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F. Filipp · SciRah

Researcher profile · Semantic Scholar

F. Filipp

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F. Filipp — researcher profile on SciRah

h-index: 28
Works: 74
Citations: 2,755

Most-cited papers

Comparative Metabolic Flux Profiling of Melanoma Cell Lines
D. Scott, A. Richardson, F. Filipp, Christine A. Knutzen +4 more
2011Journal of Biological Chemistry339 citations Open access
Semantic Scholar
Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells
F. Filipp, David A. Scott, Ze'ev A. Ronai, A. Osterman +1 more
2012Pigment Cell & Melanoma Research186 citations Open access
Semantic Scholar
Recognition of a functional peroxisome type 1 target by the dynamic import receptor pex5p.
W. Stanley, F. Filipp, P. Kursula, Nicole Schüller +4 more
2006Molecules and Cells174 citations Open access
Semantic Scholar
Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities
N. Lanning, Joshua P. Castle, Simar J. Singh, A. N. León +5 more
2017Cancer & Metabolism160 citations Open access
Semantic Scholar
Determinants of conformational dimerization of Mad2 and its inhibition by p31comet
M. Mapelli, F. Filipp, Giulia Rancati, L. Massimiliano +7 more
2006EMBO Journal149 citations Open access
Semantic Scholar
Refinement of the androgen response element based on ChIP-Seq in androgen-insensitive and androgen-responsive prostate cancer cell lines
Stephen Wilson, Jianfei Qi, F. Filipp
2016Scientific Reports111 citations Open access
Semantic Scholar
Glutamine-fueled mitochondrial metabolism is decoupled from glycolysis in melanoma
F. Filipp, B. Ratnikov, J. De Ingeniis, J. Smith +2 more
2012Pigment Cell & Melanoma Research105 citations Open access
Semantic Scholar
Evaluation of integrin αvβ6 cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis
R. Kimura, Ling Wang, Bin Shen, L. Huo +38 more
2019Nature Communications100 citations Open access
Semantic Scholar
Cancer systems biology of TCGA SKCM: Efficient detection of genomic drivers in melanoma
Jian Guan, Rohit Gupta, F. Filipp
2015Scientific Reports95 citations Open access
Semantic Scholar
Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19
Christian Neufeld, F. Filipp, B. Simon, A. Neuhaus +8 more
2009EMBO Journal92 citations Open access
Semantic Scholar
Topography for independent binding of alpha-helical and PPII-helical ligands to a peroxisomal SH3 domain.
A. Douangamath, F. Filipp, A. Klein, P. Barnett +7 more
2002Molecules and Cells91 citations Open access
Semantic Scholar
Cistromic Reprogramming of the Diurnal Glucocorticoid Hormone Response by High-Fat Diet
F. Quagliarini, A. A. Mir, Kinga Balazs, M. Wierer +8 more
2019Molecules and Cells86 citations Open access
Semantic Scholar
The histone demethylase KDM3A regulates the transcriptional program of the androgen receptor in prostate cancer cells
Stephen Wilson, Ling-Ling Fan, N. Sahgal, Jianfei Qi +1 more
2017OncoTarget78 citations Open access
Semantic Scholar
Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes
Jessamy Tiffen, Dilini Gunatilake, S. Gallagher, K. Gowrishankar +12 more
2015OncoTarget78 citations Open access
Semantic Scholar
Opportunities for Artificial Intelligence in Advancing Precision Medicine
F. Filipp
2019Current Genetic Medicine Reports65 citations Open access
Semantic Scholar
EZH2 cooperates with DNA methylation to downregulate key tumour suppressors and interferon gene signatures in melanoma.
Jessamy Tiffen, S. Gallagher, F. Filipp, Dilini Gunatilake +9 more
2020Journal of Investigative Dermatology60 citations Open access
Semantic Scholar
