L. Woodhouse

Most-cited papers

1. Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial

   Philip M Polly Craig S Jason P Evind Lesley Mark Timothy Bath Scutt Anderson Appleton Berge Cala Dixon Engl, P. Bath, Polly Scutt, C. Anderson +415 more

   2019The Lancet155 citations Open access

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2. Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial

   P. Bath, L. Woodhouse, J. Appleton, M. Beridze +18 more

   2018The Lancet148 citations Open access

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3. Imaging markers of small vessel disease and brain frailty, and outcomes in acute stroke

   J. Appleton, L. Woodhouse, A. Adami, Jennifer L. Becker +12 more

   2019Neurology131 citations Open access

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4. Isosorbide Mononitrate and Cilostazol Treatment in Patients With Symptomatic Cerebral Small Vessel Disease

   J. Wardlaw, L. Woodhouse, I. Mhlanga, K. Oatey +12 more

   2023JAMA Neurology126 citations Open access

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5. Early lowering of blood pressure after acute intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data

   T. Moullaali, Xia Wang, E. Sandset, L. Woodhouse +18 more

   2021Journal of Neurology Neurosurgery & Psychiatry68 citations Open access

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6. Noncontrast Computed Tomography Signs as Predictors of Hematoma Expansion, Clinical Outcome, and Response to Tranexamic Acid in Acute Intracerebral Hemorrhage

   Z. Law, Azlinawati Ali, K. Krishnan, A. Bischoff +15 more

   2019Stroke62 citations Open access

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7. Remote Ischemic Conditioning After Stroke Trial 2: A Phase IIb Randomized Controlled Trial in Hyperacute Stroke

   T. England, A. Hedstrom, S. O'Sullivan, L. Woodhouse +3 more

   2019Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease56 citations Open access

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8. Pharyngeal electrical stimulation for neurogenic dysphagia following stroke, traumatic brain injury or other causes: Main results from the PHADER cohort study

   P. Bath, L. Woodhouse, S. Suntrup-Krueger, R. Likar +18 more

   2020EClinicalMedicine44 citations Open access

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9. Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage

   P. Bath, L. Woodhouse, K. Krishnan, J. Appleton +23 more

   2019Stroke34 citations Open access

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10. Protocol: The Lacunar Intervention Trial 2 (LACI-2). A trial of two repurposed licenced drugs to prevent progression of cerebral small vessel disease

    J. Wardlaw, P. Bath, F. Doubal, A. Heye +9 more

    2020European Stroke Journal31 citations Open access

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11. Rates, risks and routes to reduce vascular dementia (R4vad), a UK-wide multicentre prospective observational cohort study of cognition after stroke: Protocol

    J. Wardlaw, F. Doubal, Rosalind Brown, E. Backhouse +14 more

    2020European Stroke Journal31 citations Open access

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12. Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: Rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053)

    J. Appleton, Polly Scutt, M. Dixon, Harriet Howard +10 more

    2019International Journal of Stroke31 citations Open access

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13. Influence of Time to Achieve Target Systolic Blood Pressure on Outcome After Intracerebral Hemorrhage: The Blood Pressure in Acute Stroke Collaboration

    Xia Wang, Jie Yang, T. Moullaali, E. Sandset +20 more

    2024Stroke26 citations Open access

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14. Desmopressin for patients with spontaneous intracerebral haemorrhage taking antiplatelet drugs (DASH): a UK-based, phase 2, randomised, placebo-controlled, multicentre feasibility trial

    M. Desborough, R. Al-Shahi Salman, S. Stanworth, D. Havard +19 more

    2023Lancet Neurology24 citations Open access

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15. Incidence and predictors of early seizures in intracerebral haemorrhage and the effect of tranexamic acid

    Z. Law, T. England, A. Mistri, L. Woodhouse +7 more

    2020European Stroke Journal24 citations Open access

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16. Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage Data From the RIGHT-2 Trial

    P. Bath, L. Woodhouse, K. Krishnan, J. Appleton +23 more

    201924 citations

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17. Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT.

