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E. Chiarpotto · SciRah

Researcher profile · Semantic Scholar

E. Chiarpotto

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E. Chiarpotto — researcher profile on SciRah

h-index: 33
Works: 84
Citations: 4,016

Most-cited papers

Oxidative stress and cell signalling.
G. Poli, G. Leonarduzzi, F. Biasi, E. Chiarpotto
2004Current Medicinal Chemistry742 citations
Semantic Scholar
The lipid peroxidation end product 4‐hydroxy‐2,3‐nonenal up‐regulates transforming growth factor β1 expression in the macrophage lineage: a link between oxidative injury and fibrosclerosis 1
G. Leonarduzzi, A. Scavazza, F. Biasi, E. Chiarpotto +4 more
1997The FASEB Journal277 citations
Semantic Scholar
Autophagic degradation contributes to muscle wasting in cancer cachexia.
F. Penna, D. Costamagna, F. Pin, Andrea Camperi +6 more
2013American Journal of Pathology269 citations Open access
Semantic Scholar
Lipid oxidation products in cell signaling.
G. Leonarduzzi, M. C. Arkan, H. Basaga, E. Chiarpotto +2 more
2000Free Radical Biology & Medicine218 citations
Semantic Scholar
Nuclear factor kB is activated by arachidonic acid but not by eicosapentaenoic acid.
S. Camandola, G. Leonarduzzi, T. Musso, L. Varesio +5 more
1996Biochemical and Biophysical Research Communications - BBRC194 citations
Semantic Scholar
Calorie restriction and dietary restriction mimetics: a strategy for improving healthy aging and longevity.
G. Testa, F. Biasi, G. Poli, E. Chiarpotto
2014Current pharmaceutical design154 citations
Semantic Scholar
4-Hydroxynonenal and cholesterol oxidation products in atherosclerosis.
G. Leonarduzzi, E. Chiarpotto, F. Biasi, G. Poli
2005Molecular Nutrition & Food Research148 citations
Semantic Scholar
Alternate-day fasting protects the rat heart against age-induced inflammation and fibrosis by inhibiting oxidative damage and NF-kB activation.
L. Castello, T. Froio, Marco Maina, G. Cavallini +6 more
2010Free Radical Biology & Medicine109 citations
Semantic Scholar
Oxysterol mixtures prevent proapoptotic effects of 7‐ ketocholesterol in macrophages: implications for proatherogenic gene modulation
F. Biasi, G. Leonarduzzi, B. Vizio, D. Zanetti +6 more
2004The FASEB Journal101 citations
Semantic Scholar
Reperfusion damage to the bile canaliculi in transplanted human liver
J. Cutrin, Dario Cantino, F. Biasi, E. Chiarpotto +7 more
1996Hepatology99 citations Open access
Semantic Scholar
Regulation of rat hepatocyte protein kinase C β isoenzymes by the lipid peroxidation product 4‐hydroxy‐2,3‐nonenal: A signaling pathway to modulate vesicular transport of glycoproteins
E. Chiarpotto, C. Domenicotti, D. Paola, A. Vitali +9 more
1999Hepatology95 citations Open access
Semantic Scholar
Early Involvement of ROS Overproduction in Apoptosis Induced by 7-Ketocholesterol
G. Leonarduzzi, B. Vizio, B. Sottero, V. Verde +5 more
2006Antioxidants and Redox Signaling93 citations
Semantic Scholar
Oxysterol-induced up-regulation of MCP-1 expression and synthesis in macrophage cells.
G. Leonarduzzi, P. Gamba, B. Sottero, A. Kadl +7 more
2005Free Radical Biology & Medicine84 citations
Semantic Scholar
Associated changes of lipid peroxidation and transforming growth factor β1 levels in human colon cancer during tumour progression
F. Biasi, L. Tessitore, D. Zanetti, J. Cutrin +5 more
2002Gut81 citations Open access
Semantic Scholar
Proinflammatory effect of cholesterol and its oxidation products on CaCo-2 human enterocyte-like cells: effective protection by epigallocatechin-3-gallate.
C. Mascia, Marco Maina, E. Chiarpotto, G. Leonarduzzi +2 more
2010Free Radical Biology & Medicine75 citations
Semantic Scholar
Pro-oxidant and proapoptotic effects of cholesterol oxidation products on human colonic epithelial cells: a potential mechanism of inflammatory bowel disease progression.
F. Biasi, C. Mascia, M. Astegiano, E. Chiarpotto +4 more
2009Free Radical Biology & Medicine75 citations
Semantic Scholar
Up‐regulation of the fibrogenic cytokine TGF‐β1 by oxysterols: a mechanistic link between cholesterol and atherosclerosis
G. Leonarduzzi, A. Sevanian, B. Sottero, M. C. Arkan +4 more
2001The FASEB Journal71 citations
Semantic Scholar
Biogenic 4‐hydroxy‐2‐nonenal activates transcription factor AP‐1 but not NF‐κB in cells of the macrophage lineage
