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C. Thibodeaux · SciRah

Researcher profile · Semantic Scholar

C. Thibodeaux

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C. Thibodeaux — researcher profile on SciRah

h-index: 17
Works: 47
Citations: 1,897

Most-cited papers

Natural-product sugar biosynthesis and enzymatic glycodiversification.
C. Thibodeaux, Charles E. Iii Melancon, Hung-Wen Liu
2008Angewandte Chemie391 citations Open access
Semantic Scholar
Unusual sugar biosynthesis and natural product glycodiversification
C. Thibodeaux, C. Melançon, Hung-Wen Liu
2007Nature301 citations
Semantic Scholar
The Enzymatic Chemistry of Cyclopropane, Epoxide, and Aziridine Biosynthesis
C. Thibodeaux, Wei-Chen Chang, Hung-Wen Liu
2011Chemical Reviews229 citations Open access
Semantic Scholar
The diverse roles of flavin coenzymes--nature's most versatile thespians.
S. Mansoorabadi, C. Thibodeaux, Hung-Wen Liu
2007Journal of Organic Chemistry177 citations Open access
Semantic Scholar
Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes
Kou-San Ju, Jiang-Tao Gao, James R. Doroghazi, Kwo-Kwang A. Wang +13 more
2015Proceedings of the National Academy of Sciences of the United States of America170 citations Open access
Semantic Scholar
Compartmentalized processing of catechols during mussel byssus fabrication determines the destiny of DOPA
Tobias Priemel, R. Palia, Margaryta Babych, C. Thibodeaux +2 more
2020Proceedings of the National Academy of Sciences of the United States of America75 citations Open access
Semantic Scholar
A Price To Pay for Relaxed Substrate Specificity: A Comparative Kinetic Analysis of the Class II Lanthipeptide Synthetases ProcM and HalM2
C. Thibodeaux, T. Ha, W. A. van der Donk
2014Journal of the American Chemical Society70 citations Open access
Semantic Scholar
Nucleophilic Participation of Reduced Flavin Coenzyme in Mechanism of UDP-galactopyranose Mutase*
H. Sun, M. Ruszczycky, Wei-Chen Chang, C. Thibodeaux +1 more
2011Journal of Biological Chemistry37 citations Open access
Semantic Scholar
Biosynthese von Naturstoffzuckern und enzymatische Glycodiversifizierung
C. Thibodeaux, C. Melançon, Hung-wen Liu
200835 citations
Semantic Scholar
The Leader Peptide Establishes Dehydration Order, Promotes Efficiency, and Ensures Fidelity During Lacticin 481 Biosynthesis
C. Thibodeaux, Josh Wagoner, Yi-Zun Yu, W. A. van der Donk
2016Journal of the American Chemical Society34 citations Open access
Semantic Scholar
Converging on a mechanism for choline degradation
C. Thibodeaux, W. A. van der Donk
2012Proceedings of the National Academy of Sciences of the United States of America33 citations Open access
Semantic Scholar
Evidence for the involvement of acid/base chemistry in the reaction catalyzed by the type II isopentenyl diphosphate/dimethylallyl diphosphate isomerase from Staphylococcus aureus.
C. Thibodeaux, S. Mansoorabadi, W. Kittleman, Wei-Chen Chang +1 more
2008Biochemistry33 citations Open access
Semantic Scholar
Characterization and mechanistic studies of type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Staphylococcus aureus.
W. Kittleman, C. Thibodeaux, Yung-Nan Liu, Hua Zhang +1 more
2007Biochemistry33 citations Open access
Semantic Scholar
Enzymatic Synthesis of TDP-deoxysugars
J. White-Phillip, C. Thibodeaux, Hung-Wen Liu
2009Methods in Enzymology27 citations Open access
Semantic Scholar
Linear Free Energy Relationships Demonstrate a Catalytic Role for the Flavin Mononucleotide Coenzyme of the Type II Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase
C. Thibodeaux, Wei-Chen Chang, Hung-Wen Liu
2010Journal of the American Chemical Society26 citations Open access
Semantic Scholar
Glyco-stripping and glyco-swapping.
