L. Rossi

Most-cited papers

Cell-based drug delivery.
F. Pierigé, Sonja Serafini, L. Rossi, M. Magnani
2008Advanced Drug Delivery Reviews296 citations
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Erythrocyte engineering for drug delivery and targeting
M. Magnani, L. Rossi, M. D'Ascenzo, I. Panzani +2 more
1998Biotechnology and applied biochemistry138 citations
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Drug delivery by red blood cells
S. Biagiotti, M. Paoletti, A. Fraternale, L. Rossi +1 more
2011IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology113 citations Open access
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Erythrocyte-mediated delivery of drugs, peptides and modified oligonucleotides
M. Magnani, L. Rossi, A. Fraternale, M. Bianchi +3 more
2002Gene Therapy103 citations Open access
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Low doses of dexamethasone constantly delivered by autologous erythrocytes slow the progression of lung disease in cystic fibrosis patients.
L. Rossi, M. Castro, F. D'Orio, G. Damonte +9 more
2004Blood Cells, Molecules & Diseases94 citations
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Erythrocyte‐mediated delivery of dexamethasone in patients with chronic obstructive pulmonary disease
L. Rossi, Sonja Serafini, Luigi Cenerini, Francesco Picardi +3 more
2001Biotechnology and applied biochemistry91 citations
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Observation of erythrocyte dynamics in the retinal capillaries and choriocapillaris using ICG-loaded erythrocyte ghost cells.
R. Flower, E. Peiretti, M. Magnani, L. Rossi +3 more
2008Investigative Ophthalmology and Visual Science69 citations Open access
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Erythrocyte-Mediated Delivery of Dexamethasone in Patients With Mild-to-Moderate Ulcerative Colitis, Refractory to Mesalamine: A Randomized, Controlled Study
F. Bossa, A. Latiano, L. Rossi, M. Magnani +7 more
2008American Journal of Gastroenterology68 citations
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Approaches to erythrocyte-mediated drug delivery
M. Magnani, L. Rossi
2014Expert Opinion on Drug Delivery64 citations
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Improved cellular uptake of functionalized single-walled carbon nanotubes
A. Antonelli, Sonja Serafini, M. Menotta, C. Sfara +5 more
2010Nanotechnology60 citations
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Long-term Treatment With Autologous Red Blood Cells Loaded With Dexamethasone 21–Phosphate in Pediatric Patients Affected by Steroid-dependent Crohn Disease
M. Castro, L. Rossi, B. Papadatou, F. Bracci +8 more
2007Journal of Pediatric Gastroenterology and Nutrition - JPGN60 citations Open access
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Engineering erythrocytes for the modulation of drugs' and contrasting agents' pharmacokinetics and biodistribution.
L. Rossi, F. Pierigé, A. Antonelli, Noemi Bigini +3 more
2016Advanced Drug Delivery Reviews57 citations Open access
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Macrophage Depletion by Free Bisphosphonates and Zoledronate-Loaded Red Blood Cells
R. Sabatino, A. Antonelli, S. Battistelli, R. Schwendener +2 more
2014PLoS ONE51 citations Open access
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Inhibition of Murine AIDS by Reduced Glutathione
A. Palamara, Enrico Garaci, G. Rotilio, M. Ciriolo +6 more
1996AIDS Research and Human Retroviruses51 citations
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Modulated red blood cell survival by membrane protein clustering
L. Chiarantini, L. Rossi, A. Fraternale, M. Magnani
1995Molecular and Cellular Biochemistry51 citations
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Red Blood Cell Membrane Processing for Biomedical Applications
L. Rossi, A. Fraternale, M. Bianchi, M. Magnani
2019Frontiers in Physiology50 citations Open access
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Erythrocyte-mediated delivery of phenylalanine ammonia lyase for the treatment of phenylketonuria in BTBR-Pah(enu2) mice.
L. Rossi, F. Pierigé, C. Carducci, Claudia Gabucci +6 more
2014Journal of Controlled Release48 citations Open access
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Red blood cells as an antigen‐delivery system
M. Magnani, L. Chiarantini, E. Vittoria, U. Mancini +2 more
1992Biotechnology and applied biochemistry46 citations
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Reengineering red blood cells for cellular therapeutics and diagnostics.
