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N. Morral · SciRah

Researcher profile · Semantic Scholar

N. Morral

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N. Morral — researcher profile on SciRah

h-index: 29
Works: 55
Citations: 3,581

Most-cited papers

Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity
G. Schiedner, N. Morral, R. J. Parks, Ying Wu +5 more
1998Nature Genetics690 citations
Semantic Scholar
Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons.
N. Morral, W. O'Neal, K. Rice, M. Leland +11 more
1999Proceedings of the National Academy of Sciences of the United States of America424 citations Open access
Semantic Scholar
High Doses of a Helper-Dependent Adenoviral Vector Yield Supraphysiological Levels of α 1-Antitrypsin with Negligible Toxicity
N. Morral, R. J. Parks, H. Zhou, C. Langston +5 more
1998270 citations
Semantic Scholar
Immune Responses to Reporter Proteins and High Viral Dose Limit Duration of Expression with Adenoviral Vectors: Comparison of E2a Wild Type and E2a Deleted Vectors
N. Morral, W. O'Neal, H. Zhou, C. Langston +1 more
1997Human Gene Therapy186 citations
Semantic Scholar
Lethal Toxicity, Severe Endothelial Injury, and a Threshold Effect with High Doses of an Adenoviral Vector in Baboons
N. Morral, W. O'Neal, K. Rice, M. Leland +5 more
2002Human Gene Therapy169 citations
Semantic Scholar
The origin of the major cystic fibrosis mutation (delta F508) in European populations.
N. Morral, J. Bertranpetit, X. Estivill, V. Nunes +6 more
1994Nature Genetics158 citations
Semantic Scholar
Sterol Regulatory Element-binding Protein-1 (SREBP-1) Is Required to Regulate Glycogen Synthesis and Gluconeogenic Gene Expression in Mouse Liver*
R. Ruíz, V. Jideonwo, M. Ahn, Sneha Surendran +10 more
2014Journal of Biological Chemistry142 citations Open access
Semantic Scholar
CA/GT microsatellite alleles within the cystic fibrosis transmembrane conductance regulator (CFTR) gene are not generated by unequal crossingover.
N. Morral, V. Nunes, T. Casals, X. Estivill
1991Genomics109 citations
Semantic Scholar
Microsatellite haplotypes for cystic fibrosis: mutation frameworks and evolutionary tracers.
N. Morral, V. Nunes, T. Casals, M. Chillón +3 more
1993Human Molecular Genetics95 citations
Semantic Scholar
Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice
José M. Irimia, Catalina M. Meyer, Dyann M. Segvich, Sneha Surendran +3 more
2017Journal of Biological Chemistry94 citations Open access
Semantic Scholar
Toxicity Associated with Repeated Administration of First-Generation Adenovirus Vectors Does Not Occur with a Helper-Dependent Vector
W. O'Neal, H. Zhou, N. Morral, C. Langston +4 more
2000Molecular Medicine92 citations Open access
Semantic Scholar
Gene therapy for inherited retinal and optic nerve degenerations
Nicholas A Moore, N. Morral, T. Ciulla, P. Bracha
2018Expert Opinion on Biological Therapy83 citations Open access
Semantic Scholar
Novel targets and therapeutic strategies for type 2 diabetes.
N. Morral
2003Trends in endocrinology and metabolism66 citations
Semantic Scholar
Haplotype analysis of 94 cystic fibrosis mutations with seven polymorphic CFTR DNA markers
N. Morral, T. Dörk, R. Llevadot, Violetta Dziadek +8 more
1996Human Mutation65 citations
Semantic Scholar
Transcription releases protein VII from adenovirus chromatin.
Jiang-Ning Chen, N. Morral, D. Engel
2007Virology63 citations Open access
Semantic Scholar
ΔF508 GENE DELETION IN CYSTIC FIBROSIS IN SOUTHERN EUROPE
X. Estivill, T. Casals, N. Morral, M. Chillón +10 more
