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S. Cashman · SciRah

Researcher profile · Semantic Scholar

S. Cashman

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S. Cashman — researcher profile on SciRah

h-index: 23
Works: 66
Citations: 1,865

Most-cited papers

A mutation in CFTR produces different phenotypes depending on chromosomal background
S. Kiesewetter, M. Macek, C. Davis, S. Curristin +12 more
1993Nature Genetics480 citations
Semantic Scholar
Cell-penetrating peptide for enhanced delivery of nucleic acids and drugs to ocular tissues including retina and cornea.
L. N. Johnson, S. Cashman, R. Kumar-Singh
2008Molecular Therapy157 citations Open access
Semantic Scholar
A Non Membrane-Targeted Human Soluble CD59 Attenuates Choroidal Neovascularization in a Model of Age Related Macular Degeneration
S. Cashman, K. Ramo, R. Kumar-Singh
2011PLoS ONE121 citations Open access
Semantic Scholar
Cell Penetrating Peptide POD Mediates Delivery of Recombinant Proteins to Retina, Cornea and Skin
L. N. Johnson, S. Cashman, S. Read, R. Kumar-Singh
2009Vision Research73 citations Open access
Semantic Scholar
Intercellular trafficking of adenovirus-delivered HSV VP22 from the retinal pigment epithelium to the photoreceptors--implications for gene therapy.
S. Cashman, S. Sadowski, D. Morris, J. Frederick +1 more
2002Molecular Therapy71 citations Open access
Semantic Scholar
Inhibition of choroidal neovascularization by adenovirus-mediated delivery of short hairpin RNAs targeting VEGF as a potential therapy for AMD.
S. Cashman, Lisa Bowman, J. Christofferson, R. Kumar-Singh
2006Investigative Ophthalmology and Visual Science63 citations Open access
Semantic Scholar
POD nanoparticles expressing GDNF provide structural and functional rescue of light-induced retinal degeneration in an adult mouse.
S. Read, S. Cashman, R. Kumar-Singh
2010Molecular Therapy62 citations Open access
Semantic Scholar
Evidence of protein transduction but not intercellular transport by proteins fused to HIV tat in retinal cell culture and in vivo.
S. Cashman, D. Morris, R. Kumar-Singh
2003Molecular Therapy55 citations Open access
Semantic Scholar
Identical intragenic microsatellite haplotype found in cystic fibrosis chromosomes bearing mutation G551D in Irish, English, Scottish, Breton and Czech patients.
S. Cashman, A. Patiño, A. Martinez, M. García-Delgado +8 more
1995Human Heredity50 citations
Semantic Scholar
Expression of complement component 3 (C3) from an adenovirus leads to pathology in the murine retina.
S. Cashman, Akshata Desai, K. Ramo, R. Kumar-Singh
2011Investigative Ophthalmology and Visual Science49 citations
Semantic Scholar
Towards mutation-independent silencing of genes involved in retinal degeneration by RNA interference
S. Cashman, E. Binkley, R. Kumar-Singh
2005Gene Therapy45 citations Open access
Semantic Scholar
Identification of eight novel mutations in a collaborative analysis of a part of the second transmembrane domain of the CFTR gene.
B. Mercier, W. Lissens, G. Novelli, L. Kalaydjieva +17 more
1993Genomics45 citations Open access
Semantic Scholar
Adenovirus type 5 pseudotyped with adenovirus type 37 fiber uses sialic acid as a cellular receptor.
S. Cashman, D. Morris, R. Kumar-Singh
2004Virology44 citations Open access
Semantic Scholar
Evaluation of adenovirus-delivered human CD59 as a potential therapy for AMD in a model of human membrane attack complex formation on murine RPE.
K. Ramo, S. Cashman, R. Kumar-Singh
2008Investigative Ophthalmology and Visual Science43 citations Open access
Semantic Scholar
Complement-Mediated Activation of the NLRP3 Inflammasome and Its Inhibition by AAV-Mediated Delivery of CD59 in a Model of Uveitis.
B. Kumar, S. Cashman, R. Kumar-Singh
2018Molecular Therapy39 citations Open access
Semantic Scholar
