D. Moj

Most-cited papers

1. PBPK Models for CYP3A4 and P‐gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and Digoxin

   N. Hanke, S. Frechen, D. Moj, Hannah Britz +3 more

   2018CPT: Pharmacometrics & Systems Pharmacology149 citations Open access

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2. A Physiologically Based Pharmacokinetic Model of Voriconazole Integrating Time-Dependent Inhibition of CYP3A4, Genetic Polymorphisms of CYP2C19 and Predictions of Drug–Drug Interactions

   Xia Li, S. Frechen, D. Moj, T. Lehr +7 more

   2019Clinical Pharmacokinetics58 citations Open access

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3. Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug–Drug Interactions and Co-medication Regimens

   D. Moj, N. Hanke, Hannah Britz, S. Frechen +4 more

   2016AAPS Journal41 citations

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4. A physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model of the histone deacetylase (HDAC) inhibitor vorinostat for pediatric and adult patients and its application for dose specification

   D. Moj, Hannah Britz, J. Burhenne, C. Stewart +3 more

   2017Cancer Chemotherapy and Pharmacology23 citations Open access

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5. A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Model of Dabigatran Etexilate, Dabigatran and Dabigatran Glucuronide in Healthy Adults and Renally Impaired Patients

   D. Moj, H. Maas, A. Schaeftlein, N. Hanke +2 more

   2019Clinical Pharmacokinetics21 citations

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6. A physiologically based pharmacokinetic (PBPK) parent-metabolite model of the chemotherapeutic zoptarelin doxorubicin—integration of in vitro results, Phase I and Phase II data and model application for drug–drug interaction potential analysis

   N. Hanke, M. Teifel, D. Moj, Jan-Georg Wojtyniak +5 more

   2018Cancer Chemotherapy and Pharmacology20 citations

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7. The feasibility of physiologically based pharmacokinetic modeling in forensic medicine illustrated by the example of morphine

   Nadine Schaefer, D. Moj, T. Lehr, P. Schmidt +1 more

   2018Zeitschrift für Rechtsmedizin9 citations

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8. Cascade-free sequences, dispersion index, and state avoidance for stateful digit-wise operations

   D. Moj

   20261 citations

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9. Translational physiologically-based pharmacokinetic (PBPK) modeling and simulation to support drug development and pharmacotherapy

   D. Moj

   20181 citations

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10. Biorthogonal eigenvectors of the Holte carry matrix and cascade-free enumeration

    D. Moj

    20260 citations

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11. Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug–Drug Interactions and Co-medication Regimens

    D. Moj, N. Hanke, Hannah Britz, S. Frechen +4 more

    2016AAPS Journal0 citations

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