C. Melançon, C. Thibodeaux, Hung-Wen Liu
2006ACS Chemical Biology20 citations
Semantic Scholar
Manipulating nature's sugar biosynthetic machineries for glycodiversification of macrolides: Recent advances and future prospects
C. Thibodeaux, Hung-Wen Liu
200718 citations Open access
Semantic Scholar
Structural Dynamics of Cytochrome P450 3A4 in the Presence of Substrates and Cytochrome P450 Reductase
J. Ducharme, I. Sevrioukova, C. Thibodeaux, K. Auclair
2021bioRxiv16 citations Open access
Semantic Scholar
Insights into the Dynamic Structural Properties of a Lanthipeptide Synthetase using Hydrogen-Deuterium Exchange Mass Spectrometry.
Yeganeh Habibi, Kevin A. Uggowitzer, Hassan Issak, C. Thibodeaux
2019Journal of the American Chemical Society16 citations
Semantic Scholar
Mechanistic Studies of 1-Aminocyclopropane-1-carboxylate Deaminase (ACCD): Characterization of an Unusual PLP-dependent Reaction
C. Thibodeaux, Hung-Wen Liu
2011Biochemistry15 citations Open access
Semantic Scholar
Stereochemical Studies of the Type II Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase Implicate the FMN Coenzyme in Substrate Protonation
J. Calveras, C. Thibodeaux, S. Mansoorabadi, Hung-Wen Liu
2011ChemBioChem14 citations Open access
Semantic Scholar
Partially Modified Peptide Intermediates in Lanthipeptide Biosynthesis Alter the Structure and Dynamics of a Lanthipeptide Synthetase.
Yeganeh Habibi, Nuwani W Weerasinghe, Kevin A. Uggowitzer, C. Thibodeaux
2022Journal of the American Chemical Society13 citations
Semantic Scholar
The Type II Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase (IDI-2): A Model for Acid/Base Chemistry in Flavoenzyme Catalysis
C. Thibodeaux, Hung-Wen Liu
2017Archives of Biochemistry and Biophysics13 citations Open access
Semantic Scholar
A conserved SH3-like fold in diverse putative proteins tetramerizes into an oxidoreductase providing an antimicrobial resistance phenotype
Claudèle Lemay-St-Denis, Lorea Alejaldre, Zakaria Jemouai, Kiana Lafontaine +10 more
2023Philosophical Transactions of the Royal Society of London. Biological Sciences11 citations Open access
Semantic Scholar
The conformationally dynamic structural biology of lanthipeptide biosynthesis.
C. Thibodeaux
2023Current Opinion in Structural Biology10 citations
Semantic Scholar
A Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Platform for Investigating Peptide Biosynthetic Enzymes.
Yeganeh Habibi, C. Thibodeaux
2020Journal of Visualized Experiments9 citations
Semantic Scholar
Editors’ Choice—A Miniaturized Enzymatic Biosensor for Detection of Sensory-Evoked D-serine Release in the Brain
Siba Moussa, M. R. Van Horn, Aryan Shah, L. Pollegioni +3 more
20218 citations Open access
Semantic Scholar
Mutations in Dynamic Structural Elements Alter the Kinetics and Fidelity of the Multifunctional Class II Lanthipeptide Synthetase, HalM2.
Kevin A. Uggowitzer, Yeganeh Habibi, Wanlei Wei, N. Moitessier +1 more
2021Biochemistry8 citations
Semantic Scholar
Exploring the conformational landscape of a lanthipeptide synthetase using native mass spectrometry
Nuwani W Weerasinghe, Yeganeh Habibi, Kevin A. Uggowitzer, C. Thibodeaux
2020bioRxiv8 citations Open access
Semantic Scholar
3.20 – Complementary Routes to Natural Product Glycodiversification: Pathway Engineering and Glycorandomization
C. Thibodeaux, H.-W. Liu
20078 citations
Semantic Scholar
Combining Small-Molecule Bioconjugation and Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) to Expose Allostery: the Case of Human Cytochrome P450 3A4.
J. Ducharme, V. Polić, C. Thibodeaux, K. Auclair
2021ACS Chemical Biology7 citations Open access
Semantic Scholar
Defining the functional properties of cyclopropane fatty acid synthase from Pseudomonas aeruginosa PAO1
