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V. Kuchroo · SciRah

Researcher profile · Semantic Scholar

V. Kuchroo

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V. Kuchroo — researcher profile on SciRah

h-index: 153
Works: 599
Citations: 108K

Most-cited papers

TIM3 comes of age as an inhibitory receptor
Y. Wolf, A. Anderson, V. Kuchroo
2019Nature reviews. Immunology836 citations Open access
Semantic Scholar
Spatially organized multicellular immune hubs in human colorectal cancer
K. Pelka, Matan Hofree, Jonathan H. Chen, Siranush Sarkizova +68 more
2021Cell811 citations Open access
Semantic Scholar
Checkpoint blockade immunotherapy induces dynamic changes in PD-1−CD8+ tumor-infiltrating T cells
S. Kurtuluş, A. Madi, Giulia Escobar, M. Klapholz +9 more
2019Immunity565 citations Open access
Semantic Scholar
Metabolic Modeling of Single Th17 Cells Reveals Regulators of Autoimmunity
Allon Wagner, Chao Wang, J. Fessler, D. DeTomaso +22 more
2021Cell467 citations Open access
Semantic Scholar
TIM-3 restrains anti-tumour immunity by regulating inflammasome activation
Karen O. Dixon, M. Tabaka, Markus A. Schramm, S. Xiao +6 more
2021Nature346 citations Open access
Semantic Scholar
Gut-innervating nociceptor neurons regulate Peyer’s Patch Microfold cells and SFB levels to mediate Salmonella host defense
N. Lai, Melissa A. Musser, Felipe A. Pinho-Ribeiro, Pankaj Baral +23 more
2019Cell306 citations Open access
Semantic Scholar
Polyamine metabolism is a central determinant of helper T cell lineage fidelity
Daniel J. Puleston, Francesc Baixauli, David E Sanin, Joy Edwards-Hicks +22 more
2021Cell282 citations Open access
Semantic Scholar
KIM-1 Mediates Fatty Acid Uptake by Renal Tubular Cells to Promote Progressive Diabetic Kidney Disease
Yutaro Mori, A. Ajay, Jae-Hyung Chang, S. Mou +15 more
2021Cell Metabolism271 citations Open access
Semantic Scholar
Transcriptional atlas of intestinal immune cells reveals that neuropeptide α-CGRP modulates group 2 innate lymphoid cell responses
He-Ping Xu, Jiarui Ding, Caroline B. M. Porter, Antonia Wallrapp +17 more
2019Immunity248 citations Open access
Semantic Scholar
Th17 cell heterogeneity and its role in tissue inflammation
Alexandra Schnell, D. Littman, V. Kuchroo
2023Nature Immunology244 citations
Semantic Scholar
Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity
Alexandra Schnell, Ling-Lin Huang, Meromit Singer, A. Singaraju +12 more
2021Cell241 citations Open access
Semantic Scholar
TIGIT predominantly regulates the immune response via regulatory T cells
S. Kurtuluş, K. Sakuishi, S. Ngiow, N. Joller +5 more
2024Journal of Clinical Investigation234 citations Open access
Semantic Scholar
Calcitonin gene related peptide negatively regulates alarmin-driven type 2 innate lymphoid cell responses
Antonia Wallrapp, Patrick R. Burkett, Samantha J. Riesenfeld, Se-Jin Kim +13 more
2019Immunity233 citations Open access
Semantic Scholar
Endogenous glucocorticoid signaling regulates effector differentiation and development of dysfunction in CD8+ T cells in the tumor microenvironment
Nandini Acharya, A. Madi, Hui-Yuan Zhang, M. Klapholz +16 more
2020Immunity209 citations Open access
Semantic Scholar
Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses
Rachel L. Clement, Joe Daccache, M. Mohammed, Alos B. Diallo +5 more
2019Nature Immunology209 citations Open access
Semantic Scholar
The yin and yang of co-inhibitory receptors: toward anti-tumor immunity without autoimmunity
Alexandra Schnell, L. Bod, A. Madi, V. Kuchroo
2020Cell Research189 citations Open access
Semantic Scholar
Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells
L. Sanmarco, Joseph M. Rone, C. Polonio, Gonzalo Fernandez Lahore +31 more
2023Nature187 citations Open access
Semantic Scholar
B-cell specific checkpoint molecules that regulate anti-tumor immunity
L. Bod, Yoon-Chul Kye, Jingwen Shi, E. Triglia +23 more
2023Nature155 citations Open access
Semantic Scholar
Functional anti-TIGIT antibodies regulate development of autoimmunity and anti-tumor immunity
Karen O. Dixon, M. Schorer, James T. Nevin, Yassaman Etminan +10 more
2018Journal of Immunology151 citations Open access
Semantic Scholar
A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes
Li-Jun Qi, Michael Iskols, David Shi, Pranav M. Reddy +8 more
2024Cell146 citations Open access
Semantic Scholar
Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function
Dan-Yang He, He-Ping Xu, Hui-Yuan Zhang, Ruihan Tang +16 more
2021Immunity146 citations Open access
Semantic Scholar
Tim-3: A co-receptor with diverse roles in T cell exhaustion and tolerance.
Ruihan Tang, M. Rangachari, V. Kuchroo
2019Seminars in Immunology141 citations
Semantic Scholar
Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells
T. Sumida, Shai Dulberg, J. Schupp, M. Lincoln +8 more
2020Nature Immunology135 citations Open access
Semantic Scholar
Droplet-based forward genetic screening of astrocyte–microglia cross-talk
Michael A. Wheeler, I. Clark, Hong-Gyun Lee, Zhao-Rong Li +27 more
2023Science106 citations Open access
Semantic Scholar
An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets
Hui-Yuan Zhang, A. Madi, N. Yosef, N. Chihara +21 more