A poly(ethylene) glycolylated peptide for ocular delivery compacts DNA into nanoparticles for gene delivery to post-mitotic tissues in vivo
S. Read, S. Cashman, R. Kumar-Singh
2010Journal of Gene Medicine35 citations Open access
Semantic Scholar
Adenovirus vectors targeting distinct cell types in the retina.
J. Sweigard, S. Cashman, R. Kumar-Singh
2010Investigative Ophthalmology and Visual Science35 citations Open access
Semantic Scholar
Adeno-Associated Virus Mediated Delivery of a Non-Membrane Targeted Human Soluble CD59 Attenuates Some Aspects of Diabetic Retinopathy in Mice
M. Adhi, S. Cashman, R. Kumar-Singh
2013PLoS ONE33 citations Open access
Semantic Scholar
Aurintricarboxylic acid inhibits complement activation, membrane attack complex, and choroidal neovascularization in a model of macular degeneration.
Erion Lipo, S. Cashman, R. Kumar-Singh
2013Investigative Ophthalmology and Visual Science33 citations Open access
Semantic Scholar
Improved retinal transduction in vivo and photoreceptor-specific transgene expression using adenovirus vectors with modified penton base.
S. Cashman, L. McCullough, R. Kumar-Singh
2007Molecular Therapy33 citations Open access
Semantic Scholar
The Irish cystic fibrosis database.
S. Cashman, Ana Patiño, M. Delgado, L. Byrne +2 more
1995Journal of Medical Genetics29 citations Open access
Semantic Scholar
Engineered zinc finger nuclease-mediated homologous recombination of the human rhodopsin gene.
D. Greenwald, S. Cashman, R. Kumar-Singh
2010Investigative Ophthalmology and Visual Science26 citations Open access
Semantic Scholar
Reducible PEG-POD/DNA Nanoparticles for Gene Transfer In Vitro and In Vivo: Application in a Mouse Model of Age-Related Macular Degeneration
B. Dasari, S. Cashman, R. Kumar-Singh
2017Molecular Therapy: Nucleic Acids23 citations Open access
Semantic Scholar
Deletion ΔF508 and clinical expression of cystic fibrosis‐related liver disease
M. Arce, S. O’Brien, J. Hegarty, S. M. O'Mahoney +4 more
199222 citations
Semantic Scholar
Adenovirus‐mediated delivery of Factor H attenuates complement C3 induced pathology in the murine retina: a potential gene therapy for age‐related macular degeneration
S. Cashman, Jessica Gracias, M. Adhi, R. Kumar-Singh
2015Journal of Gene Medicine21 citations
Semantic Scholar
Mutation Independent Rescue of a Novel Mouse Model of Retinitis Pigmentosa
D. Greenwald, S. Cashman, R. Kumar-Singh
2012Gene Therapy21 citations Open access
Semantic Scholar
Decay accelerating factor (CD55)-mediated attenuation of complement: therapeutic implications for age-related macular degeneration.
Kelly N. Ma, S. Cashman, J. Sweigard, R. Kumar-Singh
2010Investigative Ophthalmology and Visual Science20 citations Open access
Semantic Scholar
Topical Application of a G-Quartet Aptamer Targeting Nucleolin Attenuates Choroidal Neovascularization in a Model of Age-Related Macular Degeneration
D. Leaderer, S. Cashman, R. Kumar-Singh
2015Experimental Eye Research19 citations Open access
Semantic Scholar
Soluble CD59 Expressed from an Adenovirus In Vivo Is a Potent Inhibitor of Complement Deposition on Murine Liver Vascular Endothelium
Jarel K. Gandhi, S. Cashman, R. Kumar-Singh
2011PLoS ONE16 citations Open access
Semantic Scholar
Nuclear targeted delivery of macromolecules to retina and cornea
C. Binder, S. Read, S. Cashman, R. Kumar-Singh
2011Journal of Gene Medicine15 citations
Semantic Scholar
Adenovirus-mediated delivery of CD46 attenuates the alternative complement pathway on RPE: implications for age-related macular degeneration
J. Sweigard, S. Cashman, R. Kumar-Singh
2011Gene Therapy13 citations Open access
Semantic Scholar
G-quartet oligonucleotide mediated delivery of proteins into photoreceptors and retinal pigment epithelium via intravitreal injection
D. Leaderer, S. Cashman, R. Kumar-Singh
2016Experimental Eye Research12 citations Open access
