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A. Higuchi · SciRah

Researcher profile · Semantic Scholar

A. Higuchi

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A. Higuchi — researcher profile on SciRah

h-index: 24
Works: 49
Citations: 3,921

Most-cited papers

Increased dietary intake of ω-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis
Kip M. Connor, J. Sangiovanni, Chatarina Lofqvist, C. Aderman +12 more
2007Nature Medicine732 citations Open access
Semantic Scholar
Adiponectin Promotes Macrophage Polarization toward an Anti-inflammatory Phenotype*
K. Ohashi, J. L. Parker, N. Ouchi, A. Higuchi +8 more
2009Journal of Biological Chemistry634 citations Open access
Semantic Scholar
Sfrp5 Is an Anti-Inflammatory Adipokine That Modulates Metabolic Dysfunction in Obesity
N. Ouchi, A. Higuchi, K. Ohashi, Yuichi Oshima +5 more
2010Science495 citations Open access
Semantic Scholar
Follistatin-like 1, a Secreted Muscle Protein, Promotes Endothelial Cell Function and Revascularization in Ischemic Tissue through a Nitric-oxide Synthase-dependent Mechanism*
N. Ouchi, Yuichi Oshima, K. Ohashi, A. Higuchi +3 more
2008Journal of Biological Chemistry330 citations Open access
Semantic Scholar
Adiponectin Prevents Cerebral Ischemic Injury Through Endothelial Nitric Oxide Synthase–Dependent Mechanisms
M. Nishimura, Y. Izumiya, A. Higuchi, R. Shibata +5 more
2008Circulation206 citations Open access
Semantic Scholar
Adipolin/C1qdc2/CTRP12 Protein Functions as an Adipokine That Improves Glucose Metabolism*
Takashi Enomoto, K. Ohashi, R. Shibata, A. Higuchi +5 more
2011Journal of Biological Chemistry149 citations Open access
Semantic Scholar
Cardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overload
M. Shimano, N. Ouchi, Kazuto Nakamura, B. van Wijk +8 more
2011Proceedings of the National Academy of Sciences of the United States of America146 citations Open access
Semantic Scholar
Omentin as a novel biomarker of metabolic risk factors
R. Shibata, N. Ouchi, Ryotaro Takahashi, Yuya Terakura +6 more
2012Diabetology & Metabolic Syndrome140 citations Open access
Semantic Scholar
DIP2A Functions as a FSTL1 Receptor*
N. Ouchi, Y. Asaumi, K. Ohashi, A. Higuchi +3 more
2010Journal of Biological Chemistry126 citations Open access
Semantic Scholar
The Polyphenols Resveratrol and S17834 prevent the Structural and Functional Sequelae of Diet-Induced Metabolic Heart Disease in Mice
Fu-Zhong Qin, D. Siwik, I. Luptak, Xiu-Yun Hou +11 more
2012Circulation124 citations Open access
Semantic Scholar
Adiponectin deficiency, diastolic dysfunction, and diastolic heart failure.
F. Sam, Toni-Ann S. Duhaney, Kaori Sato, Richard M. Wilson +7 more
2010Endocrinology92 citations Open access
Semantic Scholar
Adiponectin Promotes Revascularization of Ischemic Muscle through a Cyclooxygenase 2-Dependent Mechanism
K. Ohashi, N. Ouchi, Kaori Sato, A. Higuchi +4 more
2009Molecular and Cellular Biology88 citations Open access
Semantic Scholar
Adiponectin Suppresses Pathological Microvessel Formation in Retina Through Modulation of Tumor Necrosis Factor-α Expression
A. Higuchi, K. Ohashi, S. Kihara, K. Walsh +1 more
2009Circulation Research81 citations Open access
Semantic Scholar
Plasma concentration of pigment epithelium-derived factor in patients with diabetic retinopathy.
N. Ogata, M. Matsuoka, K. Matsuyama, C. Shima +9 more
2007Journal of Clinical Endocrinology and Metabolism81 citations Open access
Semantic Scholar
Adiponectin upregulates hepatocyte CMKLR1 which is reduced in human fatty liver
