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J. Chlebek · SciRah

Researcher profile · Semantic Scholar

J. Chlebek

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J. Chlebek — researcher profile on SciRah

h-index: 20
Works: 49
Citations: 856

Most-cited papers

Amaryllidaceae alkaloids from Narcissus pseudonarcissus L. cv. Dutch Master as potential drugs in treatment of Alzheimer's disease.
D. Hulcová, J. Maříková, J. Korábečný, A. Hošťálková +9 more
2019Phytochemistry52 citations Open access
Semantic Scholar
Tannins and their Influence on Health
K. Macáková, V. Kolečkář, L. Cahlíková, J. Chlebek +4 more
201450 citations
Semantic Scholar
Cytotoxic activities of Amaryllidaceae alkaloids against gastrointestinal cancer cells
Ivo Doskočil, A. Hošťálková, M. Safratova, N. Benešová +6 more
201544 citations
Semantic Scholar
Multi-target neuroprotective effects of herbal medicines for Alzheimer's disease.
Filipe Fernandes, Fátima Barroso, A. De Simone, Eliška Emriková +8 more
2022Journal of Ethnopharmacology41 citations Open access
Semantic Scholar
Acetylcholinesterase and Butyrylcholinesterase Inhibitory Compounds from Corydalis Cava (Fumariaceae)
J. Chlebek, K. Macáková, L. Cahlíková, Milan Kurfürst +2 more
2011Natural Product Communications40 citations Open access
Semantic Scholar
Alkaloids from Narcissus poeticus cv. Pink Parasol of various structural types and their biological activity
M. Safratova, A. Hošťálková, D. Hulcová, K. Breiterová +13 more
2017Archives of pharmacal research39 citations
Semantic Scholar
Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment.
L. Zemanová, J. Hofman, E. Novotná, K. Musílek +6 more
2015Journal of Natural Products37 citations Open access
Semantic Scholar
Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targets.
J. Chlebek, A. De Simone, A. Hošťálková, L. Opletal +5 more
2016Fitoterapia36 citations Open access
Semantic Scholar
Isoquinoline Alkaloids from Fumaria officinalis L. and Their Biological Activities Related to Alzheimer's Disease
J. Chlebek, Zdeněk Novák, Dominika Kassemová, M. Safratova +16 more
2016Chemistry and Biodiversity34 citations
Semantic Scholar
Isoquinoline alkaloids as a novel type of AKR1C3 inhibitors.
Lucie Škarydová, J. Hofman, J. Chlebek, J. Havránková +6 more
2014Journal of Steroid Biochemistry and Molecular Biology31 citations
Semantic Scholar
Acetylcholinesterase and Butyrylcholinesterase Inhibitory Compounds from Eschscholzia californica (Papaveraceae)
L. Cahlíková, K. Macáková, J. Kuneš, Milan Kurfürst +4 more
2010Natural Product Communications31 citations Open access
Semantic Scholar
In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier
J. Chlebek, J. Korábečný, R. Doležal, Šárka Štěpánková +8 more
2019Molecules30 citations Open access
Semantic Scholar
Scoulerine affects microtubule structure, inhibits proliferation, arrests cell cycle and thus culminates in the apoptotic death of cancer cells
K. Habartová, R. Havelek, M. Seifrtová, K. Královec +8 more
2018Scientific Reports29 citations Open access
Semantic Scholar
Alkaloids from Chlidanthus fragrans and their Acetylcholinesterase, Butyrylcholinesterase and Prolyl Oligopeptidase Activities
L. Cahlíková, M. Hrabinová, A. Kulhánková, N. Benešová +7 more
2013Natural Product Communications29 citations Open access
Semantic Scholar
Isoquinoline alkaloids as prolyl oligopeptidase inhibitors.
L. Cahlíková, Lucie Hulová, M. Hrabinová, J. Chlebek +7 more
2015Fitoterapia27 citations
Semantic Scholar
Isolation of Amaryllidaceae alkaloids from Nerine bowdenii W. Watson and their biological activities
N. Vaněčková, Anna Hošt'álková, M. Safratova, J. Kuneš +9 more
201626 citations
Semantic Scholar
