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Z. Kayali · SciRah

Researcher profile · Semantic Scholar

Z. Kayali

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Z. Kayali — researcher profile on SciRah

h-index: 22
Works: 59
Citations: 4,752

Most-cited papers

Sofosbuvir for previously untreated chronic hepatitis C infection.
E. Lawitz, A. Mangia, D. Wyles, M. Rodríguez-Torres +20 more
2013New England Journal of Medicine1,910 citations
Semantic Scholar
Cilofexor, a Nonsteroidal FXR Agonist, in Patients With Noncirrhotic NASH: A Phase 2 Randomized Controlled Trial
K. Patel, S. Harrison, M. Elkhashab, J. Trotter +20 more
2020Hepatology305 citations
Semantic Scholar
GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients with Nonalcoholic Fatty Liver Disease
R. Loomba, Z. Kayali, M. Noureddin, P. Ruane +14 more
2018Gastroenterology297 citations Open access
Semantic Scholar
A randomized, placebo-controlled trial of emricasan in patients with NASH and F1-F3 fibrosis.
S. Harrison, Z. Goodman, A. Jabbar, R. Vemulapalli +16 more
2019Journal of Hepatology226 citations
Semantic Scholar
Avatrombopag Before Procedures Reduces Need for Platelet Transfusion in Patients With Chronic Liver Disease and Thrombocytopenia.
N. Terrault, Yi-Cheng Chen, N. Izumi, Z. Kayali +4 more
2018Gastroenterology225 citations Open access
Semantic Scholar
Aramchol in patients with nonalcoholic steatohepatitis: a randomized, double-blind, placebo-controlled phase 2b trial
V. Ratziu, L. de Guevara, R. Safadi, F. Poordad +69 more
2021Nature Medicine208 citations Open access
Semantic Scholar
Safety and efficacy of combination therapy with semaglutide, cilofexor and firsocostat in patients with non-alcoholic steatohepatitis: A randomised, open-label phase II trial.
N. Alkhouri, R. Herring, Heidi Kabler, Z. Kayali +12 more
2022Journal of Hepatology206 citations Open access
Semantic Scholar
Hepatitis C, cryoglobulinemia, and cirrhosis: A meta‐analysis
Z. Kayali, Victor E. Buckwold, B. Zimmerman, W. Schmidt
2002Hepatology185 citations Open access
Semantic Scholar
The safety and efficacy of high‐dose proton beam radiotherapy for hepatocellular carcinoma: a phase 2 prospective trial
D. Bush, Z. Kayali, R. Grove, J. Slater
2011Cancer181 citations Open access
Semantic Scholar
Lusutrombopag for the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Undergoing Invasive Procedures (L‐PLUS 2)
M. Peck-Radosavljevic, K. Simon, A. Iacobellis, T. Hassanein +15 more
2019Hepatology145 citations Open access
Semantic Scholar
Randomized Placebo-Controlled Trial of Emricasan in Non-alcoholic Steatohepatitis (NASH) Cirrhosis with Severe Portal Hypertension.
G. Garcia-Tsao, J. Bosch, Z. Kayali, S. Harrison +71 more
2019Journal of Hepatology140 citations Open access
Semantic Scholar
EDP-305 in patients with NASH: A phase II double-blind placebo-controlled dose-ranging study.
V. Ratziu, M. Rinella, B. Neuschwander-Tetri, E. Lawitz +10 more
2021Journal of Hepatology107 citations Open access
Semantic Scholar
Volixibat in adults with non-alcoholic steatohepatitis: 24-week interim analysis from a randomized, phase II study.
P. Newsome, M. Palmer, B. Freilich, M. Sheikh +8 more
2020Journal of Hepatology73 citations Open access
Semantic Scholar
Emricasan to prevent new decompensation in patients with NASH-related decompensated cirrhosis.
C. Frenette, Z. Kayali, E. Mena, P. Mantry +11 more
2020Journal of Hepatology54 citations
Semantic Scholar
