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F. Al-Mohanna · SciRah

Researcher profile · Semantic Scholar

F. Al-Mohanna

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F. Al-Mohanna — researcher profile on SciRah

h-index: 17
Works: 51
Citations: 1,265

Most-cited papers

PD‐L1 promotes OCT4 and Nanog expression in breast cancer stem cells by sustaining PI3K/AKT pathway activation
S. Almozyan, D. Çolak, Fatmah A. Mansour, A. Alaiya +5 more
2017International Journal of Cancer224 citations Open access
Semantic Scholar
Microvascular Injury, Thrombosis, Inflammation, and Apoptosis in the Pathogenesis of Heatstroke: A Study in Baboon Model
George T. Roberts, H. Ghebeh, M. Chishti, F. Al-Mohanna +3 more
2008Arteriosclerosis, Thrombosis and Vascular Biology164 citations Open access
Semantic Scholar
PD-L1 is overexpressed on breast cancer stem cells through notch3/mTOR axis
Fatmah A. Mansour, Amer Al-Mazrou, F. Al-Mohanna, M. Al-Alwan +1 more
2020Oncoimmunology87 citations Open access
Semantic Scholar
Fascin Is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self‐Renewal Pathway
Rayanah Barnawi, Samiyah Al-Khaldi, Ghida Majed Sleiman, A. Sarkar +4 more
2016Stem Cells75 citations Open access
Semantic Scholar
Fascin is involved in the chemotherapeutic resistance of breast cancer cells predominantly via the PI3K/Akt pathway
H. Ghebeh, Samiyah Al-Khaldi, S. Olabi, A. Al‐Dhfyan +6 more
2014British Journal of Cancer75 citations Open access
Semantic Scholar
Profiling of normal and malignant breast tissue show CD44high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers
H. Ghebeh, Ghida Majed Sleiman, P. Manogaran, Amer Al-Mazrou +5 more
2013BMC Cancer74 citations Open access
Semantic Scholar
Tocilizumab potentiates cisplatin cytotoxicity and targets cancer stem cells in triple-negative breast cancer.
Noura N. Alraouji, F. Al-Mohanna, H. Ghebeh, M. Arafah +3 more
2020Molecular Carcinogenesis58 citations
Semantic Scholar
Pleiotropic Effects of YC-1 Selectively Inhibit Pathological Retinal Neovascularization and Promote Physiological Revascularization in a Mouse Model of Oxygen-Induced Retinopathy
Michael Deniro, A. Al-Halafi, F. Al-Mohanna, O. Alsmadi +1 more
2010Molecular Pharmacology51 citations
Semantic Scholar
Tissue factor/factor VIIa pathway mediates coagulation activation in induced-heat stroke in the baboon
A. Bouchama, F. Al-Mohanna, Lina Assad, E. Baturcam +3 more
2012Critical Care Medicine50 citations
Semantic Scholar
Interleukin-8 Activates Breast Cancer-Associated Adipocytes and Promotes Their Angiogenesis- and Tumorigenesis-Promoting Effects
Huda H. Al-Khalaf, Bothaina Al-Harbi, A. Al-Sayed, M. Arafah +4 more
2018Molecular and Cellular Biology49 citations Open access
Semantic Scholar
The DNA methyl-transferase protein DNMT1 enhances tumor-promoting properties of breast stromal fibroblasts
Layla A. Al-Kharashi, F. Al-Mohanna, A. Tulbah, A. Aboussekhra
2017OncoTarget38 citations Open access
Semantic Scholar
Breast stromal fibroblasts from histologically normal surgical margins are pro-carcinogenic
Maha A. Al-Rakan, D. Çolak, Siti‐Faujiah Hendrayani, A. Al‐Bakheet +4 more
2013Journal of Pathology35 citations Open access
Semantic Scholar
Modulating the hypoxia-inducible factor signaling pathway as a therapeutic modality to regulate retinal angiogenesis.
Michael Deniro, O. Alsmadi, F. Al-Mohanna
2009Experimental Eye Research34 citations
Semantic Scholar