198962 citations
Semantic Scholar
Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the livers⃞ Published, JLR Papers in Press, April 21, 2007.
N. Morral, H. Edenberg, S. Witting, J. Altomonte +2 more
2007Journal of Lipid Research55 citations Open access
Semantic Scholar
Identical intragenic microsatellite haplotype found in cystic fibrosis chromosomes bearing mutation G551D in Irish, English, Scottish, Breton and Czech patients.
S. Cashman, A. Patiño, A. Martinez, M. García-Delgado +8 more
1995Human Heredity50 citations
Semantic Scholar
Gene therapy for age-related macular degeneration
Nicholas A Moore, P. Bracha, Rehan M. Hussain, N. Morral +1 more
2017Expert Opinion on Biological Therapy47 citations Open access
Semantic Scholar
Helper-dependent Adenovirus-mediated Short Hairpin RNA Expression in the Liver Activates the Interferon Response*
S. Witting, Matthew Brown, R. Saxena, S. Nabinger +1 more
2008Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Basal insulin gene expression significantly improves conventional insulin therapy in type 1 diabetic rats.
Heng-Jiang Dong, J. Altomonte, N. Morral, M. Meseck +2 more
2002Diabetes44 citations
Semantic Scholar
Independent origins of cystic fibrosis mutations R334W, R347P, R1162X, and 3849 + 10kbC-->T provide evidence of mutation recurrence in the CFTR gene.
N. Morral, R. Llevadot, T. Casals, P. Gasparini +3 more
1994American Journal of Human Genetics44 citations
Semantic Scholar
Adenovirus-Mediated Expression of Glucokinase in the Liver as an Adjuvant Treatment for Type 1 Diabetes
N. Morral, R. Mcevoy, Heng-Jiang Dong, M. Meseck +3 more
2002Human Gene Therapy42 citations
Semantic Scholar
Cystic fibrosis in a low-incidence population: two major mutations in Finland
J. Kere, X. Estivill, M. Chillón, N. Morral +4 more
1994Human Genetics38 citations
Semantic Scholar
Uniparental inheritance of microsatellite alleles of the cystic fibrosis gene (CFTR): identification of a 50 kilobase deletion.
N. Morral, V. Nunes, T. Casals, Nicolás Cobos +3 more
1993Human Molecular Genetics38 citations
Semantic Scholar
Comparative nucleic acid transfection efficacy in primary hepatocytes for gene silencing and functional studies
Jae-seung Park, Sneha Surendran, L. Kamendulis, N. Morral
2011BMC Research Notes36 citations Open access
Semantic Scholar
Analysis of the CFTR gene confirms the high genetic heterogeneity of the Spanish population: 43 mutations account for only 78% of CF chromosomes
M. Chillón, T. Casals, J. Giménez, M. Ramos +4 more
1994Human Genetics36 citations
Semantic Scholar
Cystic fibrosis in Spain: high frequency of mutation G542X in the Mediterranean coastal area
T. Casals, V. Nunes, A. Palacio, J. Giménez +4 more
1993Human Genetics33 citations
Semantic Scholar
CFTR haplotypic variability for normal and mutant genes in cystic fibrosis families from southern France
M. Claustres, M. Desgeorges, P. Moine, N. Morral +1 more
1996Human Genetics30 citations
Semantic Scholar
Accurate single-day titration of adenovirus vectors based on equivalence of protein VII nuclear dots and infectious particles
Marcin P. Walkiewicz, N. Morral, D. Engel
2009Journal of Virological Methods26 citations Open access
Semantic Scholar
Robust Hepatic Gene Silencing for Functional Studies Using Helper-Dependent Adenoviral Vectors
R. Ruíz, S. Witting, R. Saxena, N. Morral
2008Human Gene Therapy25 citations Open access
Semantic Scholar
Complete detection of mutations in cystic fibrosis patients of Native American origin
B. Mercier, O. Raguénès, X. Estivill, N. Morral +10 more
