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R. Kember · SciRah

Researcher profile · Semantic Scholar

R. Kember

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R. Kember — researcher profile on SciRah

h-index: 30
Works: 138
Citations: 5,423

Most-cited papers

The power of genetic diversity in genome-wide association studies of lipids
Sarah E. Graham, S. Clarke, Kuan-Han H. Wu, S. Kanoni +496 more
2021Nature826 citations Open access
Semantic Scholar
Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program
Anurag Verma, J. Huffman, Alex A. Rodriguez, Mitchell Conery +67 more
2024Science413 citations Open access
Semantic Scholar
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations
C. Tcheandjieu, Xiang Zhu, A. Hilliard, S. Clarke +79 more
2022Nature Medicine317 citations Open access
Semantic Scholar
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
R. Linnér, T. Mallard, P. Barr, S. Sanchez-Roige +25 more
2021Nature Neuroscience305 citations Open access
Semantic Scholar
A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation
Marijana Vujković, S. Ramdas, Kim M. Lorenz, Xiu-Qing Guo +86 more
2022Nature Genetics174 citations Open access
Semantic Scholar
Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals
Hang Zhou, R. Kember, J. Deak, Heng Xu +45 more
2023Nature Medicine146 citations Open access
Semantic Scholar
The Penn Medicine BioBank: Towards a Genomics-Enabled Learning Healthcare System to Accelerate Precision Medicine in a Diverse Population
A. Verma, S. Damrauer, Nawar Naseer, J. Weaver +16 more
2022Journal of Personalized Medicine139 citations Open access
Semantic Scholar
Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci
J. Deak, Hang Zhou, M. Galimberti, D. Levey +16 more
2022Molecular Psychiatry113 citations Open access
Semantic Scholar
Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects in brain regions associated with addiction
R. Kember, R. Vickers-Smith, Heng Xu, S. Toikumo +11 more
2022Nature Neuroscience92 citations Open access
Semantic Scholar
Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors
F. Thibord, D. Klarin, J. Brody, Ming-Huei Chen +83 more
2022Circulation66 citations Open access
Semantic Scholar
Exome-wide evaluation of rare coding variants using electronic health records identifies new gene-phenotype associations
J. Park, A. Lucas, Xinyuan Zhang, Kumardeep Chaudhary +37 more
2021Nature Medicine55 citations Open access
Semantic Scholar
Kidney disease genetic risk variants alter lysosomal beta-mannosidase (MANBA) expression and disease severity
Xiang-Chen Gu, Hong-Liu Yang, Xin Sheng, Yi-An Ko +24 more
2021Science Translational Medicine52 citations Open access
Semantic Scholar
Polygenic prediction of body mass index and obesity through the life course and across ancestries
R. Smit, K. Wade, Qin Hui, J. Arias +496 more
2025Nature Medicine51 citations Open access
Semantic Scholar
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes
S. Toikumo, M. Jennings, B. Pham, Hyunjoon Lee +30 more
2024Nature Human Behaviour47 citations Open access
Semantic Scholar
Phenome-wide Association Analysis of Substance Use Disorders in a Deeply Phenotyped Sample
R. Kember, E. Hartwell, Heng Xu, James Rotenberg +4 more
2022medRxiv47 citations Open access
Semantic Scholar
High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease
C. Tcheandjieu, K. Xiao, H. Tejeda, J. Lynch +99 more
2022Nature Genetics47 citations Open access
Semantic Scholar
Genetic Underpinnings of the Transition From Alcohol Consumption to Alcohol Use Disorder: Shared and Unique Genetic Architectures in a Cross-Ancestry Sample
R. Kember, R. Vickers-Smith, Hang Zhou, Heng Xu +8 more
2021medRxiv44 citations Open access
Semantic Scholar
