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N. Sprigg · SciRah

Researcher profile · Semantic Scholar

N. Sprigg

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N. Sprigg — researcher profile on SciRah

h-index: 45
Works: 263
Citations: 8,424

Most-cited papers

2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association.
S. Greenberg, W. Ziai, C. Cordonnier, D. Dowlatshahi +15 more
2022Stroke1,186 citations Open access
Semantic Scholar
The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial
Lu Ma, Xin Hu, Li-Li Song, Xiao-Ying Chen +496 more
2023The Lancet288 citations Open access
Semantic Scholar
Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies
D. Wilson, G. Ambler, K. Lee, Jae-Sung Lim +306 more
2019Lancet Neurology161 citations Open access
Semantic Scholar
Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial
Philip M Polly Craig S Jason P Evind Lesley Mark Timothy Bath Scutt Anderson Appleton Berge Cala Dixon Engl, P. Bath, Polly Scutt, C. Anderson +415 more
2019The Lancet155 citations Open access
Semantic Scholar
Intracerebral implantation of human neural stem cells and motor recovery after stroke: multicentre prospective single-arm study (PISCES-2)
K. Muir, D. Bulters, M. Willmot, N. Sprigg +10 more
2020Journal of Neurology Neurosurgery & Psychiatry143 citations Open access
Semantic Scholar
Imaging markers of small vessel disease and brain frailty, and outcomes in acute stroke
J. Appleton, L. Woodhouse, A. Adami, Jennifer L. Becker +12 more
2019Neurology131 citations Open access
Semantic Scholar
Isosorbide Mononitrate and Cilostazol Treatment in Patients With Symptomatic Cerebral Small Vessel Disease
J. Wardlaw, L. Woodhouse, I. Mhlanga, K. Oatey +12 more
2023JAMA Neurology126 citations Open access
Semantic Scholar
Early lowering of blood pressure after acute intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data
T. Moullaali, Xia Wang, E. Sandset, L. Woodhouse +18 more
2021Journal of Neurology Neurosurgery & Psychiatry68 citations Open access
Semantic Scholar
The Story of Intracerebral Hemorrhage: From Recalcitrant to Treatable Disease
J. Broderick, J. Grotta, A. Naidech, T. Steiner +7 more
2021Stroke67 citations Open access
Semantic Scholar
Therapeutic hypothermia for acute ischaemic stroke. Results of a European multicentre, randomised, phase III clinical trial
H. Bart van der Worp, M. Macleod, P. Bath, R. Bathula +24 more
2019European Stroke Journal66 citations Open access
Semantic Scholar
Noncontrast Computed Tomography Signs as Predictors of Hematoma Expansion, Clinical Outcome, and Response to Tranexamic Acid in Acute Intracerebral Hemorrhage
Z. Law, Azlinawati Ali, K. Krishnan, A. Bischoff +15 more
2019Stroke62 citations Open access
Semantic Scholar
Perfusion Imaging for Endovascular Thrombectomy in Acute Ischemic Stroke Is Associated With Improved Functional Outcomes in the Early and Late Time Windows
P. Dhillon, Waleed Z. Butt, A. Podlasek, N. McConachie +25 more
2022Stroke57 citations Open access
Semantic Scholar
Quantitative CT radiomics-based models for prediction of haematoma expansion and poor functional outcome in primary intracerebral haemorrhage
S. Pszczólkowski, J. Manzano-Patron, Z. Law, K. Krishnan +4 more
2021European Radiology57 citations Open access
Semantic Scholar
Recombinant Factor VIIa for Hemorrhagic Stroke Treatment at Earliest Possible Time (FASTEST): Protocol for a Phase III, Double-Blind, Randomized, Placebo-Controlled Trial
A. Naidech, J. Grotta, J. Elm, Scott Janis +12 more
2021International Journal of Stroke55 citations
Semantic Scholar
Delirium as a presenting feature in COVID-19: Neuroinvasive infection or autoimmune encephalopathy?
A. Hosseini, Ashita Shetty, N. Sprigg, D. Auer +1 more
2020Brain, behavior, and immunity54 citations Open access
Semantic Scholar
Predictors and Outcomes of Neurological Deterioration in Intracerebral Hemorrhage: Results from the TICH-2 Randomized Controlled Trial
Z. Law, R. Dineen, T. England, L. Cala +7 more
2020Translational Stroke Research48 citations Open access
Semantic Scholar
Tolerability, safety and intermediary pharmacological effects of cilostazol and isosorbide mononitrate, alone and combined, in patients with lacunar ischaemic stroke: The LACunar Intervention-1 (LACI-1) trial, a randomised clinical trial
