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M. Attwa · SciRah

Researcher profile · Semantic Scholar

M. Attwa

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M. Attwa — researcher profile on SciRah

h-index: 27
Works: 156
Citations: 1,826

Most-cited papers

Exploring the Chemical Reactivity, Molecular Docking, Molecular Dynamic Simulation and ADMET Properties of a Tetrahydrothienopyridine Derivative Using Computational Methods
A. Bakheit, M. Attwa, A. Kadi, H. Ghabbour +1 more
2023Crystals48 citations Open access
Semantic Scholar
Metabolic Stability Assessment of New PARP Inhibitor Talazoparib Using Validated LC–MS/MS Methodology: In silico Metabolic Vulnerability and Toxicity Studies
M. Attwa, A. Kadi, A. Abdelhameed, H. Alhazmi
2020Drug Design, Development and Therapy38 citations Open access
Semantic Scholar
Phase I metabolic profiling and unexpected reactive metabolites in human liver microsome incubations of X-376 using LC-MS/MS: bioactivation pathway elucidation and in silico toxicity studies of its metabolites
M. Attwa, A. Kadi, A. Abdelhameed
2020RSC Advances34 citations Open access
Semantic Scholar
The Synthesis, In Vitro Bio-Evaluation, and In Silico Molecular Docking Studies of Pyrazoline–Thiazole Hybrid Analogues as Promising Anti-α-Glucosidase and Anti-Urease Agents
Y. Khan, Shoaib Khan, Rafaqat Hussain, A. Maalik +5 more
2023Pharmaceuticals33 citations Open access
Semantic Scholar
Structural Analysis and Reactivity Insights of (E)-Bromo-4-((4-((1-(4-chlorophenyl)ethylidene)amino)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)-5-((2-isopropylcyclohexyl)oxy) Furan-2(5H)-one: A Combined Approach Using Single-Crystal X-ray Diffraction, Hirshfeld Surface Analysis, and Conceptual Density Fun
A. Bakheit, M. Attwa, A. Kadi, H. Alkahtani
2023Crystals23 citations Open access
Semantic Scholar
An UPLC–ESI–MS/MS Bioanalytical Methodology for the Quantification of Gilteritinib in Human Liver Microsomes: Application to In Vitro and In Silico Metabolic Stability Estimation
M. Attwa, H. Alrabiah, Aishah M. Alsibaee, A. Abdelhameed +1 more
2023Separations21 citations Open access
Semantic Scholar
An Ultra-Fast Validated Green UPLC-MS/MS Approach for Assessing Revumenib in Human Liver Microsomes: In Vitro Absorption, Distribution, Metabolism, and Excretion and Metabolic Stability Evaluation
M. Attwa, A. Abdelhameed, A. Kadi
2024Medicina20 citations
Semantic Scholar
Identification of Indazole-Based Thiadiazole-Bearing Thiazolidinone Hybrid Derivatives: Theoretical and Computational Approaches to Develop Promising Anti-Alzheimer’s Candidates
Y. Khan, Shoaib Khan, Rafaqat Hussain, W. Rehman +6 more
2023Pharmaceuticals20 citations Open access
Semantic Scholar
A validated LC-MS/MS analytical method for the quantification of pemigatinib: metabolic stability evaluation in human liver microsomes
M. Attwa, A. Abdelhameed, Nawaf A. Alsaif, A. Kadi +1 more
2022RSC Advances20 citations Open access
Semantic Scholar
A Rapid and Sensitive UPLC-MS/MS Method for Quantifying Capmatinib in Human Liver Microsomes: Evaluation of Metabolic Stability by In Silico and In Vitro Analysis
M. Attwa, A. Abdelhameed, Aishah M. Alsibaee, A. Kadi
2023Separations19 citations Open access
Semantic Scholar
Estimation of zorifertinib metabolic stability in human liver microsomes using LC-MS/MS.
M. Attwa, Nasser S Al-Shakliah, H. Alrabiah, A. Kadi +1 more
2022Journal of Pharmaceutical and Biomedical Analysis16 citations
Semantic Scholar
An ultra-fast ultra-high-performance liquid chromatography-tandem mass spectrometry method for estimating the in vitro metabolic stability of palbociclib in human liver microsomes: In silico study for metabolic lability, absorption, distribution, metabolism, and excretion features, and DEREK alerts
M. Attwa, A. Abdelhameed, A. Kadi
2024Journal of Separation Science15 citations
Semantic Scholar
