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W. Syn · SciRah

Researcher profile · Semantic Scholar

W. Syn

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W. Syn — researcher profile on SciRah

h-index: 50
Works: 164
Citations: 8,297

Most-cited papers

Extrahepatic complications of nonalcoholic fatty liver disease
M. J. Armstrong, L. Adams, A. Canbay, W. Syn
2014Hepatology368 citations Open access
Semantic Scholar
Osteopontin Mediates an MZF1-TGF-β1-Dependent Transformation of Mesenchymal Stem Cells into Cancer Associated Fibroblasts in Breast Cancer
Cynthia E. Weber, A. Kothari, Philip Y. Wai, Neill Y. Li +10 more
2014Oncogene223 citations Open access
Semantic Scholar
Vitamin D counteracts fibrogenic TGF-β signalling in human hepatic stellate cells both receptor-dependently and independently
A. Beilfuss, J. Sowa, S. Sydor, M. Beste +9 more
2014Gut154 citations
Semantic Scholar
Randomized Placebo-Controlled Trial of Emricasan in Non-alcoholic Steatohepatitis (NASH) Cirrhosis with Severe Portal Hypertension.
G. Garcia-Tsao, J. Bosch, Z. Kayali, S. Harrison +71 more
2019Journal of Hepatology140 citations Open access
Semantic Scholar
Hedgehog regulates Yes-associated protein 1 in regenerating mouse liver
M. Swiderska-syn, G. Xie, G. Michelotti, M. Jewell +3 more
2016Hepatology122 citations Open access
Semantic Scholar
Osteopontin—A Master Regulator of Epithelial-Mesenchymal Transition
A. Kothari, M. Arffa, V. Chang, R. Blackwell +4 more
2016Journal of Clinical Medicine112 citations Open access
Semantic Scholar
Hepatokines and adipokines in NASH-related hepatocellular carcinoma.
O. Kucukoglu, J. Sowa, G. Mazzolini, W. Syn +1 more
2020Journal of Hepatology107 citations Open access
Semantic Scholar
Hepatitis E Virus Infection as a Possible Cause of Acute Liver Failure in Europe.
P. Manka, L. Bechmann, J. Coombes, V. Thodou +9 more
2015Clinical Gastroenterology and Hepatology104 citations Open access
Semantic Scholar
Role of Metabolism in Hepatic Stellate Cell Activation and Fibrogenesis
W. Hou, W. Syn
2018Front. Cell Dev. Biol.103 citations Open access
Semantic Scholar
Serum Interleukin‐8, Osteopontin, and Monocyte Chemoattractant Protein 1 Are Associated With Hepatic Fibrosis in Patients With Nonalcoholic Fatty Liver Disease
O. Glass, Ricardo Henao, K. Patel, Cynthia D. Guy +7 more
2018Hepatology Communications94 citations Open access
Semantic Scholar
Human intrahepatic regulatory T cells are functional, require IL‐2 from effector cells for survival, and are susceptible to Fas ligand‐mediated apoptosis
Yung-Yi Chen, H. Jeffery, S. Hunter, R. Bhogal +13 more
2016Hepatology85 citations Open access
Semantic Scholar
Periodontitis is associated with significant hepatic fibrosis in patients with non-alcoholic fatty liver disease
W. Alazawi, E. Bernabé, David Tai, T. Janicki +5 more
2017PLoS ONE84 citations Open access
Semantic Scholar
Methotrexate Hepatotoxicity and the Impact of Nonalcoholic Fatty Liver Disease.
A. Shetty, WonKyung Cho, W. Alazawi, W. Syn
2017American Journal of the Medical Sciences73 citations
Semantic Scholar
Fibrosis in Chronic Liver Disease: An Update on Diagnostic and Treatment Modalities
P. Manka, A. Zeller, W. Syn
2019Drugs72 citations Open access
Semantic Scholar
Role of the Circadian Clock in the Metabolic Syndrome and Nonalcoholic Fatty Liver Disease
A. Shetty, J. Hsu, P. Manka, W. Syn
2018Digestive Diseases and Sciences68 citations Open access
Semantic Scholar
TWEAK/Fn14 Signaling Is Required for Liver Regeneration after Partial Hepatectomy in Mice
G. Karaca, M. Swiderska-syn, G. Xie, W. Syn +8 more
2014PLoS ONE63 citations Open access
Semantic Scholar
Fetuin-A mRNA expression is elevated in NASH compared with NAFL patients.
A. Kahraman, J. Sowa, M. Schlattjan, S. Sydor +9 more
2013Clinical science57 citations
Semantic Scholar
Osteopontin is a proximal effector of leptin-mediated non-alcoholic steatohepatitis (NASH) fibrosis
