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F. Sironi · SciRah

Researcher profile · Semantic Scholar

F. Sironi

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F. Sironi — researcher profile on SciRah

h-index: 27
Works: 56
Citations: 2,260

Most-cited papers

Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival
S. Dispinseri, M. Secchi, M. Pirillo, M. Tolazzi +16 more
2021Nature Communications347 citations Open access
Semantic Scholar
The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson’s disease and originates from a common ancestor
S. Goldwurm, A. Di Fonzo, Erik J. Simons, C. Rohé +26 more
2005Journal of Medical Genetics199 citations Open access
Semantic Scholar
Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes
Loïc Martin, F. Stricher, D. Missé, F. Sironi +10 more
2003Nature Biotechnology180 citations
Semantic Scholar
Alpha-defensins block the early steps of HIV-1 infection: interference with the binding of gp120 to CD4.
L. Furci, F. Sironi, M. Tolazzi, L. Vassena +1 more
2007Blood115 citations Open access
Semantic Scholar
LRRK2 G2019S mutation and Parkinson's disease: a clinical, neuropsychological and neuropsychiatric study in a large Italian sample.
S. Goldwurm, M. Zini, A. di Fonzo, D. De Gaspari +18 more
2006Parkinsonism & Related Disorders110 citations
Semantic Scholar
Evaluation of LRRK2 G2019S penetrance
S. Goldwurm, M. Zini, L. Mariani, S. Tesei +5 more
2007Neurology96 citations
Semantic Scholar
Cryptic Nature of a Conserved, CD4-Inducible V3 Loop Neutralization Epitope in the Native Envelope Glycoprotein Oligomer of CCR5-Restricted, but Not CXCR4-Using, Primary Human Immunodeficiency Virus Type 1 Strains
P. Lusso, P. Earl, F. Sironi, F. Santoro +5 more
2005Journal of Virology93 citations Open access
Semantic Scholar
Kin‐cohort analysis of LRRK2‐G2019S penetrance in Parkinson's disease
S. Goldwurm, S. Tunesi, S. Tesei, M. Zini +4 more
2011Movement Disorders61 citations
Semantic Scholar
Long-term follow-up of patients with Bartter syndrome type I and II.
E. Puricelli, A. Bettinelli, N. Borsa, F. Sironi +4 more
2010Nephrology, Dialysis and Transplantation61 citations Open access
Semantic Scholar
SNCA and MAPT genes: Independent and joint effects in Parkinson disease in the Italian population
L. Trotta, I. Guella, G. Soldà, F. Sironi +6 more
2012Parkinsonism & Related Disorders53 citations Open access
Semantic Scholar
Structural determinants of CCR5 recognition and HIV-1 blockade in RANTES
V. Nardese, R. Longhi, S. Polo, F. Sironi +8 more
2001Nature Structural Biology53 citations
Semantic Scholar
Parkin analysis in early onset Parkinson's disease.
F. Sironi, P. Primignani, M. Zini, S. Tunesi +19 more
2008Parkinsonism & Related Disorders51 citations
Semantic Scholar
Enhancement of the HIV‐1 inhibitory activity of RANTES by modification of the N‐terminal region: dissociation from CCR5 activation
S. Polo, V. Nardese, C. de Santis, C. Arcelloni +6 more
2000European Journal of Immunology50 citations Open access
Semantic Scholar
RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue
Antonio Vallarola, F. Sironi, M. Tortarolo, Noemi Gatto +9 more
2018Journal of Neuroinflammation47 citations Open access
Semantic Scholar
The 5-HT1B receptor mediates the effect of d-fenfluramine on eating caused by intra-hypothalamic injection of neuropeptide Y.
Giuliano Grignaschi, F. Sironi, Rosario Samanin
1995European Journal of Pharmacology46 citations
Semantic Scholar
Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer
Peng Zhang, J. Gorman, Hui Geng, Qing-Bo Liu +23 more
2018Cell Host and Microbe43 citations Open access
Semantic Scholar
Stimulation of 5-HT2A receptors in the paraventricular hypothalamus attenuates neuropeptide Y-induced hyperphagia through activation of corticotropin releasing factor.