Pharmacogenomics and Personalized Medicine Dovepress Finally Sofosbuvir: an Oral Anti-hcv Drug with Wide Performance Capability
Z. Kayali, W. Schmidt, N. Schmidt
49 citations
Semantic Scholar
Variability and Lability of Ammonia Levels in Healthy Volunteers and Patients With Cirrhosis: Implications for Trial Design and Clinical Practice
J. Bajaj, P. Bloom, R. Chung, T. Hassanein +13 more
2019American Journal of Gastroenterology47 citations Open access
Semantic Scholar
Hemosiderosis is associated with accelerated decompensation and decreased survival in patients with cirrhosis
Z. Kayali, Rostislav D. Ranguelov, F. Mitros, C. Shufelt +4 more
2005Liver international (Print)34 citations
Semantic Scholar
Short‐duration treatment for chronic hepatitis C virus with daclatasvir, asunaprevir, beclabuvir and sofosbuvir (FOURward study)
M. Sulkowski, S. Flamm, Z. Kayali, E. Lawitz +7 more
2017Liver international (Print)32 citations
Semantic Scholar
Phase III (COSMIC-312) study of cabozantinib (C) in combination with atezolizumab (A) vs sorafenib (S) in patients (pts) with advanced hepatocellular carcinoma (aHCC) who have not received previous systemic anticancer therapy
T. Yau, L. Rimassa, A. Cheng, J.-W. Park +11 more
2019Annals of Oncology28 citations Open access
Semantic Scholar
Analysis of the intrahepatic ductular reaction and progenitor cell responses in hepatitis C virus recurrence after liver transplantation
E. Prakoso, Janina E. E. Tirnitz-Parker, Andrew D. Clouston, Z. Kayali +8 more
2014Liver transplantation28 citations Open access
Semantic Scholar
Increased plasma nitric oxide, L‐arginine, and arginase‐1 in cirrhotic patients with progressive renal dysfunction
Z. Kayali, J. Herring, P. Baron, E. Franco +11 more
2009Journal of Gastroenterology and Hepatology22 citations
Semantic Scholar
SOF/VEL/VOX for 8 or 12 weeks is well tolerated and results in high SVR12 rates in patients receiving opioid substitution therapy
J. Grebely, I. Jacobson, Z. Kayali, E. Verna +10 more
201720 citations
Semantic Scholar
Lower gastrointestinal bleeding secondary to Dieulafoy-like lesion of the rectum.
Z. Kayali, W. Sangchantr, B. Matsumoto
2000Journal of Clinical Gastroenterology18 citations
Semantic Scholar
Treatment of hepatitis C cryoglobulinemia: Mission and challenges
Z. Kayali, D. Labrecque, W. Schmidt
2006Current treatment options in gastroenterology14 citations
Semantic Scholar
A randomised, double‐blind, placebo‐controlled study of the LAG‐3‐depleting monoclonal antibody GSK2831781 in patients with active ulcerative colitis
G. D'Haens, L. Peyrin-Biroulet, D. Marks, Edoardo Lisi +10 more
2023Alimentary Pharmacology and Therapeutics12 citations Open access
Semantic Scholar
Differential effects of T-cell activation on gastric and small bowel permeability in alcohol-consuming mice.
Z. Alnadjim, Z. Kayali, Wael Haddad, E. Holmes +7 more
2002Alcoholism: Clinical and Experimental Research12 citations
Semantic Scholar
Integrated Safety and Efficacy Analyses of Phase 3 Trials of a Microbiome Therapeutic for Recurrent CDI
Colleen S. Kraft, Matthew Sims, Michael Silverman, T. Louie +205 more
2024Infectious Disease and Therapy8 citations Open access
Semantic Scholar
Superiority of Avatrombopag to Placebo in Increasing Platelet Counts in Patients with Chronic Liver Disease-Associated Thrombocytopenia Undergoing Scheduled Procedures: Results from 2, Phase 3 Randomized Studies
N. Terrault, D. Kuter, N. Izumi, Z. Kayali +3 more
20177 citations
