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L. Ottosson · SciRah

Researcher profile · Semantic Scholar

L. Ottosson

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L. Ottosson — researcher profile on SciRah

h-index: 20
Works: 51
Citations: 2,000

Most-cited papers

Redox Modification of Cysteine Residues Regulates the Cytokine Activity of High Mobility Group Box-1 (HMGB1)
Huan Yang, P. Lundbäck, L. Ottosson, H. Erlandsson-Harris +6 more
2012Molecular Medicine439 citations Open access
Semantic Scholar
The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation
H. Hreggvidsdóttir, T. Östberg, H. Wähämaa, H. Schierbeck +6 more
2009Journal of Leukocyte Biology329 citations
Semantic Scholar
Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block
S. Salomonsson, S. Sonesson, L. Ottosson, S. Muhallab +6 more
2005Journal of Experimental Medicine184 citations Open access
Semantic Scholar
Monoclonal Anti-HMGB1 (High Mobility Group Box Chromosomal Protein 1) Antibody Protection in Two Experimental Arthritis Models
H. Schierbeck, P. Lundbäck, K. Palmblad, L. Klevenvall +3 more
2011Molecular Medicine129 citations Open access
Semantic Scholar
Interferon-α Induces Up-regulation and Nuclear Translocation of the Ro52 Autoantigen as Detected by a Panel of Novel Ro52-specific Monoclonal Antibodies
L. Strandberg, A. Ambrosi, A. Espinosa, L. Ottosson +6 more
2008Journal of Clinical Immunology111 citations
Semantic Scholar
A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug‐induced liver injury and postinjury inflammation in mice
P. Lundbäck, Jonathan D. Lea, A. Sowińska, L. Ottosson +14 more
2016Hepatology100 citations Open access
Semantic Scholar
Scan-o-matic: High-Resolution Microbial Phenomics at a Massive Scale
Martin Zackrisson, J. Hallin, L. Ottosson, Peter Dahl +10 more
2015G3: Genes, Genomes, Genetics80 citations Open access
Semantic Scholar
Robustness and fragility in the yeast high osmolarity glycerol (HOG) signal-transduction pathway
Marcus Krantz, Doryaneh Ahmadpour, L. Ottosson, J. Warringer +6 more
2009Molecular Systems Biology66 citations Open access
Semantic Scholar
Interferon-alpha induces up-regulation and nuclear translocation of the Ro52 autoantigen as detected by a panel of novel Ro52-specific monoclonal antibodies.
L. Strandberg, A. Ambrosi, A. Espinosa, L. Ottosson +6 more
2008Journal of Clinical Immunology66 citations
Semantic Scholar
Structural, functional and immunologic characterization of folded subdomains in the Ro52 protein targeted in Sjögren's syndrome.
L. Ottosson, J. Hennig, A. Espinosa, S. Brauner +2 more
2006Molecular Immunology62 citations
Semantic Scholar
Redox modifications of cysteine residues regulate the cytokine activity of HMGB1
Huan Yang, P. Lundbäck, L. Ottosson, H. Erlandsson-Harris +5 more
2021Molecular Medicine57 citations Open access
Semantic Scholar
Neuroinflammation in Response to Intracerebral Injections of Different HMGB1 Redox Isoforms
Hannah Aucott, J. Lundberg, Henna Salo, L. Klevenvall +5 more
2018Journal of Innate Immunity48 citations Open access
Semantic Scholar
Maternal MHC Regulates Generation of Pathogenic Antibodies and Fetal MHC-Encoded Genes Determine Susceptibility in Congenital Heart Block
L. Strandberg, A. Ambrosi, M. Jagodic, V. Dzikaite +14 more
2010Journal of Immunology35 citations Open access
Semantic Scholar
Antibodies against High Mobility Group Box protein-1 (HMGB1) versus other anti-nuclear antibody fine-specificities and disease activity in systemic lupus erythematosus
L. Wirestam, H. Schierbeck, T. Skogh, I. Gunnarsson +4 more
2015Arthritis Research & Therapy33 citations Open access
Semantic Scholar
Structural Organization and Zn2+-dependent Subdomain Interactions Involving Autoantigenic Epitopes in the Ring-B-box-Coiled-coil (RBCC) Region of Ro52*
J. Hennig, L. Ottosson, C. Andrésen, L. Horvath +4 more
2005Journal of Biological Chemistry31 citations Open access
Semantic Scholar