J. Coombes, Steve S. Choi, M. Swiderska-syn, P. Manka +19 more
2015Biochimica et Biophysica Acta56 citations Open access
Semantic Scholar
Low Free Triiodothyronine Is Associated with Advanced Fibrosis in Patients at High Risk for Nonalcoholic Steatohepatitis
P. Manka, L. Bechmann, J. Best, S. Sydor +7 more
2019Digestive Diseases and Sciences52 citations
Semantic Scholar
Endoscopic management is the treatment of choice for bile leaks after liver resection.
A. Dechêne, C. Jochum, C. Fingas, A. Paul +5 more
2014Gastrointestinal Endoscopy51 citations
Semantic Scholar
Significance of Simple Steatosis: An Update on the Clinical and Molecular Evidence
G. Mazzolini, J. Sowa, Catalina Atorrasagasti, Özlem Kücükoglu +2 more
2020Cells50 citations Open access
Semantic Scholar
Iron Enhances Hepatic Fibrogenesis and Activates Transforming Growth Factor‐&bgr; Signaling in Murine Hepatic Stellate Cells
K. Mehta, J. Coombes, M. Briones-Orta, P. Manka +3 more
2017American Journal of the Medical Sciences50 citations Open access
Semantic Scholar
Epigallocatechin-3-Gallate Upregulates miR-221 to Inhibit Osteopontin-Dependent Hepatic Fibrosis
M. Arffa, M. Zapf, A. Kothari, V. Chang +7 more
2016PLoS ONE44 citations Open access
Semantic Scholar
Health and Economic Burden of Nonalcoholic Fatty Liver Disease in the United States and Its Impact on Veterans.
A. Shetty, W. Syn
2019Federal practitioner : for the health care professionals of the VA, DoD, and PHS40 citations
Semantic Scholar
Role of liver progenitors in liver regeneration.
J. Best, P. Manka, W. Syn, L. Dollé +2 more
2015Hepatobiliary surgery and nutrition40 citations
Semantic Scholar
Amitriptyline Inhibits Nonalcoholic Steatohepatitis and Atherosclerosis Induced by High-Fat Diet and LPS through Modulation of Sphingolipid Metabolism.
Zhong-Yang Lu, Yanchun Li, W. Syn, Zhe-Wu Wang +3 more
2019American Journal of Physiology. Endocrinology and Metabolism39 citations Open access
Semantic Scholar
Low Levels of Blood Lipids Are Associated with Etiology and Lethal Outcome in Acute Liver Failure
P. Manka, Verena Olliges, L. Bechmann, M. Schlattjan +6 more
2014PLoS ONE33 citations Open access
Semantic Scholar
Proteomic screening of plasma identifies potential noninvasive biomarkers associated with significant/advanced fibrosis in patients with nonalcoholic fatty liver disease
W. Hou, Michael G. Janech, P. Sobolesky, A. Bland +3 more
2019Bioscience Reports32 citations Open access
Semantic Scholar
Non-invasive markers of liver fibrosis in fatty liver disease are unreliable in people of South Asian descent
S. de Silva, Wen-Hao Li, P. Kemos, J. Brindley +7 more
2017Frontline Gastroenterology32 citations Open access
Semantic Scholar
Galectin-3, histone deacetylases, and Hedgehog signaling: Possible convergent targets in schistosomiasis-induced liver fibrosis
F. L. de Oliveira, K. Carneiro, J. Brito, M. Cabanel +5 more
2017PLoS Neglected Tropical Diseases32 citations Open access
Semantic Scholar
The motor protein Myo1c regulates transforming growth factor-β-signaling and fibrosis in podocytes
Ehtesham Arif, Ashish Kumar Solanki, Pankaj Srivastava, Bushra Rahman +13 more
2019Kidney International31 citations Open access
Semantic Scholar
Osteopontin regulates the cross-talk between phosphatidylcholine and cholesterol metabolism in mouse liver[S]
Maitane Núñez-García, Beatriz Gómez-Santos, Xabier Buqué, J. L. García-Rodríguez +8 more
2017Journal of Lipid Research31 citations Open access
Semantic Scholar
NASH Cirrhosis - the New Burden in Liver Transplantation: How Should It Be Managed?
A. Canbay, J. Sowa, W. Syn, J. Treckmann
2016Visceral Medicine31 citations Open access
Semantic Scholar
Macrophage Depletion Attenuates Extracellular Matrix Deposition and Ductular Reaction in a Mouse Model of Chronic Cholangiopathies
J. Best, S. Verhulst, W. Syn, Kimberly Lagaisse +9 more