Cancer metabolism meets systems biology: Pyruvate kinase isoform PKM2 is a metabolic master regulator
F. Filipp
2013Journal of Carcinogenesis57 citations Open access
Semantic Scholar
Precision medicine driven by cancer systems biology
F. Filipp
2017Cancer Metastasis Review50 citations Open access
Semantic Scholar
Somatic Copy Number Amplification and Hyperactivating Somatic Mutations of EZH2 Correlate With DNA Methylation and Drive Epigenetic Silencing of Genes Involved in Tumor Suppression and Immune Responses in Melanoma
Jessamy Tiffen, Stephen Wilson, S. Gallagher, P. Hersey +1 more
2016Neoplasia46 citations Open access
Semantic Scholar
Pharmacogenomic and clinical data link non-pharmacokinetic metabolic dysregulation to drug side effect pathogenesis
D. Zielinski, F. Filipp, A. Bordbar, Kasper Jensen +4 more
2015Nature Communications46 citations Open access
Semantic Scholar
Concurrent targeting of glutaminolysis and metabotropic glutamate receptor 1 (GRM1) reduces glutamate bioavailability in GRM1+ melanoma
Raj Shah, Simar J. Singh, K. Eddy, F. Filipp +1 more
2019Cancer Research44 citations Open access
Semantic Scholar
Down-regulation of FZD3 receptor suppresses growth and metastasis of human melanoma independently of canonical WNT signaling
Chen Li, Vincent T Nguyen, K. Clark, Tara Zahed +3 more
2019Proceedings of the National Academy of Sciences of the United States of America44 citations Open access
Semantic Scholar
A hexokinase isoenzyme switch in human liver cancer cells promotes lipogenesis and enhances innate immunity
Laure Perrin-Cocon, Pierre-Olivier Vidalain, Clémence Jacquemin, A. Aublin-Gex +11 more
2021Communications Biology39 citations Open access
Semantic Scholar
Chemoprevention Agents for Melanoma: A Path Forward into Phase III Clinical Trials
J. Jeter, T. Bowles, Clara Curiel-Lewandrowski, S. Swetter +39 more
2018Cancer39 citations Open access
Semantic Scholar
A network of epigenomic and transcriptional cooperation encompassing an epigenomic master regulator in cancer
Stephen Wilson, F. Filipp
2018npj Systems Biology and Applications37 citations Open access
Semantic Scholar
EZH2 as a mediator of treatment resistance in melanoma
Jessamy Tiffen, S. Gallagher, Hsin-Yi Tseng, F. Filipp +2 more
2016Pigment Cell & Melanoma Research34 citations Open access
Semantic Scholar
Systems biology analysis of mitogen activated protein kinase inhibitor resistance in malignant melanoma
Helma Zecena, D. Tveit, Zi Wang, Ahmed Farhat +9 more
2017bioRxiv32 citations Open access
Semantic Scholar
Hypermutation of DPYD Deregulates Pyrimidine Metabolism and Promotes Malignant Progression
Lauren Edwards, Rohit Gupta, F. Filipp
2015Molecular Cancer Research30 citations Open access
Semantic Scholar
Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation
A. Trivedi, A. Mehrotra, C. Baum, Brandon Lewis +6 more
2020Epigenetics & Chromatin27 citations Open access
Semantic Scholar
Crosstalk between epigenetics and metabolism—Yin and Yang of histone demethylases and methyltransferases in cancer
F. Filipp
2017Briefings in Functional Genomics27 citations Open access
Semantic Scholar
CD271 is a molecular switch with divergent roles in melanoma and melanocyte development
F. Filipp, Chen Li, Alexander D Boiko
2019Scientific Reports26 citations Open access
Semantic Scholar
Binding and pKa Modulation of a Polycyclic Substrate Analog in a Type II Polyketide Acyl Carrier Protein
R. Haushalter, F. Filipp, Kwang-Seuk Ko, R. Yu +2 more
2011ACS Chemical Biology25 citations Open access
Semantic Scholar
Probing lipid- and drug-binding domains with fluorescent dyes.
S. L. Black, W. Stanley, F. Filipp, Michelle Bhairo +5 more