F. Pierigé, Noemi Bigini, L. Rossi, M. Magnani
2017Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology44 citations Open access
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Immunophilin-loaded erythrocytes as a new delivery strategy for immunosuppressive drugs.
S. Biagiotti, L. Rossi, M. Bianchi, E. Giacomini +4 more
2011Journal of Controlled Release44 citations
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New Synthetic Glutathione Derivatives with Increased Antiviral Activities
A. Palamara, G. Brandi, L. Rossi, E. Millo +5 more
2004Antiviral Chemistry & Chemotherapy44 citations Open access
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Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus.
L. Rossi, Sonja Serafini, L. Cappellacci, E. Balestra +6 more
2001Journal of Antimicrobial Chemotherapy44 citations Open access
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Ongoing Developments and Clinical Progress in Drug-Loaded Red Blood Cell Technologies
L. Rossi, F. Pierigé, Mattia Paolo Aliano, M. Magnani
2020BioDrugs42 citations Open access
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Erythrocytes as a novel delivery vehicle for biologics: from enzymes to nucleic acid-based therapeutics.
M. Magnani, F. Pierigé, L. Rossi
2012Therapeutic delivery42 citations
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Methanol detoxification by enzyme‐loaded erythrocytes
Mauro Magnani, A. Fazi, F. Mangani, L. Rossi +1 more
1993Biotechnology and applied biochemistry42 citations
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Dexamethasone improves redox state in ataxia telangiectasia cells by promoting an NRF2‐mediated antioxidant response
S. Biagiotti, M. Menotta, Sara Orazi, C. Spapperi +6 more
2016The FEBS Journal41 citations Open access
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Encapsulation, metabolism and release of 2-fluoro-ara-AMP from human erythrocytes.
A. Fraternale, L. Rossi, M. Magnani
1996Biochimica et Biophysica Acta39 citations
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Ex vivo encapsulation of dexamethasone sodium phosphate into human autologous erythrocytes using fully automated biomedical equipment.
G. Mambrini, M. Mandolini, L. Rossi, F. Pierigé +5 more
2017International journal of pharmaceutics38 citations Open access
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Feline Immunodeficiency Virus Infection of Macrophages: In Vitro and in Vivo Inhibition by Dideoxycytidine-5′-triphosphate-Loaded Erythrocytes
M. Magnani, L. Rossi, A. Fraternale, Lucia Silvotti +5 more
1994AIDS Research and Human Retroviruses38 citations
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Heterodimer-Loaded Erythrocytes as Bioreactors for Slow Delivery of the Antiviral Drug Azidothymidine and the Antimycobacterial Drug Ethambutol
L. Rossi, Giorgio Brandi, G. Schiavano, S. Scarfì +5 more
1999AIDS Research and Human Retroviruses36 citations
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Extracellular Vesicles as New Players in Drug Delivery: A Focus on Red Blood Cells-Derived EVs
S. Biagiotti, Faiza Abbas, Mariele Montanari, C. Barattini +4 more
2023Pharmaceutics34 citations Open access
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Erythrocytes-mediated Delivery of Dexamethasone 21-phosphate in Steroid-dependent Ulcerative Colitis: A Randomized, Double-blind Sham-controlled Study
F. Bossa, V. Annese, M. Valvano, A. Latiano +8 more
2013Inflammatory Bowel Diseases33 citations
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Macrophage Protection Against Human Immunodeficiency Virus or Herpes Simplex Virus by Red Blood Cell-Mediated Delivery of a Heterodinucleotide of Azidothymidine and Acyclovir
L. Rossi, Giorgio Brandi, G. Schiavano, E. Balestra +8 more
1998AIDS Research and Human Retroviruses33 citations
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Macrophage depletion induced by clodronate-loaded erythrocytes
L. Rossi, Sonja Serafini, A. Antonelli, F. Pierigé +7 more
2005Journal of drug targeting (Print)31 citations Open access
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High throughput HPLC-ESI-MS method for the quantitation of dexamethasone in blood plasma.