2016PLoS ONE29 citations Open access
Semantic Scholar
Liver osteopontin is required to prevent the progression of age‐related nonalcoholic fatty liver disease
Beatriz Gómez-Santos, Diego Sáenz de Urturi, Maitane Núñez-García, Francisco González-Romero +16 more
2020Aging Cell28 citations Open access
Semantic Scholar
Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni
T. Pereira, W. Syn, M. Machado, P. Vidigal +15 more
2015Clinical science28 citations Open access
Semantic Scholar
Mini-Laparoscopy Guided Liver Biopsy Increases Diagnostic Accuracy in Acute Liver Failure
A. Dechêne, J. Sowa, M. Schlattjan, A. Wree +8 more
2014Digestion28 citations
Semantic Scholar
Non-nutritive sweeteners and their association with the metabolic syndrome and non-alcoholic fatty liver disease: a review of the literature
Caitlin H. Green, W. Syn
2019European Journal of Nutrition26 citations
Semantic Scholar
Diagnostic Accuracy of Non-Imaging and Ultrasound-Based Assessment of Hepatic Steatosis Using Controlled Attenuation Parameter (CAP) as Reference
K. Kozłowska-Petriczko, E. Wunsch, J. Petriczko, W. Syn +1 more
2021Journal of Clinical Medicine22 citations Open access
Semantic Scholar
GPR40-Deficiency Is Associated with Hepatic FAT/CD36 Upregulation, Steatosis, Inflammation and Cell Injury in C57BL/6 Mice.
Zhong-Yang Lu, Yanchun Li, W. Syn, Ai-jun Li +4 more
2020American Journal of Physiology. Endocrinology and Metabolism21 citations Open access
Semantic Scholar
Phosphorylation and Stabilization of PIN1 by JNK Promote Intrahepatic Cholangiocarcinoma Growth
Alessio Lepore, Pui Man Choy, Nathan Lee, Maria Annunziata Carella +12 more
2021Hepatology18 citations Open access
Semantic Scholar
A Review of the Epidemiology, Pathophysiology, and Efficacy of Anti-diabetic Drugs Used in the Treatment of Nonalcoholic Fatty Liver Disease
P. Manka, Kaya Eda, A. Canbay, W. Syn
2021Digestive Diseases and Sciences18 citations Open access
Semantic Scholar
Higher Thyroid-Stimulating Hormone, Triiodothyronine and Thyroxine Values Are Associated with Better Outcome in Acute Liver Failure
O. Anastasiou, S. Sydor, J. Sowa, P. Manka +8 more
2015PLoS ONE18 citations Open access
Semantic Scholar
Osteopontin is up-regulated in chronic hepatitis C and is associated with cellular permissiveness for hepatitis C virus replication
Steve S. Choi, Lee C. Claridge, Ravi R. Jhaveri, M. Swiderska-syn +10 more
2014Clinical science18 citations Open access
Semantic Scholar
Current treatment options for nonalcoholic fatty liver disease
A. Shetty, W. Syn
2019Current Opinion in Gastroenterology15 citations
Semantic Scholar
Practical approach to non‐alcoholic fatty liver disease in patients with diabetes
F.-W.-D. Tai, W. Syn, W. Alazawi
2015Diabetic Medicine15 citations
Semantic Scholar
Characteristics of amino acid substitutions within the "a" determinant region of hepatitis B virus in chronically infected patients with coexisting HBsAg and anti-HBs.
W. Hou, Zhi-Xiao Huo, Yanan Du, Cindy Wang +1 more
2020Clinics And Research in Hepatology and Gastroenterology12 citations
Semantic Scholar
Osteopontin Is Upregulated in Human and Murine Acute Schistosomiasis Mansoni
T. Pereira, W. Syn, F. Amâncio, Pedro Henrique Diniz Cunha +10 more
2016PLoS Neglected Tropical Diseases12 citations Open access
Semantic Scholar
Anti‐TNFα treatment in Crohn’s disease: Impact on hepatic steatosis, gut‐derived hormones and metabolic status
P. Manka, S. Sydor, Nishikant Wase, J. Best +21 more
2021Liver international (Print)11 citations Open access
Semantic Scholar
Serum osteopontin is a biomarker of severe fibrosis and portal hypertension in human and murine schistosomiasis mansoni
T. Pereira, W. Syn, F. E. Pereira, J. Lambertucci +2 more
2016International Journal of Parasitology11 citations Open access
Semantic Scholar

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