of Na+/K+ ATPase is a target to treat excitotoxicity and stroke
Meimei Shi, Lei Cao, Xu Cao, Mengyuan Zhu +8 more
2018Cell Death and Disease29 citations Open access
Semantic Scholar
Stimulation of N-terminal truncated isoform of androgen receptor stabilizes human ether-á-go-go-related gene-encoded potassium channel protein via activation of extracellular signal regulated kinase 1/2.
Zhiyuan Wu, Kun Chen, B. Haendler, T. McDonald +1 more
2008Endocrinology27 citations Open access
Semantic Scholar
Nitroxyl as a Potential Theranostic in the Cancer Arena
Hai-Jian Sun, W. Lee, Bin Leng, Zhiyuan Wu +2 more
2020Antioxidants and Redox Signaling24 citations Open access
Semantic Scholar
An Updated Insight Into Molecular Mechanism of Hydrogen Sulfide in Cardiomyopathy and Myocardial Ischemia/Reperfusion Injury Under Diabetes
Hai-Jian Sun, Zhiyuan Wu, Xiaowei Nie, Xin-Yu Wang +1 more
2021Frontiers in Pharmacology23 citations Open access
Semantic Scholar
Post-Transcriptional Control of Human Ether-a-go-go-Related Gene Potassium Channel Protein by α-Adrenergic Receptor Stimulation
Jian Chen, Kun Chen, Jakub Sroubek, Zhiyuan Wu +3 more
2010Molecular Pharmacology23 citations Open access
Semantic Scholar
Role of nitroxyl (HNO) in cardiovascular system: From biochemistry to pharmacology.
Hai-Jian Sun, Zhiyuan Wu, Lei Cao, Mengyuan Zhu +4 more
2020Pharmacological Research22 citations
Semantic Scholar
DR-region of Na+/K+-ATPase is a target to ameliorate hepatic insulin resistance in obese diabetic mice
Hai-Jian Sun, Lei Cao, Mengyuan Zhu, Zhiyuan Wu +3 more
2020Theranostics22 citations Open access
Semantic Scholar
DR region of Na+-K+-ATPase is a new target to protect heart against oxidative injury
Fei Hua, Zhiyuan Wu, Xiao-Fei Yan, Jin Zheng +3 more
2018Scientific Reports22 citations Open access
Semantic Scholar
DR region of NKAα1 is a target to ameliorate hepatic lipid metabolism disturbance in obese mice.
Hai-Jian Sun, Jian-Xin Tan, Xiaodong Shan, Z. Wang +3 more
2023Metabolism: Clinical and Experimental21 citations
Semantic Scholar
Stimulation of Na+/K+-ATPase with an Antibody against Its 4th Extracellular Region Attenuates Angiotensin II-Induced H9c2 Cardiomyocyte Hypertrophy via an AMPK/SIRT3/PPARγ Signaling Pathway
Siping Xiong, Hai-Jian Sun, Lei Cao, Mengyuan Zhu +3 more
2019Oxidative Medicine and Cellular Longevity19 citations Open access
Semantic Scholar
Polysulfide Protects Against Diabetic Cardiomyopathy Through Sulfhydration of Peroxisome Proliferator-Activated Receptor-γ and Sirtuin 3
Siping Xiong, Haijian Sun, Xu Cao, Zhiyuan Wu +4 more
2022Antioxidants and Redox Signaling15 citations
Semantic Scholar
Hydrogen sulfide inhibits opioid withdrawal-induced pain sensitization in rats by down-regulation of spinal calcitonin gene-related peptide expression in the spine.
Hai-Yu Yang, Zhiyuan Wu, J. Bian
2014International Journal of Neuropsychopharmacology14 citations Open access
Semantic Scholar
Immunization with Na+/K+ ATPase DR peptide prevents bone loss in an ovariectomized rat osteoporosis model
Siping Xiong, X. Yang, Xiao-Fei Yan, Fei Hua +4 more
2018Biochemical Pharmacology10 citations
Semantic Scholar
A Newly Synthesized Flavone from Luteolin Escapes from COMT-Catalyzed Methylation and Inhibits Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages via JNK, p38 and NF-κB Signaling Pathways
Lin Ye, Y. Xin, Zhiyuan Wu, Hai-Jian Sun +2 more
2021Journal of Microbiology and Biotechnology9 citations Open access
Semantic Scholar
Three-Dimensional RAW264.7 Cell Model on Electrohydrodynamic Printed Poly(ε-Caprolactone) Scaffolds for In Vitro Study of Anti-Inflammatory Compounds.
Xiang Wang, Yujia Cao, Linzhi Jing, Siyu Chen +7 more
2021ACS Applied Bio Materials9 citations
Semantic Scholar
Post-Transcriptional Control of Human Ether-a-go-go-Related Gene Potassium Channel Protein by (cid:1) -Adrenergic Receptor Stimulation
Jian Chen, Kun Chen, Jakub Sroubek, Zhiyuan Wu +3 more
20105 citations
Semantic Scholar
The Role of H2S in the Metabolism of Glucose and Lipids.
Hai-Jian Sun, Zhiyuan Wu, Xiaowei Nie, J. Bian
2021Advances in Experimental Medicine and Biology2 citations
Semantic Scholar
Post-transcriptional control of HERG potassium channel protein by α -adrenergic receptor stimulation.
Jian Chen, Kun Chen, Jakub Sroubek, Zhiyuan Wu +4 more
20102 citations
Semantic Scholar
P38 Hydrogen sulfide regulates cardiac function via S-sulfhydration of adenylyl cyclase
Zhiyuan Wu, Gerhard Grüber, J. Bian
20121 citations
Semantic Scholar
P63: Hydrogen sulfide inhibits opioid withdrawal-induced pain sensitization in rats by down-regulation of CGRP expression in the spine
Hai-Yu Yang, Zhiyuan Wu, J. Bian
20140 citations
Semantic Scholar
Progesterone Impairs the Trafficking and Maturation of HERG Potassium Channels
Zhiyuan Wu, J. Bian
20100 citations Open access
Semantic Scholar
Post-Transcriptional Control of Human Ether-a-go-go-Related Gene Potassium Channel Protein by (cid:1) -Adrenergic Receptor Stimulation
Jian Chen, Kun Chen, Jakub Sroubek, Zhiyuan Wu +3 more
20100 citations
Semantic Scholar
Post-Transcriptional Control of Human Ether-a-go-go-Related Gene Potassium Channel Protein by (cid:1) -Adrenergic Receptor Stimulation
Jian Chen, Kun Chen, Jakub Sroubek, Zhiyuan Wu +3 more
20100 citations
Semantic Scholar
Androgens Stabilize HERG Potassium Channel Protein Via Stimulation Of Androgen Receptor Variant Ar45
Zhiyuan Wu, J. Bian
20090 citations Open access
Semantic Scholar

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J. Bian×38
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Hai-Jian Sun×15
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Lei Cao×12
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Mengyuan Zhu×12
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Xiaowei Nie — researcher profile on SciRah

Siping Xiong×11

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Kun Chen — researcher profile on SciRah

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Lei Ding — researcher profile on SciRah

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Jian Chen — researcher profile on SciRah