2020Cell Reports81 citations Open access
Semantic Scholar
Combinatorial prediction of marker panels from single‐cell transcriptomic data
Conor Delaney, Alexandra Schnell, Louis V. Cammarata, Aaron Yao‐Smith +3 more
2019bioRxiv80 citations Open access
Semantic Scholar
Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut
J. Duan, J. D. Matute, L. Unger, T. Hanley +30 more
2023Immunity79 citations Open access
Semantic Scholar
Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis
Duygu Ozmadenci, J. S. Shankara Narayanan, J. Andrew, M. Ojalill +16 more
2022Proceedings of the National Academy of Sciences of the United States of America74 citations Open access
Semantic Scholar
Cytokines and transcription factors in the differentiation of CD4+ T helper cell subsets and induction of tissue inflammation and autoimmunity
Mathias Pawlak, Allen W. Ho, V. Kuchroo
2020Current Opinion in Immunology74 citations Open access
Semantic Scholar
Neuropeptide signaling orchestrates T cell differentiation
Yu Hou, Linyu Sun, M. LaFleur, Linglin Huang +21 more
2024Nature73 citations Open access
Semantic Scholar
Beyond T cell exhaustion: TIM-3 regulation of myeloid cells
Karen O. Dixon, Gonzalo Fernandez Lahore, V. Kuchroo
2024Science immunology71 citations
Semantic Scholar
Age-related dopaminergic innervation augments T helper 2-type allergic inflammation in the postnatal lung
Wei Wang, J. Cohen, Antonia Wallrapp, K. Trieu +8 more
2019Immunity68 citations Open access
Semantic Scholar
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
Pablo Hernández-Malmierca, Dominik Vonficht, Alexandra Schnell, H. Uckelmann +38 more
2022Cell Stem Cell66 citations Open access
Semantic Scholar
Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation
S. Xiao, L. Bod, N. Pochet, S. Kota +12 more
2020Cell Reports61 citations Open access
Semantic Scholar
Foxo1 controls gut homeostasis and commensalism by regulating mucus secretion
Zuo-Jia Chen, Jia-Lie Luo, Jian Li, Girak Kim +13 more
2021Journal of Experimental Medicine57 citations Open access
Semantic Scholar
Epigenetic and transcriptional mechanisms for the regulation of IL-10
Hui-Yuan Zhang, V. Kuchroo
2019Seminars in Immunology55 citations Open access
Semantic Scholar
Tim-3 mediates T cell trogocytosis to limit antitumor immunity
Ornella Pagliano, Robert M. Morrison, Joe-Marc Chauvin, Hridesh Banerjee +29 more
2022Journal of Clinical Investigation52 citations Open access
Semantic Scholar
Systems-based approaches to study immunometabolism
V. Purohit, Allon Wagner, N. Yosef, V. Kuchroo
2022Cellular & Molecular Immunology50 citations Open access
Semantic Scholar
Activation Pathways that Promote CD4+ T Cells to Break Tolerance in Autoimmune Diseases
S. Krovi, V. Kuchroo
2022Immunological Reviews49 citations Open access
Semantic Scholar
Chronic stress physically spares but functionally impairs innate-like invariant T cells
Patrick T. Rudak, Joshua Choi, Katie M Parkins, K. Summers +9 more
2020Cell Reports49 citations Open access
Semantic Scholar
Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function
Ruihan Tang, Nandini Acharya, Ayshwarya Subramanian, V. Purohit +12 more
2022Science immunology48 citations Open access
Semantic Scholar
Induction of a colitogenic phenotype in Th1-like cells depends on interleukin 23 receptor signaling
Mathias Pawlak, D. DeTomaso, Alexandra Schnell, Gerd Meyer zu Horste +16 more
2022Immunity42 citations Open access
Semantic Scholar
Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion
Chen Zhu, Karen O. Dixon, Kathleen Newcomer, Guangxiang Gu +14 more
2021Science Advances38 citations Open access
Semantic Scholar
BACH2 regulates diversification of regulatory and proinflammatory chromatin states in TH17 cells
Pratiksha I. Thakore, Alexandra Schnell, Linglin Huang, Maryann Zhao +17 more
2024Nature Immunology37 citations Open access
Semantic Scholar
Aberrant expression of USF2 in refractory rheumatoid arthritis and its regulation of proinflammatory cytokines in Th17 cells
Dan Hu, Emily C. Tjon, K. Andersson, Gabriela M Molica +7 more
2020Proceedings of the National Academy of Sciences of the United States of America31 citations Open access
Semantic Scholar
Immune Checkpoint Molecule TIGIT Regulates Kidney T Cell Functions and Contributes to AKI
Sanjeev Noel, Kyungho Lee, Sepideh Gharaie, J. T. Kurzhagen +5 more
2023Journal of the American Society of Nephrology30 citations Open access
Semantic Scholar
Metabolic regulation and function of T helper cells in neuroinflammation
M. Spiljar, V. Kuchroo
2022Seminars in Immunopathology29 citations Open access
Semantic Scholar
Targeting PGLYRP1 promotes antitumor immunity while inhibiting autoimmune neuroinflammation
Alexandra Schnell, Linglin Huang, Brianna M L Regan, Vasundhara Singh +11 more
2023Nature Immunology28 citations
Semantic Scholar
IL-17A and IL-17F in tissue homeostasis, inflammation and regeneration
I. Adamopoulos, V. Kuchroo
2023Nature Reviews Rheumatology27 citations
Semantic Scholar
Role of Co-stimulatory Molecules in T Helper Cell Differentiation.
M. Schorer, V. Kuchroo, N. Joller
2019Advances in Experimental Medicine and Biology24 citations
Semantic Scholar

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