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Thomas Wendl · SciRah

Researcher profile · Semantic Scholar

Thomas Wendl

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Thomas Wendl — researcher profile on SciRah

h-index: 16
Works: 27
Citations: 1,431

Most-cited papers

Applied Concepts in PBPK Modeling: How to Build a PBPK/PD Model
L. Kuepfer, Christoph Niederalt, Thomas Wendl, Jan-Frederik Schlender +5 more
2016CPT: Pharmacometrics & Systems Pharmacology383 citations Open access
Semantic Scholar
A Computational Systems Biology Software Platform for Multiscale Modeling and Simulation: Integrating Whole-Body Physiology, Disease Biology, and Molecular Reaction Networks
T. Eissing, L. Kuepfer, C. Becker, Michael Block +17 more
2011Front. Physio.215 citations Open access
Semantic Scholar
Pax2.1 is required for the development of thyroid follicles in zebrafish.
Thomas Wendl, Klaus Lun, M. Mione, J. Favor +3 more
2002Development182 citations
Semantic Scholar
Analysis of origin and growth of the thyroid gland in zebrafish
Burkhard Alt, S. Reibe, N. M. Feitosa, Osama A. Elsalini +2 more
2006Developmental Dynamics154 citations
Semantic Scholar
PBPK Models for CYP3A4 and P‐gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and Digoxin
N. Hanke, S. Frechen, D. Moj, Hannah Britz +3 more
2018CPT: Pharmacometrics & Systems Pharmacology149 citations Open access
Semantic Scholar
Early developmental specification of the thyroid gland depends on han-expressing surrounding tissue and on FGF signals
Thomas Wendl, Dejan Adzic, J. Schoenebeck, Steffen Scholpp +3 more
2007Development66 citations Open access
Semantic Scholar
Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug–Drug–Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole
Denise Türk, N. Hanke, S. Wolf, S. Frechen +4 more
2019Clinical Pharmacokinetics41 citations Open access
Semantic Scholar
Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug–Drug Interactions and Co-medication Regimens
D. Moj, N. Hanke, Hannah Britz, S. Frechen +4 more
2016AAPS Journal41 citations
Semantic Scholar
Physiologically‐Based Pharmacokinetic Models for CYP1A2 Drug–Drug Interaction Prediction: A Modeling Network of Fluvoxamine, Theophylline, Caffeine, Rifampicin, and Midazolam
Hannah Britz, N. Hanke, Anke-Katrin Volz, O. Spigset +5 more
2019CPT: Pharmacometrics & Systems Pharmacology33 citations Open access
Semantic Scholar
A generic framework for the physiologically‐based pharmacokinetic platform qualification of PK‐Sim and its application to predicting cytochrome P450 3A4–mediated drug–drug interactions
S. Frechen, Juri Solodenko, Thomas Wendl, A. Dallmann +4 more
2021CPT: Pharmacometrics & Systems Pharmacology26 citations Open access
Semantic Scholar
DEVELOPMENT AND DISEASE pax 2 . 1 is required for the development of thyroid follicles in zebrafish
Thomas Wendl, Klaus Lun, M. Mione, J. Favor +3 more
200221 citations
Semantic Scholar
Quantitative Assessment of Levonorgestrel Binding Partner Interplay and Drug‐Drug Interactions Using Physiologically Based Pharmacokinetic Modeling
B. Cicali, K. Lingineni, Rodrigo Cristofoletti, Thomas Wendl +5 more
2020CPT: Pharmacometrics & Systems Pharmacology19 citations Open access
Semantic Scholar
Application of Physiologically‐Based and Population Pharmacokinetic Modeling for Dose Finding and Confirmation During the Pediatric Development of Moxifloxacin
S. Willmann, M. Frei, G. Sutter, K. Coboeken +4 more
2019CPT: Pharmacometrics & Systems Pharmacology19 citations Open access
Semantic Scholar
Development of a Physiologically Based Computational Kidney Model to Describe the Renal Excretion of Hydrophilic Agents in Rats
Christoph Niederalt, Thomas Wendl, L. Kuepfer, K. Claassen +9 more
2013Front. Physio.19 citations Open access
Semantic Scholar
Predictive Performance of Physiology‐Based Pharmacokinetic Dose Estimates for Pediatric Trials: Evaluation With 10 Bayer Small‐Molecule Compounds in Children
Ibrahim Ince, A. Dallmann, S. Frechen, K. Coboeken +9 more
2021Journal of clinical pharmacology17 citations Open access
Semantic Scholar
Physiologically‐based pharmacokinetic modeling to predict CYP3A4‐mediated drug‐drug interactions of finerenone
Thomas Wendl, S. Frechen, M. Gerisch, R. Heinig +1 more
2021CPT: Pharmacometrics & Systems Pharmacology16 citations Open access
Semantic Scholar
Determining the Exposure Threshold for Levonorgestrel Efficacy Using an Integrated Model Based Meta‐Analysis Approach
K. Lingineni, A. Chaturvedula, B. Cicali, Rodrigo Cristofoletti +5 more
2021Clinical pharmacology and therapy9 citations
Semantic Scholar
Development of a Translational Exposure‐Bracketing Approach to Streamline the Development of Hormonal Contraceptive Drug Products
B. Cicali, Lais da Silva, A. Sarayani, K. Lingineni +9 more
2022Clinical pharmacology and therapy6 citations
Semantic Scholar
926: RISK ASSESSMENT FOR AMIKACIN INHALE IN ICU PATIENTS USING WHOLE-BODY PHYSIOLOGICALLY-BASED PK-MODELS
H. Stass, S. Willmann, Thomas Wendl
20136 citations
Semantic Scholar
PBPK Modelling of Intracellular Drug Delivery Through Active and Passive Transport Processes
L. Kuepfer, Christoph Niederalt, Thomas Wendl, Jan-Frederik Schlender +3 more
20164 citations
Semantic Scholar
Model-Based Analysis of In Vivo Release Data of Levonorgestrel Implants: Projecting Long-Term Systemic Exposure
Soyoung Kim, B. Cicali, Michelle A Pressly, Lais da Silva +4 more
2023Pharmaceutics2 citations Open access
Semantic Scholar
Harnessing Open‐Source Solutions: Insights From the First Open Systems Pharmacology (OSP) Community Conference
André Dallmann, Denise Feick, Pavel Balazki, Salih Benamara +28 more
2025CPT: Pharmacometrics & Systems Pharmacology1 citations Open access
Semantic Scholar
A quantification of gastric and duodenal fluid volumes in older adults using MRI.
Cleo Demeester, Matthias Van der Veken, J. Brouwers, R. Vanslembrouck +3 more
2024International journal of pharmaceutics1 citations Open access
Semantic Scholar
A new method for successful indirect bonding in relation to bond strength
Thomas Wendl, C. Bandl, W. Kern, B. Wendl +1 more
2022Biomedizinische Technik. Biomedical engineering1 citations
Semantic Scholar
Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug–Drug Interactions and Co-medication Regimens
D. Moj, N. Hanke, Hannah Britz, S. Frechen +4 more
2016AAPS Journal0 citations
Semantic Scholar
924: Prothrombin Complex Concentrate for Hemostasis Outside of Intracrainal Hemorrhage
A. Heine, A. Harding, Ke-Zhong Shen, K. Yoshikawa +16 more
20130 citations
Semantic Scholar
The role of Nodal-dependent transcription factors and blood vessels in the development of the zebrafish thyroid gland
K. Rohr, Burkhard Alt, Thomas Wendl, Dejan Adzic +1 more
20060 citations
Semantic Scholar

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