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P. Tanswell · SciRah

Researcher profile · Semantic Scholar

P. Tanswell

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P. Tanswell — researcher profile on SciRah

h-index: 20
Works: 56
Citations: 1,894

Most-cited papers

A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer.
A. Scott, G. Wiseman, S. Welt, A. Adjei +18 more
2003Clinical Cancer Research465 citations
Semantic Scholar
Pharmacokinetics and Pharmacodynamics of Tenecteplase in Fibrinolytic Therapy of Acute Myocardial Infarction
P. Tanswell, N. Modi, D. Combs, T. Danays
2002Clinical Pharmacokinetics289 citations
Semantic Scholar
Pharmacokinetics and fibrin specificity of alteplase during accelerated infusions in acute myocardial infarction.
P. Tanswell, U. Tebbe, K. Neuhaus, Liane Gläsle-Schwarz +2 more
1992Journal of the American College of Cardiology127 citations Open access
Semantic Scholar
Pharmacokinetics and systemic effects of tissue‐type plasminogen activator in normal subjects
P. Tanswell, E. Seifried, Peter C. A. F. Su, W. Feuerer +1 more
1989Clinical pharmacology and therapy98 citations
Semantic Scholar
Pharmacokinetics and Haemostatic Status During Consecutive Infusions of Recom binant Tissue-Type Plasminogen Activator in Patients with Acute Myocardial Infarction
Erhard Seifried, P. Tanswell, D. Ellbrück, W. Haerer +1 more
1989Thrombosis and Haemostasis82 citations
Semantic Scholar
Nuclear-magnetic-resonance study of the active-site structure of yeast phosphoglycerate kinase.
P. Tanswell, E. Westhead, Robert J. P. Williams
1976European Journal of Biochemistry75 citations Open access
Semantic Scholar
Pharmacokinetics and Effects on Fibrinolytic and Coagulation Parameters of Two Doses of Recombinant Tissue-Type Plasminogen Activator in Healthy Volunteers
M. Verstraete, C.-A.-P.-F. Su, P. Tanswell, W. Feuerer +1 more
1986Thrombosis and Haemostasis73 citations
Semantic Scholar
TopFit: a PC-based pharmacokinetic/pharmacodynamic data analysis program.
P. Tanswell, J. Koup
1993International journal of clinical pharmacology, therapy and toxicology60 citations
Semantic Scholar
Pharmacokinetics of antigen and activity of recombinant tissue-type plasminogen activator after infusion in healthy volunteers.
Erhard Seifried, P. Tanswell, D. Rijken, M. Barrett-Bergshoeff +2 more
1988Arzneimittel-Forschung60 citations
Semantic Scholar
Pharmacokinetics and Pharmacodynamics of Tenecteplase: Results from a Phase II Study in Patients with Acute Myocardial Infarction
N. Modi, N. Fox, Fong Clow, P. Tanswell +3 more
2000Journal of clinical pharmacology56 citations
Semantic Scholar
Quantitative determination of the conformation of ATP in aqueous solution using the lanthanide cations as nuclear-magnetic-resonance probes.
P. Tanswell, Janet M. Thornton, Alexander V. Korda, Robert J. P. Williams
1975European Journal of Biochemistry49 citations Open access
Semantic Scholar
Pharmacokinetics and hepatic catabolism of tissue-type plasminogen activator.
P. Tanswell, E. Seifried, E. Stang, J. Krause
1991Arzneimittel-Forschung44 citations
Semantic Scholar
Comparison of Specific Antibody, D-Phe-Pro-Arg-CH2Cl and Aprotinin for Prevention of In Vitro Effects of Recombinant Tissue-Type Plasminogen Activator on Haemostasis Parameters
E. Seifried, P. Tanswell
1987Thrombosis and Haemostasis37 citations
Semantic Scholar
The internal structure of the chromaffin granule
A. Daniels, A. Korda, P. Tanswell, Alwyn Williams +1 more
1974Proceedings of the Royal Society of London. Series B. Biological Sciences30 citations
Semantic Scholar
Low Incidence of Antibodies to Recombinant Human Tissue-Type Plasminogen Activator in Treated Patients