Decorin (DCN) Downregulation Activates Breast Stromal Fibroblasts and Promotes Their Pro-Carcinogenic Effects through the IL-6/STAT3/AUF1 Signaling
Wafaa A. Aljagthmi, M. Alasmari, Maha H. Daghestani, Layla A Alkharashi +2 more
2024Cells22 citations Open access
Semantic Scholar
FOXP3+ regulatory T cell ameliorates microvasculature in the rejection of mouse orthotopic tracheal transplants.
M. Khan, Fatimah M Alanazi, H. Ahmed, F. Al-Mohanna +2 more
2017Clinical Immunology18 citations
Semantic Scholar
Inhibition of Reactive Gliosis Prevents Neovascular Growth in the Mouse Model of Oxygen-Induced Retinopathy
Michael Deniro, F. Al-Mohanna, F. Al-Mohanna
2011PLoS ONE18 citations Open access
Semantic Scholar
Deletion of low molecular weight protein tyrosine phosphatase (Acp1) protects against stress‐induced cardiomyopathy
Fallou Wade, Pearl J. Quijada, Kamar Al-Haffar, S. Awad +17 more
2015Journal of Pathology17 citations Open access
Semantic Scholar
Obesity and p16INK4A Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity
Huda H. Al-Khalaf, Mrad Amir, F. Al-Mohanna, A. Tulbah +2 more
2017Molecular and Cellular Biology15 citations Open access
Semantic Scholar
The Nexus between VEGF and NFκB Orchestrates a Hypoxia-Independent Neovasculogenesis
Michael Deniro, F. Al-Mohanna, O. Alsmadi, F. Al-Mohanna
2013PLoS ONE15 citations Open access
Semantic Scholar
AUF1 promotes stemness in human mammary epithelial cells through stabilization of the EMT transcription factors TWIST1 and SNAIL1
Manar M. AlAhmari, Huda H. Al-Khalaf, F. Al-Mohanna, H. Ghebeh +1 more
2020Oncogenesis14 citations Open access
Semantic Scholar
Overexpression of the pro‐protein convertase furin predicts prognosis and promotes papillary thyroid carcinoma progression and metastasis through RAF/MEK signaling
P. Poyil, A. K. Siraj, D. Padmaja, S. Parvathareddy +8 more
2023Molecular Oncology12 citations Open access
Semantic Scholar
The curcumin analogue PAC has potent anti-anaplastic thyroid cancer effects
M. Al-Mohanna, Noura N. Alraouji, S. Alhabardi, F. Al-Mohanna +3 more
2023Scientific Reports12 citations Open access
Semantic Scholar
High AUF1 level in stromal fibroblasts promotes carcinogenesis and chemoresistance and predicts unfavorable prognosis among locally advanced breast cancer patients
T. Al-Tweigeri, Noura N. Alraouji, A. Tulbah, M. Arafah +6 more
2022Breast Cancer Research12 citations Open access
Semantic Scholar
Ovarian tumor cell-derived JAGGED2 promotes omental metastasis through stimulating the Notch signaling pathway in the mesothelial cells
Syed S. Islam, F. Al-Mohanna, Iman M Yousef, I. Al-Badawi +1 more
2024Cell Death and Disease10 citations Open access
Semantic Scholar
Crosstalk between aryl hydrocarbon receptor (AhR) and BCL-2 pathways suggests the use of AhR antagonist to maintain normal differentiation state of mammary epithelial cells during BCL-2 inhibition therapy
A. Al‐Dhfyan, A. Alaiya, F. Al-Mohanna, M. Attwa +3 more
2022Journal of Advanced Research10 citations Open access
Semantic Scholar
Tocilizumab suppresses the pro-carcinogenic effects of breast cancer- associated fibroblasts through inhibition of the STAT3/AUF1 pathway.
N. Al-Jomah, F. Al-Mohanna, A. Aboussekhra
2021Carcinogenesis10 citations
Semantic Scholar
Kinome inhibition reveals a role for polo‐like kinase 1 in targeting post‐transcriptional control in cancer
Q. H. Al-Qahtani, W. Moghrabi, Suhad Al-Yahya, Latifa Al-Haj +7 more