Development of a Fast and Sensitive UPLC–MS/MS Analytical Methodology for Fenebrutinib Estimation in Human Liver Microsomes: In Vitro and In Silico Metabolic Stability Evaluation
M. Attwa, Aishah M. Alsibaee, Haya I. Aljohar, A. Abdelhameed +1 more
2023Separations14 citations Open access
Semantic Scholar
Development of novel univariate and multivariate validated chemometric methods for the analysis of dasatinib, sorafenib, and vandetanib in pure form, dosage forms and biological fluids.
A. Abdelhameed, M. Attwa, M. Attia, A. Alanazi +2 more
2021Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy14 citations
Semantic Scholar
An Ultra-Fast Green UHPLC-MS/MS Method for Assessing the In Vitro Metabolic Stability of Dovitinib: In Silico Study for Absorption, Distribution, Metabolism, Excretion, Metabolic Lability, and DEREK Alerts
M. Attwa, A. Abdelhameed, A. Kadi
2024Medicina13 citations Open access
Semantic Scholar
Development of an LC-MS/MS Method for Quantification of Sapitinib in Human Liver Microsomes: In Silico and In Vitro Metabolic Stability Evaluation
M. Attwa, H. Alrabiah, G. A. Mostafa, A. Kadi
2023Molecules13 citations Open access
Semantic Scholar
Simple and efficient spectroscopic-based univariate sequential methods for simultaneous quantitative analysis of vandetanib, dasatinib, and sorafenib in pharmaceutical preparations and biological fluids.
A. Abdelhameed, Eman S. G. Hassan, M. Attwa, Nasser S Al-Shakliah +2 more
2021Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy13 citations
Semantic Scholar
Enhanced Codelivery of Gefitinib and Azacitidine for Treatment of Metastatic-Resistant Lung Cancer Using Biodegradable Lipid Nanoparticles
E. Elzayat, Abdelrahman Y. Sherif, F. Nasr, M. Attwa +3 more
2023Materials12 citations Open access
Semantic Scholar
Spectroscopic, molecular docking and dynamic simulation studies of binding between the new anticancer agent olmutinib and human serum albumin
A. Alanazi, A. Bakheit, M. Attwa, A. Abdelhameed
2021Journal of Biomolecular Structure and Dynamics12 citations
Semantic Scholar
A Validated LC–MS/MS Assay for the Simultaneous Quantification of the FDA-Approved Anticancer Mixture (Encorafenib and Binimetinib): Metabolic Stability Estimation
M. Attwa, H. Darwish, Nasser S Al-Shakliah, A. Kadi
2021Molecules12 citations Open access
Semantic Scholar
Detection and characterization of simvastatin and its metabolites in rat tissues and biological fluids using MALDI high resolution mass spectrometry approach
Wencui Yin, Reem I. Al-Wabli, M. Attwa, A. M. Motiur Rahman +1 more
2022Scientific Reports11 citations Open access
Semantic Scholar
LC-MS/MS method for the quantification of the anti-cancer agent infigratinib: Application for estimation of metabolic stability in human liver microsomes.
G. A. Mostafa, A. Kadi, N. AlMasoud, M. Attwa +2 more
2021Journal of chromatography. B, Analytical technologies in the biomedical and life sciences11 citations
Semantic Scholar
Characterization of the in vitro metabolic profile of nazartinib in HLMs using UPLC-MS/MS method: In silico metabolic lability and DEREK structural alerts screening using StarDrop software
M. Attwa, A. Abdelhameed, A. Kadi
2024Heliyon10 citations Open access
Semantic Scholar
Ultra-fast UPLC-MS/MS approach for estimating X-376 in human liver microsomes: Evaluation of metabolic stability via in silico software and in vitro analysis.
M. Attwa, A. Abdelhameed, A. Kadi
2024Journal of pharmacological and toxicological methods10 citations
Semantic Scholar
An LC–MS/MS Analytical Method for Quantifying Tepotinib in Human Liver Microsomes: Application to In Vitro and In Silico Metabolic Stability Estimation
M. Attwa, G. A. Mostafa, H. Alrabiah, A. Kadi
2023Separations10 citations Open access
Semantic Scholar
Vandetanib.
Ahmed I. Al-Ghusn, A. Bakheit, M. Attwa, H. Alrabiah
2023Profiles of Drug Substances, Excipients and Related Methodology10 citations
