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D. Machover · SciRah

Researcher profile · Semantic Scholar

D. Machover

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D. Machover — researcher profile on SciRah

h-index: 20
Works: 94
Citations: 2,480

Most-cited papers

Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. Advanced Colorectal Cancer Meta-Analysis Project.
P. Piedbois, Marc Buyse, Y. Rustum, D. Machover +6 more
1992Journal of Clinical Oncology1,205 citations
Semantic Scholar
A review of the evolution of systemic chemotherapy in the management of colorectal cancer.
B. Gustavsson, G. Carlsson, D. Machover, N. Petrelli +4 more
2015Clinical colorectal cancer497 citations Open access
Semantic Scholar
Two consecutive phase II studies of oxaliplatin (L-OHP) for treatment of patients with advanced colorectal carcinoma who were resistant to previous treatment with fluoropyrimidines.
D. Machover, E. Díaz-Rubio, A. de Gramont, A. Schilf +13 more
1996Annals of Oncology413 citations Open access
Semantic Scholar
Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid.
D. Machover, E. Goldschmidt, P. Chollet, G. Metzger +6 more
1986Journal of Clinical Oncology368 citations
Semantic Scholar
Hepatic resection after rescue cetuximab treatment for colorectal liver metastases previously refractory to conventional systemic therapy.
R. Adam, T. Aloia, F. Lévi, D. Wicherts +9 more
2007Journal of Clinical Oncology211 citations
Semantic Scholar
Extramedullary relapse in acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy
S. de Botton, M. A. Sanz, S. Chevret, H. Dombret +18 more
2006Leukemia161 citations Open access
Semantic Scholar
A comprehensive review of 5‐fluorouracil and leucovorin in patients with metastatic colorectal carcinoma
D. Machover
1997Cancer142 citations Open access
Semantic Scholar
Establishment and characterization of a new human eosinophilic leukemia cell line.
H. Saito, A. Bourinbaiar, M. Ginsburg, K. Minato +5 more
1985Blood138 citations Open access
Semantic Scholar
Treatment of advanced colorectal and gastric adenocarcinomas with 5-FU combined with high-dose folinic acid: a pilot study.
D. Machover, L. Schwarzenberg, E. Goldschmidt, J. Tourani +7 more
1982Cancer treatment reports137 citations
Semantic Scholar
Leukaemic presentation of small cell variant anaplastic large cell lymphoma: report of four cases
C. Bayle, A. Charpentier, E. Duchayne, A. Manel +10 more
1999British Journal of Haematology80 citations Open access
Semantic Scholar
Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid.
D. Machover, E. Goldschmidt, P. Chollet, G. Metzger +6 more
1987NCI monographs : a publication of the National Cancer Institute68 citations
Semantic Scholar
Rescue chemotherapy using multidrug chronomodulated hepatic arterial infusion for patients with heavily pretreated metastatic colorectal cancer
M. Bouchahda, R. Adam, S. Giacchetti, D. Castaing +6 more
2009Cancer57 citations Open access
Semantic Scholar
Fluorouracil combined with the pure (6S)-stereoisomer of folinic acid in high doses for treatment of patients with advanced colorectal carcinoma: a phase I-II study.
D. Machover, Xavier Grison, E. Goldschmidt, J. Zittoun +11 more
1992Journal of the National Cancer Institute46 citations
Semantic Scholar
Dexamethasone, high-dose cytarabine, and oxaliplatin (DHAOx) as salvage treatment for patients with initially refractory or relapsed non-Hodgkin's lymphoma.
D. Machover, Béatrice Delmas-Marsalet, S. Misra, Y. Gumus +12 more
2001Annals of Oncology45 citations Open access
Semantic Scholar
Phase I-II study of two consecutive courses of high-dose epipodophyllotoxin, ifosfamide, and carboplatin with autologous bone marrow transplantation for treatment of adult patients with solid tumors.
J. Lotz, D. Machover, B. Malassagne, B. Hingh +6 more
1991Journal of Clinical Oncology43 citations
Semantic Scholar
Bone marrow stromal cell defects and 1 alpha,25-dihydroxyvitamin D3 deficiency underlying human myeloid leukemias.
I. Blazsek, C. Farabos, P. Quittet, M. Labat +5 more
1996Cancer Detection and Prevention42 citations
Semantic Scholar
Phase 1/2a study of EKB-569, an irreversible inhibitor of epidermal growth factor receptor, in combination with 5-fluorouracil, leucovorin, and oxaliplatin (FOLFOX-4) in patients with advanced colorectal cancer (CRC).
S. Tejpar, E. Van Cutsem, E. Gamelin, D. Machover +6 more
2004Journal of Clinical Oncology31 citations
Semantic Scholar
Acute renal failure related to oxaliplatin-induced intravascular hemolysis