2021Molecular Oncology10 citations Open access
Semantic Scholar
Induction of cell proliferation in old rat liver can reset certain gene expression levels characteristic of old liver to those associated with young liver
M. Chishti, N. Kaya, A. BinBakheet, F. Al-Mohanna +2 more
2012AGE10 citations Open access
Semantic Scholar
Ionizing radiation normalizes the features of active breast cancer stromal fibroblasts and suppresses their paracrine pro-carcinogenic effects
A. Aboussekhra, Noura N. Alraouji, F. Al-Mohanna, Huda H. Al-Khalaf
2023Translational Oncology9 citations Open access
Semantic Scholar
Osteoprotegerin (OPG) mediates the anti-carcinogenic effects of normal breast fibroblasts and targets cancer stem cells through inhibition of the β-catenin pathway.
Noura N. Alraouji, S. Hendrayani, H. Ghebeh, F. Al-Mohanna +1 more
2021Cancer Letters8 citations
Semantic Scholar
Target β-catenin/CD44/Nanog axis in colon cancer cells by certain N'-(2-oxoindolin-3-ylidene)-2-(benzyloxy)benzohydrazides.
A. Radwan, F. Al-Mohanna, F. Alanazi, P. Manogaran +1 more
2016Bioorganic & Medicinal Chemistry Letters8 citations Open access
Semantic Scholar
Endogenous osteoprotegerin (OPG) represses ERα and promotes stemness and chemoresistance in breast cancer cells
Noura N. Alraouji, Dilek Colak, F. Al-Mohanna, A. Alaiya +1 more
2024Cell Death Discovery6 citations Open access
Semantic Scholar
Pleiotropic Effects of YC-1 Attenuates Pathological Retinal Neovascularization
Michael Deniro, F. Al-Mohanna, O. Alsmadi, A. Al-Halafi
20093 citations
Semantic Scholar
E2F1 activates breast stromal fibroblasts and promotes their paracrine pro-carcinogenic effects
Layla A. Al-Kharashi, F. Al-Mohanna, A. Aboussekhra, Abdelilah Abousekhra
2025Scientific Reports2 citations Open access
Semantic Scholar
Interleukin-8 Dedifferentiates Primary Human Luminal Cells to Multipotent Stem Cells
Huda H. Al-Khalaf, H. Ghebeh, S. Wakil, F. Al-Mohanna +1 more
2020Molecular and Cellular Biology2 citations Open access
Semantic Scholar
Profiling of normal and malignant breast tissue show CD44high/CD24lowphenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers
H. Ghebeh, Ghida Majed Sleiman, P. Manogaran, Amer Al-Mazrou +5 more
2013BMC Cancer2 citations Open access
Semantic Scholar
Recombinant Human Decorin Normalizes the Active Features of Breast Cancer-Associated Fibroblasts
Wafaa A. Aljagthmi, A. Alaiya, Maha H. Daghestani, F. Al-Mohanna +1 more
2026Cells1 citations Open access
Semantic Scholar
A Novel Surgical Technique in a Sheep Model for Suburethral Graft Implantation.
R. Seyam, Christopher R. Chapple, Omar Alsulaiman, F. Al-Mohanna +2 more
2025Journal of Visualized Experiments1 citations
Semantic Scholar
Sheep as a Model for Liver Transplantation
Mohammed Alsebayel, Y. Elsheikh, F. Al-Mohanna, Saleh Al-Abbad +3 more
2023Cureus1 citations Open access
Semantic Scholar
S100A3 Regulates the Expression of Telomerase Reverse Transcriptase (TERT)
S. A. Al Qattan, F. Al-Mohanna, V. Raveendran, R. Abdulqawi +2 more
2023A66. DISSECTING THE MATRIX AND MESENCHYMAL CELLS IN FIBROSIS1 citations
Semantic Scholar
The use of ex-vivo liver perfusion circuit in sheep model
M. Al-Sebayel, Y. Elsheikh, F. Al-Mohanna, Saleh Al-Abbad +5 more
2021Saudi Medical Journal1 citations Open access
Semantic Scholar
Induction of cell proliferation in old rat liver can reset certain gene expression levels characteristic of old liver to those associated with young liver