Semantic Scholar
Crosstalk between aryl hydrocarbon receptor (AhR) and BCL-2 pathways suggests the use of AhR antagonist to maintain normal differentiation state of mammary epithelial cells during BCL-2 inhibition therapy
A. Al‐Dhfyan, A. Alaiya, F. Al-Mohanna, M. Attwa +3 more
2022Journal of Advanced Research10 citations Open access
Semantic Scholar
Polycaprolactone—Vitamin E TPGS Micellar Formulation for Oral Delivery of Paclitaxel
Ziyad Binkhathlan, Raisuddin Ali, Osman B. Yusuf, Abdullah H. Alomrani +6 more
2024Polymers9 citations Open access
Semantic Scholar
Piperazine ring toxicity in three novel anti-breast cancer drugs: an in silico and in vitro metabolic bioactivation approach using olaparib as a case study
Thamer A. Alsubi, M. Attwa, H. Darwish, Hatem A. Abuelizz +1 more
2023Naunyn-Schmiedeberg's Archives of Pharmacology9 citations
Semantic Scholar
Development and validation of an UPLC-ESI-MS/MS method for quantification of duvelisib in plasma: application to pharmacokinetic study in rats
I. Darwish, N. Alzoman, A. Almomen, Abdulrahman A. Almehizia +3 more
2023RSC Advances8 citations Open access
Semantic Scholar
Nicotine and cotinine quantification after a 4-week inhalation of electronic cigarette vapors in male and female mice using UPLC-MS/MS
F. Alasmari, A. Alasmari, E. Elzayat, M. Alotaibi +8 more
2022Saudi Medical Journal8 citations Open access
Semantic Scholar
A Rapid and Sensitive Liquid Chromatography-Tandem Mass Spectrometry Bioanalytical Method for the Quantification of Encorafenib and Binimetinib as a First-Line Treatment for Advanced (Unresectable or Metastatic) Melanoma—Application to a Pharmacokinetic Study
M. Hefnawy, Mohamed M. Alanazi, Abdullah M. Al-Hossaini, Abdulaziz I Alnasser +4 more
2022Molecules8 citations Open access
Semantic Scholar
A Green Approach: Optimization of the UPLC Method Using DoE Software for Concurrent Quantification of Pioglitazone and Dapagliflozin in a SNEDDS Formulation for the Treatment of Diabetes
E. Elzayat, Abdelrahman Y. Sherif, M. Attwa, Mohammad A. Altamimi
2024ACS Omega7 citations Open access
Semantic Scholar
Fabrication and Applications of Potentiometric Membrane Sensors Based on γ-Cyclodextrin and Calixarene as Ionophores for the Determination of a Histamine H1-Receptor Antagonist: Fexofenadine
H. Alrabiah, Essam A. Ali, Rashad Alsalahi, M. Attwa +1 more
2023Polymers7 citations Open access
Semantic Scholar
Supramolecular Structure, Hirshfeld Surface Analysis, Morphological Study and DFT Calculations of the Triphenyltetrazolium Cobalt Thiocyanate Complex
Essam A. Ali, Rim Bechaieb, Rashad Al-Salahi, Ahmed S. M. Al-Janabi +2 more
2023Crystals7 citations Open access
Semantic Scholar
Assessment of In Silico and In Vitro Selpercatinib Metabolic Stability in Human Liver Microsomes Using a Validated LC-MS/MS Method
M. Attwa, H. Alrabiah, G. A. Mostafa, A. Bakheit +1 more
2023Molecules7 citations Open access
Semantic Scholar
Identification and characterization of in vitro, in vivo, and reactive metabolites of tandutinib using liquid chromatography ion trap mass spectrometry.
Nasser S Al-Shakliah, M. Attwa, H. Alrabiah, A. Kadi
2021Analytical Methods7 citations
Semantic Scholar
Metabolic Stability Assessment of Larotrectinib Using Liquid Chromatography Tandem Mass Spectrometry
M. Attwa, A. Kadi, H. Darwish
2020Drug Design, Development and Therapy7 citations Open access
Semantic Scholar
An ultra-fast green ultra-high-performance liquid chromatography-tandem mass spectrometry method for estimating the in vitro metabolic stability of zotizalkib in human liver microsomes.
M. Attwa, A. Abdelhameed, A. Kadi
2024Journal of Separation Science6 citations
Semantic Scholar
Development and Validation of a Rapid LC-MS/MS Method for Quantifying Alvocidib: In Silico and In Vitro Metabolic Stability Estimation in Human Liver Microsomes
M. Attwa, H. Alrabiah, A. Kadi
2023Molecules6 citations Open access
