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P. Wes · SciRah

Researcher profile · Semantic Scholar

P. Wes

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P. Wes — researcher profile on SciRah

h-index: 21
Works: 32
Citations: 5,170

Most-cited papers

Transcriptomic analysis of purified human cortical microglia reveals age-associated changes
Thais F. Galatro, I. Holtman, A. Lerário, I. Vainchtein +15 more
2017Nature Neuroscience659 citations Open access
Semantic Scholar
TRPC1, a human homolog of a Drosophila store-operated channel.
P. Wes, J. Chevesich, A. Jeromin, C. Rosenberg +2 more
1995Proceedings of the National Academy of Sciences of the United States of America624 citations Open access
Semantic Scholar
Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
I. Holtman, D. D. A. Raj, Jeremy A. Miller, W. Schaafsma +9 more
2015Acta Neuropathologica Communications565 citations Open access
Semantic Scholar
Blocking Interleukin-1 Signaling Rescues Cognition, Attenuates Tau Pathology, and Restores Neuronal β-Catenin Pathway Function in an Alzheimer's Disease Model
M. Kitazawa, David Cheng, Michelle R. Tsukamoto, M. Koike +4 more
2011Journal of Immunology462 citations Open access
Semantic Scholar
Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease
Alexander J. Whitworth, D. Theodore, J. C. Greene, H. Beneš +2 more
2005Proceedings of the National Academy of Sciences of the United States of America418 citations Open access
Semantic Scholar
Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease.
Marc C. Meulener, Alexander J. Whitworth, Cecilia E. Armstrong-Gold, P. Rizzu +4 more
2005Current Biology357 citations Open access
Semantic Scholar
C. elegans odour discrimination requires asymmetric diversity in olfactory neurons
P. Wes, Cori Bargmann
2001Nature258 citations
Semantic Scholar
CX3CR1 Protein Signaling Modulates Microglial Activation and Protects against Plaque-independent Cognitive Deficits in a Mouse Model of Alzheimer Disease*
Seo-hyun Cho, Bing-Gui Sun, Yun-Gui Zhou, Tiina M. Kauppinen +4 more
2011Journal of Biological Chemistry256 citations Open access
Semantic Scholar
Targeting microglia for the treatment of Alzheimer's Disease
P. Wes, Faten A. Sayed, F. Bard, L. Gan
2016Glia209 citations
Semantic Scholar
Critical data‐based re‐evaluation of minocycline as a putative specific microglia inhibitor
Thomas Möller, F. Bard, A. Bhattacharya, K. Biber +11 more
2016Glia169 citations
Semantic Scholar
Induction of the Phase II Detoxification Pathway Suppresses Neuron Loss in Drosophila Models of Parkinson's Disease
K. Trịnh, K. Moore, P. Wes, P. Muchowski +3 more
2008Journal of Neuroscience156 citations Open access
Semantic Scholar
Next generation transcriptomics and genomics elucidate biological complexity of microglia in health and disease
P. Wes, I. Holtman, Erik W. G. M. Boddeke, Thomas Möller +1 more
2016Glia136 citations Open access
Semantic Scholar
Passive Immunization with Phospho-Tau Antibodies Reduces Tau Pathology and Functional Deficits in Two Distinct Mouse Tauopathy Models
S. Sankaranarayanan, D. Barten, L. Vana, N. Devidze +22 more
2015PLoS ONE135 citations Open access
Semantic Scholar
Termination of phototransduction requires binding of the NINAC myosin III and the PDZ protein INAD
P. Wes, Xianghua Xu, Hong‐Sheng Li, F. Chien +2 more
1999Nature Neuroscience128 citations
Semantic Scholar
Drosophila models pioneer a new approach to drug discovery for Parkinson's disease.
Alexander J. Whitworth, P. Wes, L. Pallanck
2006Drug Discovery Today115 citations
Semantic Scholar
Tau Overexpression Impacts a Neuroinflammation Gene Expression Network Perturbed in Alzheimer’s Disease
P. Wes, Amy E. Easton, John P. Corradi, D. Barten +16 more
2014PLoS ONE106 citations Open access
Semantic Scholar
Retinal Targets for Calmodulin Include Proteins Implicated in Synaptic Transmission*
Xianghua Xu, P. Wes, Hua Chen, Hong‐Sheng Li +4 more
1998Journal of Biological Chemistry103 citations Open access
Semantic Scholar
RIC, a calmodulin‐binding Ras‐like GTPase.
P. Wes, Mujun Yu, C. Montell
1996EMBO Journal93 citations Open access
Semantic Scholar
Tau Transgenic Mice as Models for Cerebrospinal Fluid Tau Biomarkers
D. Barten, G. Cadelina, N. Hoque, L. Decarr +8 more
2011Journal of Alzheimer's Disease91 citations
Semantic Scholar
Subchronic treatment with aldosterone induces depression-like behaviours and gene expression changes relevant to major depressive disorder.
N. Hlaváčová, P. Wes, Mária Ondrejcáková, Marianne E. Flynn +4 more
2012International Journal of Neuropsychopharmacology73 citations Open access
Semantic Scholar
Transcriptomic analysis of purified human cortical microglia reveals age-associated changes
Thais F. Galatro, I. Holtman, A. Lerário, I. Vainchtein +15 more
201731 citations
Semantic Scholar
Activated RIC, a small GTPase, genetically interacts with the Ras pathway and calmodulin during Drosophila development
Susan M. W. Harrison, Jennifer L. Rudolph, M. L. Spencer, P. Wes +3 more
2005Developmental Dynamics16 citations
Semantic Scholar
Quality of Research Tools.
D. Doller, P. Wes
2019Handbook of Experimental Pharmacology3 citations Open access
Semantic Scholar
Human USP18 protects diverse cancer lineages from Type I Interferon independently of its canonical catalytic function
Veronica Jové, Heather Wheeler, C. Lee, D. Healy +12 more
2023bioRxiv2 citations Open access
Semantic Scholar
Microglial Biology in Neuroinflammatory Disease: Pharmaco-industrial Approach to Target Validation
Thomas Möller, P. Wes, D. Doller
20142 citations
Semantic Scholar
Discovery of conformation-sensitive anti-amyloid protofibril monoclonal antibodies using an engineered chaperone-like amyloid-binding protein
W. V. Graham, A. Bonito-Oliva, Rita Agostinelli, Riyaz Karim +10 more
2019bioRxiv1 citations Open access
Semantic Scholar
Developing Topics.
P. Wes, Josip Butković, Ka-Leung Wong, Brian Hinger +5 more
2025Alzheimer's & Dementia0 citations Open access
Semantic Scholar
The Effects of MIMICing
P. Wes, A. L. Baylor
20120 citations
Semantic Scholar
Mouse Model of Alzheimer Disease Plaque-independent Cognitive Deficits in a Microglial Activation and Protects against CX 3 CR 1 Protein Signaling Modulates Molecular Bases of Disease :
Seo-hyun Cho, Bing-Gui Sun, Yun-Gui Zhou, Tiina M. Kauppinen +3 more
20110 citations
Semantic Scholar
P1‐105: Human neural progenitor cells as an in vitro model system to study mitochondrial dysfunction in Alzheimer's disease
A. Cacace, P. Wes, Marianne E. Flynn, Cathy Kieras +6 more
20100 citations Open access
Semantic Scholar
InductionofthePhaseIIDetoxificationPathwaySuppresses NeuronLossinDrosophilaModelsofParkinson'sDisease
P. Wes
20080 citations
Semantic Scholar
TRPC1,ahumanhomologofaDrosophila store-operated channel
P. Wes
19950 citations
Semantic Scholar

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