Researcher profile · Semantic Scholar

Q. McAfee

h-index: 15
Works: 33
Citations: 2,428

Most-cited papers

A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme
M. Rosenfeld, Xiao-Bu Ye, J. Supko, S. Desideri +16 more
2014Autophagy497 citations Open access
Semantic Scholar
Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma.
Xiao-Hong Ma, S. Piao, S. Dey, Q. McAfee +17 more
2014Journal of Clinical Investigation430 citations Open access
Semantic Scholar
Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency
Q. McAfee, Zhihui Zhang, A. Samanta, Samuel M Levi +8 more
2012Proceedings of the National Academy of Sciences of the United States of America412 citations Open access
Semantic Scholar
Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma
Xiao-Hong Ma, S. Piao, Dan Wang, Q. McAfee +4 more
2011Clinical Cancer Research241 citations Open access
Semantic Scholar
PPT1 promotes tumor growth and is the molecular target of chloroquine derivatives in cancer.
Vito W. Rebecca, Michael C. Nicastri, C. Fennelly, Cynthia I Chude +20 more
2018Cancer Discovery211 citations Open access
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A unified approach to targeting the lysosome’s degradative and growth signaling roles
Vito W. Rebecca, Michael C. Nicastri, N. McLaughlin, C. Fennelly +28 more
2017Cancer Discovery193 citations Open access
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Genetic and phenotypic landscape of peripartum cardiomyopathy
Rahul Goli, Jian Li, J. Brandimarto, L. Levine +27 more
2021Circulation137 citations Open access
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Truncated titin proteins in dilated cardiomyopathy
Q. McAfee, C. Y. Chen, Yi-Fan Yang, M. Caporizzo +11 more
2021Science Translational Medicine68 citations Open access
Semantic Scholar
Four peptides decrease the number of human pancreatic adenocarcinoma cells
B. Vesely, Q. McAfee, William R. Jr Gower, D. Vesely
2003European Journal of Clinical Investigation61 citations
Semantic Scholar
Novel therapeutic approach for cancer using four cardiovascular hormones
D. Vesely, Linda C. Clark, A. Garces, Q. McAfee +2 more
2004European Journal of Clinical Investigation46 citations
Semantic Scholar
ALDH1A1 and HLTF modulate the activity of lysosomal autophagy inhibitors in cancer cells
S. Piao, R. Ojha, Vito W. Rebecca, A. Samanta +8 more
2017Autophagy31 citations Open access
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Gastric atrial natriuretic peptide regulates endocrine secretion in antrum and fundus of human and rat stomach.
William R. Gower, S. Premaratne, R. McCuen, A. Arimura +2 more
2003American Journal of Physiology - Gastrointestinal and Liver Physiology31 citations
Semantic Scholar
Identification, regulation and anti-proliferative role of the NPR-C receptor in gastric epithelial cells
William R. Jr Gower, G. Carter, Q. McAfee, Suzanne M. Solivan
2006Molecular and Cellular Biochemistry21 citations
Semantic Scholar
Extracellular stiffness induces contractile dysfunction in adult cardiomyocytes via cell-autonomous and microtubule-dependent mechanisms
A. Vite, M. Caporizzo, Elise A. Corbin, J. Brandimarto +4 more
2022Basic Research in Cardiology20 citations Open access
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Truncated titin protein in dilated cardiomyopathy incorporates into the sarcomere and transmits force
Q. McAfee, M. Caporizzo, K. Uchida, K. Bedi +3 more
2023Journal of Clinical Investigation16 citations Open access
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Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer
Yuri Kim, Seongwon Kim, David Saul, Meraj Neyazi +28 more
2024Journal of Clinical Investigation7 citations Open access
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Autophagy Inhibition as a Strategy for Cancer Therapy