Semantic Scholar
LC–MS/MS method for the quantitation of decitabine and venetoclax in rat plasma after SPE: Application to pharmacokinetic study
Abdulaziz I Alnasser, Mohamed M. Hefnawy, Abdullah M. Al-Hossaini, Yousef A. Bin Jardan +6 more
2023Saudi Pharmaceutical Journal6 citations Open access
Semantic Scholar
A Novel Green Micellar HPLC-UV Method for the Estimation of Vandetanib in Pure Form, Human Urine, Human Plasma and Human Liver Microsomes Matrices with Application to Metabolic Stability Evaluation
Mohamed M. Alanazi, A. Obaidullah, M. Attwa
2022Molecules6 citations Open access
Semantic Scholar
Design, synthesis, and anticancer evaluation of spirooxindole-1,2,3-triazole hybrids as potent VEGFR-2 inhibitors.
A. Barakat, Moayad Abdullah Alwehaibi, A. Alayyaf, M. Ali +7 more
2025Bioorganic chemistry (Print)5 citations
Semantic Scholar
Phospholipid-based nano drug delivery system of curcumin using MSP1D1 protein and poloxamer 407: a comparative study for targeted drug delivery to the brain
M. H. Shariare, Mahbia Mannan, F. Khan, Ayesha Sharmin +5 more
2024Journal of nanoparticle research5 citations
Semantic Scholar
Effective quantification of ravidasvir (an NS5A inhibitor) and sofosbuvir in rat plasma by validated LC-MS/MS method and its application to pharmacokinetic study
Mohamed M. Hefnawy, S. Hammad, A. Kadi, Nawaf A. Alsaif +5 more
20205 citations Open access
Semantic Scholar
Evaluation of Anlotinib Metabolic Stability in HLMs Matrix Applying Ultra-Fast UPLC-MS/MS Approach: Greenness Assessment With In Silico Testing for Structural Alarms Related to the Metabolic Lability and DEREK Toxicity.
M. Attwa, A. Abdelhameed, A. Kadi
2025Biomedical chromotography4 citations
Semantic Scholar
An Ultrafast UPLC–MS/MS Method for Characterizing the In Vitro Metabolic Stability of Acalabrutinib
M. Attwa, A. Bakheit, A. Abdelhameed, A. Kadi
2023Molecules4 citations Open access
Semantic Scholar
Evaluation of Alectinib Metabolic Stability in HLMs Using Fast LC-MS/MS Method: In Silico ADME Profile, P450 Metabolic Lability, and Toxic Alerts Screening
M. Attwa, H. Alrabiah, G. A. Mostafa, A. Kadi
2023Pharmaceutics4 citations Open access
Semantic Scholar
Profiling of in vivo, in vitro and reactive zorifertinib metabolites using liquid chromatography ion trap mass spectrometry
Nasser S Al-Shakliah, A. Kadi, Haya I. Aljohar, H. Alrabiah +1 more
2022RSC Advances4 citations Open access
Semantic Scholar
Simvastatin: In Vitro Metabolic Profiling of a Potent Competitive HMG-CoA Reductase Inhibitor
Wencui Yin, Reem I. Alwabli, M. Attwa, A. M. Motiur Rahman +1 more
2022Separations4 citations Open access
Semantic Scholar

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A. Kadi×31
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A. Kadi — researcher profile on SciRah
A. Abdelhameed×18
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A. Abdelhameed — researcher profile on SciRah
H. Alrabiah×15
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H. Alrabiah — researcher profile on SciRah
A. Bakheit×6
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A. Bakheit — researcher profile on SciRah

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H. Darwish — researcher profile on SciRah

Nasser S Al-Shakliah×6

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G. A. Mostafa×6

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G. A. Mostafa — researcher profile on SciRah

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H. Ghabbour — researcher profile on SciRah

Aishah M. Alsibaee×3

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Aishah M. Alsibaee — researcher profile on SciRah

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A. Alanazi — researcher profile on SciRah

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E. Elzayat — researcher profile on SciRah

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