Semantic Scholar
Phase 3 (COSMIC-312) study of cabozantinib in combination with atezolizumab vs sorafenib in patients with advanced hepatocellular carcinoma (aHCC) who have not received previous systemic anticancer therapy.
L. Rimassa, A. Cheng, F. Braiteh, F. Benzaghou +6 more
2019Annals of Oncology6 citations Open access
Semantic Scholar
EDP-305, a non-bile acid farnesoid X receptor (FXR) agonist, showed statistically significant improvements in liver biochemistry and hepatic steatosis in the phase 2a argon-1 study
V. Ratziu, M. Rinella, B. Tetri, E. Lawitz +11 more
2020Journal of Hepatology3 citations Open access
Semantic Scholar
Hepatic fibrosis is associated with histological activity in nonalcoholic steatohepatitis: an analysis from a large database of screening biopsies in the CENTAUR trial
V. Ratziu, V. Wong, N. Lanthier, J. Boursier +15 more
20173 citations
Semantic Scholar
A randomized, open-label, phase 2a study to assess the safety, pharmacodynamics, and pharmacokinetics of YAQ007 versus rifaximin in cirrhosis.
M. Ballester, J. Carbonell-Asins, A. El-Shabrawi, Darren Rubin +7 more
2026Hepatology2 citations
Semantic Scholar
LBP-24-Safety, tolerability and efficacy of volixibat, an apical sodium-dependent bile acid transporter inhibitor, in adults with nonalcoholic steatohepatitis: 24-week interim analysis results from a phase 2 study
P. Newsome, M. Palmer, B. Freilich, M. Sheikh +8 more
2019Journal of Hepatology2 citations
Semantic Scholar
Advances in Hepatitis C Treatment: At the Crossroads
Jerika T. Lam, Jason Yamaki, Z. Kayali
20152 citations Open access
Semantic Scholar
Acute Colonic Pseudo-obstruction (The Ogilvie syndrome): A Case Report and Review of Literature
N. Agarwal, Archana Mishra, Z. Kayali
20022 citations
Semantic Scholar
Characterization of changes in lipoprotein profiles of patients with nonalcoholic steatohepatitis treated with the acetyl-CoA carboxylase inhibitor GS-0976
P. Mantry, Z. Kayali, M. Noureddin, P. Ruane +13 more
20181 citations
Semantic Scholar
260 RANDOMIZED CONTROLLED TRIAL FOR PROTON BEAM RADIOTHERAPY VERSUS TRANSARTERIAL CHEMOEMBOLIZATION FOR THE TREATMENT OF HEPATOCELLULAR CARCINOMA; PRELIMINARY RESULTS
Z. Kayali, J. Slater, D. Bush
20131 citations Open access
Semantic Scholar
Crypt cell apoptosis and increased, mucosal permeability induced by activated T cells
Z. Alnadjim, Ronald K. Koehler, Z. Kayali, P. Efthimiou +7 more
19981 citations Open access
Semantic Scholar
Pharmacokinetics and Safety of a Single Dose of Brensocatib in Participants with Hepatic Impairment and Matched Participants with Normal Hepatic Functions
H. Usansky, S. Au Yeung, Sherry Li, T. Marbury +3 more
2026Clinical Pharmacokinetics0 citations Open access
Semantic Scholar
FRI-183 Ontamalimab reduces fibroinflammatory biomarkers and liver injury signals in metabolic dysfunction associated steatohepatitis
M. Noureddin, E. Lawitz, N. Alkhouri, M. Rudraraju +12 more
2026Journal of Hepatology0 citations
Semantic Scholar
SAT-209 Randomized, open-label, phase 2a comparator study to assess the pharmacodynamics, safety and pharmacokinetics of oral administration of mnk6106 (l-ornithine phenylacetate) vs. rifaximin in subjects with hepatic cirrhosis and a previous history of hepatic encephalopathy
Darren Rubin, Tarek Hassanein, P. Winkle, E. Lawitz +4 more
2025Journal of Hepatology0 citations
Semantic Scholar
Correction to: Integrated Safety and Efficacy Analyses of Phase 3 Trials of a Microbiome Therapeutic for Recurrent CDI
