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K. R. Maples · SciRah

Researcher profile · Semantic Scholar

K. R. Maples

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K. R. Maples — researcher profile on SciRah

h-index: 21
Works: 49
Citations: 1,834

Most-cited papers

Neuroprotective Effects of a Novel Nitrone, NXY-059, after Transient Focal Cerebral Ischemia in the Rat
S. Kuroda, Ryoichi Tsuchidate, Maj-Lis Smith, K. R. Maples +1 more
1999Journal of Cerebral Blood Flow and Metabolism248 citations Open access
Semantic Scholar
Free radical metabolite of uric acid.
K. R. Maples, Ronald P. Mason
1988Journal of Biological Chemistry214 citations
Semantic Scholar
Discovery and structure-activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis.
Tsutomu Akama, S. Baker, Yong-Kang Zhang, V. Hernández +6 more
2009Bioorganic & Medicinal Chemistry Letters190 citations Open access
Semantic Scholar
A comparison of the inflammatory response of the lung to inhaled versus instilled particles in F344 rats.
R. Henderson, K. Driscoll, J. Harkema, R. Lindenschmidt +3 more
1995Fundamental and Applied Toxicology155 citations
Semantic Scholar
Boron‐based phosphodiesterase inhibitors show novel binding of boron to PDE4 bimetal center
Y. Freund, Tsutomu Akama, M. R. K. Alley, Joana Antunes +11 more
2012FEBS Letters99 citations Open access
Semantic Scholar
NXY-059, a novel free radical trapping compound, reduces cortical infarction after permanent focal cerebral ischemia in the rat.
Zonghang Zhao, Mingshan Cheng, K. R. Maples, Jing-Ying Ma +1 more
2001Brain Research99 citations
Semantic Scholar
Amyloid β Peptides Do Not Form Peptide-derived Free Radicals Spontaneously, but Can Enhance Metal-catalyzed Oxidation of Hydroxylamines to Nitroxides*
S. Dikalov, M. Vitek, K. R. Maples, Ronald P. Mason
1999Journal of Biological Chemistry98 citations Open access
Semantic Scholar
A comparison of cobalt(II) and iron(II) hydroxyl and superoxide free radical formation.
M. Kadiiska, K. R. Maples, Ronald P. Mason
1989Archives of Biochemistry and Biophysics92 citations
Semantic Scholar
In vivo thiyl free radical formation from hemoglobin following administration of hydroperoxides.
K. R. Maples, C. Kennedy, S. Jordan, Ronald P. Mason
1990Archives of Biochemistry and Biophysics90 citations
Semantic Scholar
Identification of a novel boron-containing antibacterial agent (AN0128) with anti-inflammatory activity, for the potential treatment of cutaneous diseases.
S. Baker, Tsutomu Akama, Yong-Kang Zhang, V. Sauro +8 more
2006Bioorganic & Medicinal Chemistry Letters83 citations
Semantic Scholar
Comparison of the radical trapping ability of PBN, S-PBN and NXY-059
K. R. Maples, Fang Ma, Yong-Kang Zhang
2001Free radical research80 citations
Semantic Scholar
Aniline-, phenylhydroxylamine-, nitrosobenzene-, and nitrobenzene-induced hemoglobin thiyl free radical formation in vivo and in vitro.
K. R. Maples, P. Eyer, R. Mason
1990Molecular Pharmacology73 citations
Semantic Scholar
Translational Research Involving Oxidative Stress and Diseases of Aging
R. Floyd, R. Towner, T. He, K. Hensley +1 more
2011Free Radical Biology & Medicine66 citations Open access
Semantic Scholar
Fiber-induced hydroxyl radical formation: correlation with mesothelioma induction in rats and humans.
K. R. Maples, N. Johnson
1992Carcinogenesis49 citations
Semantic Scholar
In vivo rat hemoglobin thiyl free radical formation following phenylhydrazine administration.
K. R. Maples, S. Jordan, Ronald P. Mason
1988Molecular Pharmacology46 citations
Semantic Scholar
Glutathione release by pulmonary alveolar macrophages in response to particles in vitro.
Dea S. Boehme, K. R. Maples, R. F. Henderson
1992Toxicology Letters40 citations
Semantic Scholar
NXY-059 maintains Akt activation and inhibits release of cytochrome C after focal cerebral ischemia.
T. Yoshimoto, Palanisamy Kanakaraj, Jing-Ying Ma, Mingshan Cheng +5 more
2002Brain Research38 citations
Semantic Scholar
Particle clearance and histopathology in lungs of F344/N rats and B6C3F1 mice inhaling nickel oxide or nickel sulfate.
Janet M. Benson, I-Yiin Chang, Yung-Sung Cheng, F. F. Hahn +4 more
1995Fundamental and Applied Toxicology37 citations
Semantic Scholar
Nitrone-Related Therapeutics
K. R. Maples, A. Green, Robert A. Floyd
2004CNS Drugs34 citations
Semantic Scholar
Fate of Inhaled Nickel Oxide and Nickel Subsulfide in F344/N Rats
J. Benson, E. Barr, W. Bechtold, Yung-sung Cheng +5 more
199434 citations
Semantic Scholar
Particle Clearance and Histopathology in Lungs of F344/N Rats and B6C3F1 Mice Inhaling Nickel Oxide or Nickel Sulfate
J. Benson, I. Chang, Yung-sung Cheng, F. Hahn +4 more
199529 citations Open access
Semantic Scholar
The nitric oxide/heme protein complex as a biologic marker of exposure to nitrogen dioxide in humans, rats, and in vitro models.
K. R. Maples, T. Sandström, Yin-Fong Su, R. F. Henderson