In Vitro Inhibitory Effects of 8-O-Demethylmaritidine and Undulatine on Acetylcholinesterase and Their Predicted Penetration across the Blood-Brain Barrier.
L. Cahlíková, Daniel I. Perez, Šárka Štěpánková, J. Chlebek +3 more
2015Journal of Natural Products25 citations Open access
Semantic Scholar
Cholinesterase and Prolyl Oligopeptidase Inhibitory Activities of Alkaloids from Argemone platyceras (Papaveraceae)
T. Siatka, Markéta Adamcová, L. Opletal, L. Cahlíková +4 more
2017Molecules24 citations Open access
Semantic Scholar
Ecdysterone and its Activity on some Degenerative Diseases
L. Cahlíková, K. Macáková, J. Chlebek, Anna Hošt'álková +2 more
2011Natural Product Communications22 citations Open access
Semantic Scholar
Alkaloids of Zephyranthes citrina (Amaryllidaceae) and their implication to Alzheimer's disease: Isolation, structural elucidation and biological activity.
Eliška Kohelová, J. Maříková, J. Korábečný, D. Hulcová +14 more
2020Bioorganic chemistry (Print)21 citations
Semantic Scholar
Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease.
R. Vrabec, J. Maříková, M. Ločárek, J. Korábečný +14 more
2021Phytochemistry20 citations Open access
Semantic Scholar
Hand Gesture Interface for Robot Path Definition in Collaborative Applications: Implementation and Comparative Study
Aleš Vysocký, Tomáš Poštulka, J. Chlebek, T. Kot +2 more
2023Italian National Conference on Sensors19 citations Open access
Semantic Scholar
Natural Products as Potential Human Ether-A-Go-Go-Related Gene Channel Inhibitors – Screening of Plant-Derived Alkaloids
Anja Schramm, P. Saxena, J. Chlebek, L. Cahlíková +3 more
2014Planta Medica18 citations
Semantic Scholar
Alkaloids from Peumus boldus and their Acetylcholinesterase, Butyrylcholinesterase and Prolyl Oligopeptidase Inhibition Activity
Anna Hošt'álková, L. Opletal, J. Kuneš, Zdeněk Novák +4 more
2015Natural Product Communications14 citations Open access
Semantic Scholar
Isolation and Cholinesterase Inhibitory Activity of Narcissus Extracts and Amaryllidaceae Alkaloid
L. Cahlíková, M. Ločárek, N. Benešová, R. Kučera +3 more
201313 citations Open access
Semantic Scholar
Interactions of Isoquinoline Alkaloids with Transition Metals Iron and Copper
Mst Shamima Parvin, J. Chlebek, A. Hošťálková, M. C. Catapano +3 more
2022Molecules12 citations Open access
Semantic Scholar
Corylucinine, a new Alkaloid from Corydalis cava (Fumariaceae), and its Cholinesterase Activity
Zdeněk Novák, J. Chlebek, L. Opletal, P. Jiroš +3 more
2012Natural Product Communications12 citations Open access
Semantic Scholar
The anticancer properties of harmine and its derivatives
Abdul Aziz Timbilla, R. Vrabec, R. Havelek, M. Řezáčová +3 more
2024Phytochemistry Reviews11 citations Open access
Semantic Scholar
Alkaloids of Dicranostigma franchetianum (Papaveraceae) and Berberine Derivatives as a New Class of Antimycobacterial Agents
Viriyanata Wijaya, O. Jand́ourek, J. Křoustková, Kateřina Hradiská-Breiterová +11 more
2022Biomolecules11 citations Open access
Semantic Scholar
Antimicrobial Activity of Extracts and Isoquinoline Alkaloids of Selected Papaveraceae Plants
L. Opletal, M. Ločárek, Adéla Fraňková, J. Chlebek +7 more
2014Natural Product Communications10 citations Open access
Semantic Scholar
Natural Compounds (Small Molecules) as Potential and Real Drugs of Alzheimer's Disease
L. Cahlíková, K. Macáková, N. Benešová, J. Chlebek +2 more
201410 citations
Semantic Scholar
Can Isoquinoline Alkaloids Affect Platelet Aggregation in Whole Human Blood?
M. Parvin, M. Hrubša, Jaka Fadraersada, A. Carazo +5 more
2022Toxins7 citations Open access
Semantic Scholar
Amaryllidaceae Alkaloids from Clivia miniata (Lindl.) Bosse (Amaryllidaceae): Isolation, Structural Elucidation, and Biological Activity