G. Grignaschi, F. Sironi, R. Samanin
1996Brain Research43 citations
Semantic Scholar
Inhibition of HIV-1 Infection by Human α-Defensin-5, a Natural Antimicrobial Peptide Expressed in the Genital and Intestinal Mucosae
L. Furci, M. Tolazzi, F. Sironi, L. Vassena +1 more
2012PLoS ONE41 citations Open access
Semantic Scholar
alpha-Synuclein multiplication analysis in Italian familial Parkinson disease.
F. Sironi, L. Trotta, A. Antonini, M. Zini +9 more
2010Parkinsonism & Related Disorders41 citations
Semantic Scholar
Multiple intracerebroventricular injections of human umbilical cord mesenchymal stem cells delay motor neurons loss but not disease progression of SOD1G93A mice.
F. Sironi, Antonio Vallarola, M. Violatto, L. Talamini +9 more
2017Stem Cell Research37 citations Open access
Semantic Scholar
Inhibition of CXCR4-Tropic HIV-1 Infection by Lipopolysaccharide: Evidence of Different Mechanisms in Macrophages and T Lymphocytes1
Alessia Verani, F. Sironi, A. Siccardi, P. Lusso +1 more
2002Journal of Immunology37 citations Open access
Semantic Scholar
A novel dominant missense mutation – D179N – in the GJB2 gene (Connexin 26) associated with non‐syndromic hearing loss
P. Primignani, P. Castorina, F. Sironi, C. Curcio +2 more
2003Clinical Genetics36 citations
Semantic Scholar
An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD
C. Bauer, Rebecca Cohen, F. Sironi, M. Livesey +10 more
2022Acta Neuropathologica33 citations Open access
Semantic Scholar
Analysis of the GJB2 and GJB6 Genes in Italian Patients with Nonsyndromic Hearing Loss: Frequencies, Novel Mutations, Genotypes, and Degree of Hearing Loss
P. Primignani, L. Trotta, P. Castorina, F. Lalatta +13 more
2009Genetic Testing and Molecular Biomarkers31 citations
Semantic Scholar
CXCL13/CXCR5 signalling is pivotal to preserve motor neurons in amyotrophic lateral sclerosis
M. C. Trolese, A. Mariani, M. Terao, M. De Paola +10 more
2020EBioMedicine29 citations Open access
Semantic Scholar
Effect of RNS60 in amyotrophic lateral sclerosis: a phase II multicentre, randomized, double‐blind, placebo‐controlled trial
E. Beghi, E. Pupillo, E. Bianchi, V. Bonetto +110 more
2022European Journal of Neurology28 citations Open access
Semantic Scholar
Mutational screening and zebrafish functional analysis of GIGYF2 as a Parkinson-disease gene.
I. Guella, A. Pistocchi, R. Asselta, V. Rimoldi +11 more
2009Neurobiology of Aging27 citations
Semantic Scholar
Screening LRRK2 gene mutations in patients with Parkinson’s disease in Ghana
R. Cilia, F. Sironi, A. Akpalu, M. Cham +6 more
2012Journal of Neurology26 citations
Semantic Scholar
Activating Killer Immunoglobulin Receptors and HLA-C: a successful combination providing HIV-1 control
M. Malnati, E. Ugolotti, M. Monti, D. De Battista +17 more
2017Scientific Reports25 citations Open access
Semantic Scholar
HFE gene mutations in a population of Italian Parkinson's disease patients.
G. Biasiotto, S. Goldwurm, D. Finazzi, S. Tunesi +4 more
2008Parkinsonism & Related Disorders25 citations
Semantic Scholar
Boosting the peripheral immune response in the skeletal muscles improved motor function in ALS transgenic mice
M. C. Trolese, C. Scarpa, Valentina Melfi, Paola Fabbrizio +4 more
2021Molecular Therapy24 citations Open access
Semantic Scholar
Analysis of ferritin genes in Parkinson disease.
B. Foglieni, F. Ferrari, S. Goldwurm, P. Santambrogio +15 more
2007Clinical Chemistry and Laboratory Medicine23 citations
Semantic Scholar
Molecular engineering of RANTES peptide mimetics with potent anti‐HIV‐1 activity
P. Lusso, L. Vangelista, R. Cimbro, M. Secchi +5 more
2011The FASEB Journal22 citations Open access
Semantic Scholar
Novel P2X7 Antagonist Ameliorates the Early Phase of ALS Disease and Decreases Inflammation and Autophagy in SOD1-G93A Mouse Model