S. Camandola, Antonella Scavazza, G. Leonarduzzi, F. Biasi +3 more
1997Biofactors65 citations
Semantic Scholar
Calorie restriction protects against age‐related rat aorta sclerosis
L. Castello, T. Froio, G. Cavallini, F. Biasi +5 more
2005The FASEB Journal59 citations
Semantic Scholar
Oxidative damage in human liver transplantation.
F. Biasi, M. Bosco, I. Chiappino, E. Chiarpotto +6 more
1995Free Radical Biology & Medicine58 citations
Semantic Scholar
Glutathione depletion induces apoptosis of rat hepatocytes through activation of protein kinase C novel isoforms and dependent increase in AP-1 nuclear binding.
C. Domenicotti, D. Paola, Antonella Vitali, M. Nitti +8 more
2000Free Radical Biology & Medicine57 citations
Semantic Scholar
In vivo and in vitro evidence concerning the role of lipid peroxidation in the mechanism of hepatocyte death due to carbon tetrachloride
F. Biasi, E. Albano, E. Chiarpotto, F. Corongiu +5 more
1991Cell Biochemistry and Function57 citations
Semantic Scholar
c-Jun N-terminal kinase upregulation as a key event in the proapoptotic interaction between transforming growth factor-beta1 and 4-hydroxynonenal in colon mucosa.
F. Biasi, B. Vizio, C. Mascia, E. Gaia +4 more
2006Free Radical Biology & Medicine55 citations
Semantic Scholar
4-hydroxynonenal and transforming growth factor-beta1 expression in colon cancer.
D. Zanetti, G. Poli, B. Vizio, B. Zingaro +2 more
2003Molecular Aspects of Medicine54 citations
Semantic Scholar
Lipid peroxidation in human diseases: evidence of red cell oxidative stress after circulatory shock.
G. Poli, F. Biasi, E. Chiarpotto, M. U. Dianzani +2 more
1989Free Radical Biology & Medicine51 citations
Semantic Scholar
Plaque oxysterols induce unbalanced up-regulation of matrix metalloproteinase-9 in macrophagic cells through redox-sensitive signaling pathways: Implications regarding the vulnerability of atherosclerotic lesions.
Simona Gargiulo, B. Sottero, P. Gamba, E. Chiarpotto +2 more
2011Free Radical Biology & Medicine48 citations
Semantic Scholar
Oxidative damage and transforming growth factor beta 1 expression in pretumoral and tumoral lesions of human intestine.
E. Chiarpotto, Antonella Scavazza, G. Leonarduzzi, S. Camandola +6 more
1997Free Radical Biology & Medicine45 citations
Semantic Scholar
Phenolic compounds present in Sardinian wine extracts protect against the production of inflammatory cytokines induced by oxysterols in CaCo-2 human enterocyte-like cells.
F. Biasi, T. Guina, Marco Maina, B. Cabboi +12 more
2013Biochemical Pharmacology43 citations Open access
Semantic Scholar
Lipid peroxidation and covalent binding in the early functional impairment of liver golgi apparatus by carbon tetrachloride
G. Poli, D. Cottalasso, M. Pronzato, E. Chiarpotto +5 more
1990Cell Biochemistry and Function41 citations
Semantic Scholar
Evidence of cell damage induced by major components of a diet-compatible mixture of oxysterols in human colon cancer CaCo-2 cell line.
F. Biasi, E. Chiarpotto, B. Sottero, Marco Maina +7 more
2013Biochimie40 citations Open access
Semantic Scholar
Oxidation as a crucial reaction for cholesterol to induce tissue degeneration: CD36 overexpression in human promonocytic cells treated with a biologically relevant oxysterol mixture
G. Leonarduzzi, P. Gamba, Simona Gargiulo, B. Sottero +7 more
2008Aging Cell39 citations
Semantic Scholar
Trojan horse-like behavior of a biologically representative mixture of oxysterols.
G. Poli, G. Leonarduzzi, B. Vizio, E. Chiarpotto +1 more
2004Molecular Aspects of Medicine35 citations
Semantic Scholar
Liver AP-1 activation due to carbon tetrachloride is potentiated by 1,2-dibromoethane but is inhibited by alpha-tocopherol or gadolinium chloride.
S. Camandola, M. Aragno, J. Cutrin, E. Tamagno +6 more
1999Free Radical Biology & Medicine33 citations Open access
Semantic Scholar
Alternate-day fasting reverses the age-associated hypertrophy phenotype in rat heart by influencing the ERK and PI3K signaling pathways.
L. Castello, Marco Maina, G. Testa, G. Cavallini +6 more
2011Mechanisms of Ageing and Development32 citations
Semantic Scholar
4-Hydroxynonenal signalling to apoptosis in isolated rat hepatocytes: the role of PKC-delta.
L. Castello, B. Marengo, M. Nitti, T. Froio +7 more
2005Biochimica et Biophysica Acta30 citations
Semantic Scholar