M. Safratova, J. Křoustková, N. Maafi, Daniela Suchánková +6 more
2022Plants7 citations Open access
Semantic Scholar
Pharmacognosy and Its Role in the System of Profile Disciplines in Pharmacy
L. Cahlíková, M. Safratova, A. Hošťálková, J. Chlebek +3 more
20207 citations Open access
Semantic Scholar
Cytotoxicity of Naturally Occurring Isoquinoline Alkaloids of Different Structural Types
J. Chlebek, Ivo Doskočil, D. Hulcová, K. Breiterová +6 more
2016Natural Product Communications7 citations Open access
Semantic Scholar
HaDR: Applying Domain Randomization for Generating Synthetic Multimodal Dataset for Hand Instance Segmentation in Cluttered Industrial Environments
Stefan Grushko, Aleš Vysocký, J. Chlebek, Petr Prokop
2023Applied Informatics5 citations Open access
Semantic Scholar
Recent Advances in Medicinal Chemistry
Atta-ur-Rahman, M. Choudhary, George Perry, Amalia Bosia +59 more
20172 citations
Semantic Scholar
Proanthocyanidins and their antioxidation activity [Proanthocyanidiny a jejich antioxidační aktivita]
V. Kolečkář, Z. Řeháková, E. Brojerová, K. Kuča +7 more
20122 citations
Semantic Scholar
Protozoan Neglected Tropical Diseases (NTDs) Target Inhibition of Alkaloids from Croton linearis Jacq Leaves: A Molecular Docking and ADMET Approach
J. Rojas-Vargas, Jesús García-Díaz, J. Escalona-Arranz, J. Chlebek +3 more
2025Pharmaceuticals1 citations Open access
Semantic Scholar
Anticoronavirus Isoquinoline Alkaloids: Unraveling the Secrets of Their Structure–Activity Relationship
M. Safratova, Yu-Li Chen, Anna Hošťálková, J. Chlebek +8 more
2025Influenza and Other Respiratory Viruses1 citations Open access
Semantic Scholar
Undescribed Amaryllidaceae Alkaloids from Zephyranthes citrina and Their Cytotoxicity
J. Křoustková, Eliška Kohelová, D. Muthná, Jiří Kuneš +8 more
2024Journal of Natural Products1 citations Open access
Semantic Scholar
Boldine alkaloids and prospects of their utilization
A. Hošťálková, T. Siatka, J. Chlebek, L. Opletal +2 more
20151 citations
Semantic Scholar
Harmine Derivatives as Anticancer Agents Endowed With Potent and Selective Antileukemia Activity: Synthesis, Biological Evaluation, Proapoptotic and Genotoxic Activity
Abdul Aziz Timbilla, Filip Pidaný, Eliška Kohelová, J. Křoustková +14 more
2026Archiv der Pharmazie0 citations Open access
Semantic Scholar
Isolation and biological activity of alkaloids from Vinca minor L. related to Alzheimerʼs disease
R. Vrabec, J. Křoustková, M. Ločárek, D. Hulcová +15 more
2022GA – 70th Annual Meeting 20220 citations
Semantic Scholar
Scoulerine affects microtubule structure, inhibits proliferation, arrests cell cycle and thus culminates in the apoptotic death of cancer cells
K. Habartová, R. Havelek, M. Seifrtová, K. Královec +8 more
2018Scientific Reports0 citations Open access
Semantic Scholar
Multifunctional activity of some isoquinoline alkaloids from Corydalis cava tubers on Alzheimer's disease targets
J. Chlebek, A. de Simone, Daniel I. Perez, Concepción Pérez +5 more
2016Planta Medica0 citations
Semantic Scholar
Cytotoxic potential of naturally occurring isoquinoline alkaloids possessing different structural types
Lucie Cahlíková, Ivo Doskočil, J. Chlebek, Anna Hošťálková +2 more
2016Planta Medica0 citations
Semantic Scholar
Antioxidanty a degenerativní onemocnění
Lubomír Opletal, J. Chlebek, Kateřina Mačáková, Nina Benešová +2 more
20130 citations
Semantic Scholar
Anticholinesterase and free-radical scavenging activity of Corydalis cava alkaloids
J. Chlebek, K. Macáková, L. Cahlíková, L. Opletal +2 more
20110 citations
Semantic Scholar

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