Josef Wanninger, S. Bauer, Kristina Eisinger, T. Weiss +6 more
2011Molecular and Cellular Endocrinology64 citations Open access
Semantic Scholar
Thiazolidinediones reduce pathological neovascularization in ischemic retina via an adiponectin-dependent mechanism
A. Higuchi, K. Ohashi, R. Shibata, Saki Sono-Romanelli +2 more
2009Arteriosclerosis, Thrombosis and Vascular Biology54 citations Open access
Semantic Scholar
Choroidal Neovascularization Is Provided by Bone Marrow Cells
M. Tomita, Haruhiko Yamada, Y. Adachi, Yun-Ze Cui +6 more
2004Stem Cells50 citations
Semantic Scholar
LKB1 Deficiency in Tie2-Cre-expressing Cells Impairs Ischemia-induced Angiogenesis*
K. Ohashi, N. Ouchi, A. Higuchi, R. Shaw +1 more
2010Journal of Biological Chemistry48 citations Open access
Semantic Scholar
Cardiac Myocyte-specific Ablation of Follistatin-like 3 Attenuates Stress-induced Myocardial Hypertrophy*
M. Shimano, N. Ouchi, Kazuto Nakamura, Yuichi Oshima +7 more
2011Journal of Biological Chemistry44 citations Open access
Semantic Scholar
High levels of pigment epithelium-derived factor in the retina of a rat model of type 2 diabetes.
M. Matsuoka, N. Ogata, K. Minamino, A. Higuchi +1 more
2006Experimental Eye Research44 citations
Semantic Scholar
Retinal neovascularisation without ischaemia in the spontaneously diabetic Torii rat
H. Yamada, E. Yamada, A. Higuchi, M. Matsumura
2005Diabetologia42 citations Open access
Semantic Scholar
Increased Ocular Levels of MicroRNA-148a in Cases of Retinal Detachment Promote Epithelial-Mesenchymal Transition.
K. Takayama, H. Kaneko, Shiang-Jyi Hwang, Fu-Xiang Ye +10 more
2016Investigative Ophthalmology and Visual Science32 citations Open access
Semantic Scholar
Long-term survival of bone marrow-derived retinal nerve cells in the retina
K. Minamino, Y. Adachi, Haruhiko Yamada, A. Higuchi +9 more
2005NeuroReport26 citations
Semantic Scholar
Role of Caveolin-1 for Blocking the Epithelial-Mesenchymal Transition in Proliferative Vitreoretinopathy.
Yosuke Nagasaka, H. Kaneko, Fu-Xiang Ye, S. Kachi +11 more
2017Investigative Ophthalmology and Visual Science25 citations Open access
Semantic Scholar
Histamine H4 receptor as a new therapeutic target for choroidal neovascularization in age‐related macular degeneration
H. Kaneko, Fu-Xiang Ye, R. Ijima, S. Kachi +4 more
2014British Journal of Pharmacology21 citations Open access
Semantic Scholar
Hypericin inhibits pathological retinal neovascularization in a mouse model of oxygen-induced retinopathy
A. Higuchi, Haruhiko Yamada, E. Yamada, N. Jo +1 more
2008Molecular Vision19 citations
Semantic Scholar
Trans-Tenon's Retrobulbar Injection of Triamcinolone Acetonide for Diffuse Diabetic Macular Edema
M. Wada, N. Ogata, K. Minamino, Masataka Koriyama +2 more
2005Japanese Journal of Ophthalmology16 citations
Semantic Scholar
Pars Plana Vitrectomy with Removal of Posterior Hyaloid Face in Treatment of Refractory Diabetic Macular Edema Resistant to Triamcinolone Acetonide
A. Higuchi, N. Ogata, N. Jo, M. Wada +1 more
2006Japanese Journal of Ophthalmology14 citations
Semantic Scholar
Histamine Receptor H4 as a New Therapeutic Target for Choroidal Neovascularization in Age-related Macular Degeneration
Fu-Xiang Ye, H. Kaneko, R. Ijima, S. Kachi +4 more
20146 citations
Semantic Scholar
Inhibitory Effect of Hypericin on Retinal and Choroidal Neovascularization
A. Higuchi, H. Yamada, E. Yamada, M. Matsumura
20034 citations
Semantic Scholar
BRIEF REPORT Plasma Concentration of Pigment Epithelium-Derived Factor in Patients with Diabetic Retinopathy