A multi-ancestry genetic study of pain intensity in 598,339 veterans
S. Toikumo, R. Vickers-Smith, Zeal Jinwala, Heng Xu +15 more
2024Nature Medicine42 citations Open access
Semantic Scholar
Association of Inherited Mutations in DNA Repair Genes with Localized Prostate Cancer
Daniel J. Lee, R. Hausler, Anh Le, G. Kelly +17 more
2021European Urology35 citations Open access
Semantic Scholar
Racial and Ethnic Bias in the Diagnosis of Alcohol Use Disorder in Veterans
R. Vickers-Smith, Amy C. Justice, W. Becker, C. Rentsch +7 more
2023American Journal of Psychiatry30 citations Open access
Semantic Scholar
Diversity and Scale: Genetic Architecture of 2,068 Traits in the VA Million Veteran Program
A. Verma, J. Huffman, Alex A. Rodriguez, Mitchell Conery +64 more
2023medRxiv27 citations Open access
Semantic Scholar
Performance of polygenic risk scores for cancer prediction in a racially diverse academic biobank
Louise Wang, Heena Desai, S. Verma, Anh Le +11 more
2021medRxiv25 citations Open access
Semantic Scholar
Substance use and common contributors to morbidity: A genetics perspective
S. Sanchez-Roige, R. Kember, A. Agrawal
2022EBioMedicine22 citations Open access
Semantic Scholar
Multi-ancestry study of the genetics of problematic alcohol use in >1 million individuals
Hang Zhou, R. Kember, Joseph D. Deak, Heng Xu +43 more
2023medRxiv20 citations Open access
Semantic Scholar
Genetic contribution to the comorbidity between attention-deficit/hyperactivity disorder and substance use disorders
D. Koller, M. Mitjans, Manuela R. Kouakou, E. Friligkou +20 more
2024Psychiatry Research19 citations Open access
Semantic Scholar
Germline Exome Sequencing for Men with Testicular Germ Cell Tumor Reveals Coding Defects in Chromosomal Segregation and Protein-targeting Genes
Louise C. Pyle, Jung Kim, J. Bradfield, S. Damrauer +17 more
2023European Urology19 citations Open access
Semantic Scholar
Identifying genetic loci and phenomic associations of substance use traits: A multi-trait analysis of GWAS (MTAG) study
Heng Xu, S. Toikumo, R. Crist, K. Głogowska +7 more
2023Addiction18 citations
Semantic Scholar
Integrating human brain proteomic data with genome-wide association study findings identifies novel brain proteins in substance use traits
S. Toikumo, Heng Xu, J. Gelernter, R. Kember +1 more
2022Neuropsychopharmacology17 citations Open access
Semantic Scholar
Genetic liability for substance use associated with medical comorbidities in electronic health records of African- and European-ancestry individuals
E. Hartwell, A. Merikangas, S. Verma, M. Ritchie +2 more
2021medRxiv17 citations Open access
Semantic Scholar
The impact of removing former drinkers from genome-wide association studies of AUDIT-C
Cecilia Dao, Hang Zhou, Aeron M. Small, Kirsha S. Gordon +8 more
2021Addiction16 citations Open access
Semantic Scholar
Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes
J. Bradfield, R. Kember, A. Ulrich, Z. Balkhiyarova +102 more
2024Genome Biology15 citations Open access
Semantic Scholar
Pleiotropy and genetically inferred causality linking multisite chronic pain to substance use disorders
D. Koller, E. Friligkou, B. Stiltner, G. Pathak +12 more
2024Molecular Psychiatry14 citations Open access
Semantic Scholar
Identifying High-Risk Comorbidities Associated with Opioid Use Patterns Using Electronic Health Record Prescription Data
M. Jennings, Hyunjoon Lee, D. Rocha, S. Bianchi +15 more
2022Complex Psychiatry14 citations Open access
Semantic Scholar
Author Correction: The power of genetic diversity in genome-wide association studies of lipids
Sarah E. Graham, S. Clarke, Kuan-Han H. Wu, S. Kanoni +496 more
2023Nature12 citations Open access
Semantic Scholar