Oxidative stress in the development of human ischemic hepatitis during circulatory shock.
F. Biasi, E. Chiarpotto, G. Lanfranco, A. Capra +5 more
1994Free Radical Biology & Medicine29 citations
Semantic Scholar
Promethazine inhibits the formation of aldehydic products of lipid peroxidation but not covalent binding resulting from the exposure of rat liver fractions to CCl4.
G. Poli, K. Cheeseman, F. Biasi, E. Chiarpotto +3 more
1989Biochemical Journal26 citations Open access
Semantic Scholar
Lipid peroxidation and irreversible cell damage: synergism between carbon tetrachloride and 1,2-dibromoethane in isolated rat hepatocytes.
O. Danni, E. Chiarpotto, Manuela Aragno, F. Biasi +4 more
1991Toxicology and Applied Pharmacology24 citations
Semantic Scholar
Role of 4‐hydroxy‐2,3‐nonenal in the pathogenesis of fibrosis
E. Chiarpotto, L. Castello, G. Leonarduzzi, F. Biasi +1 more
2005Biofactors23 citations
Semantic Scholar
4‐Hydroxynonenal and TGF‐β1 concur in inducing antiproliferative effects on the Caco‐2 human colon adenocarcinoma cell line
B. Vizio, G. Poli, E. Chiarpotto, F. Biasi
2005Biofactors20 citations
Semantic Scholar
Metabolism of 4-hydroxy-2-nonenal and aging.
E. Chiarpotto, F. Biasi, Antonella Scavazza, S. Camandola +2 more
1995Biochemical and Biophysical Research Communications - BBRC18 citations
Semantic Scholar
Inactivation of hepatocyte protein kinase C by carbon tetrachloride: involvement of drug's metabolic activation and prooxidant effect.
M. Pronzato, C. Domenicotti, F. Biasi, E. Chiarpotto +5 more
1990Biochemical and Biophysical Research Communications - BBRC17 citations
Semantic Scholar
CCl4-induced increase of hepatocyte free arachidonate level: pathogenesis and contribution to cell death.
E. Chiarpotto, F. Biasi, A. Comoglio, G. Leonarduzzi +2 more
1990Chemico-Biological Interactions15 citations
Semantic Scholar
Molecular mechanisms of calorie restriction's protection against age‐related sclerosis
E. Chiarpotto, E. Bergamini, G. Poli
2006IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology13 citations Open access
Semantic Scholar
Acetaldehyde involvement in ethanol-induced potentiation of rat hepatocyte damage due to the carcinogen 1,2-dibromoethane.
E. Chiarpotto, F. Biasi, Antonella Scavazza, S. Camandola +5 more
1995Alcohol and Alcoholism13 citations
Semantic Scholar
Electron spin resonance studies on isolated hepatocytes treated with ferrous or ferric iron.
G. Poli, E. Albano, A. Tomasi, K. Cheeseman +5 more
1987Free Radical Research Communications13 citations
Semantic Scholar
Induction of cytochrome(s) P450‐dependent drug metabolism in cultured MH1C1 hepatoma cells
M. Ferro, A. Bassi, U. Marinari, G. Nanni +3 more
1984Cell Biochemistry and Function13 citations
Semantic Scholar
In vitro evidence for CCl4 metabolites covalently bound to lipoprotein micelles
G. Poli, E. Albano, F. Biasi, E. Chiarpotto +1 more
1983FEBS Letters13 citations Open access
Semantic Scholar
The core‐aldehyde 9‐oxononanoyl cholesterol increases the level of transforming growth factor β1‐specific receptors on promonocytic U937 cell membranes
Simona Gargiulo, P. Gamba, B. Sottero, F. Biasi +5 more
2009Aging Cell10 citations
Semantic Scholar
In vivo potentiation of 1,2-dibromoethane hepatotoxicity by ethanol through inactivation of glutathione-s-transferase.
M. Aragno, E. Tamagno, O. Danni, E. Chiarpotto +5 more
1996Chemico-Biological Interactions9 citations
Semantic Scholar

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F. Biasi×43
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F. Biasi — researcher profile on SciRah
G. Poli×42
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G. Leonarduzzi×27
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M. U. Dianzani×11
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B. Vizio — researcher profile on SciRah

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U. Marinari — researcher profile on SciRah

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P. Gamba — researcher profile on SciRah

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M. Pronzato — researcher profile on SciRah

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L. Castello — researcher profile on SciRah

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Marco Maina — researcher profile on SciRah