Colleen S. Kraft, Matthew Sims, Michael Silverman, T. Louie +205 more
2024Infectious Disease and Therapy0 citations Open access
Semantic Scholar
WED-294 The use of the FibroScan-AST score and AST to pre-identify metabolic dysfunction-associated steatohepatitis patients with active fibrogenesis in a Phase 1b open-label clinical trial
M. Noureddin, E. Lawitz, N. Alkhouri, Z. Kayali +27 more
2024Journal of Hepatology0 citations
Semantic Scholar
Su1554 INCIDENCE AND PREDICTORS OF 30-DAY READMISSIONS FOR SPONTANEOUS BACTERIAL PERITONITIS: AN ANALYSIS FROM THE NATIONAL READMISSION DATABASE
M. Salazar, Gianina Flocco, P. Argueta, A. Qureshi +3 more
2023Gastroenterology0 citations
Semantic Scholar
Sa1502 THE IMPACT OF MODERATE TO SEVERE PROTEIN CALORIE MALNUTRITION ON OUTCOMES AND HEALTHCARE RESOURCES UTILIZATION IN PATIENTS WITH ACUTE ALCOHOLIC HEPATITIS.
M. Salazar, Gianina Flocco, P. Argueta, Jamile' Wakim-Fleming +1 more
2023Gastroenterology0 citations
Semantic Scholar
OUTCOMES OF RAZOR BLADE INGESTION OF THE UPPER GASTROINTESTINAL TRACT IN AN INCARCERATED POPULATION
Trevor Dunbar, George B. Saffouri, Z. Kayali
2022Gastrointestinal Endoscopy0 citations
Semantic Scholar
Su1707 PROTEUS SYNDROME: A RARE CASE OF NON-CIRRHOTIC PORTAL HYPERTENSION MANIFESTING AS REFRACTORY ASCITES
S. Joseph, R. Makar, Daisy S. Lankarani, Z. Kayali
20200 citations
Semantic Scholar
SAT-298-MR elastography based fibrosis correlates with clinical liver events in patients with non-alcoholic fatty liver disease: A multi-center study
M. Han, J. Grotts, R. Saouaf, Nabil Noureddin +9 more
2019Journal of Hepatology0 citations
Semantic Scholar
THU-311-Liver enzymes cut offs in patients with advanced non-alcoholic fatty liver disease: A multi-center study
M. Han, R. Saouaf, Nabil Noureddin, J. Grotts +10 more
2019Journal of Hepatology0 citations
Semantic Scholar
Su1541 - Responsiveness of Controlled Attenuation Parameter (CAP) and Its Correlation with Magnetic Resonance Imagingproton Density Fat Fraction (MRI-PDFF) in a Multi-Center Clinical Trial of Subjects with Nonacoholic Steatohepatitis (NASH)
M. Noureddin, Z. Kayali, S. Harrison, P. Ruane +15 more
20180 citations
Semantic Scholar

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E. Lawitz×16
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E. Lawitz — researcher profile on SciRah
M. Noureddin×11
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M. Noureddin — researcher profile on SciRah
T. Hassanein×7
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T. Hassanein — researcher profile on SciRah
A. Sheikh×6
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A. Sheikh — researcher profile on SciRah

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B. Freilich — researcher profile on SciRah

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E. Mena — researcher profile on SciRah

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P. Mantry — researcher profile on SciRah

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R. Loomba — researcher profile on SciRah

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W. Schmidt — researcher profile on SciRah

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R. Herring — researcher profile on SciRah

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E. Harting — researcher profile on SciRah

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M. Rinella — researcher profile on SciRah