Does Polygenic Risk for Substance-Related Traits Predict Ages of Onset and Progression of Symptoms?
H. Kranzler, R. Feinn, Heng Xu, Brendan L. Ho +7 more
2023Addiction12 citations Open access
Semantic Scholar
Considerations for the application of polygenic scores to clinical care of individuals with substance use disorders
R. Kember, C. Davis, K. Feuer, H. Kranzler
2024Journal of Clinical Investigation11 citations Open access
Semantic Scholar
Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects on brain
R. Kember, R. Vickers-Smith, Heng Xu, S. Toikumo +11 more
2021medRxiv11 citations Open access
Semantic Scholar
A genome-wide association study for nonalcoholic fatty liver disease identifies novel genetic loci and trait-relevant candidate genes in the Million Veteran Program.
M. Vujkovic, S. Ramdas, Kim M. Lorenz, Xiu-Qing Guo +86 more
2021medRxiv11 citations Open access
Semantic Scholar
A large-scale multi-ethnic genome-wide association study of coronary artery disease
T. Assimes, C. Tcheandjieu, Xiang Zhu, A. Hilliard +78 more
202111 citations Open access
Semantic Scholar
Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and somatic traits
Emily E. Hartwell, Zeal Jinwala, John Milone, Sarah Ramirez +3 more
2024Neuropsychopharmacology10 citations Open access
Semantic Scholar
Gene × environment effects and mediation involving adverse childhood events, mood and anxiety disorders, and substance dependence
H. Kranzler, C. Davis, Richard Feinn, Zeal Jinwala +12 more
2024Nature Human Behaviour10 citations
Semantic Scholar
The Relationship between Alcohol- and Sleep-related Traits: Results from Polygenic Risk Score Analyses and Mendelian Randomization Studies
S. Chakravorty, R. Kember, D. Mazzotti, H. Dashti +3 more
2023medRxiv10 citations Open access
Semantic Scholar
A Mendelian randomization study of alcohol use and cardiometabolic disease risk in a multi-ancestry population from the VA Million Veteran Program
R. Kember, C. Rentsch, J. Lynch, M. Vujkovic +4 more
2024Alcohol, clinical & experimental research9 citations Open access
Semantic Scholar
A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens
B. Reiner, S. Chehimi, R. Merkel, S. Toikumo +6 more
2024bioRxiv9 citations Open access
Semantic Scholar
Genome-wide significant risk loci for mood disorders in the Old Order Amish founder population
Elizabeth M. Humphries, K. Ahn, R. Kember, F. Lopes +15 more
2022Molecular Psychiatry9 citations Open access
Semantic Scholar
Major Depressive Disorder Impacts Peripheral Artery Disease Risk Through Intermediary Risk Factors
G. Shakt, Noah L. Tsao, M. Levin, V. Walker +6 more
2024Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease8 citations Open access
Semantic Scholar
Polygenic risk scores for cardiometabolic traits demonstrate importance of ancestry for predictive precision medicine
R. Kember, S. Verma, A. Verma, B. Xiao +7 more
2024Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing8 citations Open access
Semantic Scholar
The genetic architecture of pain intensity in a sample of 598,339 U.S. veterans
S. Toikumo, R. Vickers-Smith, Zeal Jinwala, Heng Xu +15 more
2023medRxiv8 citations Open access
Semantic Scholar
Multi-trait genome-wide association analyses leveraging alcohol use disorder findings identify novel loci for smoking behaviors in the Million Veteran Program
You-Shu Cheng, Cecilia Dao, Hang Zhou, Bo-Yang Li +7 more
2022bioRxiv8 citations Open access
Semantic Scholar
Genome-wide association study and multi-trait analysis of opioid use disorder identifies novel associations in 639,709 individuals of European and African ancestry.
J. Deak, Hang Zhou, M. Galimberti, D. Levey +16 more
2021medRxiv8 citations Open access
Semantic Scholar

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