1994Human Genetics23 citations
Semantic Scholar
Role of non-coding RNAs on liver metabolism and NAFLD pathogenesis.
Ge-Ne Qian, N. Morral
2022Human Molecular Genetics21 citations
Semantic Scholar
Erratum: Haplotype analysis of 94 cystic fibrosis mutations with seven polymorphic CFTR DNA markers (Human Mutation (1996) 8 (149-159))
N. Morral, T. Dörk, R. Llevadot, Violetta Dziadek +8 more
199621 citations
Semantic Scholar
Aberrant gene expression induced by a high fat diet is linked to H3K9 acetylation in the promoter-proximal region
N. Morral, Sheng Liu, A. Conteh, Xiao-Na Chu +5 more
2021Biochimica et Biophysica Acta. Gene Regulatory Mechanisms20 citations Open access
Semantic Scholar
Analysis of microsatellites by direct blotting electrophoresis and chemiluminescence detection
F. Mekus, T. Dörk, T. Deufel, N. Morral +1 more
1995Electrophoresis18 citations
Semantic Scholar
Impact of silencing hepatic SREBP-1 on insulin signaling
V. Jideonwo, Yong-Yong Hou, M. Ahn, Sneha Surendran +1 more
2018PLoS ONE16 citations Open access
Semantic Scholar
Constitutive Expression of Short Hairpin RNA in Vivo Triggers Buildup of Mature Hairpin Molecules
M. Ahn, S. Witting, R. Ruíz, Romil Saxena +1 more
2011Human Gene Therapy16 citations Open access
Semantic Scholar
Prenatal diagnosis of cystic fibrosis by multiplex PCR of mutation and microsatellite alleles.
X. Estivill, N. Morral, T. Casals, V. Nunes
1991The Lancet15 citations
Semantic Scholar
Delta F508 gene deletion in cystic fibrosis in southern Europe [letter]
X. Estivill, M. Chillón, T. Casals, A. Bosch +6 more
198914 citations
Semantic Scholar
Gene targets of mouse miR-709: regulation of distinct pools
Sneha Surendran, V. Jideonwo, Chris Merchun, M. Ahn +5 more
2016Scientific Reports12 citations Open access
Semantic Scholar
Insights from a high-fat diet fed mouse model with a humanized liver
R. Saxena, M. Nassiri, Xiao-Ming Yin, N. Morral
2022PLoS ONE11 citations Open access
Semantic Scholar
Vector and Helper Genome Rearrangements Occur During Production of Helper-Dependent Adenoviral Vectors
M. Ahn, Aisha Gamble, S. Witting, Jack Magrisso +3 more
2012Human Gene Therapy Methods9 citations Open access
Semantic Scholar
Enhancing hepatic mitochondrial fatty acid oxidation stimulates eating in food-deprived mice.
A. Mansouri, Gustavo Pacheco-López, D. Ramachandran, M. Arnold +4 more
2015American Journal of Physiology. Regulatory Integrative and Comparative Physiology7 citations Open access
Semantic Scholar
shRNA-induced interferon-stimulated gene analysis.
N. Morral, S. Witting
2012Methods in molecular biology7 citations
Semantic Scholar
Improved glycemia by hepatic insulin gene expression in insulin-dependent diabetes mellitus
N. Morral, Heng-Jiang Dong, Robert MvEvoy, M. Meseck +1 more
20005 citations
Semantic Scholar
Reply to — Age of the ΔF508 cystic fibrosis mutation
X. Estivill, N. Morral, J. Bertranpetit
1994Nature Genetics5 citations
Semantic Scholar
Caracterització molecular de la FQ a la població espanyola Cystic fibrosis in the basque country: high frequency of mutation F508 in patients of basque origin
C. Vázquez, C. Lázaro, E. Girbau, F. Giménez +9 more
20052 citations
Semantic Scholar
Patterns of haplotypes for 92 cystic fibrosis mutations: Variability, association and recurrence
N. Morral, R. Llevadot, X. Estivill
19941 citations
Semantic Scholar
Hepatic microRNAs in Type II Diabetes Pathogenesis
G. Qian, N. Morral
2020Proceedings of IMPRS0 citations Open access
Semantic Scholar

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