S. Apolloni, Paola Fabbrizio, Susanna Amadio, Giulia Napoli +7 more
2021International Journal of Molecular Sciences19 citations Open access
Semantic Scholar
HIV-1 Env associates with HLA-C free-chains at the cell membrane modulating viral infectivity
M. Serena, F. Parolini, P. Biswas, F. Sironi +11 more
2017Scientific Reports18 citations Open access
Semantic Scholar
DJ1 analysis in a large cohort of Italian early onset Parkinson Disease patients
F. Sironi, P. Primignani, Sara Ricca, S. Tunesi +6 more
2013Neuroscience Letters15 citations Open access
Semantic Scholar
Critical role of the N-loop and beta1-strand hydrophobic clusters of RANTES-derived peptides in anti-HIV activity.
L. Vangelista, R. Longhi, F. Sironi, V. Pavone +1 more
2006Biochemical and Biophysical Research Communications - BBRC14 citations Open access
Semantic Scholar
Correction for Parolini et al., “Stability and Expression Levels of HLA-C on the Cell Membrane Modulate HIV-1 Infectivity”
F. Parolini, P. Biswas, M. Serena, F. Sironi +11 more
2018Journal of Virology13 citations Open access
Semantic Scholar
Enhancement of anti-HIV-1 activity by hot spot evolution of RANTES-derived peptides.
M. Secchi, R. Longhi, L. Vassena, F. Sironi +3 more
2012Chemistry and Biology12 citations Open access
Semantic Scholar
First‐trimester prenatal screening for the common 35delG GJB2 mutation causing prelingual deafness
D. Coviello, B. Brambati, L. Tului, A. Percesepe +4 more
2004Prenatal Diagnosis8 citations Open access
Semantic Scholar
Broad-Spectrum Inhibition of HIV-1 by a Monoclonal Antibody Directed against a gp120-Induced Epitope of CD4
S. Burastero, B. Frigerio, L. Lopalco, F. Sironi +6 more
2011PLoS ONE7 citations Open access
Semantic Scholar
Stability and Expression Levels of HLA-C on the Cell Membrane Modulate HIV-1 Infectivity
F. Parolini, Priscilla Biswas, M. Serena, F. Sironi +11 more
2017Journal of Virology6 citations Open access
Semantic Scholar
The longitudinal characterization of immune responses in COVID-19 patients reveals novel prognostic signatures for disease severity, patients’ survival and long COVID
M. Noviello, R. De Lorenzo, Raniero Chimienti, N. Maugeri +32 more
2024Frontiers in Immunology5 citations Open access
Semantic Scholar
Characterization of HIV-1 entry inhibitors with broad activity against R5 and X4 viral strains
F. Sironi, M. Malnati, N. Mongelli, P. Cozzi +7 more
2015Journal of Translational Medicine4 citations Open access
Semantic Scholar
A fast and reliable method for detecting SNP rs67384697 (Hsa-miR-148a binding site) by a single run of allele-specific real-time PCR.
M. Malnati, P. Biswas, E. Ugolotti, E. di Marco +6 more
2020HLA2 citations
Semantic Scholar
An improved method for HLA-B and -C supratyping.
Roberto Biassoni, M. Malnati, I. Vanni, A. Raso +8 more
2015JIM - Journal of Immunological Methods2 citations
Semantic Scholar
COVID-BioB Cohort Study: the neutralizing antibody response to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for virus control and survival.
S. Dispinseri, M. Secchi, M. Pirillo, M. Tolazzi +16 more
2021medRxiv1 citations Open access
Semantic Scholar
Corrigendum: HIV-1 Env associates with HLA-C free-chains at the cell membrane modulating viral infectivity
M. Serena, F. Parolini, P. Biswas, F. Sironi +11 more
2018Scientific Reports1 citations Open access
Semantic Scholar
P-C21 Molecular Mimicry of a Helical Region in Domain 1 of CD4 Facilitates Interdomain Stabilization of HIV-1 gp120
B. Dey, Peng Zhang, C. Guzzi, P. Lusso +9 more
20171 citations Open access
Semantic Scholar
Comment on "compound heterozygosity in DJ-1 gene non-coding portion related to Parkinsonism".
F. Sironi, P. Primignani, S. Goldwurm
2010Parkinsonism & Related Disorders1 citations
Semantic Scholar

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