N. Ogata, M. Matsuoka, K. Matsuyama, C. Shima +9 more
20071 citations
Semantic Scholar
[Vitrectomy for proliferative diabetic retinopathy].
A. Higuchi, Haruhiko Yamada, Emi Kawai, Y. Fujiseki +5 more
2005Nippon Ganka Gakkai zasshi1 citations
Semantic Scholar
Corrigendum to “Adiponectin upregulates hepatocyte CMKLR1 which is reduced in human fatty liver” [Molecular and Cellular Endocrinology 349 (2012) 248–254]
Josef Wanninger, S. Bauer, Kristina Eisinger, T. Weiss +6 more
20120 citations
Semantic Scholar
Heart Failure The Polyphenols Resveratrol and S 17834 Prevent the Structural and Functional Sequelae of Diet-Induced Metabolic Heart Disease in Mice
Fu-Zhong Qin, D. Siwik, I. Luptak, Xiu-Yun Hou +11 more
20120 citations
Semantic Scholar
糖代謝を改善するアディポカインのようなアディポリン/C1qdc2/CTRP12のタンパク質機能 | 文献情報 | J-GLOBAL 科学技術総合リンクセンター
Takashi Enomoto, K. Ohashi, R. Shibata, A. Higuchi +5 more
20110 citations
Semantic Scholar
糖代謝を改善するアディポカインのようなアディポリン/C1qdc2/CTRP12のタンパク質機能
Takashi Enomoto, K. Ohashi, R. Shibata, A. Higuchi +5 more
20110 citations
Semantic Scholar
Bioactive -3 LCPUFA Derivatives, Resolvins and Neuroprotectins, Inhibit Neovascularization in Oxygen Induced Retinopathy
C. Aderman, Kip M. Connor, Jing Chen, A. Higuchi +5 more
20070 citations
Semantic Scholar
Protective Effect Against Retinal Neovascularization in Diabetic Retinopathy by Angiotensin Converting Enzyme Inhibitors
H. Yamada, A. Higuchi, N. Jo, M. Matsumura +3 more
20070 citations
Semantic Scholar
Omega-3 Long-Chain Polyunsaturated Fatty Acids (LCPUFAs) Suppress Retinal COX-2 mRNA and Retinal Neovascularization
A. Higuchi, Kip M. Connor, C. Aderman, Jing Chen +5 more
20070 citations
Semantic Scholar
Dietary -3 Long-Chain Polyunsaturated Fatty Acids Protect Against Pathological Retinal Neovascularization Through Modulation of Microglial Derived TNF-
Kip M. Connor, C. Aderman, Jin Chen, A. Higuchi +5 more
20070 citations
Semantic Scholar
Erythropoietin Protects Retina From Pathological Vessel Loss and Subsequent Proliferation
John W. Chen, C. Aderman, Kip M. Connor, N. Liu +2 more
20070 citations
Semantic Scholar
Bone Marrow Transplantation Into the Vitreous Cavity Augmented Vascular Recanalization After Hyperoxic Vascular Dropouts
H. Yamada, K. Minamino, E. Yamada, A. Higuchi +1 more
20060 citations
Semantic Scholar
Is Spontaneously Diabetic Torii Rat a Model for Human Diabetic Retinopathy
H. Yamada, E. Yamada, A. Higuchi, M. Matsumura
20050 citations
Semantic Scholar
Effect of Anti–hyperlipidemia drug against retinal neovascularization.
H. Yamada, A. Higuchi, E. Yamada, M. Matsumura
20040 citations
Semantic Scholar
Localization of Hard Exudates in Eyes with Diabetic Retinopathy Using Optical Coherence Tomography 3 (OCT3)
K. Minamino, Haruhiko Yamada, Emi Kawai, Y. Fujiseki +5 more
20040 citations
Semantic Scholar
Inhibitory Effect of St. John’s wort and Hypericin on Retinal and Choroidal Neovascularization.
A. Higuchi, H. Yamada, E. Yamada, M. Matsumura
20040 citations
Semantic Scholar
A new strategy for transplantation of bone marrow stem cells into the retina.
K. Minamino, Y. Adachi, H. Yamada, A. Higuchi +5 more
20040 citations
Semantic Scholar
Inhibitory Effect of Quinapril on Retinal and Choroidal Neovascularization
H. Yamada, E. Yamada, A. Higuchi, M. Matsumura
20030 citations
Semantic Scholar
Inhibitory Effect of Retinal and Choriodal Neovascularization by Candesartan
E. Yamada, H. Yamada, A. Higuchi, M. Matsumura
20030 citations
Semantic Scholar

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