2008Bioorganic & Medicinal Chemistry25 citations Open access
Semantic Scholar
Conformational plasticity of the lipid transfer protein SCP2.
F. Filipp, M. Sattler
2007Biochemistry25 citations Open access
Semantic Scholar
Metabolic shift in density-dependent stem cell differentiation
Simar J. Singh, W. Turner, D. Glaser, K. McCloskey +1 more
2017Cell Communication and Signaling19 citations Open access
Semantic Scholar
Labeling strategies for 13C-detected aligned-sample solid-state NMR of proteins
F. Filipp, Neeraj Sinha, Lena Jairam, Joel C. Bradley +1 more
2009Journal of magnetic resonance (San Diego, Calif. 1997 : Print)16 citations Open access
Semantic Scholar
Unusual binding of ursodeoxycholic acid to ileal bile acid binding protein: role in activation of FXRα[S]
Changming Fang, F. Filipp, J. Smith
2012Journal of Lipid Research15 citations Open access
Semantic Scholar
Tailoring 13C labeling for triple‐resonance solid‐state NMR experiments on aligned samples of proteins
Neeraj Sinha, F. Filipp, Lena Jairam, S. H. Park +2 more
2007Magnetic resonance in chemistry : MRC14 citations Open access
Semantic Scholar
Topography for Independent Binding of-Helical and PPII-Helical Ligands to a Peroxisomal SH 3
A. Douangamath, F. Filipp, A. Klein, P. Barnett +7 more
200213 citations
Semantic Scholar
Frontiers in Pigment Cell and Melanoma Research
F. Filipp, S. Birlea, M. Bosenberg, D. Brash +23 more
2018Pigment Cell & Melanoma Research12 citations Open access
Semantic Scholar
Insulin induces a shift in lipid and primary carbon metabolites in a model of fasting-induced insulin resistance
Keedrian I. Olmstead, M. L. La Frano, Johannes F. Fahrmann, D. Grapov +6 more
2017Metabolomics7 citations Open access
Semantic Scholar
A Gateway between Omics Data and Systems Biology
F. Filipp
2013Journal of Metabolomics & Systems Biology6 citations Open access
Semantic Scholar
Quiescence and aging of melanocyte stem cells and a novel association with programmed death-ligand 1
Joseph W. Palmer, Kyrene M. Villavicencio, Misgana I Idris, Ian J. Baranyk +6 more
2024iScience5 citations Open access
Semantic Scholar
Epigenetic and pharmacological control of pigmentation via Bromodomain Protein 9 (BRD9)
T. Basuroy, Megan R. Dreier, C. Baum, Thomas M Blomquist +3 more
2022Pigment Cell & Melanoma Research5 citations Open access
Semantic Scholar
Exploring Mechanisms of Glucose Uptake Regulation and Dilution Resistance in Growing Cancer Cells
D. Tveit, Gunhild Fjeld, Tormod Drengstig, F. Filipp +2 more
2020bioRxiv5 citations Open access
Semantic Scholar
The relationship between PD-L1 and quiescence in melanocyte stem cell aging
Joseph W. Palmer, Kyrene M. Villavicencio, Misgana I Idris, Dominique Weddle +3 more
2022bioRxiv3 citations Open access
Semantic Scholar
Lipogenesis and innate immunity in hepatocellular carcinoma cells reprogrammed by an isoenzyme switch of hexokinases
Laure Perrin-Cocon, Pierre-Olivier Vidalain, Clémence Jacquemin, A. Aublin-Gex +11 more
20202 citations Open access
Semantic Scholar
The triennial International Pigment Cell Conference (IPCC)
N. Box, L. Larue, P. Manga, L. Montoliu +2 more
2018Journal of Translational Medicine2 citations Open access
Semantic Scholar
An epigenetic master regulator teams up to become an epioncogene
Jianfei Qi, F. Filipp
2017OncoTarget2 citations Open access
Semantic Scholar
Spatial cancer systems biology resolves heterotypic interactions and identifies disruption of spatial hierarchy as a pathological driver event
F. Filipp
2023bioRxiv1 citations Open access
Semantic Scholar

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