    N. Sprigg, K. Flaherty, J. Appleton, R. Al-Shahi Salman +25 more

    2019Health Technology Assessment23 citations Open access

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18. Prevention of infections and fever to improve outcome in older patients with acute stroke (PRECIOUS): a randomised, open, phase III, multifactorial, clinical trial with blinded outcome assessment

    J. D. de Jonge, W. M. Sluis, Hendrik Reinink, Philip M. W. Bath +75 more

    2023The Lancet Regional Health - Europe22 citations Open access

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19. Effect of continuing versus stopping pre-stroke antihypertensive agents within 12 h on outcome after stroke: A subgroup analysis of the efficacy of nitric oxide in stroke (ENOS) trial

    L. Woodhouse, J. Appleton, Polly Scutt, L. Everton +15 more

    2022EClinicalMedicine21 citations Open access

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20. Continuing or Temporarily Stopping Prestroke Antihypertensive Medication in Acute Stroke: An Individual Patient Data Meta-Analysis

    L. Woodhouse, L. Manning, J. Potter, E. Berge +5 more

    2017HYPERTENSION18 citations Open access

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21. Statistical analysis plan for the ‘Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)’

    Polly Scutt, J. Appleton, M. Dixon, L. Woodhouse +5 more

    2018European Stroke Journal17 citations Open access

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22. Effect of Tranexamic Acid Administration on Remote Cerebral Ischemic Lesions in Acute Spontaneous Intracerebral Hemorrhage: A Substudy of a Randomized Clinical Trial.

    S. Pszczólkowski, N. Sprigg, L. Woodhouse, R. Gallagher +10 more

    2022JAMA Neurology15 citations Open access

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23. Baseline characteristics of the 1149 patients recruited into the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) randomized controlled trial

    P. Bath, Polly Scutt, J. Appleton, M. Dixon +3 more

    2018International Journal of Stroke15 citations Open access

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24. Ninety‐Day Stroke Recurrence in Minor Stroke: Systematic Review and Meta‐Analysis of Trials and Observational Studies

    A. Lim, Henry H Ma, S. C. Johnston, Shaloo Singhal +11 more

    2024Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease14 citations Open access

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25. Remote Assessment of Platelet Function in Patients with Acute Stroke or Transient Ischaemic Attack

    P. Bath, J. May, K. Flaherty, L. Woodhouse +8 more

    2017Stroke Research and Treatment14 citations Open access

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26. Triple versus guideline antiplatelet therapy to prevent recurrence after acute ischaemic stroke or transient ischaemic attack: the TARDIS RCT.

    P. Bath, L. Woodhouse, J. Appleton, M. Beridze +19 more

    2018Health Technology Assessment13 citations Open access

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27. Effects of Isosorbide Mononitrate and/or Cilostazol on Hematological Markers, Platelet Function, and Hemodynamics in Patients With Lacunar Ischaemic Stroke: Safety Data From the Lacunar Intervention-1 (LACI-1) Trial

    J. Appleton, Gordon W. Blair, K. Flaherty, Z. Law +6 more

    2019Frontiers in Neurology11 citations Open access

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28. Lowering blood pressure after acute intracerebral haemorrhage: protocol for a systematic review and meta-analysis using individual patient data from randomised controlled trials participating in the Blood Pressure in Acute Stroke Collaboration (BASC)

    T. Moullaali, Xia Wang, L. Woodhouse, Z. Law +10 more

    2019BMJ Open10 citations Open access

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29. Pre-hospital transdermal glyceryl trinitrate in patients with stroke mimics: data from the RIGHT-2 randomised-controlled ambulance trial

    B. Tunnage, L. Woodhouse, M. Dixon, C. Anderson +20 more

    2021BMC Emergency Medicine9 citations Open access

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30. Tranexamic Acid Within 4.5 Hours of Intracerebral Hemorrhage With the CTA Spot Sign

    N. Yassi, V. Yogendrakumar, Leonid Churilov, A. Meretoja +17 more

    2024Neurology8 citations Open access

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31. Prehospital transdermal glyceryl trinitrate for ultra-acute ischaemic stroke: data from the RIGHT-2 randomised sham-controlled ambulance trial

    J. Appleton, L. Woodhouse, C. Anderson, Sandeep Ankolekar +18 more

    2023Stroke and vascular neurology8 citations Open access

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32. Data sharing: experience of accessing individual patient data from completed randomised controlled trials in vascular and cognitive medicine

    Polly Scutt, L. Woodhouse, A. Montgomery, P. Bath

    2020BMJ Open8 citations Open access

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33. Central adjudication of serious adverse events did not affect trial’s safety results: Data from the Efficacy of Nitric Oxide in Stroke (ENOS) trial

    P. Godolphin, A. Montgomery, L. Woodhouse, D. Bereczki +13 more

    2018PLoS ONE8 citations Open access

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34. Baseline characteristics of the 3096 patients recruited into the ‘Triple Antiplatelets for Reducing Dependency after Ischemic Stroke’ trial