Vivian Ezeduru, A. R. Shao, F. A. Venegas, Geoffrey Mckay +3 more
2024Journal of Biological Chemistry6 citations Open access
Semantic Scholar
Unraveling the mechanisms of isoprenoid biosynthetic enzymes: mechanistic studies of the early stage enzymes
C. Thibodeaux, Hung-Wen Liu
20096 citations Open access
Semantic Scholar
Purification, crystallization and crystallographic analysis of the PorX response regulator associated with the type IX secretion system.
Anshu Saran, Nuwani W Weerasinghe, C. Thibodeaux, N. Zeytuni
2022Acta Crystallographica Section F Structural Biology Communications4 citations Open access
Semantic Scholar
Biochemical and biophysical investigation of the HalM2 lanthipeptide synthetase using mass spectrometry
Sally R Hamry, C. Thibodeaux
2021Canadian journal of chemistry (Print)4 citations Open access
Semantic Scholar
Evaluation of Quatsome Morphology, Composition, and Stability for Pseudomonas aeruginosa Biofilm Eradication.
Changyue Du, Sascha N. Woolcott, A. Wahba, Sally R Hamry +4 more
2024Langmuir3 citations
Semantic Scholar
Exploring the Heterogeneous Structural Dynamics of Class II Lanthipeptide Synthetases with Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS).
Kevin A. Uggowitzer, A. R. Shao, Yeganeh Habibi, Qianyi E Zhang +1 more
2022Biochemistry3 citations
Semantic Scholar
Cycling back to biocatalysis
M. A. Attia, C. Thibodeaux
2020Nature Catalysis3 citations
Semantic Scholar
Asymmetric loading of TnsE regulates Tn7 targeting of DNA replication structures
Shreya S. Krishnan, Yao Shen, Treasa B. O'Hagan, Lindsay A. Matthews +4 more
2025Nucleic Acids Research2 citations Open access
Semantic Scholar
Unraveling flavoenzyme reaction mechanisms using flavin analogues and linear free energy relationships.
C. Thibodeaux, Wei-Chen Chang, Hung-Wen Liu
2019Methods in Enzymology2 citations
Semantic Scholar
Excavation Time for the Vedra and Maumee Channels (Mars) by Application of Equilibrium Sediment Transport Theory
D. Hon, P. Washington, C. Thibodeaux
20032 citations
Semantic Scholar
GRAIN-SIZE ANALYSIS OF MAUMEE AND VEDRA CHANNEL SEDIMENTS (MARS) USING EQUILIBRIUM SEDIMENT TRANSPORT THEORY
C. Thibodeaux, P. Washington, D. Hon, M. Vallès +1 more
20031 citations
Semantic Scholar
Combining small-molecule bioconjugation and hydrogen-deuterium exchange mass spectrometry (HDX-MS) to expose allostery: the case of human cytochrome P450 3A4
J. Ducharme, C. Thibodeaux, K. Auclair
2020bioRxiv0 citations Open access
Semantic Scholar
Mechanistic Studies of 1-Aminocyclopropane-1-carboxylate Deaminase (ACCD): Characterization of an Unusual PLP-dependent Reaction
C. Thibodeaux, Hung-Wen Liu
20110 citations
Semantic Scholar
Mechanistic studies of two enzymes that employ common coenzymes in uncommon ways
C. Thibodeaux
20100 citations
Semantic Scholar
Determining Water Levels in Maumee and Vedra Valles Using Equilibrium Sediment Transport Theory
C. Thibodeaux, P. Washington, D. Hon
20030 citations
Semantic Scholar
BOSTON CANAL/VERMILION BAY SHORELINE PROTECTION T/V-09 Second Priority List Shoreline Protection Project of the Coastal Wetlands Planning, Protection, and Restoration Act (Public Law 101-646)
C. Thibodeaux
19980 citations
Semantic Scholar

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Yeganeh Habibi×6
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Wei-Chen Chang×5
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Kevin A. Uggowitzer×5
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Nuwani W Weerasinghe×5

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C. Melançon×3

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J. Ducharme — researcher profile on SciRah

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