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B. Siesjö · SciRah

Researcher profile · Semantic Scholar

B. Siesjö

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B. Siesjö — researcher profile on SciRah

h-index: 115
Works: 589
Citations: 50K

Most-cited papers

Calcium in ischemic cell death.
T. Kristian, B. Siesjö
1998Stroke884 citations Open access
Semantic Scholar
The density and distribution of ischemic brain injury in the rat following 2–10 min of forebrain ischemia
M. L. Smith, R. Auer, B. Siesjö
2004Acta Neuropathologica443 citations
Semantic Scholar
Involvement of Caspase-3 in Cell Death after Hypoxia–Ischemia Declines during Brain Maturation
Bing-Ren Hu, Chunli Liu, Yi-Bing Ouyang, K. Blomgren +1 more
2000Journal of Cerebral Blood Flow and Metabolism356 citations Open access
Semantic Scholar
Reperfusion damage following focal ischemia: pathophysiology and therapeutic windows.
S. Kuroda, B. Siesjö
1997Clinical Neuroscience298 citations
Semantic Scholar
Survival- and Death-Promoting Events after Transient Cerebral Ischemia: Phosphorylation of Akt, Release of Cytochrome C, and Activation of Caspase-Like Proteases
Yi-Bing Ouyang, Ying Tan, M. Comb, Chunli Liu +3 more
1999Journal of Cerebral Blood Flow and Metabolism259 citations Open access
Semantic Scholar
Neuroprotective Effects of a Novel Nitrone, NXY-059, after Transient Focal Cerebral Ischemia in the Rat
S. Kuroda, Ryoichi Tsuchidate, Maj-Lis Smith, K. R. Maples +1 more
1999Journal of Cerebral Blood Flow and Metabolism248 citations Open access
Semantic Scholar
Ischemic penumbra in a model of reversible middle cerebral artery occlusion in the rat
H. Memezawa, Hiroaki Minamisawa, Maj-Lis Smith, B. Siesjö
2004Experimental Brain Research220 citations
Semantic Scholar
The distribution of hypoglycemic brain damage
R. Auer, T. Wieloch, Y. Olsson, B. Siesjö
2004Acta Neuropathologica212 citations
Semantic Scholar
Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat.
H. Uchino, E. Elmér, Keiko Uchino, Ping-An Li +3 more
1998Brain Research196 citations
Semantic Scholar
The temporal evolution of hypoglycemic brain damage
R. Auer, H. Kalimo, Y. Olsson, B. Siesjö
2004Acta Neuropathologica181 citations
Semantic Scholar
Hyperglycemia enhances extracellular glutamate accumulation in rats subjected to forebrain ischemia.
P.-A. Li, A. Shuaib, H. Miyashita, Q.-P. He +2 more
2000Stroke174 citations
Semantic Scholar
Protein Aggregation after Focal Brain Ischemia and Reperfusion
Bing-Ren Hu, S. Janelidze, M. Ginsberg, R. Busto +4 more
2001Journal of Cerebral Blood Flow and Metabolism171 citations
Semantic Scholar
Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition.
H. Uchino, R. Minamikawa-Tachino, T. Kristian, G. Perkins +3 more
2002Neurobiology of Disease165 citations Open access
Semantic Scholar
Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia.
T. Yoshimoto, B. Siesjö
1999Brain Research152 citations
Semantic Scholar
Magnetic resonance imaging shows delayed ischemic striatal neurodegeneration
M. Fujioka, T. Taoka, Y. Matsuo, K. Mishima +9 more
2003Annals of Neurology140 citations
Semantic Scholar
Role and mechanisms of secondary mitochondrial failure.
B. Siesjö, E. Elmér, S. Janelidze, M. Keep +3 more
1999Acta neurochirurgica. Supplement134 citations
Semantic Scholar
Role of hyperglycaemia-related acidosis in ischaemic brain damage.
Pastukhova Li, B. Siesjö
1997Acta Physiologica Scandinavica133 citations
Semantic Scholar
Characteristics of the Calcium‐Triggered Mitochondrial Permeability Transition in Nonsynaptic Brain Mitochondria
T. Kristian, J. Gertsch, T. Bates, B. Siesjö
2000Journal of Neurochemistry128 citations Open access
Semantic Scholar
Pathogenesis of hippocampal neuronal death after hypoxia-ischemia changes during brain development.
C.-L. Liu, B. Siesjö, B.-R. Hu
2004Neuroscience116 citations Open access
Semantic Scholar
Hypoglycemic brain injury
H. Kalimo, C. Agardh, Y. Olsson, B. Siesjö