Structurally Derived Mutations Define Congenital Heart Block‐Related Epitopes Within the 200–239 Amino Acid Stretch of the Ro52 Protein
L. Ottosson, S. Salomonsson, J. Hennig, S. Sonesson +5 more
2005Scandinavian Journal of Immunology30 citations Open access
Semantic Scholar
Therapeutic blockade of HMGB1 reduces early motor deficits, but not survival in the SOD1G93A mouse model of amyotrophic lateral sclerosis
John D. Lee, Ning Liu, S. Levin, L. Ottosson +3 more
2019Journal of Neuroinflammation26 citations Open access
Semantic Scholar
Cloning and characterization of two human Ro52-specific monoclonal autoantibodies directed towards a domain associated with congenital heart block.
S. Salomonsson, L. Ottosson, Pär Säfsten, D. Hof +4 more
2004Journal of Autoimmunity26 citations
Semantic Scholar
Sulfate Assimilation Mediates Tellurite Reduction and Toxicity in Saccharomyces cerevisiae
L. Ottosson, Katarina Logg, Sebastian Ibstedt, P. Sunnerhagen +3 more
2010Eukaryotic Cell24 citations Open access
Semantic Scholar
The Ile128Thr polymorphism influences stability and ligand binding properties of the microsomal triglyceride transfer protein Published, JLR Papers in Press, April 14, 2006.
Helena Ledmyr, L. Ottosson, M. Sunnerhagen, E. Ehrenborg
2006Journal of Lipid Research22 citations Open access
Semantic Scholar
TLR4-dependant pro-inflammatory effects of HMGB1 on human adipocyte
M. Gunasekaran, Anne-Laurence Virama-Latchoumy, A. Girard, Cynthia Planesse +6 more
2016Adipocyte19 citations Open access
Semantic Scholar
Autoantibodies to the functionally active RING-domain of Ro52/SSA are associated with disease activity in patients with lupus
M. Kvarnström, V. Dzikaite-Ottosson, L. Ottosson, J. Gustafsson +3 more
2013Lupus18 citations
Semantic Scholar
Chlamydia trachomatis PCR (Cobas Amplicor) in women: endocervical specimen transported in a specimen of urine versus endocervical and urethral specimens in 2-SP medium versus urine specimen only
A. Airell, L. Ottosson, S. Bygdeman, H. Carlberg +3 more
2000International Journal of STD and AIDS16 citations
Semantic Scholar
Rat perichondrium transplanted to articular cartilage defects forms articular-like, hyaline cartilage
Zelong Dou, D. Muder, Marta Baroncelli, Ameya D. Bendre +4 more
2020bioRxiv10 citations Open access
Semantic Scholar
Anti-Citrullinated Protein Antibody Reactivity towards Neutrophil-Derived Antigens: Clonal Diversity and Inter-Individual Variation
A. Cîrciumaru, Marcelo Afonso, H. Wähämaa, A. Krishnamurthy +13 more
2023Biomolecules8 citations Open access
Semantic Scholar
Identification of discrete epitopes of Ro52p200 and association with fetal cardiac conduction system manifestations in a rodent model
Ariela Hoxha, A. Ruffatti, A. Ambrosi, Vijole Ottosson +6 more
2016Clinical and Experimental Immunology8 citations Open access
Semantic Scholar
Retraction Note to: Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1)
Huan Yang, P. Lundbäck, L. Ottosson, H. Erlandsson-Harris +6 more
2020Molecular Medicine5 citations Open access
Semantic Scholar
Expression of Concern to: Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1)
Huan Yang, P. Lundbäck, L. Ottosson, H. Erlandsson-Harris +6 more
2020Molecular Medicine5 citations Open access
Semantic Scholar
A pH-induced modification of CII increases its arthritogenic properties.
K. Lundberg, L. Ottosson, E. Westman, M. Sunnerhagen +2 more
2004Journal of Autoimmunity4 citations
Semantic Scholar
Anti HMGB1 treatment reduces inflammation in models of experimental autoimmunity
P. Lundbäck, Lena Klevenvall, L. Ottosson, Hanna Schierbeck +3 more
20123 citations Open access
Semantic Scholar
Erratum to: Redox Modification of Cysteine Residues Regulates the Cytokine Activity of High Mobility Group Box-1 (HMGB1)
Huan Yang, P. Lundbäck, L. Ottosson, H. Erlandsson-Harris +6 more
20122 citations Open access
Semantic Scholar
The pro-inflammatory effect of HMGB1, a mediator of inflammation in arthritis, is dependent on the redox status of the protein
L. Ottosson, P. Lundbäck, H. Hreggvidsdóttir, Huan Yang +4 more