Xiao-Hong Ma, S. Piao, Q. McAfee, R. Amaravadi
20164 citations
Semantic Scholar
Digital Light Processing 3D Printing Enables Versatile Fabrication of Human Engineered Heart Tissues
Abhishek P. Dhand, Miranda A. Juarros, Thomas G. Martin, Manuela Garay-Sarmiento +13 more
2026Cell biomaterials3 citations Open access
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Prediction and validation of host cleavage targets of SARS-CoV-2 3C-like protease
Nora Yucel, S. Marchianò, Evan Tchelepi, G. Paterlini +6 more
2022bioRxiv3 citations Open access
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Digital Light Processing 3D Printing enables High Throughput Fabrication of Human Engineered Heart Tissues for Disease Modeling
Abhishek P. Dhand, Miranda A. Juarros, Thomas G. Martin, Gabriel J. Rodriguez-Rivera +11 more
2024bioRxiv2 citations
Semantic Scholar
Unbiased cleavage site prediction uncovers viral antagonism of host innate immunity by SARS-CoV-2 3C-like protease
Nora Yucel, S. Marchiano, Evan Tchelepi, G. Paterlini +10 more
2026JCI Insight0 citations Open access
Semantic Scholar
A-band truncated titin transmits force from the Z-disc to the M-line in human dilated cardiomyopathy myocardium
Q. McAfee, M. Caporizzo, K. Uchida, K. Bedi +3 more
2024Biophysical Journal0 citations
Semantic Scholar
Truncated titin protein in dilated cardiomyopathy
Q. McAfee, Christina Yingxian Chen, Yi-Fan Yang, M. Caporizzo +11 more
2022Biophysical Journal0 citations Open access
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Truncated titin in the cardiac myofibril in dilated cardiomyopathy
Q. McAfee, C. Y. Chen, Yi-Fan Yang, M. Caporizzo +11 more
2022Journal of Molecular and Cellular Cardiology0 citations
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Abstract P494: Truncated Titin Protein In Dilated Cardiomyopathy
Q. McAfee, C. Y. Chen, M. Caporizzo, M. Morley +10 more
2021Circulation Research0 citations
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Abstract 112: The 3CL Protease Of SARS-CoV2 Induces Sarcomeric Degradation Through Cleavage Of The Giant Protein Obscurin
Nora Yucel, Q. McAfee, M. Paterlini, Z. Arany
2021Circulation Research0 citations
Semantic Scholar
Abstract 335: Titin Truncations in Human Heart Tissue
Q. McAfee, J. Brandimarto, Joshua Rhoades, Ken Bede +2 more
2019Circulation Research0 citations
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stomachin antrum and fundus of human and rat Gastric atrial natriuretic peptide regulates endocrine
William R. Jr Gower, S. Premaratne, R. McCuen, A. Arimura +1 more
20160 citations
Semantic Scholar
Abstract 1024: Expression pattern of ALDH1A1 and HLTF predicts sensitivity to lysosomal autophagy inhibitors in cancer cells
S. Piao, A. Samanta, Xiao-Hong Ma, Q. McAfee +5 more
20160 citations
Semantic Scholar
Abstract 1018: Structural features of novel dimeric quinacrines that have single-agent antitumor activity determine the mechanism of action: destabilization of mTORC1/lysosomal interaction versus DNA damage
Vito W. Rebecca, Michael C. Nicastri, Noel McGlaughlin, Q. McAfee +11 more
20160 citations
Semantic Scholar
Abstract 1679A: HLTF gene silencing predicts sensitivity to lysosomal autophagy inhibitors in cancer cells.
S. Piao, A. Samanta, Xiao-Hong Ma, Q. McAfee +4 more
20130 citations
Semantic Scholar
Proliferative effects of ANP on pancreatic cancer cells are mediated by natriuretic peptide receptor subtypes A and C
William R. Jr Gower, S. Solivan, Q. McAfee
20030 citations
Semantic Scholar
Localization and expression of natriuretic peptide receptor subtype A and subtype C in rat parietal cells
William R. Jr Gower, S. Premaratne, Q. McAfee, P. Fabri +3 more
20000 citations
Semantic Scholar

Xiao-Hong Ma

×7

J. Brandimarto×7

M. Caporizzo×7

J. Winkler×6

K. Bedi×6

Vito W. Rebecca×5

T. Cappola×5

Benjamin L. Prosser×5