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S. Eldfors · SciRah

Researcher profile · Semantic Scholar

S. Eldfors

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S. Eldfors — researcher profile on SciRah

h-index: 24
Works: 109
Citations: 3,889

Most-cited papers

Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia
H. Koskela, S. Eldfors, P. Ellonen, A. V. van Adrichem +25 more
2012New England Journal of Medicine860 citations Open access
Semantic Scholar
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia.
H. Rajala, S. Eldfors, H. Kuusanmäki, A. V. van Adrichem +16 more
2013Blood393 citations Open access
Semantic Scholar
Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia.
T. Pemovska, M. Kontro, B. Yadav, H. Edgren +32 more
2013Cancer Discovery393 citations
Semantic Scholar
Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3.
E. Haapaniemi, Meri Kaustio, H. Rajala, A. V. van Adrichem +23 more
2015Blood262 citations Open access
Semantic Scholar
Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia
D. Malani, Ashwini Kumar, O. Brück, M. Kontro +23 more
2021Cancer Discovery157 citations Open access
Semantic Scholar
Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target
O. Dufva, M. Kankainen, T. Kelkka, N. Sekiguchi +23 more
2018Nature Communications134 citations Open access
Semantic Scholar
Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia
H. Kuusanmäki, O. Dufva, M. Vähä-Koskela, Aino-Maija Leppä +25 more
2022Blood117 citations Open access
Semantic Scholar
Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis
P. Savola, Tiina Kelkka, H. Rajala, Antti Kuuliala +15 more
2017Nature Communications112 citations Open access
Semantic Scholar
Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia
M. Kontro, H. Kuusanmäki, S. Eldfors, T. Burmeister +19 more
2014Leukemia99 citations
Semantic Scholar
Comprehensive Drug Testing of Patient-derived Conditionally Reprogrammed Cells from Castration-resistant Prostate Cancer.
K. Saeed, V. Rahkama, S. Eldfors, D. Bychkov +13 more
2017European Urology92 citations Open access
Semantic Scholar
Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling
E. Andersson, S. Pützer, B. Yadav, O. Dufva +35 more
2017Leukemia91 citations
Semantic Scholar
High incidence of activating STAT5B mutations in CD4-positive T-cell large granular lymphocyte leukemia.
E. Andersson, Takahiro Tanahashi, N. Sekiguchi, V. R. Gasparini +20 more
2016Blood90 citations Open access
Semantic Scholar
HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia
M. Kontro, A. Kumar, M. Majumder, S. Eldfors +13 more
2017Leukemia75 citations Open access
Semantic Scholar
Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation
E. Andersson, H. Rajala, S. Eldfors, P. Ellonen +9 more
2013Blood Cancer Journal67 citations Open access
Semantic Scholar
Activating somatic mutations outside the SH2-domain of STAT3 in LGL-Leukemia
E. Andersson, H. Kuusanmäki, S. Bortoluzzi, S. Lagström +12 more
2015Leukemia64 citations Open access
Semantic Scholar
Mutation accumulation in cancer genes relates to nonoptimal outcome in chronic myeloid leukemia.
Shady Adnan Awad, M. Kankainen, Teija Ojala, P. Koskenvesa +8 more
2020Blood Advances62 citations Open access
Semantic Scholar
Dasatinib and navitoclax act synergistically to target NUP98-NSD1+/FLT3-ITD+ acute myeloid leukemia
Jarno Kivioja, A. Thanasopoulou, Ashwini Kumar, M. Kontro +7 more
2018Leukemia56 citations
Semantic Scholar
Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia
S. Eldfors, H. Kuusanmäki, M. Kontro, M. Majumder +9 more