2004Acta Neuropathologica112 citations
Semantic Scholar
Pathophysiology and treatment of focal cerebral ischemia. Part I: Pathophysiology. (1992).
B. Siesjö
2008Journal of Neurosurgery100 citations Open access
Semantic Scholar
Hyperglycemia and Focal Brain Ischemia
L. Gisselsson, Maj-Lis Smith, B. Siesjö
1999Journal of Cerebral Blood Flow and Metabolism100 citations Open access
Semantic Scholar
Acidosis Promotes the Permeability Transition in Energized Mitochondria: Implications for Reperfusion Injury
Tibor Kristia'n, Paolo Bernardi, B. Siesjö
2001Journal of Neurotrauma98 citations
Semantic Scholar
Hyperthermia aggravates and hypothermia ameliorates epileptic brain damage
J. Lundgren, Maj-Lis Smith, G. Blennow, B. Siesjö
2004Experimental Brain Research97 citations
Semantic Scholar
Is the Cell Death Pathway Triggered by the Mitochondrion or the Endoplasmic Reticulum?
B. Siesjö, Bing-Ren Hu, T. Kristian
1999Journal of Cerebral Blood Flow and Metabolism90 citations Open access
Semantic Scholar
Calcium metabolism of focal and penumbral tissues in rats subjected to transient middle cerebral artery occlusion
Tibor Kristia'n, Gunilla Gidö, S. Kuroda, A. Schütz +1 more
1998Experimental Brain Research88 citations
Semantic Scholar
Effect of transient focal ischemia on blood-brain barrier permeability in the rat: correlation to cell injury
S. Albayrak, Qi Zhao, B. Siesjö, Maj-Lis Smith
1997Acta Neuropathologica85 citations
Semantic Scholar
Production of hydroxyl free radical by brain tissues in hyperglycemic rats subjected to transient forebrain ischemia.
Ping-An Li, Guang-Jun Liu, Qing-Ping He, R. Floyd +1 more
1999Free Radical Biology & Medicine83 citations
Semantic Scholar
Cyclosporin A enhances survival, ameliorates brain damage, and prevents secondary mitochondrial dysfunction after a 30-minute period of transient cerebral ischemia.
Ping-An Li, T. Kristian, Qing-Ping He, B. Siesjö
2000Experimental Neurology79 citations
Semantic Scholar
Changes in the bioenergetic state of rat hippocampus during 2.5 min of ischemia, and prevention of cell damage by cyclosporin A in hyperglycemic subjects
J. Folbergrová, Ping-An Li, H. Uchino, Maj-Lis Smith +1 more
1997Experimental Brain Research78 citations
Semantic Scholar
Alterations of Akt1 (PKBalpha) and p70(S6K) in transient focal ischemia.
S. Janelidze, Bing-Ren Hu, P. Siesjö, B. Siesjö
2001Neurobiology of Disease72 citations Open access
Semantic Scholar
Cyclosporin A, but not FK506, prevents the downregulation of phosphorylated Akt after transient focal ischemia in the rat.
T. Yoshimoto, H. Uchino, Qing-Ping He, Ping-An Li +1 more
2001Brain Research62 citations
Semantic Scholar
The immunosuppressants cyclosporin A and FK506 equally ameliorate brain damage due to 30-min middle cerebral artery occlusion in hyperglycemic rats.
S. Kuroda, S. Janelidze, B. Siesjö
1999Brain Research61 citations
Semantic Scholar
Hyperglycemia-exaggerated ischemic brain damage following 30 min of middle cerebral artery occlusion is not due to capillary obstruction.
Ping-An Li, L. Gisselsson, J. Keuker, J. Vogel +3 more
1998Brain Research61 citations
Semantic Scholar
ADAMTS13 gene deletion enhances plasma high-mobility group box1 elevation and neuroinflammation in brain ischemia–reperfusion injury
M. Fujioka, T. Nakano, Kazuhide Hayakawa, K. Irie +13 more
2012Neurological Sciences54 citations Open access
Semantic Scholar
Pathogenesis of brain lesions caused by experimental epilepsy
A. Atillo, B. Söderfeldt, H. Kalimo, Y. Olsson +1 more
2004Acta Neuropathologica50 citations
Semantic Scholar
The temporal evolution of hypoglycemic brain damage
R. Auer, H. Kalimo, Y. Olsson, B. Siesjö
2004Acta Neuropathologica47 citations
Semantic Scholar
Activity of Mitochondrial Respiratory Chain Enzymes after Transient Focal Ischemia in the Rat
L. Canevari, S. Kuroda, T. Bates, J. Clark +1 more
1997Journal of Cerebral Blood Flow and Metabolism47 citations Open access