G. Damonte, A. Salis, L. Rossi, M. Magnani +1 more
2007Journal of Pharmaceutical and Biomedical Analysis29 citations
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Erythrocytes as carriers of reduced glutathione (GSH) in the treatment of retroviral infections.
Alessandra Fraternale, A. Casabianca, L. Rossi, L. Chiarantini +4 more
2003Journal of Antimicrobial Chemotherapy28 citations Open access
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Metabolism, mitochondrial uptake and toxicity of 2', 3'-dideoxycytidine.
L. Rossi, Sonja Serafini, G. Schiavano, A. Casabianca +3 more
1999Biochemical Journal28 citations Open access
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Drug Delivery through Phagocytosis of Red Blood Cells
Sonja Serafini, L. Rossi, A. Antonelli, A. Fraternale +5 more
2004Transfusion Medicine and Hemotherapy26 citations
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Azidothymidine homodinucleotide-loaded erythrocytes and bioreactors for slow delivery of the antiretroviral drug azidothymidine.
Umberto Benatti, M. Giovine, G. Damonte, Anna Gasparini +5 more
1996Biochemical and Biophysical Research Communications - BBRC24 citations
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Effects in Cancer Cells of the Recombinant l-Methionine Gamma-Lyase from Brevibacterium aurantiacum. Encapsulation in Human Erythrocytes for Sustained l-Methionine Elimination
D. Machover, L. Rossi, J. Hamelin, C. Desterke +13 more
2019Journal of Pharmacology and Experimental Therapeutics23 citations Open access
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In vivo effects of dexamethasone on blood gene expression in ataxia telangiectasia
M. Menotta, S. Biagiotti, Sara Orazi, L. Rossi +6 more
2017Molecular and Cellular Biochemistry23 citations
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Targeting antiviral nucleotide analogues to macrophages
M. Magnani, L. Rossi, A. Fraternale, A. Casabianca +3 more
1997Journal of Leukocyte Biology23 citations
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Inhibition of murine retrovirus-induced immunodeficiency disease by dideoxycytidine and dideoxycytidine 5'-triphosphate.
L. Rossi, Giorgio Brandi, Alessandra Fraternale, Giuditta F. Schiavano +2 more
1993Journal of Acquired Immune Deficiency Syndromes23 citations
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A new therapy prevents intellectual disability in mouse with phenylketonuria.
T. Pascucci, L. Rossi, Marco Colamartino, Claudia Gabucci +11 more
2018Molecular Genetics and Metabolism22 citations Open access
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2',3'-Dideoxycytidine metabolism in a new drug-resistant cell line.
M. Magnani, Giorgio Brandi, A. Casabianca, Alessandra Fraternale +3 more
1995Biochemical Journal22 citations Open access
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Erythrocyte-mediated delivery of recombinant enzymes
V. Leuzzi, L. Rossi, Claudia Gabucci, F. Nardecchia +1 more
2016Journal of Inherited Metabolic Disease21 citations
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Periodic treatment with autologous erythrocytes loaded with dexamethasone 21-phosphate for fistulizing pediatric Crohn's disease: case report.
M. Castro, D. Knafelz, L. Rossi, M. Ambrosini +3 more
2006Journal of Pediatric Gastroenterology and Nutrition - JPGN21 citations Open access
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Inhibition of murine AIDS by combination of AZT and dideoxycytidine 5'-triphosphate.
A. Fraternale, A. Casabianca, L. Rossi, L. Chiarantini +4 more
1996Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology21 citations Open access
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The polymorphism of multi-drug resistance 1 gene (MDR1) does not influence the pharmacokinetics of dexamethasone loaded into autologous erythrocytes of patients with inflammatory bowel disease.
V. Annese, A. Latiano, L. Rossi, Fabrizio Bossa +6 more
2006European Review for Medical and Pharmacological Sciences20 citations
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FIV infection of macrophages: in vitro and in vivo inhibition by dideoxycytidine 5'-triphosphate.
M. Magnani, L. Rossi, Alessandra Fraternale, Lucia Silvotti +5 more
1995Veterinary Immunology and Immunopathology20 citations
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