1991American Journal of Respiratory Cell and Molecular Biology28 citations
Semantic Scholar
In vivo rat hemoglobin thiyl free radical formation following administration of phenylhydrazine and hydrazine-based drugs.
K. R. Maples, S. Jordan, Ronald P. Mason
1988Drug Metabolism And Disposition26 citations
Semantic Scholar
Levels of epoxides in blood during inhalation of alkenes and alkene oxides
K. R. Maples, A. Dahl
199324 citations
Semantic Scholar
Species differences in the metabolism of 1,3-butadiene in vivo.
R. Henderson, W. Bechtold, P. Sabourin, K. R. Maples +1 more
1993IARC scientific publications14 citations
Semantic Scholar
Polycyclic aromatic hydrocarbons decrease intracellular glutathione levels in the A20.1 murine B cell lymphoma.
Jane W. Yuan, J. A. Krieger, K. R. Maples, J. L. Born +1 more
1994Fundamental and Applied Toxicology13 citations
Semantic Scholar
Discovery and Structure—Activity Study of a Novel Benzoxaborole Antiinflammatory Agent (AN2728) for the Potential Topical Treatment of Psoriasis and Atopic Dermatitis.
Tsutomu Akama, S. Baker, Yong-Kang Zhang, V. Hernández +6 more
200912 citations
Semantic Scholar
In vivo detection of free radical metabolites
C. Kennedy, K. R. Maples, R. Mason
199012 citations Open access
Semantic Scholar
Effects of Cigarette Smoke on the Glutathione Status of the Upper and Lower Respiratory Tract of Rats
K. R. Maples, K. Nikula, Bean T. Chen, G. Finch +2 more
199311 citations
Semantic Scholar
Blood levels of propylene oxide during propylene inhalation and effect on hepatic and nasal cytochrome P-450 concentrations.
K. R. Maples, A. Dahl
1991Drug Metabolism And Disposition11 citations
Semantic Scholar
EPR study of radicals derived from 3-buten-2-ol and 1,3-butanediol
Peter G. Smith, K. R. Maples, Cathy C. Devlin, G. Mccrohan
198610 citations
Semantic Scholar
On the mechanism of the inhibition of glutamine synthetase and creatine phosphokinase by methionine sulfoxide
A. Haghighi, K. R. Maples
1996Journal of Neuroscience Research9 citations
Semantic Scholar
EPR study of the oxidation of phenylhydrazine initiated by the e titanous chloride/hydrogen peroxide reaction and by oxyhemoglobin
Peter G. Smith, K. R. Maples
19859 citations
Semantic Scholar
An efficient method for synthesizing [d6]‐butadiene monoepoxide
K. R. Maples, J. Lane, A. Dahl
19928 citations
Semantic Scholar
EPR study of radicals derived from five-carbon alkenenitriles
Peter G. Smith, K. R. Maples, Reuben Diaz
19866 citations
Semantic Scholar
Fiber-Induced Hydroxyl Radical Formation and DNA Damage
N. Johnson, K. R. Maples
19944 citations
Semantic Scholar
Synthesis and EPR Evaluation of the Nitrone PBN-[tert-13C] for Spin Trapping Competition
Yong-Kang Zhang, K. R. Maples
20022 citations
Semantic Scholar
Electron paramagnetic resonance study of the reactions of the spin trap 2,4,6-tribromonitrosobenzene in benzene solutions
Peter G. Smith, K. R. Maples, R. Lau
19922 citations Open access
Semantic Scholar
In vivo detection of free radical metabolites by spin trapping
M. Symons, R. Mason, K. R. Maples, K. Knecht
19892 citations
Semantic Scholar
In vivo Detection of free radical metabolites of toxic chemicals and drugs in biological fluids
R. Mason, K. R. Maples, C. Kennedy, K. Knecht
19901 citations
Semantic Scholar
Small molecules containing boron as antiinflammatory agents
S. Baker, Virginia Sanders, Tsutomu Akama, C. Bellinger-Kawahara +6 more
20070 citations
Semantic Scholar
SMALL boron MOLECULES AS ANTI-INFLAMMATORY AGENTS
S. Baker, Virginia Sanders, C. Bellinger-Kawahara, Y. Freund +6 more
20070 citations
Semantic Scholar
Halogen-substituted boronophthalider for the treatment of infections
S. Baker, Tsutomu Akama, C. Bellinger-Kawahara, V. Hernández +6 more
20060 citations
Semantic Scholar
Boronoftalidas halogen substituted for treating infections
S. Baker, Tsutomu Akama, C. Bellinger-Kawahara, V. Hernández +7 more
20060 citations
Semantic Scholar
Boronophthalides substitues par halogene pour le traitement d'infections
S. Baker, Tsutomu Akama, C. Bellinger-Kawahara, V. Hernández +7 more
20060 citations
Semantic Scholar
Biocides compounds boronoftalida
S. Baker, Tsutomu Akama, C. Bellinger-Kawahara, V. Hernández +6 more
20060 citations
Semantic Scholar
Treatment or prevention of skin or tissue states in animals using of boryloxypyridylmethanonen
D. Perry, K. R. Maples, C. Bellinger-Kawahara
20050 citations
Semantic Scholar
Pharmaceutical Development of a New Class of Antibiotics Effective Against Anthrax
K. R. Maples
20040 citations
Semantic Scholar
NXY-059, a novel free radical trapping agent, reduces cortical infarction after permanent focal ischaemia in rats
Mingshan Cheng, Zonghang Zhao, J. Ma, K. R. Maples +1 more
20000 citations
Semantic Scholar
NXY-059: Neuroprotective effects in a rat focal stroke model
K. R. Maples, S. Kuroda, Ryoichi Tsuchidate, Maj-Lis Smith +1 more
19990 citations
Semantic Scholar

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