M. Chishti, N. Kaya, A. BinBakheet, F. Al-Mohanna +2 more
2012AGE1 citations Open access
Semantic Scholar
Dual Targeting of Retinal Vasculature: YC-1 Selectively Mediates Retinal Vascular Remodeling in the Ischemic Retina and Exhibits Potent Inhibitory Effects on Retinal Neovascularization in a Mouse Model of OIR
Michael Deniro, A. Al-Halafi, F. Al-Mohanna, O. Alsmadi +1 more
20101 citations
Semantic Scholar
Withaferin A Inhibits the Angiogenic Promoting Effect of active Breast Adipocytes through Targeting CXCR1/2/IL-8 Axis
Huda H. Al-Khalaf, B. Alharbi, F. Al-Mohanna, A. Aboussekhra
2026Journal of Biotechnology and Biomedicine0 citations Open access
Semantic Scholar
Eugenoplatin (a phyto-chemo drug conjugate) targets cancer stem cells through inhibition of the β-catenin signaling in triple-negative breast cancer cells
Noura N. Alraouji, Basem Alotaibi, Mohd Yasir Khan, F. Al-Mohanna +6 more
2026Journal of Translational Medicine0 citations Open access
Semantic Scholar
A critical comparison of polypropylene and polyurethane sling materials after implantation in a suburethral sheep model.
A. Bullock, David A. Gregory, R. Seyam, F. Al-Mohanna +6 more
2025Biomaterials0 citations
Semantic Scholar
Abstract 539: Furin predicts prognosis and promotes PTC progression and metastasis via MEK-ERK axis
P. Poyil, A. K. Siraj, D. Padmaja, S. Parvathareddy +9 more
2023Cancer Research0 citations
Semantic Scholar
Obesity and p 16 INK 4 A down-regulation activate breast adipocytes 1 and promote their pro-tumorigenicity 2 3 Running title : Obesity activates breast adipocytes
Huda H. Al-Khalaf, Mrad Amir, F. Al-Mohanna, A. Tulbah +2 more
20170 citations
Semantic Scholar
Targeting Zinc Transporter-8 as a Therapeutic Approach in Ischemic Retinopathy
Michael Deniro, F. Al-Mohanna, F. Al-Mohanna
20120 citations
Semantic Scholar
Reversal of Reactive Gliosis Promote De Novo Vascular Remodeling and Prevent Retinal Vasculopathies
Michael Deniro, F. Al-Mohanna, F. Al-Mohanna
20110 citations
Semantic Scholar

Frequent co-authors

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A. Aboussekhra×20
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A. Aboussekhra — researcher profile on SciRah
H. Ghebeh×11
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H. Ghebeh — researcher profile on SciRah
A. Tulbah×8
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A. Tulbah — researcher profile on SciRah
Michael Deniro×8
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Michael Deniro — researcher profile on SciRah

×7

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F. Al-Mohanna — researcher profile on SciRah

Noura N. Alraouji×7

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Noura N. Alraouji — researcher profile on SciRah

Huda H. Al-Khalaf×7

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Huda H. Al-Khalaf — researcher profile on SciRah

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A. Alaiya — researcher profile on SciRah

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D. Çolak — researcher profile on SciRah

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O. Alsmadi — researcher profile on SciRah

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M. Al-Alwan — researcher profile on SciRah

Amer Al-Mazrou×4

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Amer Al-Mazrou — researcher profile on SciRah