2016Leukemia56 citations Open access
Semantic Scholar
Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML
D. Malani, A. Murumägi, B. Yadav, M. Kontro +12 more
2016Leukemia55 citations Open access
Semantic Scholar
Identification of precision treatment strategies for relapsed/refractory multiple myeloma by functional drug sensitivity testing
M. Majumder, R. Silvennoinen, P. Anttila, D. Tamborero +10 more
2017OncoTarget40 citations Open access
Semantic Scholar
Epidemiological, clinical and molecular characterization of Lynch‐like syndrome: A population‐based study
Noora Porkka, L. Lahtinen, M. Ahtiainen, J. Böhm +5 more
2019International Journal of Cancer38 citations Open access
Semantic Scholar
Converging endometrial and ovarian tumorigenesis in Lynch syndrome: Shared origin of synchronous carcinomas.
Anni Niskakoski, Annukka Pasanen, Noora Porkka, S. Eldfors +6 more
2018Gynecologic Oncology38 citations Open access
Semantic Scholar
Clonal heterogeneity influences drug responsiveness in renal cancer assessed by ex vivo drug testing of multiple patient‐derived cancer cells
K. Saeed, P. Ojamies, T. Pellinen, S. Eldfors +10 more
2018International Journal of Cancer38 citations Open access
Semantic Scholar
Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease
Daehong Kim, Giljun Park, Jani Huuhtanen, S. Lundgren +19 more
2020Nature Communications23 citations Open access
Semantic Scholar
Sequencing of Lynch syndrome tumors reveals the importance of epigenetic alterations
Noora Porkka, Satu Valo, T. Nieminen, A. Olkinuora +3 more
2017OncoTarget21 citations Open access
Semantic Scholar
Somatic mutations and T-cell clonality in patients with immunodeficiency
P. Savola, T. Martelius, M. Kankainen, Jani Huuhtanen +12 more
2019Haematologica20 citations Open access
Semantic Scholar
Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature
T. Kelkka, P. Savola, Dipabarna Bhattacharya, Jani Huuhtanen +19 more
2020Frontiers in Immunology18 citations Open access
Semantic Scholar
Monitoring therapy responses at the leukemic subclone level by ultra-deep amplicon resequencing in acute myeloid leukemia
P. Ojamies, M. Kontro, H. Edgren, P. Ellonen +10 more
2016Leukemia17 citations
Semantic Scholar
Monosomy 7/del(7q) cause sensitivity to inhibitors of nicotinamide phosphoribosyltransferase in acute myeloid leukemia
S. Eldfors, J. Saad, N. Ikonen, Disha Malani +5 more
2023medRxiv14 citations Open access
Semantic Scholar
Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas
Noora Porkka, A. Olkinuora, T. Kuopio, M. Ahtiainen +4 more
2020OncoTarget13 citations Open access
Semantic Scholar
Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer
Sara Kangaspeska, S. Hultsch, A. Jaiswal, H. Edgren +5 more
2016BMC Cancer13 citations Open access
Semantic Scholar
Novel TBL1XR1, EPHA7 and SLFN12 mutations in a Sezary syndrome patient discovered by whole exome sequencing
E. Andersson, S. Eldfors, H. Edgren, P. Ellonen +3 more
2014Experimental Dermatology13 citations Open access
Semantic Scholar
Molecular Basis of Mismatch Repair Protein Deficiency in Tumors from Lynch Suspected Cases with Negative Germline Test Results
A. Olkinuora, A. Gylling, H. Almusa, S. Eldfors +4 more
2020Cancers10 citations Open access
Semantic Scholar
Rad51c- and Trp53-double-mutant mouse model reveals common features of homologous recombination-deficient breast cancers
M. Tumiati, P. Munne, H. Edgren, S. Eldfors +2 more
2016Oncogene5 citations
Semantic Scholar
Abstract 2945: Clinical implementation of precision systems oncology in the treatment of ovarian cancer based on ex-vivo drug testing and molecular profiling