A. Ulusakarya, S. Misra, M. Haydar, H. Habert +4 more
2010Medical Oncology29 citations
Semantic Scholar
Large scale recovery and characterization of stromal cell-associated primitive haemopoietic progenitor cells from filter-retained human bone marrow
I. Blazsek, B. D. Marsalet, S. Legras, S. Marion +2 more
1999Bone Marrow Transplantation24 citations Open access
Semantic Scholar
Effects in Cancer Cells of the Recombinant l-Methionine Gamma-Lyase from Brevibacterium aurantiacum. Encapsulation in Human Erythrocytes for Sustained l-Methionine Elimination
D. Machover, L. Rossi, J. Hamelin, C. Desterke +13 more
2019Journal of Pharmacology and Experimental Therapeutics23 citations Open access
Semantic Scholar
Phase II trial with D‐Trp‐6‐LH‐RH in prostatic carcinoma: Comparison with other hormonal agents
G. Mathé, L. Schwarzenberg, M. Vovan, D. Machover +16 more
1986The Prostate23 citations
Semantic Scholar
Treatment of cancer cells with methioninase produces DNA hypomethylation and increases DNA synthesis.
D. Machover, J. Zittoun, R. Saffroy, P. Broët +14 more
2002Cancer Research22 citations
Semantic Scholar
Effectiveness of Mouse Interferon α/β Compared to Single-Agent Chemotherapy in Increasing Survival Time of Mice After Intravenous Inoculation of Friend Erythroleukemial Cells
I. Gresser, C. Maury, F. Belardelli, M. Maunoury +1 more
198822 citations
Semantic Scholar
Prevention of pathologies associated with oxidative stress and dietary intake deficiencies: folate deficiency and requirements.
H. Tapiero, K. D. Tew, Laurent Gaté, D. Machover
2001Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie21 citations
Semantic Scholar
Novel somatic mutations of the VHL gene in an erythropoietin‐producing renal carcinoma associated with secondary polycythemia and elevated circulating endothelial progenitor cells
F. H. Rad, A. Ulusakarya, S. Gad, M. Sibony +4 more
2008American journal of hematology/oncology20 citations
Semantic Scholar
Treatment of lymphoid neoplasias with interferon. I. Human fibroblastic beta-interferon in malignant gammapathies. Phase II trial.
J. Misset, G. Mathé, J. Gastiaburu, A. Goutner +9 more
1982Anticancer Research17 citations
Semantic Scholar
Feasibility of cetuximab given with a simplified schedule every 2 weeks in advanced colorectal cancer: a multicenter, retrospective analysis
M. Bouchahda, T. Macarulla, G. LIedo, F. Lévi +12 more
2011Medical Oncology16 citations
Semantic Scholar
Symptoms in cancer patients and an unusual tumor: Case 1. Regression of hypertrophic pulmonary osteoarthropathy following chemotherapy for lung metastases of a nasopharyngeal carcinoma.
A. Ulusakarya, Y. Gumus, N. Brahimi, B. Delmas-Marsalet +5 more
2005Journal of Clinical Oncology15 citations Open access
Semantic Scholar
Phase II trial of D-Trp-6-LH-RH in advanced breast cancer
G. Mathé, R. Kelling, M. Vovan, J. Gastiaburu +8 more
198615 citations
Semantic Scholar
Phase I-II study of aclarubicin for treatment of acute myeloid leukemia.
D. Machover, J. Gastiaburu, M. Delgado, E. Goldschmidt +6 more
1984Cancer treatment reports14 citations
Semantic Scholar
Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil combined with high-dose folinic acid. An update.
D. Machover, E. Goldschmidt, L. Schwarzenberg, J. Vandenbulcke +3 more
1985Chemioterapia : international journal of the Mediterranean Society of Chemotherapy13 citations
Semantic Scholar
[Treatment of leukemias and lymphomas by interferons: II. Phase II of the trial treatment of chronic lymphoid leukemia by human interferon alpha+].
J. Misset, G. Mathé, J. Gastiaburu, A. Goutner +6 more
1982Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie12 citations
Semantic Scholar
Treatment of lymphoid neoplasias with interferon. II. Human leucocyte alpha-interferon in chronic lymphatic leukemia (CLL). PHase I-II trial.
J. Misset, G. Mathé, J. Gastiaburu, A. Goutner +8 more
1982Anticancer Research11 citations
Semantic Scholar
Treatment of acute myeloid leukemia with a combination of intensive induction chemotherapy, early consolidation, splenectomy and long‐term maintenance chemotherapy
D. Machover, H. Rappaport, L. Schwarzenberg, J. Misset +7 more
1984Cancer9 citations
Semantic Scholar
Pharmacologic modulation of 5-fluorouracil by folinic acid and high-dose pyridoxine for treatment of patients with digestive tract carcinomas
D. Machover, W. Almohamad, V. Castagné, C. Desterke +4 more
2021Scientific Reports8 citations Open access
Semantic Scholar
Enhancement of 5-Fluorouracil Cytotoxicity by Pyridoxal 5′-Phosphate and Folinic Acid in Tandem