B. R. Reed, A.-B. Chen, P. Tanswell, W. Prince +3 more
1990Thrombosis and Haemostasis29 citations
Semantic Scholar
Inhibition of yeast phosphoglycerate kinase by lanthanide—ATP complexes
P. Tanswell, E. Westhead, Robert J. P. Williams
1974FEBS Letters27 citations
Semantic Scholar
Nonlinear pharmacokinetics of tissue-type plasminogen activator in three animal species and isolated perfused rat liver.
P. Tanswell, G. Heinzel, A. Greischel, J. Krause
1990Journal of Pharmacology and Experimental Therapeutics25 citations
Semantic Scholar
Pharmacokinetics and isolated liver perfusion of carbohydrate modified recombinant tissue-type plasminogen activator
P. Tanswell, M. Schlüter, J. Krause
198925 citations
Semantic Scholar
Different receptors mediate the hepatic catabolism of tissue-type plasminogen activator and urokinase.
J. Krause, W. Seydel, G. Heinzel, P. Tanswell
1990Biochemical Journal24 citations Open access
Semantic Scholar
Fibrin degradation products are not specific markers for thrombolysis in myocardial infarction.
Erhard Seifried, P. Tanswell, D. Rijken, Cornelis Kluft +2 more
1987The Lancet23 citations
Semantic Scholar
Brain Penetration of WEB 2086 (Apafant) and Dantrolene in Mdr1a (P-Glycoprotein) and Bcrp Knockout Rats
H. Fuchs, W. Kishimoto, D. Gansser, P. Tanswell +1 more
2014Drug Metabolism And Disposition18 citations Open access
Semantic Scholar
Pharmacokinetics and pharmacodynamics of terbogrel, a combined thromboxane A2 receptor and synthase inhibitor, in healthy subjects.
B. Guth, H. Narjes, H. Schubert, P. Tanswell +2 more
2004British Journal of Clinical Pharmacology17 citations Open access
Semantic Scholar
Nonlinear pharmacokinetics of tissue‐type plasminogen activator in three animal species: a comparison of mathematical models
Keith R. Godfrey, P. Tanswell, R. A. Bates, Michael J. Chappell +1 more
1998Biopharmaceutics & drug disposition16 citations
Semantic Scholar
Biodisposition and catabolism of tissue-type plasminogen activator in rats and rabbits
C. Bakhit, D. Lewis, U. Busch, P. Tanswell +1 more
198815 citations
Semantic Scholar
Pharmacokinetic-pharmacodynamic and metabolite modeling with TopFit.
P. Tanswell, G. Heinzel, H. Weisenberger, W. Roth
1995International journal of clinical pharmacology and therapeutics13 citations
Semantic Scholar
Studies on the functionality of fibrinogen during rt-PA therapy: results of three different methods of fibrinogen determination.
Erhard Seifried, M. Oethinger, P. Tanswell, H. Nobel +1 more
1992Blood Coagulation and Fibrinolysis13 citations
Semantic Scholar
Properties of molecular variants of tissue-type plasminogen activator.
J. Krause, P. Tanswell
1989Arzneimittel-Forschung10 citations
Semantic Scholar
The Active Site of Phosphoglycerate Kinase Studied by Nuclear Magnetic Resonance
P. Tanswell, E. Westhead, R. Williams
197410 citations
Semantic Scholar
Pharmacokinetics and biodisposition of recombinant human interferon-alpha 2C in rat and marmoset.
A. Greischel, P. Tanswell, U. Busch, K. Schumacher
1988Arzneimittel-Forschung9 citations
Semantic Scholar
Steady-state intravenous pharmacokinetics of pirenzepine in patients with differing degrees of renal dysfunction
B. Krakamp, P. Tanswell, H. Vogel, G. Bozler
2004European Journal of Clinical Pharmacology8 citations
Semantic Scholar
Influence of Acute Myocardial Infarction and rt-PA Therapy on Circulating Fibrinogen
Erhard Seifried, M. Oethinger, P. Tanswell, E. Nobel +1 more
1993Thrombosis and Haemostasis8 citations
Semantic Scholar
Thrombolysis using consecutive high dose bolus and infusion of alteplase in a patient with acute massive pulmonary embolism.
U. Tebbe, Erhard Seifried, J. Carlsson, P. Tanswell