A. Murumägi, D. Ungureanu, S. Khan, A. Hirasawa +15 more
2019Experimental and Molecular Therapeutics4 citations
Semantic Scholar
Novel Activating STAT5B Mutations As Drivers Of T-ALL
H. Kuusanmäki, S. Eldfors, T. Pemovska, H. Rajala +8 more
20134 citations
Semantic Scholar
Discovery of STAT5b Mutations and Small Subclones of STAT3 Mutations in Large Granular Lymphocytic (LGL) Leukemia
H. Rajala, S. Eldfors, H. Kuusanmäki, E. Andersson +16 more
20124 citations
Semantic Scholar
Whole exome sequencing and single-cell DNA sequencing for assessment of clonal heterogeneity and evolution in acute myeloid leukemia
Sadiksha Adhikari, S. Eldfors, E. Pitkänen, M. Vähä-Koskela +1 more
2025bioRxiv3 citations Open access
Semantic Scholar
Predictive Response Biomarkers for BET Inhibitors in AML
J. Saad, Juho J Miettinen, D. Tsallos, S. Eldfors +6 more
2018Blood3 citations Open access
Semantic Scholar
High-Throughput Ex Vivo Drug Sensitivity and Resistance Testing (DSRT) Integrated with Deep Genomic and Molecular Profiling Reveal New Therapy Options with Targeted Drugs in Subgroups of Relapsed Chemorefractory AML
C. Heckman, M. Kontro, T. Pemovska, S. Eldfors +24 more
20123 citations
Semantic Scholar
ATR/CHK1/WEE1 Dependency in SRSF2-Mutated MDS/AML
S. Eldfors, Sumit Rai, Vineet Sharma, Angelique Gilbert +2 more
2021Blood2 citations
Semantic Scholar
Corrigendum: Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature
T. Kelkka, P. Savola, Dipabarna Bhattacharya, Jani Huuhtanen +19 more
2021Frontiers in Immunology2 citations Open access
Semantic Scholar
A phase 2 study of carfilzomib plus elotuzumab plus dexamethasone for myeloma patients relapsed after 1-3 prior treatment lines
R. Silvennoinen, D. Tsallos, H. Nahi, P. Anttila +17 more
2018Clinical Lymphoma, Myeloma & Leukemia2 citations
Semantic Scholar
Abstract 2378: Responses of AML patients to tailored drug regimens: monitoring cancer subclones by ultra-deep resequencing
P. Ojamies, M. Kontro, H. Edgren, P. Ellonen +10 more
20162 citations
Semantic Scholar
Abstract 3175: Genomic and transcriptomic data integration in chronic myelomonocytic leukemia reveals a novel fusion gene involving onco-miR-125b-2
M. Majumder, M. Kontro, H. Edgren, D. Nicorici +16 more
2012Molecular and Cellular Biology2 citations
Semantic Scholar
Whole Genome HPV Liquid Biopsy for Pan-HPV-Associated Cancer Detection and Viral Physical State Classification
A. S. Fisch, A. Abruzzo, S. Eldfors, D. Das +13 more
2026medRxiv1 citations Open access
Semantic Scholar
Circulating Tumor HPV DNA Kinetics for Squamous Cell Carcinoma of the Lacrimal Sac Treated with Chemoradiotherapy
J. Paly, W. Faquin, R. Merkin, Shriya Shukla +5 more
2026Head and Neck Pathology1 citations
Semantic Scholar
Liquid Biopsy of HPV Cell-Free DNA Enables Blood-Based Early Detection and Molecular Stratification of HPV-Associated Cancer and Precancer Stages
Qin Wang, S. Eldfors, S. Lee, D. Das +13 more
2026medRxiv1 citations Open access
Semantic Scholar
Multi-omic and functional screening reveal targetable vulnerabilities in TP53 mutated multiple myeloma
D. Tsallos, N. Ikonen, J. Miettinen, M. Majumder +12 more
2024medRxiv1 citations Open access
Semantic Scholar
3067 – ATR/CHK1/WEE1 DEPENDENCY IN SRSF2-MUTATED MDS/AML
S. Eldfors, Sumit Rai, Vineet Sharma, Tareq Hossan +6 more
2024Experimental Hematology1 citations Open access
Semantic Scholar

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O. Kallioniemi×14

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