Gordon W. Blair, J. Appleton, K. Flaherty, F. Doubal +12 more
2019EClinicalMedicine47 citations Open access
Semantic Scholar
Optimal timing of anticoagulation after acute ischemic stroke with atrial fibrillation (OPTIMAS): Protocol for a randomized controlled trial
J. Best, Liz Arram, N. Ahmed, Maryam Balogun +20 more
2022International Journal of Stroke45 citations Open access
Semantic Scholar
Recommendations for Clinical Trials in ICH: The Second HEmorrhagic stroke Academia inDuStry (HEADS) Roundtable
M. Selim, D. Hanley, T. Steiner, H. Christensen +34 more
2020Stroke45 citations Open access
Semantic Scholar
Antiplatelet Resistance: A Review of Concepts, Mechanisms, and Implications for Management in Acute Ischemic Stroke and Transient Ischemic Attack
K. Krishnan, Thanh N. Nguyen, J. Appleton, Z. Law +18 more
2023Stroke40 citations Open access
Semantic Scholar
Semantic Segmentation of Spontaneous Intracerebral Hemorrhage, Intraventricular Hemorrhage, and Associated Edema on CT Images Using Deep Learning.
Yong-En Kok, S. Pszczólkowski, Z. Law, Azlinawati Ali +5 more
2022Radiology: Artificial Intelligence40 citations Open access
Semantic Scholar
Tranexamic Acid for Intracerebral Hemorrhage in Patients on Non-Vitamin K Antagonist Oral Anticoagulants (TICH-NOAC): A Multicenter, Randomized, Placebo-Controlled, Phase 2 Trial
A. Polymeris, G. Karwacki, B. Siepen, S. Schaedelin +24 more
2023Stroke34 citations Open access
Semantic Scholar
Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage
P. Bath, L. Woodhouse, K. Krishnan, J. Appleton +23 more
2019Stroke34 citations Open access
Semantic Scholar
Safety and efficacy of GABAA α5 antagonist S44819 in patients with ischaemic stroke: a multicentre, double-blind, randomised, placebo-controlled trial.
H. Chabriat, C. Bassetti, U. Marx, Marie-Laure Audoli-Inthavong +98 more
2020Lancet Neurology33 citations Open access
Semantic Scholar
External Validation of e‐ASPECTS Software for Interpreting Brain CT in Stroke
Grant Mair, P. White, P. Bath, K. Muir +9 more
2022Annals of Neurology32 citations Open access
Semantic Scholar
Protocol: The Lacunar Intervention Trial 2 (LACI-2). A trial of two repurposed licenced drugs to prevent progression of cerebral small vessel disease
J. Wardlaw, P. Bath, F. Doubal, A. Heye +9 more
2020European Stroke Journal31 citations Open access
Semantic Scholar
Rates, risks and routes to reduce vascular dementia (R4vad), a UK-wide multicentre prospective observational cohort study of cognition after stroke: Protocol
J. Wardlaw, F. Doubal, Rosalind Brown, E. Backhouse +14 more
2020European Stroke Journal31 citations Open access
Semantic Scholar
Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: Rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053)
J. Appleton, Polly Scutt, M. Dixon, Harriet Howard +10 more
2019International Journal of Stroke31 citations Open access
Semantic Scholar
How do stroke survivors and their caregivers manage post-stroke fatigue? A qualitative study
J. Ablewhite, F. Nouri, Alice Whisker, Shirley A. Thomas +6 more
2022Clinical Rehabilitation28 citations Open access
Semantic Scholar
Inhibition of oxidative stress delays senescence and augments functional capacity of endothelial progenitor cells.
R. Kadir, Mansour Alwjwaj, Othman Ahmad Othman, Kamini Rakkar +3 more
2022Brain Research27 citations Open access
Semantic Scholar
Desmopressin for patients with spontaneous intracerebral haemorrhage taking antiplatelet drugs (DASH): a UK-based, phase 2, randomised, placebo-controlled, multicentre feasibility trial
M. Desborough, R. Al-Shahi Salman, S. Stanworth, D. Havard +19 more
2023Lancet Neurology24 citations Open access
Semantic Scholar
Incidence and predictors of early seizures in intracerebral haemorrhage and the effect of tranexamic acid
Z. Law, T. England, A. Mistri, L. Woodhouse +7 more
2020European Stroke Journal24 citations Open access
Semantic Scholar
Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT.
N. Sprigg, K. Flaherty, J. Appleton, R. Al-Shahi Salman +25 more
2019Health Technology Assessment23 citations Open access
Semantic Scholar
Endothelial progenitor cells, potential biomarkers for diagnosis and prognosis of ischemic stroke: protocol for an observational case-control study
