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C. Kenific · SciRah

Researcher profile · Semantic Scholar

C. Kenific

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C. Kenific — researcher profile on SciRah

h-index: 24
Works: 45
Citations: 11K

Most-cited papers

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
D. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, M. Abdellatif +496 more
2021Autophagy4,016 citations Open access
Semantic Scholar
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric-flow field-flow fractionation
Haiying Zhang, Daniela Freitas, Han Sang Kim, K. Fabijanic +38 more
2018Nature Cell Biology1,469 citations Open access
Semantic Scholar
Exosome-Mediated Metastasis: Communication from a Distance.
I. Wortzel, S. Dror, C. Kenific, D. Lyden
2019Developmental Cell1,129 citations Open access
Semantic Scholar
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
A. Hoshino, Han Sang Kim, L. Bojmar, K. Gyan +113 more
2020Cell1,118 citations Open access
Semantic Scholar
Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
R. Lock, Srirupa Roy, C. Kenific, Judy S. Su +3 more
2011Molecular Biology of the Cell475 citations Open access
Semantic Scholar
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis
Gonçalo M. C. Rodrigues, A. Hoshino, C. Kenific, Irina R. Matei +43 more
2019Nature Cell Biology369 citations Open access
Semantic Scholar
Autophagy and Metastasis: Another double-edged sword
C. Kenific, A. Thorburn, Jayanta Debnath
2009Current Opinion in Cell Biology311 citations Open access
Semantic Scholar
Autophagy dependent production of secreted factors facilitates oncogenic RAS-driven invasion
R. Lock, C. Kenific, Andrew M. Leidal, Eduardo Salas +1 more
2014Cancer Discovery260 citations Open access
Semantic Scholar
Cellular and metabolic functions for autophagy in cancer cells
C. Kenific, Jayanta Debnath
2014Trends in Cell Biology259 citations Open access
Semantic Scholar
Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2).
J. Methot, P. Chakravarty, M. Chénard, Joshua Close +22 more
2008Bioorganic & Medicinal Chemistry Letters188 citations Open access
Semantic Scholar
Inhibition of γ-Secretase Activity Inhibits Tumor Progression in a Mouse Model of Pancreatic Ductal Adenocarcinoma
R. Plentz, Ji-Sun Park, A. Rhim, D. Abravanel +9 more
2009Gastroenterology156 citations Open access
Semantic Scholar
NBR1 enables autophagy-dependent focal adhesion turnover
C. Kenific, Samantha J. Stehbens, J. Goldsmith, Andrew M. Leidal +4 more
2016Journal of Cell Biology155 citations Open access
Semantic Scholar
Extracellular vesicles and particles impact the systemic landscape of cancer
S. Lucotti, C. Kenific, Haiying Zhang, D. Lyden
2022EMBO Journal118 citations Open access
Semantic Scholar
Autophagy in adhesion and migration
C. Kenific, Torsten Wittmann, Jayanta Debnath
2016Journal of Cell Science108 citations Open access
Semantic Scholar
Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth During Mammary Tumor Progression
Timothy Marsh, C. Kenific, Deepthisri Suresh, Hugo Gonzalez +8 more
2020Developmental Cell107 citations Open access
Semantic Scholar
An exosome pathway without an ESCRT
C. Kenific, Haiying Zhang, D. Lyden
2020Cell Research84 citations Open access
Semantic Scholar
Down‐regulation of the Notch pathway mediated by a γ‐secretase inhibitor induces anti‐tumour effects in mouse models of T‐cell leukaemia
J. Tammam, C. Ware, C. Efferson, Jennifer O'Neil +23 more
2009British Journal of Pharmacology77 citations Open access
Semantic Scholar
Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2
S. Lucotti, Yusuke Ogitani, C. Kenific, Jacob Geri +41 more
2025Cell65 citations Open access
Semantic Scholar
Tumor-derived nanoseeds condition the soil for metastatic organotropism
Meng-Ying Hu, C. Kenific, N. Boudreau, D. Lyden
2023Seminars in Cancer Biology49 citations Open access
Semantic Scholar
Targeted degradation of the AML1/MDS1/EVI1 oncoprotein by arsenic trioxide.
D. Shackelford, C. Kenific, Agnieszka Blusztajn, S. Waxman +1 more
2006Cancer Research48 citations Open access
Semantic Scholar
Extracellular vesicle and particle isolation from human and murine cell lines, tissues, and bodily fluids
L. Bojmar, Han Sang Kim, G. Tobias, Fanny A. Pelissier Vatter +18 more
2020STAR Protocols39 citations Open access
Semantic Scholar
Purine derivatives as potent gamma-secretase modulators.
A. Rivkin, Sean P. Ahearn, Stephanie M. Chichetti, Christopher L. Hamblett +28 more
2010Bioorganic & Medicinal Chemistry Letters36 citations Open access
Semantic Scholar
Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1:2) optimization.