D. Machover, E. Goldschmidt, R. Mollicone, Farhad Haghighi-Rad +5 more
2018Journal of Pharmacology and Experimental Therapeutics8 citations Open access
Semantic Scholar
Excess of lympho-reticular cell complexes in the bone marrow linked to T cell mediated dysmyelopoiesis.
I. Blazsek, E. Goldschmidt, D. Machover, J. Misset +6 more
1986Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie8 citations
Semantic Scholar
Treatment with rituximab, dexamethasone, high-dose cytarabine, and oxaliplatin (R-DHAOx) produces a strong long-term antitumor effect in previously treated patients with follicular non-Hodgkin's lymphoma.
D. Machover, B. Delmas-Marsalet, S. Misra, A. Ulusakarya +9 more
2010Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie7 citations
Semantic Scholar
Association of a POEMS syndrome and light chain deposit disease: first case report.
O. Lambotte, Antoine Durrbach, M. Ammor, Valérie Paradis +3 more
2001Clinical Nephrology7 citations
Semantic Scholar
A Computational Model for the PLP-Dependent Enzyme Methionine γ-Lyase
Xingyu Chen, P. Briozzo, D. Machover, T. Simonson
2022Frontiers in Molecular Biosciences6 citations Open access
Semantic Scholar
Phase-II trial with vindesine for regression induction in patients with leukemias and hematosarcomas
M. Bayssas, J. Gouveia, P. Ribaud, M. Musset +10 more
2004Cancer Chemotherapy and Pharmacology6 citations
Semantic Scholar
Tandem high-dose (HD) chemotherapy (CT) with VM-26, ifosfamide (IFM), and carboplatin (CBDCA) with autologous bone marrow transplantation (ABMT) for patients with stage IIIC-IV ovarian cancer (OC)
J. Lotz, D. Machover, A. Bellaiche, C. Bouleuc +2 more
19936 citations
Semantic Scholar
5-Fluorourcil combined with the [6S]-stereoisomer of folinic acid in high doses for treatment of patients with advanced colorectal carcinoma A phase I-II study of two consecutive regiments
D. Machover, X. Grison, E. Goldschmidt, J. Zittoun +13 more
19936 citations Open access
Semantic Scholar
An oriented phase-II trial ofd-Trp6-LH-RH in patients with prostatic carcinoma
G. Mathé, M. Vovan, J. Duchier, J. Misset +13 more
1984Medical Oncology and Tumor Pharmacotherapy6 citations
Semantic Scholar
Phase II trial of aclacinomycin in acute leukemia and lymphosarcoma.
G. Mathé, M. Gil, M. Delgado, M. Bayssas +8 more
1980Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer6 citations
Semantic Scholar
Pharmacologic modulation of 5-fluorouracil by folinic acid and pyridoxine for treatment of patients with advanced breast carcinoma
D. Machover, E. Goldschmidt, W. Almohamad, V. Castagné +5 more
2022Scientific Reports5 citations Open access
Semantic Scholar
738 Oxaliplatin (L-OHP®): Summary of results in advanced colorectal cancer (ACC)
F. Lévi, D. Machover, M. Marty, E. Díaz-Rubio +7 more
19955 citations
Semantic Scholar
Phase I-II study of aclacinomycin for a treatment of acute myeloid leukemia.
D. Machover, J. Gastiaburu, M. Delgado, E. Goldschmidt +6 more
1984Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie5 citations
Semantic Scholar
Effective salvage therapy of liver-only colorectal cancer metastases with chronomodulated irinotecan-fluorouracil-oxaliplatin via hepatic artery infusion.
M. Bouchahda, Rosalyn M. Adam, S. Giacchetti, Xiao-Mei Li +6 more
2006Journal of Clinical Oncology4 citations
Semantic Scholar
5-Fluorouracil combined with the [6S]-stereoisomer of folinic acid in high doses for treatment of patients with advanced colorectal carcinoma. A phase I-II study of two consecutive regimens.
D. Machover, X. Grison, E. Goldschmidt, J. Zittoun +6 more
1993Annals of Oncology4 citations
Semantic Scholar

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E. Goldschmidt×20
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E. Goldschmidt — researcher profile on SciRah
J. Misset×13
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J. Misset — researcher profile on SciRah
L. Schwarzenberg×13
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L. Schwarzenberg — researcher profile on SciRah
G. Mathé×13
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G. Mathé — researcher profile on SciRah

×8

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C. Jasmin — researcher profile on SciRah

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F. de Vassal×8

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J. Gastiaburu×7

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A. Ulusakarya×6

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J. Zittoun — researcher profile on SciRah