Semantic Scholar
A cluster of cystic fibrosis mutations in exon 17b of the CFTR gene: a site for rare mutations.
B. Mercier, W. Lissens, G. Novelli, L. Kalaydjieva +6 more
1994Journal of Medical Genetics12 citations Open access
Semantic Scholar
Deletion delta F508 and clinical expression of cystic fibrosis-related liver disease.
M. D. de Arce, S. O’Brien, J. Hegarty, S. O’Mahoney +4 more
1992Clinical Genetics9 citations
Semantic Scholar
Extended Duration of Transgene Expression from Pegylated POD Nanoparticles Enables Attenuation of Photoreceptor Degeneration
C. Binder, S. Cashman, R. Kumar-Singh
2013PLoS ONE8 citations Open access
Semantic Scholar
Cell-Penetrating Chaperone Nuc1 for Small- and Large-Molecule Delivery Into Retinal Cells and Tissues
Binit Kumar, Manish Mishra, D. Talreja, S. Cashman +1 more
2024Investigative Ophthalmology and Visual Science7 citations Open access
Semantic Scholar
Adeno-Associated Virus Mediated Delivery of An Engineered Protein that Combines the Complement Inhibitory Properties of CD46, CD55 and CD59
D. Leaderer, S. Cashman, R. Kumar-Singh
2015Journal of Gene Medicine7 citations Open access
Semantic Scholar
G‐quartet oligonucleotide mediated delivery of functional X‐linked inhibitor of apoptosis protein into retinal cells following intravitreal injection
D. Talreja, S. Cashman, B. Dasari, B. Kumar +1 more
2018Experimental Eye Research6 citations Open access
Semantic Scholar
Retinal Penetrating Adeno-Associated Virus
Binit Kumar, Manish Mishra, S. Cashman, R. Kumar-Singh
2024Investigative Ophthalmology and Visual Science5 citations Open access
Semantic Scholar
AAV-IKV mediated expression of decorin inhibits EMT and fibrosis in a murine model of Glaucoma and AAV-IKV transduction in Non-Human Primates
Pushpa Rao, Manish Mishra, S. Cashman, David S. Walton +1 more
2025Scientific Reports4 citations Open access
Semantic Scholar
Increased Longevity of Rescue of Light-Induced Retinal Damage in an Adult Mouse Using Peptide for Ocular Delivery (POD) as a Gene Transfer Vector
R. Kumar-Singh, C. Binder, S. Cashman
20121 citations Open access
Semantic Scholar
POD DNA Nanoparticles Rescue an Adult Mouse Model of Retinal Degeneration
R. Kumar-Singh, S. Read, S. Cashman
20101 citations
Semantic Scholar
Novel Cell-Penetrating Peptide for Delivery of Nucleic Acids, Recombinant Proteins and Drugs to Ocular Tissues Including Retina and Cornea
L. N. Johnson, S. Cashman, R. Kumar-Singh
20081 citations Open access
Semantic Scholar
Mutation Independent Knock Down of Rhodopsin by Short Hairpin RNAs (shRNA) and Replacement by a shRNA–resistant Rhodopsin Transgene
R. Kumar-Singh, E. Binkley, S. Cashman
20041 citations
Semantic Scholar
Intravitreal AAV-IKV Mediated Delivery of Decorin Inhibits Choroidal Neovascularization, Fibrosis, Inflammation and Elevates Autophagy.
Manish Mishra, S. Cashman, R. Kumar-Singh
2025Experimental Eye Research0 citations
Semantic Scholar
Aptamer Mediated Protein Delivery to Retinal Cells
B. Dasari, D. Talreja, S. Cashman, R. Kumar-Singh
20180 citations
Semantic Scholar
Intravitreal Injection of Therapeutic Protein for Treatment of Retinal Degeneration
S. Cashman
2018Science trends0 citations Open access
Semantic Scholar
Complement Membrane Attack Complex activates the NLRP3 inflammasome in experimental autoimmune uveitis and inhibition by AAV mediated delivery of sCD59
B. Kumar, S. Cashman, R. Kumar-Singh
20180 citations
Semantic Scholar
Intravitreal Injection of Therapeutic Protein for Treatment of Retinal Degeneration
S. Cashman
20180 citations Open access
Semantic Scholar
Development of a platform protein delivery system for retinal cells in vivo following intravitreal injection
D. Talreja, S. Cashman, B. Dasari, R. Kumar-Singh
20180 citations
Semantic Scholar

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