S. Kattar, Laura Surdi, Anna A. Zabierek, J. Methot +17 more
2009Bioorganic & Medicinal Chemistry Letters29 citations Open access
Semantic Scholar
Fluorinated piperidine acetic acids as gamma-secretase modulators.
Matthew G. Stanton, Jed Hubbs, D. Sloman, Christopher L. Hamblett +20 more
2010Bioorganic & Medicinal Chemistry Letters27 citations Open access
Semantic Scholar
Delayed and Prolonged Histone Hyperacetylation with a Selective HDAC1/HDAC2 Inhibitor.
J. Methot, D. M. Hoffman, D. Witter, Matthew G. Stanton +20 more
2014ACS Medicinal Chemistry Letters24 citations Open access
Semantic Scholar
NBR1-dependent selective autophagy is required for efficient cell-matrix adhesion site disassembly
C. Kenific, Jayanta Debnath
2016Autophagy22 citations Open access
Semantic Scholar
Non-reversible tissue fixation retains extracellular vesicles for in situ imaging
Mrinali Gupta, Sangeetha Tandalam, Shariss Ostrager, Alexander S. Lever +15 more
2019Nature Methods19 citations Open access
Semantic Scholar
Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeys.
C. Fischer, S. L. Zultanski, Hua Zhou, J. Methot +23 more
2015Bioorganic & Medicinal Chemistry Letters16 citations Open access
Semantic Scholar
Triazoles as γ-secretase modulators.
C. Fischer, S. L. Zultanski, Hua Zhou, J. Methot +20 more
2011Bioorganic & Medicinal Chemistry Letters16 citations Open access
Semantic Scholar
Pre-Metastatic Niche Formation Has Taken Its TOLL.
C. Kenific, Laura Nogués, D. Lyden
2016Cancer Cell14 citations Open access
Semantic Scholar
Potent benzoazepinone γ-secretase modulators with improved bioavailability.
J. Methot, C. Fischer, Chao-Ming Li, A. Rivkin +24 more
2015Bioorganic & Medicinal Chemistry Letters13 citations Open access
Semantic Scholar
Activated T cell extracellular vesicle DNA transfer enhances antigen presentation and anti-tumor immunity
Mengying Hu, Di-Ao Liu, I. Wortzel, Paul Collier +41 more
2026Cancer Cell5 citations Open access
Semantic Scholar
Tumor Extracellular Vesicles Impede Interferon Alert Responses.
C. Kenific, Gang Wang, D. Lyden
2019Cancer Cell4 citations Open access
Semantic Scholar
Characterization of human pre-implantation embryonic exosomes
V. Gunnala, Irina R. Matei, M. Toschi, A. Hoshino +7 more
2018Fertility and Sterility4 citations Open access
Semantic Scholar
BASIC—LIVER, PANCREAS, AND BILIARY TRACT Inhibition of -Secretase Activity Inhibits Tumor Progression in a Mouse Model of Pancreatic Ductal Adenocarcinoma
R. Plentz, A. Rhim, D. Abravanel, A. Hezel +8 more
20092 citations
Semantic Scholar
RESEARCH PAPER Down-regulation of the Notch pathway mediated by a g-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia
J. Tammam, C. Efferson, Sudhir Rao, J. Gorenstein +12 more
20091 citations
Semantic Scholar
High-quality Scanning Electron Microscopy Incorporated with a Freeze-drying and Gaseous Nitrogen-based Approach for Cell-extracellular Vesicle Interactions
Kunihiro Uryu, Nadine Soplop, Nancy Boudreau, C. Kenific +4 more
2024Microscopy and Microanalysis0 citations
Semantic Scholar
Advancement in Cellular Topographic and Nanoparticle Capture Imaging by High Resolution Microscopy Incorporating a Freeze-Drying and Gaseous Nitrogen-based Approach
Kunihiro Uryu, Nadine Soplop, T. Sheahan, M. Catanese +9 more
2023bioRxiv0 citations Open access
Semantic Scholar
Abstract C028: The lung pro-thrombotic niche drives cancer-associated thromboembolism and metastasis via extracellular vesicle ITGB2
S. Lucotti, Y. Ogitani, C. Kenific, L. Bojmar +16 more
2022Cancer Research0 citations
Semantic Scholar
Abstract 3138: The lung pro-thrombotic niche drives cancer-associated thromboembolism via exosomal ITGB2
S. Lucotti, Y. Ogitani, C. Kenific, L. Bojmar +16 more
2022Cancer Research0 citations
Semantic Scholar
Abstract 4805: The role of exosomes in fibrosarcoma progression
M. Nakajima, Stephen C. Searles, A. Hoshino, K. Offer +3 more
20170 citations
Semantic Scholar
Regulation of metastatic phenotypes by autophagy
C. Kenific
20150 citations
Semantic Scholar
Abstract 5433: Prolonged histone hyperacetylation with a novel class of HDAC1/2 selective inhibitors
J. Methot, M. Chénard, C. Joshua, C. Jonathan +20 more
20100 citations
Semantic Scholar
Mandarin Translations
J. Tammam, C. Ware, C. Efferson, J. O'Neil +23 more
20090 citations Open access
Semantic Scholar
Arsenic Trioxide Targets the MDS1 and EVI1- Containing Oncoproteins for Degradation by Proteasome Dependent and Independent Mechanisms.
D. Shackelford, C. Kenific, S. Waxman, R. Ren
20050 citations
Semantic Scholar

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