1992Blood Coagulation and Fibrinolysis8 citations
Semantic Scholar
Automated monoclonal radioimmunoassays for pirenzepine, a selective muscarinic receptor antagonist, in plasma and urine.
P. Tanswell, W. Kasper, G. Zahn
1986JIM - Journal of Immunological Methods7 citations
Semantic Scholar
Immunochemistry of bovine fibrinogen--III. Localization of two antigenic determinants in fibrinopeptide B.
P. Tanswell, Helga Stan-Lotter, Rotraut Gollwitzer, R. Timpl
1977Immunochemistry7 citations
Semantic Scholar
Current developments in thrombolytic therapy using novel plasminogen activators.
E. Seifried, P. Tanswell
1989Arzneimittel-Forschung6 citations
Semantic Scholar
A Selective Radioimmunoassay for the Determination of Pirenzepine in Plasma and Urine
C. Homon, Henry J. Esber, Paul Zavorskas, P. Tanswell +1 more
1987Therapeutic Drug Monitoring6 citations
Semantic Scholar
Absolute bioavailability of pirenzepine in intensive care patients
P. Tanswell, F. Hofgärtner, G. Bozler, H. Giesler +2 more
2004European Journal of Clinical Pharmacology5 citations
Semantic Scholar
AF‐DX 116: A Cardioselective Muscarinic Antagonist
H. Doods, W. Engel, C.-A.-P.-F. Su, P. Tanswell
19914 citations
Semantic Scholar
Immunological Approaches to the Structure of Fibrinogen
P. Tanswell, R. Gollwitzer, H. Stan-Lotter, R. Timpl
1979Thrombosis and Haemostasis4 citations
Semantic Scholar
Steady-state intravenous pharmacokinetics of pirenzepine in patients with hepatic insufficiency and combined renaland hepatic insufficiency
B. Krakamp, P. Tanswell, P. Leidig, H. Vogel +2 more
2004European Journal of Clinical Pharmacology3 citations
Semantic Scholar
Pharmacokinetics of degradation products of fibrin and fibrinogen during alteplase therapy of acute myocardial infarction
P. Tanswell, W. Nieuwenhuizen, Erhard Seifried
19933 citations
Semantic Scholar
Pharmacokinetic and pharmacodynamic studies in man simulating acute and chronic treatment with oral pirenzepine
W. Londong, V. Londong, C. Federle, P. Tanswell +1 more
2004European Journal of Clinical Pharmacology2 citations
Semantic Scholar
A Phase I Dose-Escalation Study of Sibrotuzumab in Patients with Advanced or Metastatic Fibroblast Activation Protein-positive Cancer 1
A. Scott, G. Wiseman, S. Welt, A. Adjei +17 more
20032 citations
Semantic Scholar
A Simple, Incremental Weight-Adjusted Dosing Scheme for TNK-tPA, A Bioengineered Variant of the Natural t-PA Molecule
F. Wang-Clow, N. Fox, S. Berioli, T. Danays +5 more
19982 citations
Semantic Scholar
Structure of antigenic determinants in the amino-terminal region of bovine fibrinogen Aalpha chain.
P. Tanswell, Hildegard Hildegard, R. Timpl
1978European Journal of Biochemistry2 citations Open access
Semantic Scholar
Pharmacokinetics of Human Tissue-Type Plasminogen Activator
P. Tanswell, E. Seifried, J. Krause
19911 citations
Semantic Scholar
Hepatic uptake of tissue-type plasminogen activator is saturable
J. Krause, P. Tanswell
19891 citations
Semantic Scholar
190 Dose linearity and differentiation of in vitro and in vivo effects of RT-PA on haemostatic parameters in healthy men
E. Seifried, P. Tanswell, C.-A.-P.-F. Su, W. Feuerer +2 more
19881 citations
Semantic Scholar
REPORTS ON THERAPY Pharmacokinetics and Fibrin Specificity of Alteplase During Accelerated Infusions in Acute Myocardial Infarction
P. Tanswell, U. Tebbe, K. Neuhaus, Liane GLASLE-SCHWARZ +2 more
20160 citations
Semantic Scholar
Modelling the Nonlinear Pharmacokinetics of Tissue-Type Plasminogen Activator in Three Animal Species
K. Godfrey, P. Tanswell, R. A. Bates, M. Chappell +1 more
19970 citations
Semantic Scholar

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