Semantic Scholar
The calmodulin antagonist trifluoperazine in transient focal brain ischemia in rats. Anti-ischemic effect and therapeutic window.
Satoshi Kuroda, A. Nakai, Tibor Kristia'n, B. Siesjö
1997Stroke44 citations
Semantic Scholar
Morphological lesions in the brain preceding the development of postischemic seizures
M. L. Smith, H. Kalimo, D. Warner, B. Siesjö
2004Acta Neuropathologica42 citations
Semantic Scholar
Early release of cytochrome C and activation of caspase-3 in hyperglycemic rats subjected to transient forebrain ischemia.
Ping-An Li, Qing-Ping He, Yi-Bing Ouyang, Chunli Liu +2 more
2001Brain Research42 citations
Semantic Scholar
Effects of streptozotocin-induced hyperglycemia on brain damage following transient ischemia.
Cai-xia Li, Ping-An Li, Qing-Ping He, Yi-Bing Ouyang +1 more
1998Neurobiology of Disease40 citations Open access
Semantic Scholar
Effect of NXY-059 on secondary mitochondrial dysfunction after transient focal ischemia; comparison with cyclosporin A.
T. Yoshimoto, T. Kristian, Bing-Ren Hu, Yi-Bing Ouyang +1 more
2002Brain Research39 citations
Semantic Scholar
NXY-059 maintains Akt activation and inhibits release of cytochrome C after focal cerebral ischemia.
T. Yoshimoto, Palanisamy Kanakaraj, Jing-Ying Ma, Mingshan Cheng +5 more
2002Brain Research38 citations
Semantic Scholar
Release of mitochondrial aspartate aminotransferase (mAST) following transient focal cerebral ischemia suggests the opening of a mitochondrial permeability transition pore
Yibing Ou-Yang, S. Kuroda, T. Kristian, B. Siesjö
199738 citations
Semantic Scholar
A mismatch between the abnormalities in diffusion- and susceptibility-weighted magnetic resonance imaging may represent an acute ischemic penumbra with misery perfusion.
M. Fujioka, K. Okuchi, Asami Iwamura, T. Taoka +1 more
2013Journal of Stroke & Cerebrovascular Diseases35 citations
Semantic Scholar
Phosphorylation of extracellular signal-regulated kinase after transient cerebral ischemia in hyperglycemic rats.
Ping-An Li, Qing-Ping He, Yi-Bing Ouyang, Bing-Ren Hu +1 more
2001Neurobiology of Disease34 citations Open access
Semantic Scholar
Hyperglycemia Enhances DNA Fragmentation after Transient Cerebral Ischemia
Ping-An Li, I. Rasquinha, Qing-Ping He, B. Siesjö +3 more
2001Journal of Cerebral Blood Flow and Metabolism32 citations
Semantic Scholar
Is Neuronal Injury Caused by Hypoglycemic Coma of the Necrotic or Apoptotic Type?
Yi-Bing Ouyang, Qing-Ping He, Ping-An Li, S. Janelidze +2 more
2000Neurochemical Research31 citations
Semantic Scholar
Hypothermia ameliorates ischemic brain damage and suppresses the release of extracellular amino acids in both normo- and hyperglycemic subjects.
Ping-An Li, Qing-Ping He, Hiroki Miyashita, Wendy Howllet +2 more
1999Experimental Neurology31 citations
Semantic Scholar

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Ping-An Li×12
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Ping-An Li — researcher profile on SciRah
T. Kristian×8
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T. Kristian — researcher profile on SciRah
Bing-Ren Hu×8
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Bing-Ren Hu — researcher profile on SciRah
Yi-Bing Ouyang×8
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Maj-Lis Smith — researcher profile on SciRah

Qing-Ping He×7

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S. Kuroda — researcher profile on SciRah

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H. Uchino — researcher profile on SciRah

S. Janelidze×5

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S. Janelidze — researcher profile on SciRah

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R. Auer — researcher profile on SciRah

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H. Kalimo — researcher profile on SciRah

T. Yoshimoto×4

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T. Yoshimoto — researcher profile on SciRah