Kamini Rakkar, O. Othman, N. Sprigg, P. Bath +1 more
2020Neural Regeneration Research22 citations Open access
Semantic Scholar
Effect of continuing versus stopping pre-stroke antihypertensive agents within 12 h on outcome after stroke: A subgroup analysis of the efficacy of nitric oxide in stroke (ENOS) trial
L. Woodhouse, J. Appleton, Polly Scutt, L. Everton +15 more
2022EClinicalMedicine21 citations Open access
Semantic Scholar
Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign
Christian Ovesen, J. Jakobsen, C. Gluud, T. Steiner +9 more
2021Stroke21 citations Open access
Semantic Scholar
Association between time to treatment and clinical outcomes in endovascular thrombectomy beyond 6 hours without advanced imaging selection
P. Dhillon, Waleed Z. Butt, A. Podlasek, N. McConachie +16 more
2022Journal of NeuroInterventional Surgery20 citations Open access
Semantic Scholar
Automated detection of cerebral microbleeds on MR images using knowledge distillation framework
Vaanathi Sundaresan, C. Arthofer, G. Zamboni, A. Murchison +11 more
2021medRxiv20 citations Open access
Semantic Scholar
Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage.
Helle Eilertsen, C. S. Menon, Z. Law, Chen Chen +6 more
2023Cochrane Database of Systematic Reviews17 citations Open access
Semantic Scholar
Cerebral Amyloid Angiopathy and the Risk of Hematoma Expansion
D. Seiffge, A. Polymeris, Z. Law, K. Krishnan +10 more
2022Annals of Neurology17 citations Open access
Semantic Scholar
Pressor therapy in acute ischaemic stroke: an updated systematic review
T. Strømsnes, Truls Jørgen Kaugerud Hagen, M. Ouyang, Xia Wang +16 more
2022European Stroke Journal17 citations Open access
Semantic Scholar
Managing post-stroke fatigue: A qualitative study to explore multifaceted clinical perspectives
A. Drummond, F. Nouri, J. Ablewhite, L. Condon +5 more
2021British Journal of Occupational Therapy17 citations Open access
Semantic Scholar
Effect of Tranexamic Acid Administration on Remote Cerebral Ischemic Lesions in Acute Spontaneous Intracerebral Hemorrhage: A Substudy of a Randomized Clinical Trial.
S. Pszczólkowski, N. Sprigg, L. Woodhouse, R. Gallagher +10 more
2022JAMA Neurology15 citations Open access
Semantic Scholar
A scoping review of psychoeducational interventions for people after transient ischemic attack and minor stroke
E. Kontou, J. Kettlewell, L. Condon, Shirley A. Thomas +5 more
2020Topics in Stroke Rehabilitation15 citations Open access
Semantic Scholar
Intracerebral haemorrhage volume, haematoma expansion and 3-month outcomes in patients on antiplatelets. A systematic review and meta-analysis
M. Goeldlin, B. Siepen, MD Mueller, B. Volbers +6 more
2021European Stroke Journal14 citations Open access
Semantic Scholar
Accuracy of artificial intelligence software for CT angiography in stroke
Grant Mair, P. White, P. Bath, K. Muir +7 more
2023Annals of Clinical and Translational Neurology13 citations Open access
Semantic Scholar
Biopsychosocial intervention for stroke carers (BISC): results of a feasibility randomised controlled trial and nested qualitative interview study
M. Walker, S. Birchall, C. Cobley, L. Condon +9 more
2020Clinical Rehabilitation12 citations Open access
Semantic Scholar
Desmopressin for reversal of Antiplatelet drugs in Stroke due to Haemorrhage (DASH): protocol for a phase II double-blind randomised controlled feasibility trial
M. Desborough, R. Al-Shahi Salman, S. Stanworth, D. Havard +6 more
2020BMJ Open11 citations Open access
Semantic Scholar
Blood markers in remote ischaemic conditioning for acute ischaemic stroke: data from the REmote ischaemic Conditioning After Stroke Trial
J. Appleton, S. O'Sullivan, A. Hedstrom, J. May +4 more
2020European Journal of Neurology11 citations Open access
Semantic Scholar
Effects of Isosorbide Mononitrate and/or Cilostazol on Hematological Markers, Platelet Function, and Hemodynamics in Patients With Lacunar Ischaemic Stroke: Safety Data From the Lacunar Intervention-1 (LACI-1) Trial
J. Appleton, Gordon W. Blair, K. Flaherty, Z. Law +6 more
2019Frontiers in Neurology11 citations Open access
Semantic Scholar

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