    P. Bath, J. Appleton, M. Beridze, H. Christensen +15 more

    2017International Journal of Stroke8 citations Open access

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35. Cilostazol and isosorbide mononitrate for the prevention of progression of cerebral small vessel disease: baseline data and statistical analysis plan for the Lacunar Intervention Trial-2 (LACI-2) (ISRCTN14911850)

    P. Bath, I. Mhlanga, L. Woodhouse, F. Doubal +3 more

    2022medRxiv7 citations Open access

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36. Statistical reanalysis of vascular event outcomes in primary and secondary vascular prevention trials

    L. Woodhouse, A. Montgomery, J. Mant, B. Davis +15 more

    2021BMC Medical Research Methodology7 citations Open access

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37. Cost-benefit of outcome adjudication in nine randomised stroke trials

    P. Godolphin, P. Bath, A. Algra, E. Berge +8 more

    2020Clinical Trials7 citations Open access

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38. PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke—statistical analysis plan of a randomised, open, phase III, clinical trial with blinded outcome assessment

    J. D. de Jonge, L. Woodhouse, Hendrik Reinink, H. Bart van der Worp +2 more

    2020Trials7 citations Open access

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39. It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis

    J. Appleton, L. Woodhouse, Andrew Belcher, D. Bereczki +15 more

    2019Stroke and vascular neurology7 citations Open access

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40. Effect of Glyceryl Trinitrate on Hemodynamics in Acute Stroke

    J. Appleton, L. Woodhouse, D. Bereczki, E. Berge +10 more

    2019Stroke7 citations Open access

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41. Impact of ultra/hyper-acute administration of glyceryl trinitrate on secondary outcome after acute stroke: a meta-analysis of individual patient data from randomised trials

    P. Bath, L. Woodhouse, N. Sprigg

    20187 citations

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42. Metoclopramide to Prevent Pneumonia in Patients With Stroke and a Nasogastric Tube: Data From the PRECIOUS Trial

    W. M. Sluis, J. D. de Jonge, Hendrik Reinink, L. Woodhouse +5 more

    2024Stroke6 citations Open access

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43. Time intervals and distances travelled for prehospital ambulance stroke care: data from the randomised-controlled ambulance-based Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)

    M. Dixon, J. Appleton, Polly Scutt, L. Woodhouse +5 more

    2022BMJ Open6 citations Open access

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44. Protocol for a prospective collaborative systematic review and meta-analysis of individual patient data from randomized controlled trials of vasoactive drugs in acute stroke: The Blood pressure in Acute Stroke Collaboration, stage-3

    E. Sandset, N. Sanossian, L. Woodhouse, C. S. Anderson +7 more

    2018International Journal of Stroke6 citations Open access

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45. Design of trials in lacunar stroke and cerebral small vessel disease: review and experience with the LACunar Intervention Trial 2 (LACI-2)

    Gordon W. Blair, J. Appleton, I. Mhlanga, L. Woodhouse +3 more

    2024Stroke and vascular neurology5 citations Open access

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46. Outcome 1 year after ICH: Data from the Tranexamic acid for IntraCerebral Haemorrhage 2 (TICH-2) trial

    Z. Law, C. S. Menon, L. Woodhouse, J. Appleton +7 more

    2024European Stroke Journal5 citations Open access

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47. Relationship between nitrate headache and outcome in patients with acute stroke: results from the efficacy of nitric oxide in stroke (ENOS) trial

    Lucy Beishon, L. Woodhouse, D. Bereczki, Hanne Christensen +11 more

    2020Stroke and vascular neurology5 citations Open access

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48. Mannitol for cerebral oedema after acute intracerebral haemorrhage (MACE-ICH): protocol for a prospective, randomised, open-label, blinded-endpoint phase IIb trial

    K. Krishnan, Emma Grace, L. Woodhouse, C. Roffe +15 more

    2025BMJ Open4 citations Open access

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49. The Effect of Tranexamic Acid on Neurosurgical Intervention in Spontaneous Intracerebral Hematoma: Data From 121 Surgically Treated Participants From the Tranexamic Acid in IntraCerebral Hemorrhage-2 Randomized Controlled Trial

    M. Hollingworth, L. Woodhouse, Z. Law, Azlinawati Ali +15 more

    2024Neurosurgery4 citations Open access

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50. Associations between change in blood pressure and functional outcome, early events and death: results from the Efficacy of Nitric Oxide in Stroke trial

    E. Sandset, J. Appleton, E. Berge, H. Christensen +8 more

    2019Journal of Hypertension4 citations Open access

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