20122 citations Open access
Semantic Scholar
OR.61. Anti-Ro52 Antibodies Inducing Heart Block Cross-react with Alpha-enolase
A. Ambrosi, L. Strandberg, V. Dzikaite, L. Ottosson +2 more
20082 citations
Semantic Scholar
Growth plate cartilage transplanted to the articular surface remodels into articular-like cartilage in a process promoted by the synovial joint microenvironment
Zelong Dou, Michael Chau, Marta Baroncelli, Ameya D. Bendre +3 more
20201 citations Open access
Semantic Scholar
Synovial cells secrete a temperature-stable protein that inhibits hypertrophic differentiation and induces articular cartilage differentiation of chondrocytes in vitro
Marta Baroncelli, Zelong Dou, E. Landman, Michael Chau +2 more
20201 citations Open access
Semantic Scholar
Autoantibodies to the functionally active RING-domain of Ro52/SSA associate with clinical activity in a subset of patients with lupus
M. Kvarnström, V. Dzikaite, L. Ottosson, I. Gunnarsson +2 more
20121 citations Open access
Semantic Scholar
Redox modifications of cysteine residues regulate the cytokine activity of HMGB1
Huan Yang, P. Lundbäck, L. Ottosson, H. Erlandsson-Harris +5 more
2021Molecular Medicine0 citations Open access
Semantic Scholar
Humanized anti-HMGB1 antibody therapy attenuates in vivo acetaminophen-induced liver injury
Jonathan D. Lea, P. Lundbäck, L. Ottosson, J. Sharkey +7 more
20140 citations
Semantic Scholar
THU0042 Autoantibodies against High Mobility Group Box Protein-1 in Systemic Lupus Erythematosus: Association with Disease Activity and Other Antinuclear Antibodies
C. Sjöwall, L. Wirestam, J. Wetterö, L. Ottosson +3 more
20140 citations
Semantic Scholar
OP0084 Cardiopathogenic Role of Human RO/SSA and LA/SSA Antibodies Demonstrated in a Novel Animal Model of Congenital Heart Block
Ariela Hoxha, A. Ruffatti, Vijole Ottosson, L. Ottosson +5 more
20130 citations
Semantic Scholar
AB0693 Autoantibodies to the functionally active ring-domain of RO52/SSA associate with clinical activity in a subset of patients with lupus
M. Kvarnström, Vijole Dzikaite, L. Ottosson, I. Gunnarsson +2 more
20120 citations
Semantic Scholar
Cellular Resilience and Fragility in Response to Environmental and Gene Expression Perturbations
L. Ottosson
20120 citations
Semantic Scholar
Successful therapy with anti-HMGB1 monoclonal antibodies in two separate experimental arthritis models
H. Schierbeck, P. Lundbäck, K. Palmblad, L. Klevenvall +6 more
20110 citations Open access
Semantic Scholar
Susceptibility in Congenital Heart Block MHC-Encoded Genes Determine Pathogenic Antibodies and Fetal Maternal MHC Regulates Generation of
T. Olsson, M. Wahren-Herlenius, der Graaf, V. Kuchroo +16 more
20100 citations
Semantic Scholar
Robustness and fragility in the high osmolarity glycerol (HOG) pathway in S. cerevisiae
Marcus Krantz, Doryaneh Ahmadpour, L. Ottosson, J. Warringer +6 more
2009International Conference on Systems0 citations
Semantic Scholar
Robustness and fragility in the yeast High Osmolarity signal transduction pathway
Marcus Krantz, L. Ottosson, Doryaneh Ahmadpour, J. Warringer +5 more
2008International Conference on Systems0 citations
Semantic Scholar
Sa.43. Identification of the Specific Sjögren-syndrome Related Maternal Ro52 Autoantibodies that Induce Heart Block in the Fetus During Pregnancy
V. Dzikaite, L. Strandberg, A. Ambrosi, L. Ottosson +4 more
20080 citations
Semantic Scholar
Robustness analysis of HOG pathway related genes in budding yeast
L. Ottosson, Doryaneh Ahmadpour, Marcus Krantz, J. Warringer +3 more
20070 citations
Semantic Scholar
Robustness analysis of HOG pathway related genes in Saccharomyces cerevisiae
Doryaneh Ahmadpour, L. Ottosson, Marcus Krantz, J. Warringer +2 more
20070 citations
Semantic Scholar
Robustness analysis of HOG pathway genes in Saccharomyces cerevisiae
Doryaneh Ahmadpour, L. Ottosson, Marcus Krantz, J. Warringer +2 more
20060 citations
Semantic Scholar

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